• 제목/요약/키워드: dream

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Current status of CRISPR/Cas9 base editor technologies and their applications in crop precision breeding

  • Kim, Rigyeong;Song, Jaeeun;Ga, Eunji;Min, Myung Ki;Lee, Jong-Yeol;Lim, Sun-Hyung;Kim, Beom-Gi
    • 농업과학연구
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    • 제46권4호
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    • pp.885-895
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    • 2019
  • Plant biotechnologists have long dreamed of technologies to manipulate genes in plants at will. This dream has come true partly through the clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 technology, which now has been used to edit genes in several important crops. However, there are many restrictions in editing a gene precisely using the CRISPR/Cas9 technology because CRISPR/Cas9 may cause deletions or additions in some regions of the target gene. Several other technologies have been developed for gene targeting and precision editing. Among these, base editors might be the most practically and efficiently used compared to others. Base editors are tools which are able to cause a transition from cytosine into thymine, or from adenine into guanine very precisely on specific sequences. Cytosine base editors basically consist of nCas9, cytosine deaminase, and uracil DNA glycosylase inhibitor (UGI). Adenine base editors consist of nCas9 and adenine deaminase. These were first developed for human cells and have since also been applied successfully to crops. Base editors have been successfully applied for productivity improvement, fortification and herbicide resistance of crops. Thus, base editor technologies start to open a new era for precision gene editing or breeding in crops and might result in revolutionary changes in crop breeding and biotechnology.

우주발사체 개발의 국내외 동향 (Trend of Domestic and International Development of Space Launch Vehicles)

  • 공현철;이준호;오범석
    • 항공우주산업기술동향
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    • 제6권2호
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    • pp.109-115
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    • 2008
  • 대한민국 전라남도 고흥군 외나로도에 위치한 나로우주센터에서 2009년 상반기에 대한민국이 그렇게도 고대하던 위성자력발사의 쾌거가 발생하게 된다. 소형위성 발사체(KSLV-I)는 그동안 대한민국에서 과학로켓 시리즈의 개발을 통해서 축적한 기술과 노하우를 활용하여 우주발사체 개발로서 승화한 작품으로써 질량 100kg의 과학 위성2호를 싣고 발사하여 온 국민에게 희망과 꿈을 선사하게 될 것이다. 국제적으로는 미국 및 러시아의 우주개발 활동에 이어 일본의 가구야 달 탐사선, 중국의 창어 달 탐사선 및 우주유영 그리고 인도의 달 탐사선 찬드라얀 1호의 발사 등 제2의 우주개발 경쟁이 일어나고 있다. 이러한 국내외의 상황을 고려하여 국내외의 우주발사체 개발 동향을 정리하는 것이 본 논문의 목적이다.

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임상실습에 대한 간호학생의 태도 : Q 방법론 적용 (Attitudes of Nursing Students to Clinical Education : Q methodological Approach)

  • 박송자
    • 대한간호학회지
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    • 제23권4호
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    • pp.544-554
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    • 1993
  • The study was designed to identify the attitude of nursing students to clinical education through Q-methodology. A C sample was developed through a review of the literature and interviews. Twenty - seven statements made up the finalized Q- sample. This was out of an initial 143 statements developed through consultation with eight professors. The P sample consisted of 25 nursing students in S Health Junior College.0 statements were written on seperate cards and were given to the 25 subjects to sort according to degree of agreement or disagreement. The Q-sorts by each subject were coded and analyzed with QUANL PC Program. The analysis discovered three major attitudes, namely “amicable adaptation” 〈type 1), “Nightingale social service” (type 2), and “realistic occupation pursuit” (type 3). The correlation was .465 between type 1 and type 2, .293 between type 1 and type 3, and .273 between type 2 and type 3. The characteristics of each type were as follows ; Type 1 (amicable adaptation) They satisfied in interpersonal relationships in the clinical setting. They would not dream of becoming Nightingale, but thought of nursing care affirmatively and performed their works faithfully and adapted themselves to the new circumstances easily, Fourteen subjects were classified as type 1. Type 2 (Nightingale: social service) They often dreamed as a child that they would be Nightingale with a white uniform and think that nursing is a gift from heaven. They have an aptitude for nursing care by nature and selected nursing science them-selves. They give care to the sick with pleasure. Seven subjects were classified as type 2. Type 3 (realistic occupation pursuit) They were not satisfied with their nursing practice. First of all they want a stable job, therefore they selected nursing science. They had conflicts in clinical practice, but were responsible for nursing and studied hard. Four subjects were classified as type 3. Through the results of this study, the attitude of nursing students to clinical education could be classified into three types. Therefore it is suggested that clinical education would be more valuable, if it was planned according to an understanding of the attitudes of nursing students to clinical education.

