• Magazine of the Korean Society of Agricultural Engineers
• /
• v.44 no.7
• /
• pp.74-82
• /
• 2002

There are two major operation and management (O & M) systems in Korea, one by the Korea Agricultural and Rural Infrastructure Corporation (KARICO), a government corporation, and the other by non-KARICO, which includes Irrigation associations (IAs) and individual farmers under the supervision of city or county authorities. Main issues and constraints in the irrigation facility management are: (1) The dual system of the irrigation water management system; management by KARICO and that by IAs, and (2) From the commencement of KAICO in 2000, farmers were exempted from water charge. This is opposite to the international trend, which follows' user pay principle: Main specific strategies to improve irrigation management system are: (1) Introduction of water metering for water charge as well as water conservation, (2) Adoption of demand-oriented irrigation rather than supply-oriented to reduce waste of water, (3) To augment farmer's participation by forming water user associations, (4) To maintain consistency of government policy, (5) To promote roles of local governments, and (6) To reestablish the role of KARICO.

• Journal of the Korean Home Economics Association
• /
• v.40 no.4
• /
• pp.59-71
• /
• 2002

This study investigated the self wrapping made possible through the anonymity of cuber-space. According to the analysis of the data, which were collected from the online for 2 days, 2,168 respondents were grouped into three types: Those maintaining the strong sense of identity achievement), 53.8%, those experiencing confusion(identity diffusion), 38.3%, and those losing the sense of identity(foreclosure), 7.9%. Among the general respondents, it was reported that the case of sex wrapping was 11.4%, that of occupation, 40.1%, and that of marital status, 60.6%. Specially 11.4% of the sex wrapper took heterogeneous gender identity, while 7% performed dual sex roles. The rate of gender wrapping of female respondents was higher than that of male ones, which reflects female respondents' longing for male sex. Self-disparity between cyber-space and virtual-space was related with the type of self-identity and gender-identity. The rate of self-disparity between cuber-space and virtual-space was 9%. If it occurred continuously, it may cause individual mental division and maladjustment.

• BMB Reports
• /
• v.42 no.8
• /
• pp.475-481
• /
• 2009

Emerging data demonstrate pivotal roles for brain insulin resistance and insulin deficiency as mediators of cognitive impairment and neurodegeneration, particularly Alzheimer's disease (AD). Insulin and insulin-like growth factors (IGFs) regulate neuronal survival, energy metabolism, and plasticity, which are required for learning and memory. Hence, endogenous brain-specific impairments in insulin and IGF signaling account for the majority of AD-associated abnormalities. However, a second major mechanism of cognitive impairment has been linked to obesity and Type 2 diabetes (T2DM). Human and experimental animal studies revealed that neurodegeneration associated with peripheral insulin resistance is likely effectuated via a liver-brain axis whereby toxic lipids, including ceramides, cross the blood brain barrier and cause brain insulin resistance, oxidative stress, neuro-inflammation, and cell death. In essence, there are dual mechanisms of brain insulin resistance leading to AD-type neurodegeneration: one mediated by endogenous, CNS factors; and the other, peripheral insulin resistance with excess cytotoxic ceramide production.

• IMMUNE NETWORK
• /
• v.20 no.6
• /
• pp.45.1-45.16
• /
• 2020

IL-9 has been reported to play dual roles in the pathogenesis of autoimmune disorders and cancers. The collaboration of IL-9 with microenvironmental factors including the broader cytokine milieu and other cellular components may provide important keys to explain its conflicting effects in chronic conditions. In this review, we summarize recent findings on the cellular sources of, and immunological responders to IL-9, in order to interpret the role of IL-9 in the regulation of immune responses. This knowledge will provide new perspectives to improve clinical benefits and limit adverse effects of IL-9 when treating pathologic conditions.

