• Journal of Dental Anesthesia and Pain Medicine
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• v.15 no.3
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• pp.181-184
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• 2015

Airway difficulties are a major concern for anesthesiologists. Even though fiberoptic intubation is the generally accepted method for management of difficult airways, it is not without disadvantages-requires patient cooperation, and cannot be performed on soiled airway or upper airways with pre-existing narrowing pathology. Additionally, fiberoptic bronchoscopy is not available at every medical institution. In this case, we encountered difficult airway management in a 71-year-old man with a high Mallampati grade and a thick neck who had undergone urologic surgery. Several attempts, including a bronchoscope-guided intubation, were unsuccessful. Finally, blind nasal intubation was successful while the patient's neck was flexed and the tracheal cartilage was gently pressed down. We suggest that blind nasal intubation is a helpful alternative in difficult airway management and it can be a lifesaving technique in emergencies. Additionally, its simplicity makes it a less expensive option when advanced airway technology (fiberoptic bronchoscopy) is unavailable.

• BMB Reports
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• v.45 no.9
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• pp.515-520
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• 2012

High expression of osmotically responsive genes1 (HOS1), a key regulator of low temperature response and flowering time, encodes an E3 ubiquitin ligase in Arabidopsis. Here, we report characterization of a newly identified splice variant (HOS1-L) of HOS1. Comparative analyses revealed that HOS1-L has a longer 5' nucleotide sequence than that of the previously identified HOS1 (HOS1-S) and that its protein sequence was more conserved than that of HOS1-S in plants. HOS1-L transcripts were spatio-temporally more abundant than those of HOS1-S. The recovery rate of HOS1-S expression was faster than that of HOS1-L after cold treatment. Diurnal oscillation patterns of HOS1-L revealed that HOS1-L expression was affected by photoperiod. An in vitro pull-down assay revealed that the HOS1-L protein interacted with the ICE1 protein. HOS1-L overexpression caused delayed flowering in wild-type plants. Collectively, these results suggest regulation of HOS1 expression at the post-transcriptional level.

• Journal of Korean Society of Water and Wastewater
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• v.11 no.2
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• pp.40-49
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• 1997

From water management point of view, the industrialization that we have achieved in the last decades brought out two major changes: water shortage and water quality deterioration. They are getting the big obstacles we must overcome to continuously pursue industrialization for further development in the next century. Many plans using dams and advanced treatment methods have been developed for control of quantity and quality, respectively. In this paper, an alternative is conceptually reviewed which is much different from the plans in regard that the alternative looks at system itself. It is based on an interceptor system coupling with a concept of zero-discharge. This system allows no discharge of wastewaters from point-sources to waterbodies which are very sensitive in terms of water quality. In addition reuse of treated effluents is emphasized to a maximum extent. The application of the system to the Nak-Dong river basin indicated that an interceptor system will need from the middle reaches of the basin where industrialization gets heavier. Since wastewaters are not directly discharged to the river, water quality of the down stream will improve. Treated effluents will be able to be reused at a number of industrial complex which currently get water from the Nak-Dong river. This reuse will help alleviate water shortage. The biggest problem anticipated is cost for building and operating such system. A cost-sharing plan among the beneficiaries is considered. Further research is suggested focusing on detailed engineering and technical matters for potential implementation.

• Journal of the Economic Geographical Society of Korea
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• v.15 no.4
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• pp.464-480
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• 2012

This paper includes consideration for construction of Sejong City and seeking its alternative. Korean government has gone ahead with the relocation of 35 ministries of central government from Seoul metropolitan area to Sejong city for balanced regional development. But many specialists are worried about the spatial division of government function because such a spatial division would bring down the functional efficiency of central government. This paper proposes to make Sejong city the administrative capital city instead of the relocation of some ministries to Sejong city, and discusses the necessity and appropriateness to develop Sejong city as an administrative capital city.

