• Korean Journal of Veterinary Research
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• v.47 no.2
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• pp.197-202
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• 2007

This experiment has been investigated in order to examine larval migration inhibition activity of ivermectin, doramectin and ethanol against Anisakis simplex (A. simplex) in vitro. A. simplex larvae were obtained from the mackerel acquired from the fish market of Cheongju. They were divided into many groups and placed in culture dishes (40 larvae each) containing RPMI-1640, in the absence or presence of different concentrations of ivermectin, doramectin and ethanol. Ivermectin had a complete inhibition of larval migration at 72 h in all groups ($10-300{\mu}g/ml$). Ethanol reduced the migration of the larvae, its maximum activity being an high doses (7.5%, 10% ethanol) when it was 100% efficacy at 4 h. Doramectin had no efficacy in vitro. Being needed that further studies with ivermectin and doramectin, it is recommended that in vivo test with laboratory animals should be carried.

• Korean Journal of Veterinary Service
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• v.31 no.1
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• pp.93-100
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• 2008

This experiment has been investigated in order to examine the effect of ivermectin and doramectin for laval migratory inhibition in rats. Anisakis spp larvae were obtained from the mackerels in fish market in Cheongju. A total of 225 rats were classified with 3 groups with the same number ($3{\times}75$ rats); group I was control divided into 3 subgroups including 25 rats in each one, others (test groups) were treated subcutaneously with ivermectin and doramectin by 3 kinds of concentrations ($200{\mu}g/kg$, 400, 800), respectively. At 15 minutes after treating, 10 larvae were taken orally into each rat of 6 subgroups in test, and 5 rats were necropsied at 0.5, 1, 2, 4 and 8 hours after oral administration. The recovered larvae were used in larval migration inhibition (LMI). Ivermectin is significantly more effective than doramectin. In rats, the inhibitory effect of ivermectin and doramectin is slightly less than in vitro.

• Journal of the korean veterinary medical association
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• v.33 no.12
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• pp.743-748
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• 1997

Doramectin(DECTOMAXR), 25-cyclohexyl avermectin, which has acaricidal and anthelmintic effect was evaluated against the natural infestations of Sarcoptes scabiei var suis and GI nematodes(Ascaris suum and Trichuris suis) as measured by litter size and wei

• Proceedings of the Korean Society of Veterinary Clinics Conference
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• 2007.05a
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• pp.124-124
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• 2007

• Journal of Veterinary Clinics
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• v.37 no.2
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• pp.96-99
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• 2020

An 11-year-old female Yorkshire terrier presented with alopecia, hyperpigmentation, and pruritus. Dermatological examination revealed a large number of Demodex mites including D. cornei and D. canis. Mean length of total body length of D. cornei was one third shorter than that of D. canis. In addition, sequential analysis of DNA extracted from the skin lesions showed a 97% and 99% identity with the two sequences of D. canis and D. cornei. This is the first report of a combined infestation of D. cornei and D. canis in Korea, along with its morphological and molecular characterization.