• Journal of Chest Surgery
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• v.23 no.1
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• pp.152-157
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• 1990

A clinical study for thymectomy for 23 patients in Myasthenia Gravis was done between May, 1982 and July, 1989. at the department of Thoracic and Cardiovascular Surgery, College of Medicine, Han Yang University. Among Z3 patients, male to female ratio was 11: 12 and Age of onset was ranged from 15 years-old to 52 years-old. Previous symptom duration from diagnosis until operation was ranged from 2 months to 96 months, and Mean duration was 28.74 months. The severity of disease was classified by Osserman`s classification preoperatively. In histopathology of thymus, Thymic hyperplasia 7 cases, Thymoma 7 cases, Invasive thymoma 3 cases, Within Normal Limit 5 cases, and Thymic Atrophy 1 case. Correlation between preoperative symptom duration and postoperative clinical course was statistically significant. The shorter of preoperative symptom duration, The better of postoperative clinical course. Grading of postoperative course was classified by Papatestas in 1975. Follow-up for postoperative course was ranged from 3 months to 7 year and 4 months, Cases of complete remission 1 year postoperative period were 9 cases and cases of Improvement were 8 cases, So totally 17 cases among 23 cases[73.91%] found good results.

• The Transactions of the Korean Institute of Electrical Engineers D
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• v.55 no.10
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• pp.458-463
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• 2006

The purpose of this work is to investigate the fundamental properties of the gradual muscle force potentiation. We investigated the dependence of force potentiation on both the pulse-amplitude and the pulse-duration with different ramp-up time. The experimental results showed that the force increment ratio (FIR) during constant electrical stimulation decreased with pulse-amplitude and also with pulse-duration. The FIR was greater with short ramp-up time in both the pulse-amplitude and pulse-width modulation. The feasible mechanism might be that the myosin light chain phosphorylation induces the force potentiation and it occurs only in the fast type muscle fibers which are recruited first. These observations indicate that muscle potentiation must be understood well for the accurate control of muscle force.

• Phonetics and Speech Sciences
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• v.3 no.1
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• pp.15-22
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• 2011

The purposes of this study are (1) to investigate the correlation between English word-final stop and the duration of vowels before word-final stop and (2) to suggest a way to detect pronunciation errors and teach the pronunciation of English word-final stops. For these purposes, 18 Korean speakers' production was recorded and analysed using Speech Analyzer and their production was compared with that of native English speakers. In addition, two native English speakers evaluated the subjects' pronunciation. The major findings are the voicing dependent effect of the English vowels produced by native Korean speakers is lower than that of native English speakers; Korean speakers release English word-final stops less than native English speakers; and the pronunciation of English word-final stops and the duration of adjacent vowels are closely related in that the pronunciation score of final stops and the ratio of vowels between the vowels before voiced stops and voiceless stops are correlated. In addition, this study concludes with pedagogical suggestions that may be useful for English pronunciation teaching.

• Biomolecules & Therapeutics
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• v.27 no.5
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• pp.435-441
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• 2019

The capsaicin receptor TRPV1 (transient receptor potential vanilloid 1) has been an object of intense interest for pharmacological development on account of its critical role in nociception. In the course of structure activity analysis, it has become apparent that TRPV1 ligands may vary dramatically in the rates at which they interact with TRPV1, presumably reflecting differences in their abilities to penetrate into the cell. Using a fast penetrating agonist together with an excess of a slower penetrating antagonist, we find that we can induce an agonist response of limited duration and, moreover, the duration of the agonist response remains largely independent of the absolute dose of agonist, as long as the ratio of antagonist to agonist is held constant. This general approach for limiting agonist duration under conditions in which absolute agonist dose is variable should have more general applicability.

