Browse > Article
http://dx.doi.org/10.14316/pmp.2020.31.4.145

High-Dose-Rate Electron-Beam Dosimetry Using an Advanced Markus Chamber with Improved Ion-Recombination Corrections  

Jeong, Dong Hyeok (Research center, Dongnam Institute of Radiological and Medical Sciences)
Lee, Manwoo (Research center, Dongnam Institute of Radiological and Medical Sciences)
Lim, Heuijin (Research center, Dongnam Institute of Radiological and Medical Sciences)
Kang, Sang Koo (Research center, Dongnam Institute of Radiological and Medical Sciences)
Jang, Kyoung Won (Research center, Dongnam Institute of Radiological and Medical Sciences)
Publication Information
Progress in Medical Physics / v.31, no.4, 2020 , pp. 145-152 More about this Journal
Abstract
Purpose: In ionization-chamber dosimetry for high-dose-rate electron beams-above 20 mGy/pulse-the ion-recombination correction methods recommended by the International Atomic Energy Agency (IAEA) and the American Association of Physicists in Medicine (AAPM) are not appropriate, because they overestimate the correction factor. In this study, we suggest a practical ion-recombination correction method, based on Boag's improved model, and apply it to reference dosimetry for electron beams of about 100 mGy/pulse generated from an electron linear accelerator (LINAC). Methods: This study employed a theoretical model of the ion-collection efficiency developed by Boag and physical parameters used by Laitano et al. We recalculated the ion-recombination correction factors using two-voltage analysis and obtained an empirical fitting formula to represent the results. Next, we compared the calculated correction factors with published results for the same calculation conditions. Additionally, we performed dosimetry for electron beams from a 6 MeV electron LINAC using an Advanced Markus® ionization chamber to determine the reference dose in water at the source-to-surface distance (SSD)=100 cm, using the correction factors obtained in this study. Results: The values of the correction factors obtained in this work are in good agreement with the published data. The measured dose-per-pulse for electron beams at the depth of maximum dose for SSD=100 cm was 115 mGy/pulse, with a standard uncertainty of 2.4%. In contrast, the ks values determined using the IAEA and AAPM methods are, respectively, 8.9% and 8.2% higher than our results. Conclusions: The new method based on Boag's improved model provides a practical method of determining the ion-recombination correction factors for high dose-per-pulse radiation beams up to about 120 mGy/pulse. This method can be applied to electron beams with even higher dose-per-pulse, subject to independent verification.
Keywords
Ion recombination correction factor; Dose-per-pulse; Advanced Markus chamber; Boag model; Electron beam dosimetry;
Citations & Related Records
Times Cited By KSCI : 4  (Citation Analysis)
연도 인용수 순위
1 Schuler E, Trovati S, King G, Lartey F, Rafat M, Villegas M, et al. Experimental platform for ultra-high dose rate FLASH irradiation of small animals using a clinical linear accelerator. Int J Radiat Oncol Biol Phys. 2017;97:195-203.   DOI
2 McManus M, Romano F, Lee ND, Farabolini W, Gilardi A, Royle G, et al. The challenge of ionisation chamber dosimetry in ultra-short pulsed high dose-rate Very High Energy Electron beams. Sci Rep. 2020;10:9089.   DOI
3 Boag JW, Hochhauser E, Balk OA. The effect of free-electron collection on the recombination correction to ionization measurements of pulsed radiation. Phys Med Biol. 1996;41:885-897.   DOI
4 Pearce JAD. Characterisation of two new ionisation chamber types for use in reference electron dosimetry in the UK. Teddington: National Physical Laboratory. 2004; NPL Report DQL-RD001.
5 Lim H, Lee M, Kim MY, Yi J, Lee M, Kang SK, et al. Measurement of energy parameters for electron gun heater currents and output dose rate for electron beams from a prototype linac. Prog Med Phys. 2016;27:25-30.   DOI
6 Laitano RF, Guerra AS, Pimpinella M, Caporali C, Petrucci A. Charge collection efficiency in ionization chambers exposed to electron beams with high dose per pulse. Phys Med Biol. 2006;51:6419-6436.   DOI
7 Nisbet A, Thwaites DI. Polarity and ion recombination correction factors for ionization chambers employed in electron beam dosimetry. Phys Med Biol. 1998;43:435-443.   DOI
8 Almond PR, Biggs PJ, Coursey BM, Hanson WF, Huq MS, Nath R, et al. AAPM's TG-51 protocol for clinical reference dosimetry of high-energy photon and electron beams. Med Phys. 1999;26:1847-1870.   DOI
9 Pimpinella M, Andreoli S, De Angelis C, Della Monaca S, D'Arienzo M, Menegotti L. Output factor measurement in high dose-per-pulse IORT electron beams. Phys Med. 2019;61:94-102.   DOI
10 Montay-Gruel P, Petersson K, Jaccard M, Boivin G, Germond JF, Petit B, et al. Irradiation in a flash: unique sparing of memory in mice after whole brain irradiation with dose rates above 100Gy/s. Radiother Oncol. 2017;124:365-369.   DOI
11 Petersson K, Jaccard M, Germond JF, Buchillier T, Bochud F, Bourhis J, et al. High dose-per-pulse electron beam dosimetry - a model to correct for the ion recombination in the Advanced Markus ionization chamber. Med Phys. 2017;44:1157-1167.   DOI
12 Gotz M. Dosimetry of highly pulsed radiation fields. Dresden: Helmholtz-Zentrum Dresden-Rossendorf. 2018;HZDR-090.
13 Jang KW, Lee M, Lim H, Kang SK, Lee SJ, Kim JK, et al. Development of a wide dose-rate range electron beam irradiation system for pre-clinical studies and multi-purpose applications using a research linear accelerator. Prog Med Phys. 2020;31:9-19.   DOI
14 International Atomic Energy Agency. Absorbed dose determination in external beam radiotherapy: an international code of practice for dosimetry based on standards of absorbed dose to water. Vienna: International Atomic Energy Agency. 2006; IAEA TRS-398.
15 Kry SF, Popple R, Molineu A, Followill DS. Ion recombination correction factors (P(ion)) for Varian TrueBeam high-dose-rate therapy beams. J Appl Clin Med Phys. 2012;13:318-325.   DOI
16 Lim H, Jo W, Lee DE, Lee M, Kim SH, Shin SW, et al. Status of the DIRAMS C-band standing-wave accelerator for a radiotherapy machine. Paper presented at: 9th Asia Forum for Accelerators and Detectors; 2018 Jan 28-31; Daejeon, Korea. p. 38.
17 Ding GX, Rogers DW. Mean energy, energy-range relationships and depth-scaling factors for clinical electron beams. Med Phys. 1996;23:361-376.   DOI