• 제목/요약/키워드: downstream processing

검색결과 102건 처리시간 0.031초

폴리곤 기반 역공학 시스템의 후처리 기능에 관한 연구 (A study on the post-processing functions in a polygon-based reverse engineering system)

  • 박진표;박광현;최영;전용태;노형민
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2001년도 춘계학술대회 논문집
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    • pp.41-44
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    • 2001
  • In reverse engineering, the whole surfaces of the three-dimensional(3D) product are measured using 3D positional scanners. The raw triangle meshes constructed from a scanned point set are not well suited for direct use in the downstream activities. This is because the amount of triangle meshes may be very large(from millions to hundreds of millions) and usually distorted by scanning error. Furthermore, the triangle meshes may contain several holes that must be filled. Thus, several solutions have to be addressed and implemented before a complete CAD models can be acquired. This paper discusses on the algorithms of decimation, smoothing, and hole-filling that are crucial to refine the triangle meshes. Several examples are also given and discussed to validate the system.

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생쥐 복수로부터의 단세포군 항체분리를 위한 크로마토그라피 분리정제 방법의 개발 Part II. 히드록실아파타이트 크로마토그라피 단일 단계만의 사용 (Development of Chromatographic Downstream Processing for the Purification of Monoclonal Antibody from Ascites Fluid: Part II Use of Single Hydroxylapatite Chromatographic Step)

  • Ahn, I.S.;Park, C.Y.
    • 한국미생물·생명공학회지
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    • 제17권3호
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    • pp.269-272
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    • 1989
  • In order to obtain monoclonal antibody from ascites fluid at sufficiently high purity using a single hydroxylapatite chromatography (HA) a further optimization on its operating variables was carried out. By adjusting the pH of the eluent, the sodium phosphate buffer, to 6.0 from 6.8 and adding CaCl$_2$to 1 mM at the column inlet, the elution molarities (M$_{elu}$) for the desired monoclonal antibody and contaminating proteins can be distinguished from each other with enough resolution. Previously these two groups of proteins co-eluted at the same time at pH 6.8 and without CaCl$_2$. This sin81e step hydroxylapatite chromatography yields the desired antibody pure enough for diagnostic use.

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가솔린 엔진용 분사노즐의 간헐적인 분무특성 (Intermittent Spray Characteristics of the Injection Nozzle for a Gasoline Engine)

  • 김원태;오제하;강신재;노병준
    • 한국자동차공학회논문집
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    • 제5권3호
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    • pp.128-136
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    • 1997
  • Spray characteristics of a fuel injector have an important effect upon engine power and emission. Thus this study was investigated the spray characteristics of the intermittent injection using a gasoline fuel injector. Image processing system and PDA system were utilized for visualization of a spray behavior and measurements of a droplet size and velocity, respectively. Fuel injection duration was fixed with 3ms and injection pressure was varied such as 250kPa, 300kPa, 350kPa. for a high fuel injection pressure, spray tip arrival time was fluctuated at a vigorously disintegrated cross section. Axial velocity was linear correlated with fuel droplet size in the time interval of an injected main spray at spray downstream.

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흡기관 내의 혼합기 유동 특성에 관한 연구 (A Study on the Flow Characteristics of the Mixture in an Intake Manifold)

  • 이창식;조병옥
    • 한국자동차공학회논문집
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    • 제4권1호
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    • pp.218-228
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    • 1996
  • The behaviors of the mixture at the downstream of throttle valve in a TBI type gasoline engine plays a greater role in design of intake system. A good mixture has been influencing directly not only on the engine power but also on the pollutant emission. The mixture flow in an intake manifold is very complex, and the flow characteristics are varied with the valve type, valve angle, inlet air flow rate, and the other flow factors. Three kinds of valve are chosen in this study, and the informations of the mixture flow are observed experimentally using a PIV apparatus. Perforate valve has a smaller recirculation zone than the case of solid valve with a lower valve loss coefficient, and iti is verified that the perforated valve is also suitable to control the flow rate in a mixture flow system.

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효율적 Cyclinc Extension을 갖는 Zipperqkdtlr의 VDSL 모뎀 (A Zipper-based VDSL Modem with an Efficient Cyclic Extension)

  • 위정욱
    • 한국통신학회논문지
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    • 제25권10B호
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    • pp.1793-1802
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    • 2000
  • In this paper we propose an efficient implementation technique for cyclic extension in VDSL(Very High bit-rate Digital Subscriber Line) systems using Zipper duplexing and analyze its performances under typical telephone channel environments. In Zipper-based VDSL systems each DTM(discrete-multitone) block is appended by both cyclic prefix(CP) and cyclic suffix(CS). The CP is inserte to prevent both intersymbol interference (ISI) and iterchannel interference (ICI) while the CS is appended to ensure orthogonality between the upstream and downstream carriers thus preventing near-end crosstalk (NEXT). However in order to implement the CP in the transmitter side of the VDSL system an additional hardware is required to append the latter part of each DMT symbol to the beginning of the DMT symbol. In this paper we propose a VDSL system with Zipper duplexing using only CS to reduce hardware complexity (memory and processing delay) required for implementation of CP. It is shown by computer simulation that the proposed approach has the same capacity under typical channel environments as the previous Zipper-based VDSL system using both CP and CS. even with a significantly lower hardware complexity.

