• Journal of Sasang Constitutional Medicine
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• v.8 no.1
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• pp.337-347
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• 1996

The 73 outpatients who had been treated in the Oriental Medical Hospital at Dong Eui Medical Center have participated in this study. The following conclusions were made in comparison with the type of disease and symptom and sasang constitution classification. (in the field of questionnaire analysis) 1. The symptom of "weight loss" is significant differences in sasang constitution classification. The frequency of Taeeum goup is more than Soyang group and Soeum group. 2. The symptom of "vomitig" is significant differences in sasang constitution classification. The frequency of Taeeum goup is more than Soyang group and Soeum group. 3. The symptom of "hoarseness" is significant differences in sasang constitution classification. The frequency of Soeum goup is more than Soyang group and Taeeum group. 4. The symptom of "respiratory distress" is significant differences in sasang constitution classification. The frequency of Taeeum goup is more than Soyang group and Soeum group. 5. The symptom of "arthralgia" is significant differences in sasang constitution classification. The frequency of Soyang goup is more than Taeeum group and Soeum group. 6. The symptom of "menstrual pain" is significant differences in sasang constitution classification. The frequency of Soeum goup is more than Soyang group and Taeeum group. 7. The analysis of past history and sasang constitution classification didn't show any significant differences. Only the analysis of past history and age show significant differences. I think that it is necessary to go deep into the clinical study of the type of disease and symptom according to sasang constitution classification.

• International Journal of Highway Engineering
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• v.10 no.1
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• pp.75-85
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• 2008

Moisture damage of asphalt mixtures can occur because of a loss of bond between the asphalt binder and the fine and coarse aggregates. Therefore, moisture damage on asphalt pavements is the main cause of potholes, which is one of the main distress type of asphalt pavement. The purpose of this study is to evaluation effect moisture damage on material properties of asphalt mixtures through the laboratory performance test. The existing Modified Lottman test procedure was improved and the number of times that thermal cyclic conditioning can be added until the asphalt mixtures is damaged, was tested in order to exhibit the changes of the material properties because of moisture damage by immersion. Through the above experiments, it was found that the material properties of asphalt mixtures on room-temperature were rapidly decreased with loss of about 50% at initial stage of moisture damage caused by the amount of repeated immersion. Also, it was found that the property damage ratio using material properties of failure energy and $DCSE_f$ by test temperature $25^{\circ}C$ were showed a high relationship to moisture damage of the asphalt mixtures caused by the amount of repeated immersion.

• Journal of Society of Preventive Korean Medicine
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• v.17 no.3
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• pp.129-141
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• 2013

Objectives : Anorexia is the primary symptom impinging cancer patients' Quality of Life. It is usually accompanied by gastrointestinal symptoms(GI symptoms). Thus, to measure anorexia symptom precisely, assessing anorexia and GI symptoms together is recommended. This study was designed to analyze cancer-related anorexia assessment tools, extract GI symptoms included in these tools and investigate usefulness of instruments in clinical trials. Methods : Instruments were selected by searching PubMed, PROQOLID database. We analyzed instruments by number of items, assessment method, type of question, GI symptoms. Results : 9 instruments were selected to assess cancer-related anorexia symptom. Most tools adopt Likert scale as response scale and 'during past week' as recall period. Assessment method of all 9 instruments is the self-administration. Questions measuring anorexia are able to be sorted into 3 forms (frequency, severeness, distress of anorexia symptom). Among the GI symptoms, nausea is included in all 9 instruments. In clinical trials of cancer-related anorexia, Edmonton Symptom Assessment Scale(ESAS) and Functional Assessment of Anorexia/Cachexia Therapy Questionnaire(FAACT) were selected as endpoint measure. Conclusions : The result showed that FAACT is the only specialized tool to assess cancer-related anorexia. To measure cancer-related anorexia precisely, the need to develop new instrument exists.

