• Title/Summary/Keyword: duodenal

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Percutaneous Biliary Metallic Stent Insertion in Patients with Malignant Duodenobiliary Obstruction: Outcomes and Factors Influencing Biliary Stent Patency

  • Ji Hye Kwon;Dong Il Gwon;Jong Woo Kim;Hee Ho Chu;Jin Hyoung Kim;Gi-Young Ko;Hyun-Ki Yoon;Kyu-Bo Sung
    • Korean Journal of Radiology
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    • v.21 no.6
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    • pp.695-706
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    • 2020
  • Objective: To investigate the technical and clinical efficacy of the percutaneous insertion of a biliary metallic stent, and to identify the factors associated with biliary stent dysfunction in patients with malignant duodenobiliary obstruction. Materials and Methods: The medical records of 70 patients (39 men and 31 women; mean age, 63 years; range, 38-90 years) who were treated for malignant duodenobiliary obstruction at our institution between April 2007 and December 2018, were retrospectively reviewed. Variables found significant by univariate log-rank analysis (p < 0.2) were considered as suitable candidates for a multiple Cox's proportional hazard model. Results: The biliary stents were successfully placed in all 70 study patients. Biliary stent insertion with subsequent duodenal stent insertion was performed in 33 patients and duodenal stent insertion with subsequent biliary stent insertion was performed in the other 37 study subjects. The median patient survival and stent patency time were 107 days (95% confidence interval [CI], 78-135 days) and 270 days (95% CI, 95-444 days), respectively. Biliary stent dysfunction was observed in 24 (34.3%) cases. Multiple Cox's proportional hazard analysis revealed that the location of the distal biliary stent was the only independent factor affecting biliary stent patency (hazard ratio, 3.771; 95% CI, 1.157-12.283). The median biliary stent patency was significantly longer in patients in whom the distal end of the biliary stent was beyond the distal end of the duodenal stent (median, 327 days; 95% CI, 249-450 days), rather than within the duodenal stent (median, 170 days; 95% CI, 115-225 days). Conclusion: The percutaneous insertion of the biliary metallic stent appears to be a technically feasible, safe, and effective method of treating malignant duodenobiliary obstruction. In addition, a biliary stent system with a distal end located beyond the distal end of the duodenal stent will contribute towards longer stent patency in these patients.

Duodenal Perforation Caused by an Inferior Vena Cava Filter

  • Bae, Mi-Ju;Chung, Sung-Woon;Lee, Chung-Won;Kim, Sang-Pil;Song, Seung-Hwan
    • Journal of Chest Surgery
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    • v.45 no.1
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    • pp.69-71
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    • 2012
  • The inferior vena cava (IVC) filter is known as an effective and safe method for preventing fatal pulmonary thromboembolism in patients with deep vein thrombosis. Usually, the remaining IVC filters are asymptomatic and do not cause clinical problems. We report a case of duodenal perforation caused by a remaining IVC filter.

The Effects of Hyang-Sa-Yuk-Gun-Ja-Tang and Oh-Pe-San on The Gastric Mucosal Repair (위장관(胃腸管) 점막층(粘膜層)의 회복(恢復)에 향사육군자탕(香砂六君子湯)과 오패산(烏貝散)이 미치는 영향(影響))

  • Chang, Hen-Yel;Kang, Yoon-Ho
    • The Journal of Dong Guk Oriental Medicine
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    • v.2 no.1
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    • pp.127-137
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    • 1993
  • In order to investigate the clinical efficiency based on Oriental Medical References of Hyang-Sa-Yuk-Gun-Ja-Tang and Oh-Pe-San, histological studies have been done by using the experimental animal. The following results were obtained. 1. The Hyang-Sa-Yuk-Gun-Ja-Tang showed a significant promoting effect of repair on the epithelial layer from the basement membrane of duodenal ulcer in rats. 2. The Oh-Pe-San showed efficiencies about repair of the necrosis in epithelial layer on the acute gastritis in rats. According to above results, it is concluded that Oh-Pe-San and Hyang-Sa-Yuk-Gun-Ja-Tang were recognized to be effective on the acute gastritis and the duodenal ulcer in rats, and this study may suggest a clinical guidance to the prescriptions for the treatment of gastritis end gastric ulcer.

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Factors Associated with Gastric and Duodenal Neuroendocrine Tumor Development

  • Kwangwoo Nam;Su Youn Nam
    • Journal of Digestive Cancer Research
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    • v.12 no.1
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    • pp.1-5
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    • 2024
  • The incidence and prevalence of upper gastrointestinal neuroendocrine tumors (NETs), including gastric NETs (GNETs) and duodenal NETs (DNETs), have been gradually increasing. These trends may be associated with the increased use of health checkups, which includes upper endoscopy, in conjunction with better disease recognition. However, the clinical factors associated with GNETs and DNETs remain unknown; previous studies revealed discrepancies. Recently, metabolic disorders have been indicated as potential factors that are associated with GNETs and DNETs. This review summarizes the results of previous studies and briefly introduces the results of a recent Korean multicenter study on the factors associated with GNETs and DNETs.