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진로 교육 방안 모색: 분야 최고 전문가의 꿈은 어떻게 이루어지는가? (An Investigation of a Way of Career Education: How is the Dream of the Best Field Experts Achieved?)

  • 송광한
    • 한국융합학회논문지
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    • 제9권1호
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    • pp.405-418
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    • 2018
  • 본 논문은 자유학기제 진로탐색을 위한 기초 자료 제공의 차원에서 시행되었다. 진로교육의 목적을 전문가 양성에 두고 전문가 수행 요건에 대한 선행 연구 결과들을 기초로 진로탐색을 위한 구체적인 접근 방법을 도출하려 하였으나 전문가 수행 요건에 대한 논쟁들이 해결이 되지 않고 있는 상황이어서 전문성 핵심 요소들을 인간의 다양한 인지 현상들이 형성되어 나오는 근원적 인지 메커니즘을 통해 전체적으로 확인하였다. 그 결과 전문가 영역은 내용 전문성과 표현 전문성으로 구분되는데 내용과 표현이 다양한 통합 비율로 결합되어 있는 전문성과 내용이나 표현이 독립적으로 구성된 전문성으로 다시 다양하게 구분되며, 각 영역에 따라 전문가 수행에 요구되는 조건들이 다양하다. 한편 분야 최고 전문가는 지능, 내적사고, 호기심, 집착력 등의 수준이 특정 전문성이 요구하는 수준과 일치될 때 탄생할 수 있고, 특히 집착력이 결정적 역할을 하는 것으로 나타났다. 본 논문은 이런 결과를 바탕으로 전문성과 관련된 쟁점들에 대해 논의하고 자유학기제 진로 탐색을 위한 구체적인 접근법을 제공하고 있다.

현대복식에 반영된 오리엔탈리즘의 기호학적 분석 (A Semiotic Analysis of Orientalism Reflected in Modern Clothing)

  • 이춘희;신상옥
    • 복식
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    • 제50권4호
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    • pp.131-146
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    • 2000
  • The starting point of this study was that the Orientalism reflected in the modern clothing is realized the different view by Western and Eastern. Based on this regard, this study semiotically analyse that clothing is creating the cultural values and signification and that the western designers are reproducing an ideology as orientalism being the western-oriented thought when expressing the Asian image in the modern clothing. The theoretical sides are based on the semiotic analyses of F. Saussure, C. Peirce, and R. Barthes. By the result observed through this study, the Orientalism reflected in the modern clothing designed by Western designers are discriminative image, mystic image, past-oriented image, natural image, and complex-eclectic image. The discriminative image is reproduced as a savage and uncivilized image. In addition, it regarded as a decorative and superficial image is expressed as if it is an uncharacterized and underdeveloped image in the modern clothing. The mystic image is reproduced as a romantic image to stimulate Westerners'curiosity. That is, Asian image is regarded as a dream and magical image rather than a scientific and rational image. The past-oriented image is expressed through restricting Asian positive image in Asian historical glory. The natural image differs from Western image based on science in the modern clothing. The modern clothing regards the natural image as a primitive and instinctive image. The complex-eclectic image is the pastish pattern through selecting and distributing heterogeneous materials in the modern clothing. This study critically analyzes the western-oriented thought of orientalism in the modern clothing. The results of the study imply that it is critical that we provide a new contact point for the East and the West in the context of our Asian values and traditions.

