• Title/Summary/Keyword: dose conversion

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Construction of MIRD-type Korean Adult Male Phantom and Calculation of Dose Conversion Coefficients for Photon (한국 성인남성 MIRD형 모의피폭체 제작 및 광자 외부피폭 선량환산인자 산출)

  • Park, Sang-Hyun;Lee, Choon-Sik;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.29 no.2
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    • pp.97-104
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    • 2004
  • MIRD-type Korean adult male phantom, 'KMIRD' was constructed to calculate Korean-specific dosimetric quantities for radiation protection consideration. The external shape of KMIRD was based on national physical standard data of Korean. KMIRD has thicket trunk than MIRD5 and arm models divided from trunk. The height and weight of the KMIRD are 171 cm and 63.8 kg. ICRP23 data were referred to constitute organs and tissues of KMIRD. However nine organs were constructed based on Korean reference data provided by Radiation Health Research Institute. In the present study, the MCNPX2.3 Monte Carlo transport code was combined with KMIRD to calculate dose conversion coefficients for photon in the energy range from 0.05 to 10 MeV. The simulated irradiation geometries are broad parallel photon beams in AP, PA, LLAT and RLAT direction. Absorbed dose conversion coefficients were compared with data calculated with MIRD5, MIRD-type phantom based on ICRP23 reference man. In some organs, the discrepancies between two phantoms amount up to nearly 30%. The effective doses conversion coefficients of KMIRD are lower than those of MIRD5. The dose discrepancies between two MIRD-type phantoms ate because of physical differences between Korean and Western, also geometric differences between two phantoms. KMIRD should be revised using the full set of Korean reference data of all organs. The developed MIRD-type Korean adult male phantom can be applied to dose assessment of internal exposure.

Average and Effective Energies, and Fluence-Dose Equivalent Conversion Factors for $^{239}Pu-Be,\;^{241}Am-Li\;and\;^{241}Am-F$ Neutron Sources

  • Ro, Seung-Gy;Yoo, Young-Soo
    • Nuclear Engineering and Technology
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    • v.3 no.3
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    • pp.155-160
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    • 1971
  • Average and effective energies for 239Pu-Be, 241Am-Li and 241Am-F neutron sources have been calculated from a number of published data for the neutron spectra and for the dose equivalent as a function of neutron energies by a numerical method. Also a calculation of the dose equivalent conversion factors, i. e., the first collision dose equivalent and the surface (or multicollision) dose equivalent that equals the product of surface-absorbed dose and a corresponding quality factor, per unit fluence of neutrons from these sources has been carried out in the same way as before. The results are as follows : 1. for average energies 4.07$\pm$0.33, 0.42 and 1.41 MeV; 2. for effective energies based on the concept of the first collision process in the human body 4.45$\pm$0.344, 0.51 and 1.47 MeV; 3. for effective energies based on the concept of the multi-collision process in the human body 4.50$\pm$0.36, 0.50 and 1.45 MeV; 4. for fluence-first collision dose equivalent conversion factors (2.74$\pm$0.07)10$^{-8}$ , 1.58$\times$ 10$^{-8}$ and 2.34$\times$10$^{-8}$ rems/(n/$\textrm{cm}^2$); and 5. for fluence-surface dose equivalent conversion factors (3.55$\pm$0.09)10$^{-8}$ , 2.19$\times$10$^{-8}$ and 2.82$\times$10$^{-8}$ rems/(n/$\textrm{cm}^2$) : respectively.

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Neutron dosimetry with a pair of TLDs for the Elekta Precise medical linac and the evaluation of optimum moderator thickness for the conversion of fast to thermal neutrons

  • Marziyeh Behmadi;Sara Mohammadi;Mohammad Ehsan Ravari;Aghil Mohammadi;Mahdy Ebrahimi Loushab;Mohammad Taghi Bahreyni Toossi;Mitra Ghergherehchi
    • Nuclear Engineering and Technology
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    • v.56 no.2
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    • pp.753-761
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    • 2024
  • Introduction: In this study, TLD 600 and TLD 700 pairs were used to measure the neutron dose of Elekta Precise medical linac. To this end, the optimum moderate thickness for the conversion of fast to thermal neutrons were evaluated. Materials and methods: 241Am-Be and 252Cf sources were simulated to calculate the optimum thicknesses of the moderator for the conversion of maximum fast neutrons (FN) into thermal neutrons (TN). Pair TLDs were used to measure F&TN doses for three different field sizes at four depths of the medical linac. Results: The maximum thickness of the moderator was optimized at 6 cm. The measurement results demonstrated that the TN dose increased with the expansion of field size and depth. The FN dose, which was converted TN, exhibits behaviors comparable to the TN due to its nature. Conclusion: This study presents the optimum thickness for the moderator to convert FN into TN and measure F&TN using TLDs.

