• Journal of Radiation Protection and Research
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• 제32권4호
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• pp.158-167
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• 2007

본 논문의 목적은 노외 중성자 선량 감시자를 이용하여 원자로 압력용기 중성자 조사취화의 핵심 요인이 되는 고속중성자 ($1{\ge}MeV$) 조사량 평가 방법을 제시하고 적용성을 검증하는 것이다. 다양한 중성자 반응에너지를 갖는 다수의 선량감시자를 원자로 외벽 보온 단열재와 1차 생물학적 차폐체 사이의 공간에 설치하고 한 주기 동안 조사시킨 후 인출하여 생성핵종에 대한 방사선을 측정하여 반응률을 도출하였다. 또한 상업용 코드를 이용한 중성자 수송계산을 통해 감시자 위치에서의 중성자 스펙트럼을 계산하였다. 두 결과로부터 감시자에 대한 반응률을 직접 비교할 수 있었으며 또한 최소자승 조정 절차를 통해 최적의 중성자 스펙트럼도 도출할 수 있었다. 감시자 측정 결과와 해석적으로 계산한 중성자 조사량 사이에는 관련 규정에서 제시한 ${\pm}30%$ 이내의 오차를 보였다.

• 한국의학물리학회지:의학물리
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• 제29권1호
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• pp.16-22
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• 2018

Current dosimetry protocols recommend the use of parallel-plate chambers in electron dosimetry because the electron fluence perturbation can be effectively minimized. However, substitutable methods to calibrate and measure the electron output and energy with the widely used cylindrical chamber should be developed in case a parallel-plate chamber is unavailable. In this study, we measured the correction factors and absolute dose-to-water of electrons with energies of 4, 6, 9, 12, 16, and 20 MeV using Farmer-type and Roos chambers by varying the dose rates according to the AAPM TG-51 protocol. The ion recombination factor and absolute dose were found to be varied across the chamber types, energy, and dose rate, and these phenomena were remarkable at a low energy (4 MeV), which was in good agreement with literature. While the ion recombination factor showed a difference across chamber types of less than 0.4%, the absolute dose differences between them were largest at 4 MeV at approximately 1.5%. We therefore found that the absolute dose with respect to the dose rate was strongly influenced by ion-collection efficiency. Although more rigorous validation with other types of chambers and protocols should be performed, the outcome of the study shows the feasibility of replacing the parallel-plate chamber with the cylindrical chamber in electron dosimetry.

• Nuclear Engineering and Technology
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• 제38권3호
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• pp.239-250
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• 2006

Computational anthropomorphic phantoms are computer models of human anatomy used in the calculation of radiation dose distribution in the human body upon exposure to a radiation source. Depending on the manner to represent human anatomy, they are categorized into two classes: stylized and tomographic phantoms. Stylized phantoms, which have mainly been developed at the Oak Ridge National Laboratory (ORNL), describe human anatomy by using simple mathematical equations of analytical geometry. Several improved stylized phantoms such as male and female adults, pediatric series, and enhanced organ models have been developed following the first hermaphrodite adult stylized phantom, Medical Internal Radiation Dose (MIRD)-5 phantom. Although stylized phantoms have significantly contributed to dosimetry calculation, they provide only approximations of the true anatomical features of the human body and the resulting organ dose distribution. An alternative class of computational phantom, the tomographic phantom, is based upon three-dimensional imaging techniques such as magnetic resonance (MR) imaging and computed tomography (CT). The tomographic phantoms represent the human anatomy with a large number of voxels that are assigned tissue type and organ identity. To date, a total of around 30 tomographic phantoms including male and female adults, pediatric phantoms, and even a pregnant female, have been developed and utilized for realistic radiation dosimetry calculation. They are based on MRI/CT images or sectional color photos from patients, volunteers or cadavers. Several investigators have compared tomographic phantoms with stylized phantoms, and demonstrated the superiority of tomographic phantoms in terms of realistic anatomy and dosimetry calculation. This paper summarizes the history and current status of both stylized and tomographic phantoms, including Korean computational phantoms. Advantages, limitations, and future prospects are also discussed.