• The Journal of the Korea Contents Association
• /
• v.20 no.11
• /
• pp.1-14
• /
• 2020

This study investigated the effects of SW-efficacy on computational thinking STEAM literacy and the dual mediation effects of interest and student engagement in the relationship between SW-efficacy, computational thinking and STEAM literacy in robot-utilized SW convergence education. For achieving this purpose, robot-utilized SW convergence education targeting 146 middle schools students were carried out, post-survey regarding SW-efficacy, computational thinking, STEAM literacy, interest, and learning engagement were conducted. Collected data were analyzed by SPSS macro process for analysis of the dual mediation effect. Results were as follows: first, SW-efficacy had a significant effect on computational thinking and STEAM literacy. Second, interest did not mediate the relationship between SW efficacy, computational thinking and STEAM literacy, while student engagement mediated it. Third, SW efficacy had a significant effect on computational thinking and STEAM literacy dual-mediating effect of interest and student engagement. These results imply the roles of SW efficacy, interest and student engagement to improve computational thinking and STEAM literacy in robot-utilized SW education and provide implications with regard to robot-utilized SW education and instructional directions.

• Journal of the Korea Institute of Building Construction
• /
• v.24 no.2
• /
• pp.239-248
• /
• 2024

The adjustment in guidelines for quality certification of recycled aggregate permitted the Quality Control Manager of a company specializing in recycled aggregate quality certification to concurrently assume the role of Environmental Management Manager. Analysis of the outcomes from the 2023 recycled aggregate quality certification follow-up management audit conducted by the certification agency revealed that in 95 out of 242 cases, constituting approximately 39% of the total cases, individuals held concurrent positions. Following the regulatory revision, there has been a notable proliferation of concurrent roles across various enterprises. Concerns arose regarding the potential neglect of quality control for certified recycled aggregates in comparison to scenarios where individuals are solely responsible for specific duties related to quality and environmental management. Audit results encompassing six aspects, including waste management, were evaluated on a scale of 6 points. A comparative analysis was conducted between the outcomes of 147 cases managed by dedicated personnel, as previously practiced, and 95 cases managed by individuals with concurrent roles. Although the average score of the latter group was marginally lower, no statistically significant disparity was observed between the two groups. Consequently, apprehensions regarding the oversight of quality control stemming from the allowance of concurrent roles appear unfounded. Within the context of recent regulatory revisions, permitting concurrent roles in managerial capacities is deemed an appropriate relaxation of regulations.

• Journal of the Korean earth science society
• /
• v.33 no.5
• /
• pp.377-394
• /
• 2012

To elucidate the mechanism associated with the development of heavy precipitation system, a field experiment was carried out in Jejudo (or Jeju Island) and Marado, Korea from 22 June to 12 July 2006. The synoptic atmospheric conditions were analyzed using the National Centers for Environmental Prediction-National Center for Atmospheric Research's (NCEP/NCAR) reanalyzed data, weather maps, and sounding data. The kinematic characteristics of each precipitation system were investigated by dual Doppler radar analysis. During the field experiment, data of four precipitation events with more than 20 mm rainfall were collected. In F case (frontal precipitation), a typical Changma front was dominant and the observation field was fully saturated. However there was no convective instability near the surface. LF case (low pressure accompanied with Changma front) showed strong convective instability near the surface, while a strong convergence corresponded to the low pressure from China accompanied with Changma front. In FT case (Changma front indirectly influenced by typhoon), the presence of a convective instability indicated the transport of near surface, strong additional moisture from the typhoon 'EWINIAR'. The convergence wind field was ground to be located at a low level. The convective instability was not significant in T case (precipitation of the typhoon 'EWINIAR'), since the typhoon passed through Jejudo and the Changma front was disappeared toward the northeastern region of the Korean peninsula. The kinematic (convergence and divergence) characteristics of wind fields, convective instability, and additional moisture inflow played important roles in the formation and development of heavy precipitation.

