• Title/Summary/Keyword: double integration

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The Usability Evaluation of Application that is Developed the Dynamic Kidney Phantom System in Nuclear Medicine

  • Kim, Jae-Hyun;Lee, Juyoung;Park, Hoon-Hee
    • Korean Journal of Digital Imaging in Medicine
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    • v.16 no.2
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    • pp.15-24
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    • 2014
  • Currently commercially available phantom can reproduce and evaluate only a static situation, the study is incomplete research on phantom and system which is can confirmed functional situation in the kidney by time through dynamic phantom and blood flow velocity, various difference according to the amount of radioactive. Therefore, through this study, it has produced the dynamic kidney phantom to reproduce images through the dynamic flow of the kidney, it desires to evaluate the usefulness of nuclear medicine imaging. The production of the kidney phantom was fabricated based on the normal adult kidney, in order to reproduce the dynamic situation based on the fabricated kidney phantom, in this study it was applied the volume pump that can adjust the speed of blood flow, so it can be integrated continuously radioactive isotopes in the kidney by using 99mTc-pertechnate. Used the radioactive isotope was supplied through the two pump. It was confirmed the changes according to the infusion rate, radioactive isotopes and the different injection speeds on the left and right, analysis of the acquired images was done by drawn five times ROI in order to check the reproducibility of each on the front and rear of the kidney and bladder. Depending on the speed of injection, radioisotope was a lot of integrated and emissions up when adjusting the pressure of the pump as 30 stroke, it was the least integrated and emissions up when adjusting as 40 stroke. The integration of the left & right kidney was not reached in the amount of the highest when adjusting as 10 stroke. In the changes according to the amount of the radioactive isotope, 0.6 mCi(22.2 MBq), 0.8 mCi (29.6 MBq)was showed up similar tendency but, in the result of the injection 0.8 mCi, it was showed up counts close to double of 0.6 mCi. In the result of the differently injection speed of the left & right kidney, as a result of different conditions that injection speed was 20 stroke through left kidney phantom, the injection speed was 30 stroke through right kidney phantom, it was enough difference in the resulting image can be easily distinguished with the naked eye. Through this study, the results showed that the dynamic kidney phantom system is able to similarly reproduce renogram in the actual clinical. Especially, the depicted over time for the flow to be excreted through the kidney into the bladder was adequately reproduce, it is expected to be utilized as basic data to check the quality of the dynamic images. In addition, it is considered to help in the field of functional imaging and quality control.

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Text integration processing based on connectives in Aphasics (실어증 환자의 접속사 정보처리에 관한 연구)