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생물공학에서의 합성막 : 현실과 가능성 (Synthetic Membranes in Biotechnology: Realities and Possibilities)

  • Belfort, Georges
    • 멤브레인
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    • 제2권2호
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    • pp.91-103
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    • 1992
  • Synthetic membrane processes are being increasingly integrated into existing reaction, isolation, and recovery schemes for the production of valuable biological molecules. In many cases they are replacing traditional unit processes. The properties of membrane systems which are most often exploited for both upstream and downstream processing and their permselectivity, high surface area per unit volume, are their potential for controlling the level of contact and/or mixing between two separate phases. Advances in both membrane materials and module design and operation have led to better control of concentration polarization and membrane fouling. After presenting some recent advances in membrane materials and fluid mechanics, we demonstrate how membranes have been integrated into cellular and enzymatic reaction schemes. This is followed by a review of established and emerging synergism between biological processes and synthetic membranes.

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Synthetic membranes in Biotechnology: Realities and Possibilities

  • Belfort, Georges
    • 한국막학회:학술대회논문집
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    • 한국막학회 1992년도 추계 총회 및 학술발표회
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    • pp.15-33
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    • 1992
  • Synthetic membrane processes are being increasingly integrated into existing reaction, isolation, and recovery schemes for the production of valuable biological molecules. In many cases they are replacing traditional unit processes. The properties of membrane systems which are most often exploited for both upstream and downstream processing are their permselectivity, high surface area per unit volume, and their potential for controlling the level of contact and/or mixing between two separate phases. Advances in both membrane materials and module design and operation have led to better control of concentration polarization and membrane fouling. After presenting some recent advances in membrane materials and fluid mechanics, we demonstrate how membranes have been integrated into cellular and enzymatic reaction schemes. This is followed by a review of established and emerging membrane separation processes. Several examples are used to emphasize the synergism between biological processes and synthetic membranes.

박판성형해석을 위한 자동 프리에지 제거에 관한 연구 (A Study on the Automatic Elimination of Free Edge for Sheet Metal Forming Analysis)

  • 유동진
    • 소성∙가공
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    • 제13권7호
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    • pp.614-622
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    • 2004
  • A new approach for the automatic elimination of free edges in the finite element model for the analysis of sheet metal forming processes is presented. In general, the raw finite element model constructed from an automatic mesh generator is not well suited for the direct use in the downstream forming analysis due to the many free edges which requires tedious time consuming interactive graphic operations of the users. In the present study, a general method for the automatic elimination of free edges is proposed by introducing a CAD/CAE hybrid method. In the method a trimmed parametric surface is generated to fill the holes which are orginated from the free edges by using the one step elastic finite element analysis. In addition, mesh generation algorithm is suggested which can be used in the general trimmed surface. In order to verify the validity of the proposed method, various examples including actual automobile sheet metal parts are given and discussed.

한국어 ELECTRA 모델을 이용한 자연어처리 다운스트림 태스크 (Korean ELECTRA for Natural Language Processing Downstream Tasks)

  • 황태선;김정욱;이새벽
    • 한국정보과학회 언어공학연구회:학술대회논문집(한글 및 한국어 정보처리)
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    • 한국정보과학회언어공학연구회 2020년도 제32회 한글 및 한국어 정보처리 학술대회
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    • pp.257-260
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    • 2020
  • 사전 학습을 기반으로 하는 BERT계열의 모델들이 다양한 언어 및 자연어 처리 태스크들에서 뛰어난 성능을 보이고 있지만, masked language model의 경우 입력 문장의 15%만 마스킹을 함으로써 학습 효율이 떨어지고 미세 조정 시 마스킹 토큰이 등장하지 않는 불일치 문제도 존재한다. 이러한 문제를 효과적으로 해결한 ELECTRA는 영어 벤치마크에서 기존의 언어모델들 보다 뛰어난 성능을 보여주었지만 한국어에 대한 관련 연구는 부족한 실정이다. 본 연구에서는 ELECTRA를 한국어 코퍼스에 대해 학습시키고, 다양한 한국어 자연어 이해 태스크들에 대해 실험을 진행한다. 실험을 통해 ELECTRA의 모델 크기별 성능 평가를 진행하였고, 여러 한국어 태스크들에 대해서 평가함으로써 ELECTRA 모델이 기존의 언어 모델들보다 좋은 성능을 보인다는 것을 입증하였다.

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클로렐라 시스템에서 항균펩타이드 Magainin 2의 효율적인 세포외 분비 (Efficient Extracellular Secretion of the Antimicrobial Peptide Magainin 2 in the Chlorella-based System)

  • 정유정;황재윤;김성천
    • 한국해양바이오학회지
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    • 제16권1호
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    • pp.55-62
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    • 2024
  • Various antimicrobial peptides (AMPs) from microalgae have shown antibacterial, antiviral, antifungal, anticancer, and antioxidant effects, and play crucial roles in medical applications, aquaculture-related disease management, and the food industry. Magainin 2 (MAG2), an AMP, exhibits high antibacterial and antitumor activity, necessitating an efficient recombinant expression system for low-cost, large-scale production. To enhance MAG2 secretion efficiency in Chlorella, we constructed the SS:MAG2:His vector using the known Chlamydomonas reinhardtii CA1 signal sequence (SS) and obtained a stable transformant via an Agrobacterium-mediated transformation method and RT-qPCR. ELISA results revealed that the MAG2 content secreted into the medium by the SS:MAG2:His transformants increased proportionally with mRNA expression. These findings offer a strategy for high MAG2 secretion in the Chlorella vulgaris platform, potentially minimizing downstream processing costs.