• Title/Summary/Keyword: dose change

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Insights from an OKMC simulation of dose rate effects on the irradiated microstructure of RPV model alloys

  • Jianyang Li;Chonghong Zhang;Ignacio Martin-Bragado;Yitao Yang;Tieshan Wang
    • Nuclear Engineering and Technology
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    • v.55 no.3
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    • pp.958-967
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    • 2023
  • This work studies the defect features in a dilute FeMnNi alloy by an Object Kinetic Monte Carlo (OKMC) model based on the "grey-alloy" method. The dose rate effect is studied at 573 K in a wide range of dose rates from 10-8 to 10-4 displacement per atom (dpa)/s and demonstrates that the density of defect clusters rises while the average size of defect clusters decreases with increasing dose rate. However, the dose-rate effect decreases with increasing irradiation dose. The model considered two realistic mechanisms for producing <100>-type self-interstitial atom (SIA) loops and gave reasonable production ratios compared with experimental results. Our simulation shows that the proportion of <100>-type SIA loops could change obviously with the dose rate, influencing hardening prediction for various dose rates irradiation. We also investigated ways to compensate for the dose rate effect. The simulation results verified that about a 100 K temperature shift at a high dose rate of 1×10-4 dpa/s could produce similar irradiation microstructures to a lower dose rate of 1×10-7 dpa/s irradiation, including matrix defects and deduced solute migration events. The work brings new insight into the OKMC modeling and the dose rate effect of the Fe-based alloys.

The investigation of the exposure dose reduction of the Staff according to the Lead Curtain installation in EVAR(Endovascular Aneurysm Repair) surgical operation using C-arm (C-arm을 이용한 EVAR(Endovascular Aneurysm Repair) 시술시 Lead Curtain 설치에 따른 Staff의 피폭선량 감소에 대한 연구)

  • Yoo, In Woung;Chung, Jea Yeon;Lee, Kwan Seob
    • Korean Journal of Digital Imaging in Medicine
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    • v.14 no.2
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    • pp.33-38
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    • 2012
  • In EVAR procedure using long time C-arm, we studied exposure dose reduction and effeciency through measuring surgical staff's ESD by installing lead curtain operating table next to. The height 3 the spot (50cm, 100cm, 150cm) dose was measured on 2 locations for 600sec in the X-ray radiation considering the surgical staff's movement. To install the curtains, we compared before and after the dose. As a result, it can confirm that dose of the installation former of 50cm height and after is reduced about 75% and 91% in 2 locations. In 100cm height, the reduction of the dose was a bit confirmed. There as to dose value, measured on 150cm height the installation former and after was nearly no change. This research examined the exposure dose about the radiation of the surgical staff during EVAR procedure in which the operation time is the long time. It was implemented in the object that it reduces the radiation exposure. It could confirm the certain effect of the experimental result exposure dose reduction In EVAR procedure using long time C-arm, we studied exposure dose reduction and effeciency through measuring surgical staff's ESD by installing lead curtain operating table next to. The height 3 the spot (50cm, 100cm, 150cm) dose was measured on 2 locations for 600sec in the X-ray radiation considering the surgical staff's movement. To install the curtains, we compared before and after the dose. As a result, it can confirm that dose of the installation former of 50cm height and after is reduced about 75% and 91% in 2 locations. In 100cm height, the reduction of the dose was a bit confirmed. There as to dose value, measured on 150cm height the installation former and after was nearly no change. This research examined the exposure dose about the radiation of the surgical staff during EVAR procedure in which the operation time is the long time. It was implemented in the object that it reduces the radiation exposure. It could confirm the certain effect of the experimental result exposure dose reduction.