  • Kim, Soo-Jeong;Moon, Young-Sun;Kim, Mi-Ra;Kim, Yoo-Jeong;Nam, Ki-Chun
    • Annual Conference on Human and Language Technology
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    • 1999.10e
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    • pp.441-446
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    • 1999
  • 본 연구는 접속사를 통한 텍스트 통합 과정이 논리적 추론 종류에 따라 다른 정보처리 과정 혹은 다른 종류의 단원적 구조(modular structure in language processing)에 의해 처리되는지를 조사하기 위해 실시되었다. 또한, 접속사를 통한 추론 과정이 실어증의 증상 종류에 따라 다른 종류의 언어정보처리 손상이 있는지를 평가하기 위해 실시되었다. 실험에 참가한 환자는 이해성 실어증환자(Wernicke aphasic), 전반성 실어증 환자(Global aphasic), 표현성 실어증 환자(Broca aphasic) 등이었다. en 종류의 과제를 이용하였다. 한 과제는 앞 뒤 문장을 논리적 관계성을 표현하는 접속사를 채워 넣는 과제였고 다른 과제는 접속사가 포함된 텍스트가 옳은지를 판단하는 정오 판단 과제였다. 실험재료 문장에 사용된 접속사는 추가적인 정보를 제공하는 '그리고'와 대등 관계를 나타내는 '그러나' 및 인과 관계를 표현하는 '그래서' 였다. 이 세 종류의 접속사는 각기 다른 논리적 관계성을 나타낸다. 실험 결과는 실어증 환자가 전반적으로 채워 넣기 과제에서 보다는 정오 판단 과제에서 더 많은 실수를 보였으며, 표현성 실어증 환자보다는 이해성 실어증 환자가 더 많은 오류를 보였다. 또한, 세 종류의 접속사 중에 '그리고'가 표함된 텍스트에서 더 많은 실수를 보였다. 이 연구에서 나타난 흥미 있는 결과는 표현성 실어증 환자는 '그러나' 접속사가 포함된 텍스트에서의 수행이 '그래서'가 포함된 경우에서보다 좋은 반면에 전반성 실어증 환자는 '그래서'를 포함하는 텍스트에서의 수행이 '그러나'를 포함하는 텍스트에서의 수행이 더 우수해서 이중해리(double dissociation)가 나타난다는 사실이다. 이 결과는 선후 문장이 어떤 종류의 논리적 관계성을 지니는가에 따라 다른 종류의 정보처리가 진행된다는 것을 암시하는 결과이다.>$\textrm{cm}^2$.。C로 비교적 양호한 초전박막의 전기적 특성을 나타내었다.(Mg+Fe)비를 갖고 전자에 비해 Al이 풍부한 환경에서 생성되었으며, 따라서 활석과 연관되지 않은 녹니석은 생성시 광체와 인접한 화강아질 편마암에 의해 주로영향을 받았을 것으로 생각된다. 녹니석의 이러한 2가지 화학조성상의 경향은 녹니석과 공존하는 운모류나 각섬석류들의 화학분석결과와도 잘 일치한다. 이러한 결과는 이 지역의 활석 광상이 초염기성암 기원의 사문암이 열수변질작용을 받아 생성되었음을 명확하게 지시하며, 따라서 활석 광석내에 존재하는 녹니석은 활석의 근원 광물로서 녹니석편암 및 녹니석 편마암 매의 녹니석이 활석화되고 남은 잔존광물이 아니라, 주변암에 의해 성분상의 영향을 받은 열수와 사문암과의 변질교대작용에 의한 활석화과정 중에 주로 생성된 것으로 추정된다. 이러한 결과는 연구지역의 활석광상이 초염기성암의 사문암화 작용과 활석화 작용의 두 가지 변질작용에 의해 형성되어졌음을 알려준다.농도 증가 없이 폐 조직에 약 50배 정도의 고농도 cisplatin을 투여할 수 있었으며, 또한 분리 폐 관류 시 cisplatin에 의한 직접적 폐 독성은 발견되지 않았다이 낮았으나 통계학적 의의는 없었다[10.0%(4/40) : 8.2%(20/244), p>0.05]. 결론: 비디오흉강경술에서 재발을 낮추기 위해 수술시 폐야 전체를 관찰하여 존재하는 폐기포를 놓치지 않는 것이 중요하며, 폐기포를 확인하지 못한 경우와 이차성 자연기흉에 대해서는 흉막유착술에 더 세심한 주의가 필요하다는 것을 확인하였다. 비디오흉강경수술은 통증이 적고, 입원기간이 짧고, 사회로의 복귀가 빠르며, 고위험군에 적용할 수 있고, 무엇보다도 미용상의 이점이 크다는 면에서 자연기흉에 대해 유용한 치료방법임에는 틀림이 없으나 개흉술에 비해 재발율이 높고 비용이 비싸다는 문제가 제기되고 있는 만큼

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Acoustic characteristics of sound field in partially opened rooms - Emphasis on horizontal coupling of diffuse and non-diffuse field - (실내공간의 부분적 개방에 따른 음향특성변화 I - 확산음장과 자유음장의 수평적 결합을 중심으로 -)