• Preventive Nutrition and Food Science
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• v.10 no.3
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• pp.298-309
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• 2005

As the population of the elderly grows, the prevalence of osteoporosis and its related fractures will increase in both men and women. The etiology, preventive and curative strategies of male osteoporosis are relatively unknown and understudied in comparison with those of female osteoporosis. Even currently approved therapies, e.g. bisphophonates, parathyroid hormone, and testosterone for male osteoporosis are in need of further investigation to test their safety and efficacy. Isoflavones which are found in soy have been shown to positively affect bone by stimulating bone formation while concurrently slowing down bone resorption. These observations mainly come from studies that have employed women or female animal models of osteoporosis. Therefore, there is a need to explore the role of soy and its isoflavones in preventing bone loss or rebuilding bone utilizing men or animal models of .male osteoporosis. From the review of existing literature it is too early to state the extent to which men with osteoporosis can benefit from consumption of soy or its isoflavones. In this review, the efficacy of soy and its isoflavones as alternative and/or adjunctive treatment for male osteoporosis will be discussed.

• Journal of Korea Society of Digital Industry and Information Management
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• v.8 no.4
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• pp.193-203
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• 2012

This study analyzed regular transportation costs between port warehouses and processing plants and between processing plants and central distribution centers and further transportation costs relations according to empty transfer rates in each circulation by examining the distribution routes of imported grain including wheat, barley, corn, and soybean, namely port warehouses, processing plants, and central distribution centers. Based on the results, the study compared and reviewed the logistics transportation costs. The analysis results of the alternative model show that logistics operational costs could be considerably cut down by introducing a flexible vehicle transportation operational method, which is to change the vehicle loading parts for proper substitute transportation after unloading and transport them to other locations such as central distribution centers instead of returning empty, as an alternative to high operational costs deriving from empty vehicle operation in each circulation after unloading items in case of transportation of imported grain and processed items. The results allow for a more realistic approach to general problems with large-scale distribution network operation and provide a theoretical foundation to serve as a guide to establish policies for corporate operation of imported grain logistics systems.

• Korean Journal of Human Ecology
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• v.20 no.6
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• pp.1229-1237
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• 2011

The objective of this study was to evaluate the quality characteristics of Cheongpomook prepared with five different levels of mungbean powder (0, 25, 50, 75, and 100%). We conducted the Hunter's color values, the rheological characteristics, sensory evaluations, and pasting properties of the Cheongpomook samples. The more mungbean powder was added, the more the luminance and Hunter's a values of Cheongpomook samples were decreased, but in Hunter's a values was reverse. With regard to the rheological properties of the Cheongpomook samples, the more mungbean powder was added, the values of hardness, springiness, gumminess, and chewiness were significantly decreased. In color, taste, and overall quality, the value of 25% mungbean powder added Cheongpomook (MP1) and 50% added Cheongpomook (MP2) were significantly higher than those of others. The resulting RVA viscogram, peak viscosity, hold viscosity, break down, setback, and final viscosity of Cheongpomook were decreased with an increase in mungbean powder, but the pasting temperature was increased slightly. Therefore, an addition of 25% mungbean powder appears to be an acceptable approach to enhance the quality of Cheongpomook without reducing acceptability.

• Journal of the Korea Society of Computer and Information
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• v.21 no.11
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• pp.141-149
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• 2016

In a rapidly changing global environment and the massive development in IT technology, Manufacturing SMEs have difficulties in lack of resources and competencies continued to have strong growth potential "Korean Hidden Champion(K Champ)". In order to overcome the difficulties of Manufacturing SMEs, we examined the core competencies using the AHP and proposed the K Champ development strategy. The implications in the academic is as follows: First, the suggestions for development strategy plan was drawn for the K Champ's core competencies with the recognized importance by the CEO or business executives. Secondly, the manufacturing SMEs were broken down by industry structural characteristics variables(sales amounts, industry sectors, business types and delivery methods) and the importance was investigated, analyzed and clarified. This study is intended to develop strategies of Gyeongsangnam-do manufacturing SMEs for K Champ such as German 'Hidden Champion'. We identified the importance of the level of core competencies and the coherent alternative policy direction and practical alternative were proposed. These mean the concrete relationship of core competencies for the K Champ transition and suggest a realistic directional needed for the local manufacturing SMEs in the proposed 'Government's Development Policy for Korean Hidden Champion'.