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Studies on Digitalis Receptor Desensitization in Rat Ventricle

  • Lee, Shin-Woong-;Jang, Tae-Soo
    • Proceedings of the Korean Society of Applied Pharmacology
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    • 1994.04a
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    • pp.301-301
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    • 1994
  • $^3$H〕Ouabain binding parameters(K$\_$D/ and B$\_$max/,) in homogenates prepared fpom control rat ventricular strip and Langendorff preparations which were not previously exposed to ouabain were compared to those in homogenates from ventricular strip and Langendorff preparations that had been first exposed to a complete ouabain dose-response curve(10$\^$-7/M to 10$\^$-4/ M). In rat ventricular strips and Langendorff perfused rat heart preparations, cumulative dose-response cruves of ouabain revealed biphasic positive inotropic effects, a "low-dose" and a "high-dose" effect with ED$\_$50/ values of 0.5${\mu}$M and 35${\mu}$M ouabain, respectively- The "low-dose" effect in rat ventricular strips disappeared or was diminished significantly when the ouabain dose-response curve wag repeated after the washout of the effects of the first curve, whereas the maximal "high-dose" effect was identical in both exposures to oubain. However, there was no change in the "low-dose" effects in both sets of the Langendorff perfused hearts. The contractile activity of the pre-exposed strips did not indicate the presence of residual ouabain since their basal contractile force was decreased 10% compared to initial control. 〔$^3$H〕Ouabain binding parameters, K$\_$D/ and B$\_$max/, were not changed comparing homogenate of control ventricular strips with that of strips pre-exposed to ouabain. These results suggest that digitalis receptor desensitization in the rat ventricular strip may due to the change of post-receptor events induced by ouabain binding to a high affinity site(${\alpha}$$_2$ isoform).

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Long-term Outcomes of Gamma Knife Stereotactic Radiosurgery of Vestibular Schwannomas

  • Kim, Kang-Min;Park, Chul-Kee;Chung, Hyun-Tai;Paek, Sun-Ha;Jung, Hee-Won;Kim, Dong-Gyu
    • Journal of Korean Neurosurgical Society
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    • v.42 no.4
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    • pp.286-292
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    • 2007
  • Objective : Gamma Knife Stereotactic Radiosurgery (GK SRS) has become an important treatment modality for vestibular schwannomas. We evaluated the tumor control rate, patterns of tumor volume change and preservation of hearing following low-dose radiation for vestibular schwannomas in a homogeneous cohort group in which the mean marginal dose was 12 Gy. Methods : A total of 59 patients were enrolled in this study. All enrolled patients were followed-up for at least 5 years and the radiation dose was 11-13 Gy. Regular MRI, audiometry and clinical evaluations were done and tumor volumes were obtained from MRI using the OSIRIS program. Results : The tumor control rate was 97%. We were able to classify the patterns of change in tumor volume into three categories. Transient increases in tumor volume were detected in 29% of the patients and the maximum transient increase in tumor volume was identified at 6 to 30 months after GK SRS. The transient increases in tumor volume ranged from 121% to 188%. Hearing was preserved in 4 of the 12 patients who had serviceable hearing prior to treatment. There were no other complications associated with GK SRS. Conclusion : Low-dose GK SRS was an effective and safe mode of treatment for vestibular schwannomas in comparison to the previously used high-dose GK SRS. Transient increases in tumor volume can be identified during the follow-up period after low-dose GK SRS for vestibular schwannomas. Physicians should be aware that these increases are not always indicative of treatment failure and that close observation is required following treatments. Unfortunately, a satisfactory hearing preservation rate was not achieved by reducing the radiation dose. It is thought that hearing preservation is a more sophisticated problem and further research is required.