  • Jeong, Dae-Up;Choi, Young-Ji;Kim, Ji-Young;Oh, Yang-Ki;Choi, Seok-Ju
    • Journal of Korean Association for Spatial Structures
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    • v.7 no.2 s.24
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    • pp.105-114
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    • 2007
  • Large span spaces have been widely used for various purposes including sports events in other countries. Due to increasing demands on multi-purpose use of such spaces, recently built large span sport facilities such dome stadiums have been required to accommodate sport events as well as performing events. Also, retractable ceilings and/or walls were generally adopted in those spaces for providing various event conditions. It seems obvious that the openings between diffuse fields and free field may cause difficulties in the acoustic design of such spaces In the present work, the acoustic characteristics of non-diffuse field has been investigated using 1/10 acoustic scale models. It was found that RTs at low- and mid-frequencies decayed faster than those at high-frequencies as the percentage of opening area increased. The decay rate of RTs at high frequencies were not influenced by increasing the area of an opening. Also high dependence of EDT on the percentage of opening area was observed at all frequency range. D50 was not improved by increasing the area of an opening up to 12.5% and then sharply increased. The application of Schroeder integration to evaluate the reverberation charateristics of coupled spaces may not be proper, since non-exponential decay process with double or triple decays of those spaces can not be properly defined. EDT seems more appropriate to predict reverberation at the early acoustic design stage of acoustically coupled spaces.

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A STUDY ON THE CHANGE OF IMPLANT STABILITY USING RESONANCE FREQUENCY ANALYSIS

  • Park Chan-Jin;Kim Yung-Soo;Kim Chang-Whe;Cho Lee-Ra;Yi Yang-Jin
    • The Journal of Korean Academy of Prosthodontics
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    • v.41 no.3
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    • pp.271-287
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    • 2003
  • Statement of problem: Resonance frequency analysis (RFA) has been increasingly served as a non-invasive and objective method for clinical monitoring of implant stability. Many clinical studies must be required for standardized baseline data using RFA. Purpose: This study was performed to evaluate RFA value changes in two stage surgery group and one stage surgery group in patients. Material and method: Forty-seven mandibles in consecutively implant installed patients were selected for this study and 141 fixtures were installed. Ninety-three fixtures were double threaded, machined surface design ($Br{\aa}anemark^{(R)}$ MK III, Nobel Biocare AB, Goteborg, Sweden) and 48 fixtures were root form, threaded, HA-coated surface one ($Replace^{TM}$, Steri-Oss/Nobel Biocare AB, USA). Among those, each 10 fixture was installed in one stage group patients. ISQ values were measured using $Osstell^{TM}$ (Integration Diagnostics Ltd. Sweden) during fixture installation, at healing abutment connection and in the loading period for two stage surgery group patients and during at each 4, 6, 8, 10, 12week and in the loading phase for one stage surgery group patients and evaluated the changes according to the time and fixture type. Results: In two stage surgery group, mean and SO of ISQ values of machined surface implants were $76.85{\pm}3.74,\;75.76{\pm}5.04,\;75.73{\pm}4.41$ and those of HA-coated surface implant were $75.05{\pm}6.23,\;77.58{\pm}5.23,\;78.32{\pm}4.29$ during fixtures installation, at healing abutment connection and in the loading period, respectively. In one-stage surgery group, the ISQ values of machined surface and HA-coated surface implants decreased until 4 or 6 week and maintained at plateau for 1-3 week and increased to the loading period. Conclusions: Machined and HA-coated surface implants showed minimal ISQ changes with time if they were installed at the sites showing at least intact cortical plate and good bone qualities. And HA-coated implants had a tendency to show somewhat increased ISQ values with time.

Study on the Emergency Assessment about Seismic Safety of Cable-supported Bridges using the Comparison of Displacement due to Earthquake with Disaster Management Criteria (변위 비교를 통한 케이블지지교량의 긴급 지진 안전성 평가 방법의 고찰)

  • Park, Sung-Woo;Lee, Seung Han
    • Journal of the Korea institute for structural maintenance and inspection
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    • v.22 no.6
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    • pp.114-122
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    • 2018
  • This study presents the emergency assessment method about seismic safety of cable-supported bridges using seismic acceleration sensors installed on the primary structural elements of them. The structural models of bridges are updated iteratively to make their dynamic characteristics to be similar to those of real bridges based on the comparison of their natural frequencies with those of real bridges estimated from acceleration data measured at ordinary times by the seismic acceleration sensor. The displacement at the location of each seismic acceleration sensor is derived by seismic analysis using design earthquake, and the peak value of them is determined as the disaster management criteria in advance. The displacement time history is calculated by the double integration of the acceleration time history which is recorded at each seismic acceleration sensor and filtered by high cut(low pass) and low cut(high pass) filters. Finally, the seismic safety is evaluated by the comparison of the peak value in calculated displacement time history with the disaster management criteria determined in advance. The applicability of proposed methodology is verified by performing the seismic safety assessment of 12 cable-supported bridges using the acceleration data recorded during Gyeongju earthquake.