• Journal of Radiation Protection and Research
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• 제19권3호
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• pp.189-198
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• 1994

Teledyne 9150 판독장치에서 사용되는 PB-3 열형광선량계의 방향의존성에 관한 실험을 실시하였고 ANSI N13.11-1992에 의거하여 성능실험을 실시하였다. 조사선원은 $^{137}Cs$과 X선이었다. Teledyne 9150 선량판독장치는 $0^{\circ}$에서는 모든 경우에 방향의존성에 대한 성능시험범주를 만족하였다. 그러나 저에너지 X선의 경우, ${\pm}60^{\circ}$에서는 방향의존성에 대한 성능시험범주를 만족할 수 없었으며 $^{137}Cs$은 모든 경우에 방향의존성에 대한 성능시험범주를 만족하였다.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.252-254
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• 2002

A new protocol for dosimetry in external beam radiotherapy is published by the Japan Society of Medical Physics (JSMP) in 2002. The protocol deals with proton and heavy ion beams as well as photon and electron beams, in accordance with IAEA Technical Report Series No. 398. To establish inter-institutional uniformity in proton beam dosimetry, an intercomparison program was carried out with the new protocol. The absorbed doses are measured with different cylindrical ionization chambers in a water phantom at a position of 30-mm residual range for a proton beam, that had range of 155 mm and a spread out Bragg peak (SOBP) of 60-mm width. As a result, the intercomparison showed that the use of the new protocol would improve the +/- 1.0 % (one standard deviation) and 2.7 % (maximum discrepancy) differences in absorbed doses stated by the participating institutions to +/- 0.3% and 0.9 %, respectively. The new protocol will be adopted by all of the participants.

• Journal of Radiation Protection and Research
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• 제32권3호
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• pp.111-115
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• 2007

원자력 발전소의 중수누출에 따른 삼중수소 농도증가에 의한 방사선 내부피폭과 이에 대한건강영향평가를 실시하였다. 전체 22명 가운데 13명에 대하여 검사를 실시하였으며, 이들의 내부피폭량은 $0{\sim}4.44\;mSv$ 였다. 일반혈액검사 중 백혈구수치의 변화를 이용하여 평가한 결과에서 결정적 영향에 대한 특이사항은 나타나지 않았으며, 생물학적 선량평가 방법을 이용한 체내피폭량은 $0{\sim}37\;mGy$로 확인되었다. 결론적으로 방사선 피폭은 허용한도를 초과하지 않았으며, 결정적 영향인 임상적 증상이 보이지 않았다. 이와 같이 의학적 징후와 선량평가 추정치와의 일치성은 사고시 특히 물리적 생물학적 선량평가가 유용함을 보여 준다.

• 대한의용생체공학회:의공학회지
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• 제20권2호
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• pp.199-204
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• 1999

생체조직내의 정확한 광선량 측정이 PDT 치료의 효과에 중요한 영향을 주므로 본 연구에서는 광선량 측정을 위해서 Monte Carlo 시뮬레이션을 이용하였다. 실험에 사용한 계수는 실제 생체조직의 광학계수이고 위상함수는 Henyey-Greenstein 위상함수를 사용하였다. 결과는 깊이에 따른 Fluency rate의 변화로 나타내었으며 기존 이론과의 차이는 0.35%에 지나지 않았다. 실험에 사용한 생체조직은 인체조직, 돼지조직, 쥐간조직, 토기근육조직이다. 대부분의 생체조직은 가시광선영역에서 큰 산란계수를 가지고 있으며 이것은 투과도에 큰 영향을 미치는 것으로 밝혀졌다. 가시광선 영역에서 인체조직의 투과 깊이는 1.5~2cm이었다. Monte Carlo 시뮬레이션을 이용하여 생체조직내의 광전파(light propagation), 광선량(light dosimetry), 에너지율(fluence rate), 투과깊이(penetration depth)를 효과적으로 측정할 수 있음을 보여주었다.