Portal Absorption of Feed Oligo-peptides in Chickens

  • Wang, Lijuan;Ma, Qiugang;Cheng, Ji;Guo, Baohai;Yue, Hongyuan
    • Asian-Australasian Journal of Animal Sciences
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    • v.17 no.9
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    • pp.1277-1280
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    • 2004
  • The effect of duodenal infusion with feed oligo-peptide solution on portal absorption of amino acids was investigated in poultry under unanaesthetized conditions. Four peptide solutions were used in the experiment: enzymatic hydrolysates from fish meal, soybean meal, cottonseed meal and rapeseed meal proteins with average molecular weights less than 3,000 Da and 1,000 Da, respectively. Intestinal absorptions of these oligo-peptide solutions were compared by determining the concentration of free amino acid (FAA) in portal blood after the duodenal administrations of oligo-peptide solutions. Absorptive intensity and balance were used to estimate the intestinal absorption rate of amino acids. The absorptive intensities of amino acids were highest for the fish and soybean meal oligo-peptides. The ratios of amino acids absorbed in the portal blood from fish and soybean meal oligo-peptides were more similar to the composition of the infused amino acids than that observed from the cottonseed and rapeseed meal oligo-peptides. A positive correlation was found between absorption rate and proportion of PAA in the oligo-peptides. The higher absorption rate could be contributed to the higher proportion of peptide bound amino acids (PAA). The results suggest that fish and soybean meal protein are significantly more easily hydrolyzed into oligo-peptides (p<0.05) in the gastrointestinal tracts of poultry and as such can be utilized more effectively by body tissues.

THE EFFECT OF PHYSICAL CHARACTERISTICS OF HAY DIETS ON PHOSPHORUS METABOLISM IN SHEEP

  • Junluang, W.;Yano, F.;Yano, H.;Kawashima, R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.5 no.3
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    • pp.505-510
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    • 1992
  • The experiments were carried out to study the effect of physical forms of hay diet on phosphorus metabolism by offering sheep roughage diets containing a low phosphorus content. The sheep were fed coarse hay, short hay or finely ground pelleted hay. The physical forms of hat diet had little effect on the pathway of phosphorus excretion. In all groups, the most of phosphorus was excreted in feces and urinary phosphorus excretion was negligible. Duodenal fluid flow, rumen fluid outflow and estimated salivary flow appeared to be relatively high in sheep fed the coarse hay diet as compared to those in sheep fed the finely ground diet. The amount of phosphorus flow to the duodenum tended to be high in the coarse diet group as compared to those in other two groups. On the other hand, phosphorus concentrations in the duodenal fluid and the rumen fluid were lower in sheep fed the coarse hay diet than those in sheep fed the ground hay. Net intestinal phosphorus absorption tended to be higher in sheep fed the coarse hay than that in sheep fed the ground hay or pelleted hay. However, a negative phosphorus balance was observed in the coarse hay diet group although a positive phosphorus balance was found in other two groups. It was considered that salivary phosphorus secretion was greater than the amount of salivary phosphorus reabsorbed from the intestine, resulting in the negative of phosphorus balance in sheep fed the coarse hay.

Digestive Neuroendocrine Tumor Distribution and Characteristics According to the 2010 WHO Classification: a Single Institution Experience in Lebanon

  • Kourie, Hampig Raphael;Ghorra, Claude;Rassy, Marc;Kesserouani, Carole;Kattan, Joseph
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.5
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    • pp.2679-2681
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    • 2016
  • Background: Gastro-entero-pancreatic neuroendocrine neoplasms (GEP-NEN) are relatively rare tumors, not equally distributed in gastro-intestinal system. In 2010, a revised version of the WHO classification of GEP-NENs was published. This study reports for the first time the distribution and characteristics of GEP-NEN in a Lebanese population. Materials and Methods: This descriptive retrospective study concerns all the digestive neuroendocrine tumors with their characteristics diagnosed in $H\hat{o}tel$ Dieu de France in Beirut, Lebanon from 2001 to 2012, all the pathology reports being reanalyzed according to the latest WHO 2010 classification. The characteristics and features of GEP-NEN analyzed in this study were age, gender, grade and site. Results: A total of 89 GEP-NENs were diagnosed, representing 28.2% of all neuroendocrine tumors. The mean age of GEP-NEN patients was 58.7 years and the M/F sex ratio was 1.2. The primary localization was as follows: 21.3%(19) pancreatic, 18% (16) gastric, 15.7% (14) duodenal, 11.2% (10) appendix, 10.1% (9) intestinal, 10.1% (9) colorectal (7.9% colonic and 2.2% rectal), 5.6% (4) hepatic, 2.2% (2) ampulla, 1.1% (1) esophageal and 7.9%(5) NOS digestive (metastatic with unknown primary). Of the 89 patients with GEP-NEN, 56.2% (50) were diagnosed as grade I, 11.2% (10) as grade II, 20.2% (18) as grade III and 12.4% (11) were considered as mixed adeno-neuroendocrine carcinomas (MANEC). Conclusions: This study, one of the rare examples based on the 2010 WHO classification of neuroendocrine tumors in the literature, indicates that in the Lebanese population, all duodenal and appendicular tumors are G1 and the majority of MANEC tumors are gastric and pancreatic tumors. Moreover, more duodenal tumors and fewer rectal tumors were encountered in our study compared to European reports.