Analysis of Current Limiting Characteristics According to Fault Angles in Integrated Three-Phase Flux-Lock Type Superconducting Fault Current Limiting (일체화된 삼상 자속구속형 고온초전도 전류제한기의 사고각에 따른 전류제한 특성 분석)

  • Park, Chung-Ryul;Du, Ho-Ik;Yim, Seong-Woo;Hyun, Ok-Bae;Lim, Sung-Hun;Park, Hyoung-Min;Cho, Yong-Sun;Nam, Gueng-Hyun;Lee, Na-Young;Choi, Hyo-Sang;Han, Byoung-Sung
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2006.06a
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    • pp.255-256
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    • 2006
  • In this paper, we investigated the. characteristics of fault current limiting according to fault angle in the integrated three-phase flux-lock type SFCL in fault types such as the single-line-to-ground fault, the double-line-to-ground fault and the three-line-to-ground fault. When the SFCL is operating under normal condition, the magnetic flux generated between primary and secondary coils of each single phase is canceled out perfectly, so that the impedance of the SFCL is also not generated and the power system can be operated normally without any loss, However, if a fault occurs even in any phase out of three phases, quench happened in SFCL elements and the current flowing secondary coil is restricted abruptly. Finally, the balance of magnetic flux in whole SFCL system is destroyed, and the fault currents in every phase could be limited at the same time irrespective of the fault types. As a result, the developed SFCL in this study were operated normally as expected and the purpose of the integration of 3 phase current limiting was also achieved successfully. However, the fault current limiting characteristics of the SFCL was dependant on the quench characteristics of HTSC elements in each phase, and it was expected that the improvement of the SFCL could be possible through the introduction of HTSC elements which have better critical characteristics.

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Integrated Photonic Microwave Bandpass Filter Incorporating a Polymer Microring Resonator (폴리머 마이크로링 공진기를 이용한 광학적 마이크로웨이브 대역통과 필터)

  • Chin, Won-Jun;Kim, Do-Hwan;Song, Ju-Han;Lee, Sang-Shin
    • Korean Journal of Optics and Photonics
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    • v.16 no.5
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    • pp.469-475
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    • 2005
  • An integrated photonic microwave bandpass filter has been proposed and demonstrated incorporating a coherently coupled microring resonator in low-loss polymers. The proposed device may feature compact site, simple structure, tuning via the thermooptic and electrooptic effect, and flexible integration with other electrical and optical devices. The resonator was designed to have an extremely small bandwidth so that it could be used to selectively pass the optical signal carrying the microwave signal to attain efficient bandpass filtering. We made and tested two resonators with a single ring and double rings, and performed a theoretical fitting of their measured transfer curves to predict the performance of the microwave filters based on them precisely. It was found that as the number of the rings used for the resonator increases, the bandwidth gets smaller, the rolloff sharper, and the band rejection higher. Finally our filter exhibited the center frequency of 10GHz, the 3-dB bandwidth of 1.0GHz, the corresponding quality (Q) factor of 10, and the rejection outside of the passband of more than 25dB.

Finite element method adopting isoparametric formulation of the quadrilateral elements (등매개변수 사변형요소를 적용한 유한요소해석법)

  • Lee, Seung-Hyun;Han, Jin-Tae
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.19 no.11
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    • pp.205-212
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    • 2018
  • In order to overcome shortcomings of commercial analysis program for solving certain geotechnical problems, finite element method adopting isoparametric quadrilateral element was selected as a tool for analyzing soil behavior and calculating process was programmed. Two examples were considered in order to verify reliability of the developed program. One of the two examples is the case of acting isotropic confining pressure on finite element and the other is the case of acting shear stress on the sides of the finite element. Isoparametric quadrilateral element was considered as the finite element and displacements in the element can be expressed by node displacements and shape functions in the considered element. Calculating process for determining strain which is defined by derivatives using global coordinates was coded using the Jacobian and the natural coordinates. Four point Gauss rule was adopted to convert double integral which defines stiffness of the element into numerical integration. As a result of executing analysis of the finite element under isotropic confining pressure, calculated stress corresponding to four Gauss points and center of the element were equal to the confining pressure. In addition, according to the analyzed results for the element under shear stress, horizontal stresses and vertical stresses were varied with positions in the element and the magnitudes and distribution pattern of the stresses were thought to be rational.