A Study on the Quantitative Analysis Method through the Absorbed Dose and the Histogram in the Performance Evaluation of the Detector according to the Sensitivity Change of Auto Exposure Control(AEC) in DR(Digital Radiography) (DR(Digital Radiography)에서 자동노출제어장치의 감도변화에 따른 검출기 성능평가 시 흡수선량과 히스토그램을 통한 정량적 분석방법에 관한 연구)

  • Hwang, Jun-Ho;Lee, Kyung-Bae
    • The Journal of the Korea Contents Association
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    • v.18 no.1
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    • pp.232-240
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    • 2018
  • This study is to suggest a method to evaluate the detector performance using change of absorbed dose and histogram according to sensitivity change of Auto Exposure Control(AEC). The experiment site is skull, abdomen pelvis and the accuracy of the detector was evaluated by measuring the absorbed dose of the detector sensitivity S200, S400, S800, S1000. Also the dynamic range of the detector was evaluated through the histogram analysis. As a result, the absorbed dose decreased gradually as the sensitivity was set higher from S200 to S1000. And through the sensitivity histogram analysis, as the sensitivity of the skull is set higher, the amount of information at both ends of the histogram is lost. Abdomen and pelvis areas showed underflow phenomena in which the amount of information in the first part of the histogram was lost as the sensitivity was set higher. In conclusion, the detector accurately implemented the sensitivity change, but the dynamic range of the image due to the sensitivity change of the AEC due to the deterioration of the detector performance can not be realized properly and it was found that the evaluation through the absorbed dose and the histogram is useful when evaluating the performance of the detector.

Changes in Image Quality and Dose according to Exposure Parameters of Brain CT (두부 CT의 노출 파라메타에 따른 화질과 선량의 변화)

  • Choi, Seok yoon;Im, In Chul
    • Journal of the Korean Society of Radiology
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    • v.13 no.5
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    • pp.705-711
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    • 2019
  • Currently, the brain CT scan of the latest equipment lacks the study of parameter change and dose change and especially of noise, uniformity analysis and dose change. Therefore, this study attempted to study the phenomenon that occurs at this time by analyzing tube voltage, slice thickness, and pitch change in exposure parameters when using high specification CT. Experimental results show that uniformity is better when using high voltage, thick slice thickness selection, and minimum pitch. As a result of the combination, the most uniformity condition was 140 kVp, 10 mm and pitch 0.5. Noise was found to be improved regardless of pitch by increasing tube voltage and slice thickness. The radiation dose increased linearly with tube voltage and pitch. Therefore, the results of this study will serve as a reference for the use of High specification brain CT.

Evaluation for the Usefulness of Copper Filters according to Mode Change in Digital Radiography System (DR 시스템에서 모드 변화에 따른 구리필터의 유용성 평가)

  • Kim, Jae-Kyeom;Kim, Jeong-Koo
    • Journal of radiological science and technology
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    • v.44 no.1
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    • pp.39-46
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    • 2021
  • This study confirmed the usefulness of the copper filter according to the mode change by comparing and analyzing the energy change according to the application of the copper filter and the change in effective dose and image quality according to the distance to the subject in the DR(Digital Radiography) system. The average energy increased when the copper filter was applied and the reduction rate by 50% of mAs was increased as the thickness of the copper filter increased according to the application of the 10 kVp rule in AEC mode. The effective dose decreased as the thickness increased when the copper filter was applied in AEC(Automatic Exposure Control) mode and manual mode according to the application of the 10 kVp rule, and the decrease rate decreased with increasing 10 kVp increments. As a result of analyzing the dicom images for AEC mode and manual mode with Image J. the PSNR(Peak Signal to Noise Ratio) values were approximate values of less than 30 dB for each mode and for each copper filter thickness. When the copper filter was applied, the average energy increased, so when the 10 kVp rule was applied, the mAs for each mode could be reduced, and the effective dose could also be reduced. However, as the distance and tube voltage increased, the reduction rate of mAs decreased, and the quality of the image was found to decrease when the copper filter was applied, but there was no difference in quality of the image when the copper filter thickness increased.