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하이패션에 나타난 패션구두의 조형성 (A Study on the Formativeness of the Fashion Shoes in High Fashion)

  • 이효진
    • 복식
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    • 제59권9호
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    • pp.55-70
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    • 2009
  • This study aims at analyzing the formativeness of women fashion shoes shown in the high fashion since 2000 along with the necessity of study for such purposes. Fashion shoes designed for the perfection of high fashion have been positioned as an important item to increase the value of fashion. Subsequently, three formative images through the research method under the literature study could be analyzed as follows. First, the Fetishism image appeared from 18th century and the shoe heel has the erotic internal beauty while attracting the erotic nature from the perspective of 'feet confinement'. The high heel came to have an absolute relationship with the feminine beauty, and the feet and shoes are accepted for the erotic symbol regardless of anyone in the East or West. Second, the fashion shoes in the Maximalism image to pursue for the dream and excitement at the same time have been shown at the same time by using various ornaments in an exaggerated manner for the use of ornaments to clothes through designs by shoe designers. Third, the Aristocratism image in the fashion shoes was remarkably highlighted with the use of materials from processing natural materials with the best quality, which was expressed in an exotic manner with roughness and comfort despite the nature of refinement balanced with the simple reactionary tendency and technical senses of handicrafts. It can be perceived that the inner emotions of human beings are expressed by intentionally dismantling the functions of shoes in terms of functionality even in the fashion shoes in completing the ideal images after which are pursued by people.

웨어러블 디바이스의 검색, 참여, 공유, 분석을 통한 인문학적 메타포 도출 (Deduction of Humanistic Metaphor based on Searching, Participation, Sharing and Analysis of Wearable Device)

  • 이원태;강장묵
    • 한국인터넷방송통신학회논문지
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    • 제14권3호
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    • pp.125-130
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    • 2014
  • 구글 글라스가 출시됨에 따라 웨어러블 컴퓨터 또는 웨어러블 디바이스에 대한 관심이 높아지고 있다. 이 글은 웨어러블 컴퓨터의 개발과 활용에 인문학적 메타포를 어떻게 적용할지에 대한 탐색적(exploratory) 연구이다. 인문학은 인간 내면의 꿈, 상상, 욕망을 실체로 한다. 반면 공학에서 다루는 소프트웨어 개발방법론이나 애플리케이션 설계는 논리적 언어로 표현된 검증 가능한 대상이다. 이 글은 상이한 두 학문을 인간친화적 애플리케이션 개발을 위해 융합시키려는 시도로서 '구조혈'이라는 인문사회과학적 개념을 매개로 인문학적 메타포를 적용한 웨어러블 컴퓨터의 설계와 서비스 시나리오를 도출하고자 하였다. 구체적으로 웨어러블 컴퓨터에서 정보를 검색하고 공유하고 참여하고 분석하는 서비스의 사례와 이 과정에 적용 가능한 인문학적 메타포가 무엇인지를 밝혔다.

호스피스 환자의 임종증상

  • 최화숙;김수지
    • 호스피스학술지
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    • 제2권1호
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    • pp.75-86
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    • 2002
  • Prupose: The purpose of this study was to identify signs and symptoms of hospice patients during their dying processes. Method: The subjects of this study were 76 patients who received hospice care services in 2 different hospice care programs in Seoul area. Data was obtained from January, 1999 to June, 2001 by hospice nurse's observation, interviews with patient's primary caregiver and hospice volunteers, patient's self report, nursing records and questionnaires which had been developed by selecting from various references and refining them based on the result of preliminay studies. The collected data were analyzed with the SPSS PC+ program and content analysis. Results: Mean lengths of hospice patient's dying process were 3.6 days. Physical signs and symptoms of hospice patients during their dying processes were 'increased sleep'(89.5%), 'decreased oral intake of food'(88.2%) and 'liquids'(86.8%), 'change of respiration'(82.9%), 'decreased urine output'(80.3%), 'cold extremities'(69.7%), 'death rattle'(67.1%), 'cyanosis'(57.9%), 'restlessness'(55.3%), etc. And psychological, spiritual and social signs and symptoms were 'decreased interpersonal relationships'(61.8%), 'panorama of memories from childhood'(60.5%), 'experiences as like hallucination'(56.5%), 'saying bye with family'(69.7%), 'forgiveness', 'make a will', etc. Experiences as like hallucination were seemed not as dream but reality were shown by 43 dying patients. They had experienced to see and to talk with their deceased mother(18.6%) and/or relatives(30.2%), angels(20.9%), heaven(11.6%), old house in which they had lived, someone from the world beyond with black clothes, etc. Conclusion: The above results indicate that death of hospice patients is ongoing process with dying signs and symptoms during several days contains not only in physical aspects but also among psychological, spiritual and social aspects including family dynamics.