• Environmental and Resource Economics Review
• /
• v.18 no.4
• /
• pp.745-766
• /
• 2009

It is not valid to measure the degree of market power based on the markup of price over marginal market cost in an industry for which the market price of some inputs is not available because those inputs are then excluded in estimating the dual total cost function. If the roles of those inputs are ignored, the markup of price over marginal market cost is likely to be positive in the perfectly competitive industry. In order to have accurate market power markups for the environmentally regulated Korean iron and steel industry, in which the market price of raw material and the price of abatement capital are hard to obtain, in this paper, a dual cost function is derived given the optimal quantities of raw material and abatement capital, and then estimated jointly with the supply relation. The annual average degree of market power for the industry is estimated to be 0.49 over the period 1982~2001. Ignoring environmental regulation would overstate the degree of market power by about 8 percent.

• Asian Pacific Journal of Cancer Prevention
• /
• v.17 no.3
• /
• pp.1285-1292
• /
• 2016

Background: It is well established that mutations in the BRCA1 gene are a major risk factor for breast cancer. Induction of cancer cell death and inhibition of survival are the main principles of cancer therapy. In this context, autophagy may have dual roles in cancer, acting on the one hand as a tumor suppressor and on the other as a mechanism of cell survival that can promote the growth of established tumors. Therefore, understanding the role of autophagy in cancer treatment is critical. Moreover, defects in apoptosis, programmed cell death, may lead to increased resistance to chemotherapy. Purpose: The aim of the present study was to detect BRCA1 gene mutations in order to throw more light on their roles as risk factors for breast cancer in Egypt. Secondly the role of autophagy and apoptosis in determining response to a fluorouracil, doxorubicin, cyclophosphamide (FAC) regimen was investigated. Materials and Methods: Forty-five female breast cancer cases and thirty apparently healthy females were enrolled in the present study. Serum levels of autophagic biomarkers, Beclin 1 and LC3 as well as the serum levels of apoptosis biomarkers Bcl-2 and Caspase-3 were measured before and after chemotherapy. Results: BRCA1 mutations were found in 5 (16.7%) and 44 (99.8%) of the controls and cancer patients, the most frequent being 5382insC followed by C61G and 185 delAG. The results revealed that chemotherapy caused elevation in serum concentration levels of the autophagic biomarkers (Beclin 1 and LC3). This elevation was associated with a significant decrease in serum concentration levels of Bcl-2 and significant increase in caspase-3 concentration levels (apoptotic markers). Conclusions: The results of the present study indicate a very high level of BRCA mutations in breast cancer cases in Egypt and point to involvement of autophagic and apoptotic machinery activation in response to FAC chemotherapy.

• Korean Journal of Social Welfare
• /
• v.44
• /
• pp.146-177
• /
• 2001

One of the difficulties of female-headed families face is economic hardship. Low-income single mothers work long hours, become isolated and feel burdened for dual roles. And many of them don't have relatives to share parenting roles. As a result, children of low-income female-headed families are easy to be neglected and left to form a delinquency-prone group in neighborhood. Traditionally, it has been viewed that children in female-headed families have problems due to the loss of father role. However, study indicates that these children can adjust well if the relationship between mothers and children is consistent and adequate. An Intervention program for low-income female-headed elementary children was developed and delivered in two community social welfare centers. The purpose of the program is to raise self-esteem. Two goals were 1) management of daily living habits and 2) improvement of family relations. Social workers maintained contact with mothers to talk about children's behaviors and to prompt hugging and touching. In addition, workers helped children to form good relationships with peers and school teachers. Children were satisfied with the program. Their family relations were improved statistically significantly after the program(wilcoxon signed rant test z=-2.934 p<.05). However, their self esteem were not improved significantly (wilcoxon signed test z=-1.173 p>.05). Qualitative analysis of each children were also discussed. The implications of the study are the followings: Intervention programs need to be delivered separately for low-grade and high grade elementary children because they have different developmental needs. The program also need to include education on sex and marriage as well as aggression reduction. Society needs to provide more support to single mothers for their personal and parenting needs.