The Effect of Hydrogen Peroxide-Treated Metallothionein on the Hepatic Xanthine Oxidase Activity

  • Huh, Keun;Shin, Uk-Seob;Lee, Sang-Il
    • BMB Reports
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    • v.28 no.6
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    • pp.490-493
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    • 1995
  • We investigated the effect of hydrogen peroxide-treated metallothionein on the hepatic xanthine oxidase activity in vitro. When the metallothionein was preincubated with 1 mM of hydrogen peroxide, the activity of xanthine oxidase and type conversion were elevated dose-dependently by the addition of metallothionein into the reaction mixture. While increasing the treatment of hydrogen peroxide to the $50{\mu}g$of metallothionein, the xanthine oxidase activity and type conversion ratio were remarkably elevated dose dependently compared to the control. When cadmium ion was added to the reaction mixture, the increasing pattern of the enzyme activity was similar to the effect of hydrogen peroxide-treated metallothionein. DTT or penicillamine restored the increasing activity and type conversion of xanthine oxidase by the cadmium ion to the control level.

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Oxidative Conversion of Bisphenol A with Laccase in the Presence of Polyethylene Glycol (Polyethylene glycol (PEG) 수용액에서 laccase를 이용한 비스페놀A의 처리)

  • Kim, Young-Jin
    • Journal of Environmental Health Sciences
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    • v.31 no.4 s.85
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    • pp.241-245
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    • 2005
  • Laccase catalyzes the oxidation and polymerization of aromatic compounds in the presence of molecular oxygen. Studies were conducted to characterize the use of polyethylene glycol (PEG) as an additive to keep up the enzymatic stability. The enzymatic activities highly remained and bisphenol A (BPA) was rapidly converted in the presence of 5 mg/l of PEC. These effects were accomplished with PEG of molecular weight 3,350. A linear relationship was found between the quantity of BPA to be converted $(10-120\;{\mu}M)$ and the optimum dose of PEC required for greater than $95\%$ conversion. This result suggests that it is the interaction between the PEG and the reaction products. In the optimum dose of PEG, the aeration of reaction mixture neither enhanced the conversion of BPA nor retarded the inactivation of the enzyme.

DEVELOPMENT OF POINT KERNEL SHIELDING ANALYSIS COMPUTER PROGRAM IMPLEMENTING RECENT NUCLEAR DATA AND GRAPHIC USER INTERFACES

  • Kang, Sang-Ho;Lee, Seung-Gi;Chung, Chan-Young;Lee, Choon-Sik;Lee, Jai-Ki
    • Journal of Radiation Protection and Research
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    • v.26 no.3
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    • pp.215-224
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    • 2001
  • In order to comply with revised national regulationson radiological protection and to implement recent nuclear data and dose conversion factors, KOPEC developed a new point kernel gamma and beta ray shielding analysis computer program. This new code, named VisualShield, adopted mass attenuation coefficient and buildup factors from recent ANSI/ANS standards and flux-to-dose conversion factors from the International Commission on Radiological Protection (ICRP) Publication 74 for estimation of effective/equivalent dose recommended in ICRP 60. VisualShieid utilizes graphical user interfaces and 3-D visualization of the geometric configuration for preparing input data sets and analyzing results, which leads users to error free processing with visual effects. Code validation and data analysis were performed by comparing the results of various calculations to the data outputs of previous programs such as MCNP 4B, ISOSHLD-II, QAD-CGGP, etc.

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Risk Assessment for Noncarcinogenic Chemical Effects

  • Kodell Ralph L.
    • 대한예방의학회:학술대회논문집
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    • 1994.02a
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    • pp.412-415
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    • 1994
  • The fundamental assumption that thresholds exist for noncarcinogenic toxic effects of chemicals is reviewed; this assumption forms the basis for the no-observed-effect level/ safety-factor (NOEL/SF) approach to risk assessment for such effects. The origin and evolution of the NOEL/SF approach are traced, and its limitations are discussed. The recently proposed use of dose-response modeling to estimate a benchmark dose as a replacement for the NOEL is explained. The possibility of expanding dose-response modeling of non carcinogenic effects to include the estimation of assumed thresholds is discussed. A new method for conversion of quantitative toxic responses to a probability scale for risk assessment via dose-response modeling is outlined.