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만성 뇌졸중 환자의 균형 및 보행 증진을 위한 체간 자가 훈련 프로그램 -예비연구- (Self-Training Trunk Program for Improving Balance and Walking Ability in People with Chronic Stroke -A Preliminary Study-)

  • 나은진;우영근
    • PNF and Movement
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    • 제15권3호
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    • pp.317-331
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    • 2017
  • Purpose: Balance and walking ability are important elements of functional independence for people with stroke and are major goals in rehabilitation. These abilities require trunk performance, but most chronic stroke patients reach a plateau in their rehabilitation. Therefore, the purpose of this study was to investigate the effects of a self-training trunk program to improve balance and walking ability in people with stroke, and to suggest such a self-training program for integrated rehabilitation of people with stroke. Methods: The study recruited 7 people with stroke. The subjects performed trunk training for 30 min per day, 6 days per week, for 3 weeks. Participants were measured on the Trunk Impairment Scale (TIS), the Berg Balance Scale (BBS), the Korean Activities-specific Balance Confidence (K-ABC) scale, the Falls Efficacy Scale (FES), the Functional Gait Assessment (FGA), the 6 Minute Walk Test (6MWT) and a gait analysis to measure the training effects. Statistical analysis used the Wilcoxon signed-rank test as a non-parametric statistical test. Results: TIS was not significantly different after the self-training trunk program, but BBS (p>0.05), K-ABC, and FES were significantly improved after the training program (p<0.05). Furthermore, the 6MWT, stride/height %, and one-leg stance were significantly improved after the training program (p<0.05), but cadence, stance, and swing duration were not significantly different after the training (p>0.05). Conclusion: These results suggest that a self-training trunk program should be integrated into stroke rehabilitation to improve balance and walking ability, and further research is needed to develop the program to be more effective for chronic stroke patients.

생태미학적 관점에서의 지속가능한 흙건축 특성에 관한 연구 - 노자사상을 중심으로 - (A Study on Sustainable Earth Architecture Characteristic from Ecological Aesthetic Point of View - Focus on the thoughts of Lao-tzu -)

  • 김설희;허범팔
    • 한국실내디자인학회논문집
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    • 제20권4호
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    • pp.54-62
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    • 2011
  • Fast industrialization caused from Descartes' dichotomy has enormously developed our world, but endangered the ecosystem. In this study, the ecosystem aesthetics is not only a critique against existing growth-ideology and technical civilization, but also the art pursuing the life as an artistic state and achieving the dream for qualitatively different new future. Lao-tzu's Natural Beauty assumes that the adaptation to natural laws can lead every purpose's achievement. Based on such theoretical alternative, the earth construction as a medium for coexisting mankind, nature and construction interacts with the other objects through the natural affinity, the energy efficiency, the material generation. The earth construction provides the images of naivety, naturalness, folk as well as emotional stability in cultural terms. This study's direction and method are as follows. First, it researches the ecosystem aesthetics from the Taoism viewpoint, the alternative for environmental healing based on theoretical reviews about the ecosystem aesthetics. Second, it researches the earth construction's ecosystem aesthetic features and construction features from the low-tech aspect in continual construction genealogy. Third, it analyzes some cases targeting domestic buildings by drawing out expression methods and features through the connectivity of earth construction and ecosystem aesthetics. The earth construction lies between the heaven and the earth, but coexists in natural cycle. The earth construction caused from ecosystem aesthetics will be a future alterative, and various studies about its features and methods should be continued.