Transactional Analysis and integrated application of Psychodrama: Focusing on drama triangle (교류분석과 사이코드라마의 통합적인 적용 - 드라마 삼각모형을 중심으로 -)

  • Chin, Hye Jeon
    • The Korean Journal of Psychodrama
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    • v.21 no.2
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    • pp.73-95
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    • 2018
  • The purpose of this study is to show an example of the integrated application of The Transactional Analysis and Psychodrama in order to help various experimental attempts and Empowering of psychodramatists. The Drama Triangle, a game model developed by Kaufman, can be well explained through the Psychodrama. Linda Condon introduced role reversal, mirroring, and auxiliary ego, double ego technique that helps act in psychodrama through a model for restoring dysfunction. The Acting out of Psychodrama provides emotional experiences and experiences that can not be presented in Transactional analysis. Through the couching technique Psychodrama, it is possible to accurately inform the situation of the victim, the persecutor, and the rescuer who plays the psychological game. Also, couching technique can perform role training for solution. The concept of the ego state of The Transactional analysis can be useful for the director to understand the Protagonist's language and attitude and to set the scene. This paper shows an example of the application of the Transactional Analysis approach and the Psychodrama integration through the act of the drama triangle game, which is the concept of Transactional Analysis, and it is meaningful to propose a circular relationship framework of the role developed by the author .

Cigarette Smoke Extract-Treated Mouse Airway Epithelial Cells-Derived Exosomal LncRNA MEG3 Promotes M1 Macrophage Polarization and Pyroptosis in Chronic Obstructive Pulmonary Disease by Upregulating TREM-1 via m6A Methylation

  • Lijing Wang;Qiao Yu;Jian Xiao;Qiong Chen;Min Fang;Hongjun Zhao
    • IMMUNE NETWORK
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    • v.24 no.2
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    • pp.3.1-3.23
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    • 2024
  • Cigarette smoke extract (CSE)-treated mouse airway epithelial cells (MAECs)-derived exosomes accelerate the progression of chronic obstructive pulmonary disease (COPD) by upregulating triggering receptor expressed on myeloid cells 1 (TREM-1); however, the specific mechanism remains unclear. We aimed to explore the potential mechanisms of CSE-treated MAECs-derived exosomes on M1 macrophage polarization and pyroptosis in COPD. In vitro, exosomes were extracted from CSE-treated MAECs, followed by co-culture with macrophages. In vivo, mice exposed to cigarette smoke (CS) to induce COPD, followed by injection or/and intranasal instillation with oe-TREM-1 lentivirus. Lung function and pathological changes were evaluated. CD68+ cell number and the levels of iNOS, TNF-α, IL-1β (M1 macrophage marker), and pyroptosis-related proteins (NOD-like receptor family pyrin domain containing 3, apoptosis-associated speck-like protein containing a caspase-1 recruitment domain, caspase-1, cleaved-caspase-1, gasdermin D [GSDMD], and GSDMD-N) were examined. The expression of maternally expressed gene 3 (MEG3), spleen focus forming virus proviral integration oncogene (SPI1), methyltransferase 3 (METTL3), and TREM-1 was detected and the binding relationships among them were verified. MEG3 increased N6-methyladenosine methylation of TREM-1 by recruiting SPI1 to activate METTL3. Overexpression of TREM-1 or METTL3 negated the alleviative effects of MEG3 inhibition on M1 polarization and pyroptosis. In mice exposed to CS, EXO-CSE further aggravated lung injury, M1 polarization, and pyroptosis, which were reversed by MEG3 inhibition. TREM-1 overexpression negated the palliative effects of MEG3 inhibition on COPD mouse lung injury. Collectively, CSE-treated MAECs-derived exosomal long non-coding RNA MEG3 may expedite M1 macrophage polarization and pyroptosis in COPD via the SPI1/METTL3/TREM-1 axis.