• Clinical and Experimental Pediatrics
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• v.61 no.10
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• pp.315-321
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• 2018

Purpose: To investigate the effectiveness of transient intubation for surfactant administration and extubated to nasal continuous positive pressure (INSURE) for treatment of respiratory distress syndrome (RDS) and to identify the factors associated with INSURE failure in extremely premature infants. Methods: Eighty-four infants with gestational age less than 28 weeks treated with surfactant administration for RDS for 8 years were included. Perinatal and neonatal characteristics were retrospectively reviewed, and major pulmonary outcomes such as duration of mechanical ventilation (MV) and bronchopulmonary dysplasia (BPD) plus death at 36-week postmenstrual age (PMA) were compared between INSURE (n=48) and prolonged MV groups (n=36). The factors associated with INSURE failure were determined. Results: Duration of MV and the occurrence of BPD at 36-week PMA were significantly lower in INSURE group than in prolonged MV group (P<0.05), but BPD plus death at 36-week PMA was not significantly different between the 2 groups. In a multivariate analysis, a reduced duration of MV was only significantly associated with INSURE (P=0.001). During the study period, duration of MV significantly decreased over time with an increasing rate of INSURE application (P<0.05), and BPD plus death at 36-week PMA also tended to decrease over time. A low arterial-alveolar oxygen tension ratio (a/APO2 ratio) was a significant predictor for INSURE failure (P=0.001). Conclusion: INSURE was the noninvasive ventilation strategy in the treatment of RDS to reduce MV duration in extremely premature infants with gestational age less than 28 weeks.

• Journal of Korea Water Resources Association
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• v.34 no.5
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• pp.415-426
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• 2001

After Disaster Impact Assessment(DIA) Program was particed, the wide variety of hydrological data are estimated by introducing the concept of critical storm duration to calculate the stormwater impoundments as the alternative of increasing runoff due to many developments. Critical storm duration is varied by a lot of hydraulic structures, drainage characteristics, temporal distribution of design rainfall, return period, and runoff models. In this study the methods of estimating the proper volume to design the stormwater impoundments are proposed to determine the required volume by comparing and analyzing the maximum stormwater impoundments in accordance with the impoundment volume and rainfall duration by using the concept of storage ratio presented in the existing studies. The methods of determining the critical storm duration of design rainfall which cause the maximum load from the runoff hydrograph will be studied as analyzing rainfall-runoff using the various runoff models and observed data.

• Clinical and Experimental Pediatrics
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• v.61 no.11
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• pp.362-365
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• 2018

Purpose: This study aimed to analyze changes in QRS duration and cardiothoracic ratio (CTR) following pulmonary valve replacement (PVR) in patients with tetralogy of Fallot (TOF). Methods: Children and adolescents who had previously undergone total repair for TOF (n=67; median age, 16 years) who required elective PVR for pulmonary regurgitation and/or right ventricular out tract obstruction were included in this study. The QRS duration and CTR were measured pre- and postoperatively and postoperative changes were evaluated. Results: Following PVR, the CTR significantly decreased (pre-PVR $57.2%{\pm}6.2%$, post-PVR $53.8%{\pm}5.5%$, P=0.002). The postoperative QRS duration showed a tendency to decrease (pre-PVR $162.7{\pm}26.4$ msec, post-PVR $156.4{\pm}24.4$ msec, P=0.124). QRS duration was greater than 180 msec in 6 patients prior to PVR. Of these, 5 patients showed a decrease in QRS duration following PVR; QRS duration was less than 180 msec in 2 patients, and QRS duration remained greater than 180 msec in 3 patients, including 2 patients with diffuse postoperative right ventricular outflow tract hypokinesis. Six patients had coexisting arrhythmias before PVR; 2 patients, atrial tachycardia; 3 patients, premature ventricular contraction; and 1 patient, premature atrial contraction. None of the patients presented with arrhythmia following PVR. Conclusion: The CTR and QRS duration reduced following PVR. However, QRS duration may not decrease below 180 msec after PVR, particularly in patients with right ventricular outflow tract hypokinesis. The CTR and ECG may provide additional clinical information on changes in right ventricular volume and/or pressure in these patients.

