• Title/Summary/Keyword: drug-resistant trichomonas

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Antitrichomonas Activity of Herb-medicine Generally Used in Dong-Eui-Bo-Kham (동의보감의 한약재에 대한 항질편모충 효능에 대한 연구)

  • Park, Chung-Un;Lee, Geon-Mok;Kim, Youn-Chul;Ryu, Jae-Sook;Kim, Tae-Kyun;Kim, Jong-Ho;Kim, Min-Kyeoung;Song, Ho-Cheol;Park, Hyun
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.1
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    • pp.191-195
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    • 2005
  • Eighteen aqueous and two ethanol extracts of herb-medicine used for trichomoniasis therapies in Korea were assessed for their antitrichomonas activities. Two extracts(Sophorae radix, Phellodendri cortex) showed evident antitrichomonas activity at $8mg/m{\ell}$. Two mixture of Sophorae radix and Phellodendri cortex showed low antitrichomonas activity at 15mg/ml. Ethylacetate fraction of Sophorae radix showed the antitrichomonas activity of 400 mg/ml. This indicated that Sophorae radix is potent for a new effective and safe antitrichomonas agent.