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A Theoretical Calculation of Photon Dose Equivalent Conversion Factor For Extremity Dosimeter (말단선량계의 광자선량당량환산인자에 대한 이론적 계산)

  • Kim, Kwang-Pyo;Lee, Won-Keun;Kim, Jong-Su;Yoon, Yeo-Chang;Yoon, Suk-Chul
    • Journal of Radiation Protection and Research
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    • v.21 no.1
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    • pp.41-50
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    • 1996
  • In this study, the theoretical calculation of the air kerma-to-dose equivalent conversion factors was performed with a Monte Carlo N-Particle transport code for the two types of extremity phantom of the ANSI and the KAERI, respectively. Considering the distribution of absorbed dose due to the interaction of homogeneous Parallel broad beam of monoenergetic primary photons in the range between 15keV and 1.5MeV, the air kerma-to-dose equivalent conversion factors based on the kerma approximation were calculated. It is showed that all the theoretical conversion factors of the two types of the extremity phantom for the ANSI and the KAERI agree well with the experimental values of the ANSI N13.32 draft(1995) for each energy within 5.7%, maximum difference ratio, except for 13.6%, difference ratio in the case for the energy of less than 40keV. It is due to uncertainties of experiment occurred in the low X-ray energy range and geometry considered in the MCNP code.

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Biosphere Modeling for Dose Assessment of HLW Repository: Development of ACBIO (고준위 방사성패기물 처분장 생태계 모델링을 위한 ACBIO개발)

  • Lee, Youn-Myoung;Hwang, Yong-Soo
    • Journal of Nuclear Fuel Cycle and Waste Technology(JNFCWT)
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    • v.6 no.2
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    • pp.73-100
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    • 2008
  • For the purpose of evaluating dose rate to individual due to long-term release of nuclides from the HLW repository, a biosphere assessment model and the implemented code, ACBIO, based on BIOMASS methodology have been developed by utilizing AMBER, a general compartment modeling tool. To show its practicability and usability as well as to see the sensitivity of compartment scheme or parametric variation to concentration and activity in compartments as well as annual flux between compartments at their peak values, some calculations are made and investigated: For each case when changing the structure of compartments and GBIs as well as varying selected input Kd values, all of which seem very important among others, dose rate per nuclide release rate is separately calculated and analyzed. From the maximum dose rates (Bq/y), flux-to-dose conversion factors (Sv/Bq) for each nuclide were derived, which are to be used for converting the nuclide release rate appearing from the geosphere through various GBIs to dose rate (Sv/y) for individual in critical group. It has been also observed that compartment scheme, identification of possible exposure group and GBIs could be all highly sensitive to the final consequences in biosphere modeling.

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Organ Dose Conversion Coefficients Calculated for Korean Pediatric and Adult Voxel Phantoms Exposed to External Photon Fields

  • Lee, Choonsik;Yeom, Yeon Soo;Griffin, Keith;Lee, Choonik;Lee, Ae-Kyoung;Choi, Hyung-do
    • Journal of Radiation Protection and Research
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    • v.45 no.2
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    • pp.69-75
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    • 2020
  • Background: Dose conversion coefficients (DCCs) have been commonly used to estimate radiation-dose absorption by human organs based on physical measurements of fluence or kerma. The International Commission on Radiological Protection (ICRP) has reported a library of DCCs, but few studies have been conducted on their applicability to non-Caucasian populations. In the present study, we collected a total of 8 Korean pediatric and adult voxel phantoms to calculate the organ DCCs for idealized external photon-irradiation geometries. Materials and Methods: We adopted one pediatric female phantom (ETRI Child), two adult female phantoms (KORWOMAN and HDRK Female), and five adult male phantoms (KORMAN, ETRI Man, KTMAN1, KTMAN2, and HDRK Man). A general-purpose Monte Carlo radiation transport code, MCNPX2.7 (Monte Carlo N-Particle Transport extended version 2.7), was employed to calculate the DCCs for 13 major radiosensitive organs in six irradiation geometries (anteroposterior, posteroanterior, right lateral, left lateral, rotational, and isotropic) and 33 photon energy bins (0.01-20 MeV). Results and Discussion: The DCCs for major radiosensitive organs (e.g., lungs and colon) in anteroposterior geometry agreed reasonably well across the 8 Korean phantoms, whereas those for deep-seated organs (e.g., gonads) varied significantly. The DCCs of the child phantom were greater than those of the adult phantoms. A comparison with the ICRP Publication 116 data showed reasonable agreements with the Korean phantom-based data. The variations in organ DCCs were well explained using the distribution of organ depths from the phantom surface. Conclusion: A library of dose conversion coefficients for major radiosensitive organs in a series of pediatric and adult Korean voxel phantoms was established and compared with the reference data from the ICRP. This comparison showed that our Korean phantom-based data agrees reasonably with the ICRP reference data.