• Safety and Health at Work
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• v.12 no.3
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• pp.311-316
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• 2021

Background: The present study investigated the association between two domains of physical activity (occupational physical activity [OPA] and leisure-time physical activity [LTPA]) and sleep duration. Methods: We investigated 3,421 paid workers from the Korea National Health and Nutrition Examination Survey, 2014-2015. Sleep duration was categorized into three categories (short for less than 5 h, optimal for 5-9 h, and long for more than 9 h). OPA and LTPA were defined in terms of answers to relevant questions. Odds ratios were calculated for sleep duration according to each physical activity domain using multinomial logistic regression models. Results: There were 464 subjects (13.6%) who showed short sleep duration, and 169 subjects (4.9%) who showed long sleep duration. Prevalence of OPA and LTPA was higher in male workers than in female workers (for OPA: 3.67% and 1.76%, respectively, p = 0.0108; for LTPA: 16.14% and 6.07%, respectively, p < 0.0001). The odds ratio of OPA for long sleep duration in female workers was 3.35 (95% confidence interval, 1.37-8.21). Otherwise, LTPA was not associated with sleep duration in female paid workers, nor both physical activity domains in male paid workers. Conclusion: Female paid workers with work-related physical activity were at risk of oversleeping. These findings also suggested that physical activity has distinct associations with sleep duration according to the physical activity domains and sex.

• Korean Journal of Soil Science and Fertilizer
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• v.20 no.1
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• pp.23-28
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• 1987

A series of field and laboratory experiments were conducted to find out the changes of some soil chemical constituents in different soil depth with three different soil textures as Bongnam-clayey, Gwanghwal-silty loam and Mangyeong fine sandy soil on the assessment of reclamation duration in Fluvio-marine soil. The result obtained were summarized as follows; 1. Exchangeable potassium, calcium, magnessium, sodium with manganes, silica and cation exchange capacity were remarkably decreased with assessment of reclamation duration. Decreasing tendency was pronounced more in sandy soil than silty loam or clayly soil. 2. Soil organic matter content in top soil was increased with increasing of reclamation years. From reclamation time, about 30 years in clayly and about 80 years in silty loam and sandy soil were necessary for the maintanance of averaged organic matter content to 2.5%. 3. Potassium activity ratio ($K/{\sqrt{Ca+Mg+Na}}$) was differed with soil depth, soil texture and assessment of reclamation duration. About 50 years is may be necessary for the maintanance of potassium activities ratio in ordinary paddy soil of 0.05-0.2. 4. Percent of adsorbed sodium (PAS), ratio of adsorbed sodium (RAS) and ratio of sodium adsorbtion(RSA) were remarkably decreased with assessment of reclamation duration. Specially, decreasing tendency was pronounced more in sandy soil than silty loam and clayly soil 5. Amount of clay content in subsoil was appearently decreased during 30 years of reclamation, but clay contents in top soil was appearently decreased 50 years after reclamation.

• Transactions of the Korean Society of Automotive Engineers
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• v.15 no.1
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• pp.64-70
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• 2007

Raising exhaust gas temperature during cold-start period is very crucial to improve emission performance of SI engines because it enhances the performance of catalyst in the early stage of engine start. In this study, control variables such as ignition timing, idle speed actuator(ISA) opening and fuel injection duration were extensively investigated to analyze variations in exhaust gas temperature and engine stability during cranking period. Experimental results showed that spark timing affected engine stability and exhaust gas temperature but the effects were small. On the other hand, shortened injection duration and increased ISA opening led to a significant increase in exhaust gas temperature. Under such conditions, increase in cranking time was also observed, showing that it becomes harder to start the engine. Based on these observations, a pseudo fuel-air ratio, defined as a ratio of fuel injection time to degree of ISA opening, was introduced to analyze the experimental results. In general, decrease in pseudo fuel-air ratio raised exhaust gas temperature with the cost of stable and fast cranking. On the contrary, an optimal range of the pseudo fuel-air ratio was found to be between 0.3 to 0.5 where higher exhaust gas temperatures can be obtained without sacrificing the engine stability.