• International Journal of Highway Engineering
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• v.19 no.3
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• pp.19-30
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• 2017

PURPOSES : This study proposes the road asset valuation approach using alternative depreciation methods. It has become necessary to have asset management system according to the adoption of accrual basis accounting for governmental financial reporting and the amendment of the road act. Therefore, it is very important to analyze the effect of depreciation methods on road asset value as a basic research for road asset management system. METHODS : The Ministry of Strategy and Finance (MOSF) has mainly performed road asset valuation based on Write down Replacement Cost and Straight Line depreciation method. This study suggests some appropriate asset valuation methods for road assets through case analysis using three depreciation methods: Consumption-based depreciation method, Condition-based depreciation method, and Straight Line depreciation method. A road asset valuation data of national highway route 1 (year 2014) is used to analyze the effect of three depreciation methods on the road asset value. Road assets include land and structures (pavement, bridge, and tunnel). This study mainly focuses on structures such as bridges and tunnels, because according to governmental accounting standards, land and road pavement assets do not depreciate. RESULTS : The main results of this study are as follows. Firstly, overall asset value of national highway route 1 was estimated at 6.97 trillion KRW when MOSF's method (straight-line depreciation method) is applied. Secondly, asset value was estimated at 4.85 trillion KRW on application of consumption-based depreciation method. Thirdly, asset value was estimated at 4.37 trillion KRW when condition-based depreciation method is applied. Therefore, either consumption-based or condition-based depreciation methods would be more appropriate than straight-line depreciation method if we can use the condition data of road assets including land that are available in real time. CONCLUSIONS : Since road assets such as pavements, bridges, and tunnels have various patterns of deterioration and condition monitoring period, it is necessary to consider a specific valuation method according to the condition of each road asset. Firstly, even though road pavements do not depreciate, asset valuation through condition-based depreciation method would be more appropriate when requirements for application of non-depreciation approach are not satisfied. Since bridge and tunnel facilities show various patterns of deterioration and condition monitoring period by type and condition level, consumption-based depreciation method based on deterioration model would be appropriate. Therefore, it is necessary to have a reasonable asset management system to apply condition-based depreciation method and a periodic condition investigation to manage road assets well.

• Journal of Genetic Medicine
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• v.17 no.2
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• pp.68-72
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• 2020

Purpose: Trisomy 21, the cause of Down syndrome (DS) with various medical problems, is the most common aneuploidy during the fetal period. For diagnosis, a non-invasive screening test using maternal blood, which cannot be confirmed and invasive confirmation test with a risk of miscarriage, may be performed. The trophoblast retrieval and isolation of the cervix (TRIC) have been proposed by some researchers as an alternative to overcome the limitations of current tests. We experimented using TRIC to identify the possibility of trisomy 21 for the first time in Asia. Materials and Methods: Three cases of DS were analyzed confirmed by invasive tests (chorionic villus sampling, amniocentesis). All samples of trophoblasts immediately were immersed in phosphate-buffered saline and processed with formalin for fixation. The trophoblasts were isolated using an anti-human leukocyte antigen-G antibody coupled to magnetic nanoparticles. β-human chorionic gonadotropin (hCG)-expressing cells were considered as trophoblast cells, and the detection rate calculated. DS was confirmed by fluorescence in situ hybridization (FISH). Results: The mean trophoblast detection rate using β-hCG was 78.1%, and the detection rate using FISH was 22.2%. In all cases, the trisomy of chromosome 21 was identified. Conclusion: Trophoblast can be obtained from the five weeks of gestation and has a high detection rate, so it is noted that it can replace the current prenatal genetic test. To realize the clinical application as a prenatal genetic test, we will need additional efforts to identify trisomy 21 as well as other chromosomal abnormalities in future large-scale studies.