• 한국자기공명학회논문지
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• 제20권1호
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• pp.27-35
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• 2016

NMR spectrometer has been regarded as essential tool for structure elucidation in variable scientific field as like organic synthesis, natural product and macro protein research. Also NMR can be applied for defining dynamic behavior like ligand and receptor binding. One of advantage of research with NMR is that to be great confident to confirm structure and the measured sample could be recovered. Nevertheless NMR also has a weak points than other spectroscopic methods that require a lot of time for interpreting acquired spectrum and running time due to low sensitivity. For last two decade Bruker has developed hardware and software solution for overcome those weak points. In order to overcome low sensitivity Bruker introduced Cryo and Micro diameter probe head technology. And researcher can reduce the time for routine spectrum processing and interpretation works due to lots of introductions in software solutions for quantification, identification and statistics analysis. With four examples, this article describing those new hardware and software solutions in field of recent pharmaceutical research as follows. - New Horizons for NMR in the Biopharmaceutical Industry - The development and application of solid-state NMR spectroscopy (SSNMR) in pharmaceutical analysis - Assisted NMR Data Interpretation in Synthetic Chemistry - Complete Analysis of New Psychoactive Substances Using NMR.

• 한국전산유체공학회지
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• 제10권1호
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• pp.107-112
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• 2005

A cross-flow fan is generally used on the region within the low static pressure difference and the high flow rate. It relatively makes high dynamic pressure at low rotating speed because a working fluid passes through an impeller blade twice and blades have a forward curved shape. At off-design points, there are a rapid pressure head reduction, a noise increase and an unsteady flow. Those phenomena are remarkably influenced by the setting angle of a stabilizer. Therefore, it should be considered how the setting angle of a stabilizer affects on the performance and the flow fields of a cross-flow fan. It is also required to investigate the effect of the volumetric flow rate before occurring stall. Two-dimensional, unsteady governing equations are solved using a commercial code, STAR-CD, which uses FVM. PISO algorithm, sliding grid system and standard k - ε turbulence model are also adopted. Pressure and velocity profiles with various setting angles are graphically depicted. Furthermore, the meridional velocity profiles around the impeller are plotted with different flow rates for a given rotating speed.

• 대한기계학회논문집
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• 제7권2호
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• pp.161-167
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• 1983

In this study the phenomenon of cutting stress which arises on cutting tools and work pieces in cutting process is investigated by rake angle of cutting tools and feed for this measurement, P$_{s}$-1 (high modulus, photolastic Inc.) was used as a cutting tool, P$_{s}$-3 (medium modulus, photolastic Inc.) was used as work piece and reduction apparatus was attached to the head stock, and orthogonal cutting was adapted as a cutting method and transparent glass was used to block the strain in the orientation of thickness. The followings are the results of this study. (1) Photoelastic experimental equipments have made it possible to make dynamic measurement and analyze stress distribution in cutting tool and work piece surface which has hitherto been conducted only in static measurement and analyzing method. (2) The maximum stress arising at tools and work pieces in cutting process is on the tool edge tip, and the maximum stress arising on the tip of cutting tools is equal to that on the contacting area of work pieces in values. (3) The distributions of maximum shear stress on certain parts of the cutting tools and work pieces are as follows; for cutting tools, .alpha.=12.deg., .alpha.=0.deg., .alpha.=-12.deg. in order, and for work pieces, .alpha.=-12.deg., .alpha.=0.deg., .alpha.=12.deg. in opposite order.der.