• 한국의학물리학회지:의학물리
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• 제31권4호
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• pp.145-152
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• 2020

Purpose: In ionization-chamber dosimetry for high-dose-rate electron beams-above 20 mGy/pulse-the ion-recombination correction methods recommended by the International Atomic Energy Agency (IAEA) and the American Association of Physicists in Medicine (AAPM) are not appropriate, because they overestimate the correction factor. In this study, we suggest a practical ion-recombination correction method, based on Boag's improved model, and apply it to reference dosimetry for electron beams of about 100 mGy/pulse generated from an electron linear accelerator (LINAC). Methods: This study employed a theoretical model of the ion-collection efficiency developed by Boag and physical parameters used by Laitano et al. We recalculated the ion-recombination correction factors using two-voltage analysis and obtained an empirical fitting formula to represent the results. Next, we compared the calculated correction factors with published results for the same calculation conditions. Additionally, we performed dosimetry for electron beams from a 6 MeV electron LINAC using an Advanced Markus^® ionization chamber to determine the reference dose in water at the source-to-surface distance (SSD)=100 cm, using the correction factors obtained in this study. Results: The values of the correction factors obtained in this work are in good agreement with the published data. The measured dose-per-pulse for electron beams at the depth of maximum dose for SSD=100 cm was 115 mGy/pulse, with a standard uncertainty of 2.4%. In contrast, the k_s values determined using the IAEA and AAPM methods are, respectively, 8.9% and 8.2% higher than our results. Conclusions: The new method based on Boag's improved model provides a practical method of determining the ion-recombination correction factors for high dose-per-pulse radiation beams up to about 120 mGy/pulse. This method can be applied to electron beams with even higher dose-per-pulse, subject to independent verification.

• 대한방사선기술학회지:방사선기술과학
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• 제43권6호
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• pp.431-441
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• 2020

The purpose of this study was to construct a model of MVCT(Megavoltage Computed Tomography) dose calculation by using Dosimetry Check™, a program that radiation treatment dose verification, and establish a protocol that can be accumulated to the radiation treatment dose distribution. We acquired sinogram of MVCT after air scan in Fine, Normal, Coarse mode. Dosimetry Check™(DC) program can analyze only DICOM(Digital Imaging Communications in Medicine) format, however acquired sinogram is dat format. Thus, we made MVCT RC-DICOM format by using acquired sinogram. In addition, we made MVCT RP-DICOM by using principle of generating MLC(Multi-leaf Collimator) control points at half location of pitch in treatment RP-DICOM. The MVCT imaging dose in fine mode was measured by using ionization chamber, and normalized to the MVCT dose calculation model, the MVCT imaging dose of Normal, Coarse mode was calculated by using DC program. As a results, 2.08 cGy was measured by using ionization chamber in Fine mode and normalized based on the measured dose in DC program. After normalization, the result of MVCT dose calculation in Normal, Coarse mode, each mode was calculated 0.957, 0.621 cGy. Finally, the dose resulting from the process for acquisition of MVCT can be accumulated to the treatment dose distribution for dose evaluation. It is believed that this could be contribute clinically to a more realistic dose evaluation. From now on, it is considered that it will be able to provide more accurate and realistic dose information in radiation therapy planning evaluation by using Tomotherapy.

• 한국의학물리학회지:의학물리
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• 제34권3호
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• pp.33-39
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• 2023

Purpose: FLASH radiotherapy (RT) using ultra-high dose rate (>40 Gy/s) radiation is being studied worldwide. However, experimental studies such as preclinical studies using small animals are difficult to perform due to the limited availability of irradiation devices and methods for generating a FLASH beam. In this paper, we report the initial dosimetry results of a prototype electron linear accelerator (LINAC)-based irradiation system to perform ultra-high dose rate (UHDR) preclinical experiments. Methods: The present study used the prototype electron LINAC developed by the Research Center of Dongnam Institute of Radiological and Medical Sciences (DIRAMS) in Korea. We investigated the beam current dependence of the depth dose to determine the optimal beam current for preclinical experiments. The dose rate in the UHDR region was measured by film dosimetry. Results: Depth dose measurements showed that the optimal beam current for preclinical experiments was approximately 33 mA, corresponding to a mean energy of 4.4 MeV. Additionally, the average dose rates of 80.4 Gy/s and 162.0 Gy/s at a source-to-phantom surface distance of 30 cm were obtained at pulse repetition frequencies of 100 Hz and 200 Hz, respectively. The dose per pulse and instantaneous dose rate were estimated to be approximately 0.80 Gy and 3.8×10⁵ Gy/s, respectively. Conclusions: Film dosimetry verified the appropriate dose rates to perform FLASH RT preclinical studies using the developed electron-beam irradiator. However, further research on the development of innovative beam monitoring systems and stabilization of the accelerator beam is required.