• Microbiology and Biotechnology Letters
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• v.36 no.4
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• pp.353-359
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• 2008

Hepatitis C virus (HCV) is known as the causative agent of blood transmitted hepatitis. Two viral proteins, E2 and NS5A, are known to exert interferon resistance of HCV via PKR pathway. Here, we report a third protein, the RNA-dependent RNA polymerase (NS5B) of HCV, induced interferon resistance inhibiting p56 pathway. p56 was shown to interact with p48 subunit of eukaryotic initiation factor 3 (eIF3). This interaction inhibited formation of ternary complex in translation initiation. Using dual reporter assay system, we observed that the translation decreased when interferon alpha was added to the culture. But, in the presence of HCV NS5B, the translation partly recovered. NS5B and p48 subunit of eIF3 were shown to interact. This interaction seems to inhibit the interaction between p48 and p56. This is the first report that a virus exerts interferon resistance via p56 pathway.

• International Journal of Automotive Technology
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• v.8 no.6
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• pp.697-704
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• 2007

Recently, a variable valve timing system has been widely adopted in internal combustion engine in order to improve the fuel economy and torque at low engine speed. In addition, it is known that varying valve timing according to the various engine operations could reduce exhaust gas, especially NOx, because of residual gas by valve overlap. In this study, to improve the low exhaust gas and fuel economy at part load condition, the residual gas and back flow of exhaust gas due to valve overlap were calculated computationally. Moreover, the characteristics of engine performances and NOx formations were investigated with the experiment of combination of intake and exhaust valve timing condition. Under these various valve operating conditions, the effects of both the positive valve overlap and negative valve overlap(valve underlap) were examined simultaneously. Finally, the characteristics of cyclic THC emission were analyzed by using Fast Response FID(FR-FID) in the cylinder, intake port and exhaust port positions. Besides, the effect of the different gradients of the valve timing change on engine performance was investigated and an optimum control strategy was suggested.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.8
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• pp.37-45
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• 2002

A two-dimensional unsteady, inviscid flow solver has been developed for the simulation of airfoil-vortex interactions on unstructured dynamically adapted meshes. The Euler solver is based on a second-order accurate implicit time integration using a point Gauss-Seidel relaxation scheme and a dual time-step subiteration. A vertex-centered, finite-volume discretization is used in conjunction with the Roe's flux-difference splitting. An unsteady solution-adaptive dynamic mesh scheme is used by adding and deleting mesh points to take account of both spatial and temporal variations of the flow field. The effect of vortex interaction on the aeroelastic displacement of an airfoil attached to the idealized two degree-of-freedom spring system is investigated.

• Korean Institute of Interior Design Journal
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• v.23 no.3
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• pp.83-91
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• 2014

As a applied art, Architecture is a synthetic art for dwelling and settlement. It has started with the origin of the human. and Artistical-technological indicator, include not only materiality but also immateriality such as history and society. After 20C, various categories of thinking is a undergoing rapid change. especially, beginning in 1900, The intrinsic value of "Fine Art" had lost their competitive power in the face of industrial revolution's mass production. and it has been displaced by a "new concept", such as a conveyance of meaning or rational way of thinking. This change means free from the tradition and custom of a past. for that reasons, Due to the nature of applied art, it always include design symbolism and designer's thinking is mainly processed in their own system of thinking. Symbolism for the art was distinguished from a general concept by the connotative meaning that called "the dual image". Therefore, at the start, this study will define about design and symbolism with a architecture as a applied art. then, Analysis the expression tendency of the contemporary architecture and modification. as a result, It aim to systematize mapping process and suggest the classification of various visual cue.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.63 no.8
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• pp.1085-1091
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• 2014

A model based SOC estimation scheme using parameter identification is described and applied to a Lithium-ion battery module that can be installed in electric vehicles. Simulation studies are performed to verify the effect of sensor faults on the SOC estimation results for terminal voltage sensor and load current sensor. The sensor faults should be detected and isolated as soon as possible because the SOC estimation error due to any sensor fault seriously affects the overall performance of the BMS. A new fault detection and isolation(FDI) scheme by which the fault of terminal voltage sensor and load current sensor can be detected and isolated is proposed to improve the reliability of the BMS. The proposed FDI scheme utilizes the parameter estimation of an input-output model and two fuzzy predictors for residual generation; one for terminal voltage and the other for load current. Recently developed dual polarization(DP) model is taken to develope and evaluate the performance of the proposed FDI scheme. Simulation results show the practical feasibility of the proposed FDI scheme.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.17 no.2
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• pp.145-152
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• 1999

JPL(Jet Propulsion Laboratory) has been routinely produced the precise GPS ephemeris and clock's correction parameter using data collected from globally distributed permanent GPS tracking stations, and has been offering the automated GPS data analysis(Precise Point Positioning： PPP) service by using them. In this study, after investigating the potential capacity of JPL's PPP service, the coordinates computation of the GPS base station by this service were investigated. For this, the dual frequency P codes data of 24 hours were observed from continuously operating four reference stations in USA. sent to the JPL's main computer through E-mail and/or ftp, and then were processed by Gipsy/Oasis-II (GOA-II) software with the precise GPS transmitter parameters. Centimeter-level positioning results were available to obtain in X, Y, Z geocentric rectangular coordinate system.