The Effect of Photoneutron Dose in High Energy Radiotherapy (10 MV 이상 고에너지 치료 시 발생되는 광중성자의 영향)

  • Park, Byoung Suk;Ahn, Jong Ho;Kwon, Dong Yeol;Seo, Jeong Min;Song, Ki Weon
    • The Journal of Korean Society for Radiation Therapy
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    • v.25 no.1
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    • pp.9-14
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    • 2013
  • Purpose: High-energy radiotherapy with 10 MV or higher develops photoneutron through photonuclear reaction. Photoneutron has higher radiation weighting factor than X-ray, thus low dose can greatly affect the human body. An accurate dosimetric calculation and consultation are needed. This study compared and analyzed the dose change of photoneutron in terms of space according to the size of photon beam energy and treatment methods. Materials and Methods: To measure the dose change of photoneutron by the size of photon beam energy, patients with the same therapy area were recruited and conventional plans with 10 MV and 15 MV were each made. To measure the difference between the two treatment methods, 10 MV conventional plan and 10 MV IMRT plan was made. A detector was placed at the point which was 100 cm away from the photon beam isocenter, which was placed in the center of $^3He$ proportional counter, and the photoneutron dose was measured. $^3He$ proportional counter was placed 50 cm longitudinally superior to and inferior to the couch with the central point as the standard to measure the dose change by position changes. A commercial program was used for dose change analysis. Results: The average integral dose by energy size was $220.27{\mu}Sv$ and $526.61{\mu}Sv$ in 10 MV and 15 MV conventional RT, respectively. The average dose increased 2.39 times in 15 MV conventional RT. The average photoneutron integral dose in conventional RT and IMRT with the same energy was $220.27{\mu}Sv$ and $308.27{\mu}Sv$ each; the dose in IMRT increased 1.40 times. The average photoneutron integral dose by measurement location resulted significantly higher in point 2 than 3 in conventional RT, 7.1% higher in 10 MV, and 3.0% higher in 15 MV. Conclusion: When high energy radiotherapy, it should consider energy selection, treatment method and patient position to reduce unnecessary dose by photoneutron. Also, the dose data of photoneutron needs to be systematized to find methods to apply computerization programs. This is considered to decrease secondary cancer probabilities and side effects due to radiation therapy and to minimize unnecessary dose for the patients.

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Indicator microorganisms concentrations change after irrigation of wastewater treatment effluent in paddy field for water reuse (용수 재이용을 위한 하수처리수 관개 후 논에서의 지표성 미생물의 거동)

  • Jung, Kwang-Wook;Yoon, Chun-G.
    • Proceedings of the Korean Society of Agricultural Engineers Conference
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    • 2003.10a
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    • pp.583-586
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    • 2003
  • The objective of this research was to examine the significance of change to indicator microorganisms (TC, FC, and E. coli) in the paddy field and repair of UV disinfected secondary effluent. Average concentrations of Microorganisms were maintained by more than about 1,000 MPN/100mL in paddy field after irrigation. Microorganism repair was evaluated in relation to UV dose in photoreactivating light and dark. In addition, a significant inverse relationship was found between UV dose and repair of indicator microorganisms when the research of wastewater was conducted in the condition of low and high UV dose.

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APPLICATION OF ALANINE/ESR SPECTRUM SHAPE CHANGE IN GAMMA DOSIMETRY

  • Choi, Hoon;Kim, Jeong-In;Lee, Byung-Ill;Lim, Young-Ki
    • Nuclear Engineering and Technology
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    • v.42 no.3
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    • pp.313-318
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    • 2010
  • Alnine pellets were installed in a nuclear power plant for one or two operation cycles and measured by electron spin resonance (ESR) spectrometers for dosimetry. Dose and "x/y ratio", i.e., satellite peak over main center peak ratio, were measured for the returned alanine dosimeters from the nuclear power plant and compared to the values of reference alanine dosimeters exposed only to gamma rays. The variation of the x/y ratio change depended on the population of radicals from each radiation component with different LET. The gamma dose in a mixed radiation field was estimated by an additive gamma ray irradiation experiment and the measured dose rate at specified locations in the containment building.