• International Journal of Aeronautical and Space Sciences
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• 제3권2호
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• pp.59-66
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• 2002

A vertical test stand based on launcher propulsion system was constructed and several tests for the determination of cyclogram were carried out. To make an accurate estimation, static and dynamic pressures were measured and analyzed. Especially, static pressure measurements using fast response sensors without extension tubes were used to determine operation sequence more evidently. The standard operation times of final valves were determined in cold flow tests with an engine head, and fire formation time in combustion chamber was checked in an ignition test with an ignitor only. On the basis of these tests, ignition sequence was established and combustion test cyclogram was finally determined. According to combustion test, test results were well matched with the determined cyclogram within 0.05 sec.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제9권4호
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• pp.1359-1375
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• 2015

Energy efficiency is critical for Wireless Sensor Networks (WSNs) since sensor nodes usually have very limited energy supply from battery. Sleep scheduling and nodes cooperation are two of the most efficient methods to achieve energy conservation in WSNs. In this paper, we propose an adaptive energy optimization approach for target tracking applications, called Energy-Efficient Node Coordination (EENC), which is based on the grid structure. EENC provides an unambiguous calculation and analysis for optimal the nodes cooperation theoretically. In EENC, the sleep schedule of sensor nodes is locally synchronized and globally unsynchronized. Locally in each grid, the sleep schedule of all nodes is synchronized by the grid head, while globally the sleep schedule of each grid is independent and is determined by the proposed scheme. For dynamic sleep scheduling in tracking state we propose a multi-level coordination algorithm to find an optimal nodes cooperation of the network to maximize the energy conservation while preserving the tracking performance. Experimental results show that EENC can achieve energy saving of at least 38.2% compared to state-of-the-art approaches.

• 대한관절경학회지
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• 제2권1호
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• pp.1-3
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• 1998

The PCL reconstruction in chronic isolate PCL reconstruction was still controversy. 1) In isolate PCL deficient knee, functionally not so bad as like ACL deficient knee. 2) The result of the PCL reconstruction was not as good as ACL reconstruction. Therefore, isolate PCL injuries has been treated as nonoperatively. Hey Grovere, who was the first to attempt an intra-articular reconstruction of the PCL, utilized the semi-tendinous tendon other static procedures have been described in only a few cases with very limited follow-up. Dynamic procedures utilizing the medial head of the gastrocnemius has been reported by Hugston and Degenhardt, Kennedy and Grainger, and Insall and Hood. These procedures did not improve static stability. Dr Clancy, who was introduce the use of BPTB for the PCL reconstruction transtibial and femoral tunnel. From 1995, untill early 1990 PCL reconstruction was done as tend as placement of the isometric point. Physiometic placement of Anatomical placement of the femoral tunnel in PCL reconstruction were introduced in 1995. Tibial Inlay Technique was reported by Dr Berg in 1995. The main advantage of the tibial Inlay Technique was to avoid fraying of the graft at the posterior tibial tunnel orifice. In complete PCL ruptured and severely posterior unstable knee, dual femoral tunnel technique will be to get better result than one bundle technique. To achieve restoration of normal posterior laxity, it is critical to address the posterior as well as the posterolateral structures. Futher research is necessary to evaluate new surgical approches such as double-bundle reconstructions and tibial inlay techniques as well as improved techniques for capsular and collateral ligament injuries.

• Journal of Korean Neurosurgical Society
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• 제40권3호
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• pp.189-192
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• 2006

Spontaneous dissection of the anterior cerebral artery is an unusual cause of subarachnoid hemorrhage. We present a case of a dissecting aneurysm of the anterior cerebral artery presenting with subarachnoid hemorrhage. A 51-year-old woman presented to our hospital with severe headache. Neurological examination demonstrated neck stiffness, decreased visual acuity of the left eye, and left ankle weakness. Computed tomographic scans showed subarachnoid hemorrhage. The initial cerebral angiogram demonstrated a slightly narrowed caliber and mild poststenotic dilation of the right A1 segment. A second cerebral angiogram 14 days later revealed no change in the focal narrowing of the proximal A1 segment but marked progression of the dilatation of the distal A1 segment. Right pterional craniotomy was performed. A sausage-like dilation of the right A1 segment was found with no definite mural hematoma. This abnormal right A1 segment was wrapped with a Sundt clip. A postoperative computed tomographic scan revealed Infarction of the right head of the caudate nucleus and the anterior limb of the right internal capsule. If a dissecting aneurysm is suspected, serial angiographic studies should be performed because of the possibility of dynamic changes over a short period.