• Journal of the Korean Society for Aviation and Aeronautics
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• v.24 no.1
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• pp.10-15
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• 2016

In this study, The code-carrier divergence test was applied to GPS measurements, and the results were compared and analyzed. The GPS data used for the threshold determination were obtained from Global Navigation Satellite System permanent stations built by the Korea Aerospace Research Institute. At each permanent station, identical dual-frequency receiver and choke ring antenna with radome are installed. The analysis method, root mean square values were compared and analyzed for each permanent station and satellite. As a result, the root mean square value generally decreased as the satellite elevation angle increased although the trend was gentle. Threshold were finally selected based on the average and standard deviation of root mean square for each permanent station. For improving of availability and continuity in real-time operation when the threshold is over the limits, Code-Carrier divergence test values are initialized.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.31 no.6
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• pp.30-35
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• 2003

In this paper, the transverse strain was measured using polarization maintaining fiber Bragg grating(PMFBG) sensor. PMFBG sensor was fabricated using phase mask and Excidmer laser. The reflected wavelength of PMFBG sensor had dual peaks due to intrinsic birefringence. To find the polarization axes, peak sensitivity was measured under compression test. The signal characteristics of PMFBG sensor were also examined in embedding condition. The embedded PMFBG sensor in epoxy block was loaded for the transverse strain measurement, The wavelength-swept fiber laser(WSFL) was used to construct the PMFBG sensor system. Experiments showed that the PMFBG sensor could successfully measure the transverse strain.

• Computers and Concrete
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• v.5 no.6
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• pp.573-597
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• 2008

Among artificial intelligence-based computational techniques, adaptive neuro-fuzzy inference systems (ANFIS) are particularly suitable for modelling complex systems with known input-output data sets. Such systems can be efficient in modelling non-linear, complex and ambiguous behaviour of cement-based materials undergoing single, dual or multiple damage factors of different forms (chemical, physical and structural). Due to the well-known complexity of sulfate attack on cement-based materials, the current work investigates the use of ANFIS to model the behaviour of a wide range of self-consolidating concrete (SCC) mixture designs under various high-concentration sodium sulfate exposure regimes including full immersion, wetting-drying, partial immersion, freezing-thawing, and cyclic cold-hot conditions with or without sustained flexural loading. Three ANFIS models have been developed to predict the expansion, reduction in elastic dynamic modulus, and starting time of failure of the tested SCC specimens under the various high-concentration sodium sulfate exposure regimes. A fuzzy inference system was also developed to predict the level of aggression of environmental conditions associated with very severe sodium sulfate attack based on temperature, relative humidity and degree of wetting-drying. The results show that predictions of the ANFIS and fuzzy inference systems were rational and accurate, with errors not exceeding 5%. Sensitivity analyses showed that the trends of results given by the models had good agreement with actual experimental results and with thermal, mineralogical and micro-analytical studies.

• Earthquakes and Structures
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• v.12 no.5
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• pp.501-513
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• 2017

To investigate the seismic performance of Y-shaped eccentrically braced frames fabricated with high-strength steel (Y-HSS-EBFs), a shake table test of a 1:2 scaled three-story Y-HSS-EBF specimen was performed. The input wave for the shake table test was generated by the ground motions of El Centro, Taft, and Lanzhou waves. The dynamic properties, acceleration, displacement, and strain responses were obtained from the test specimen and compared with previous test results. In addition, a finite element model of the test specimen was established using the SAP2000 software. Results from the numerical analysis were compared with the test specimen results. During the shake table test, the specimen exhibited sufficient overall structural stiffness and safety but suffered some localized damage. The lateral stiffness of the structure degenerated during the high seismic intensity earthquake. The maximum elastic and elastoplastic interstory drift of the test specimen for different peak ground accelerations were 1/872 and 1/71, respectively. During the high seismic intensity earthquake, the links of the test specimen entered the plastic stage to dissipate the earthquake energy, while other structural members remained in the elastic stage. The Y-HSS-EBF is a safe, dual system with reliable seismic performance. The numerical analysis results were in useful agreement with the test results. This finding indicated that the finite element model in SAP2000 provided a very accurate prediction of the Y-HSS-EBF structure's behavior during the seismic loadings.