• 대한인간공학회지
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• 제34권3호
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• pp.235-245
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• 2015

Objective: The purpose of this study is to develop visual complexity metrics based on theoretical bases. Background: With the development of IT technologies, drivers process a large amount of information caused by automotive human-machine interface (HMI), such as a cluster, a head-up display, and a center-fascia. In other words, these systems are becoming more complex and dynamic than traditional driving systems. Especially, these changes can lead to the increase of visual demands. Thus, a concept and tool is required to evaluate the complicated systems. Method: We reviewed prior studies in order to analyze the visual complexity. Based on complexity studies and human perceptual characteristics, the dimensions characterizing the visual complexity were determined and defined. Results: Based on a framework and complexity dimensions, a set of metrics for quantifying the visual complexity was developed. Conclusion: We suggest metrics in terms of perceived visual complexity that can evaluate the in-vehicle displays. Application: This study can provide the theoretical bases in order to evaluate complicated systems. In addition, it can quantitatively measure the visual complexity of In-vehicle information system and be helpful to design in terms of preventing risks, such as human error and distraction.

• 융합보안논문지
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• 제12권4호
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• pp.91-96
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• 2012

무선 네트워크의 많은 분야 중에서 MANET(Mobile Ad-hoc Network)은 상당히 발전이 되어있는 기술이다. MANET을 구성하는 노드들은 다중 홉 무선 연결을 이용하여 데이터 전달을 하게 된다. 이러한 환경에서 노드들의 데이터 접근 성능과 가용성을 향상시킬 수 있는 방법이 캐싱 기법이다. 기존의 많은 연구들은 이동 노드들의 다중 홉 연결을 향상시키기 위해 동적인 라우팅 프로토콜에 대해 많은 연구가 이루어져왔다. 그러나 노드들의 이동으로 인하여 유효한 캐시 정보의 관리 및 유지가 쉽지 않다. 본 논문에서는 이동 노드가 원하는 정보의 캐시 발견시 오버헤드를 줄이고 노드들의 이동으로 인한 연결 관리를 위해 클러스터 기반 캐싱 기법을 제안하였다. 그리고 각 클러스터 헤드에서 유효한 캐시 테이블을 유지할 수 있도록 하기 위해 HLP를 이용하였다. 본 논문에서 제안한 기법의 효율성은 실험을 통해 확인하였다.

• 융합보안논문지
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• 제14권7호
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• pp.17-22
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• 2014

MANET은 빠르게 네트워크를 구축할 수 있다는 특징 때문에 많은 분야에서 활용되고 있다. 그러나 무선 네트워크의 특성과 노드들의 이동으로 인해 많은 보안 위협에 노출되어 있다. 특히 그중에서도 라우팅 프로토콜의 취약점을 이용한 공격이 증가하고 있으며 그 피해 또한 매우 증가하고 있는 설정이다. 본 논문에서는 안전한 라우팅 프로토콜 제공을 위한 two-level 인증 구조를 제안하였다. 제안한 기법에서는 네트워크에 참여하는 노드들에 대하여 신뢰도를 기반으로 한 인증 평가를 실시하여 인증서를 발급해주며, 인증서를 발급받은 노드만이 데이터 전송을 수행하게 된다. 그리고 인증서를 발급받은 노드가 데이터 전송시 제어 패킷의 정보와 자신이 관리하는 PIT 정보를 비교 및 분석하여 악의적인 노드들에 대한 탐지를 수행하게 된다. Ns-2 시뮬레이터를 이용하여 본 논문에서 제안한 기법의 성능을 평가하였으며, 실험을 통하여 우수한 성능을 확인하였다.