• Advances in pediatric surgery
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• v.1 no.2
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• pp.133-139
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• 1995

Because rectal prolapse in pediatric age was known to have a self-limitting natural history in weeks to years, this disease is prone to be regarded as a minor condition to the most of surgeons. But to the children and the parents who have to be suffered each time could be a heavy distress. Even though operative or nonoperative methods can be applicable for treatment, the main problem is in surgeon's side, whose preference is based on the experiences of adult patients. The authors have experienced 16 cases of ano-rectal prolapse for 9 years since 1986. Eleven of them were true rectal prolapses. In 7 cases of true type, injection therapy has been tried. One ml of five percent phenol in glycerine was injected into the submucosal layer of the ano-rectal angle level at both lateral and posterior sides. After first trial of each cases, 5 of them were cured completely so far. Recurrences were in two cases, but one of them was temporary to be subsided afterward. Complete bowel cleansing and adequate sedations were required as preoperative preparations. Two days' oral antibiotics and two weeks' laxatives for free of defecation straining were recommended after the procedure. The safety of sclerosis was supported by the experimental histology. In pediatric rectal prolapse, sclerosis seems to be a safe and effective treatment of choice without any significant morbidity.

• Journal of Advanced Marine Engineering and Technology
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• v.41 no.1
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• pp.111-117
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• 2017

The arrival time of rescue ships is very important in the event of distress. This paper presents the development of experimental data to calculate the arrival time of rescue ships. The ship's traffic probability distribution was used. Mokpo Port was selected as the area of study, and AIS data for a 1 year period were used. For the ship's traffic probability distribution, a gateline was established. The lateral range distribution was calculated and fitted to the normal distribution and two Gaussian mixture distributions (GMD2), and each parameter was extracted. After the locations of ${\mu}$, ${\mu}{\pm}1{\sigma}$ of the normal distribution and ${\mu}_1$ of the two Gaussian mixture distribution(GMD2) were set as waypoints, the location and probability were determined. A scenario was established in relation to each type of parameter. Thus, the arrival time can be calculated.

• Biomolecules & Therapeutics
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• v.5 no.2
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• pp.133-149
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• 1997

4-week repeated dose toxicity of DA-5018, a new capsaicin analogue analgesic agent, was examined in 5D rats at dosage levels of 0,0.4,2, 10 and 50 mg/kg/day. DA-5018 was administered orally to 17 males and 17 females per group at doses of 0, 10 and 50 mg/kg and to 12 males and 12 females per group at doses of 0.4 and 2 mg/kg. After the administration period, 5 males and 5 females at the 0, 10 and 50 mg/kg were placed on withdrawal for 2 weeks. Treatment-related clinical signs were observed at 10 and 50 mg/kg. Clinical signs observed immediately after the administration of DA-5018 were grooming, sedation or depression, lacrimation, atacia, reddening of extremities and ears, ventral or lateral recumvincy, respiratory distress, cyanosis and convulsion. Delayed-type clinical signs including focal scabbing and depilation around nose were also observed 1 or 2 weeks after the start of administration of DA-5018. Only at the 50 mg/kg group, corneal opacities, reduced body weight gain (male) and death (male 6/17, female 3/17) were noted. In blood biochemical analysis, serum levels of glucose and triglyceride decreased at 10 and 50 mg/kg. In hematological examination, there were increases in the number of red blood cell, hemoglobin content and percent of hematocrit at 10 and 50 mg/kg. Pulmonary enlargement and hemorrhagic spot, focal scabbing and depilation around nose and corneal opacities were seen at the necropsy of the animals died during the dosing of DA-5018 50 mg/kg. Focal scabbing and depilation around nose were observed in the animals terminally necropsied at doses of 10 and 50 mg/kg. Histopathological examination revealed pulmonary hemorrhage, focal necrosis in the scabbed area, corneal necrosis, fibrosis and neovasculization in the stroma. At 0.4 and 2 mg/kg, there were no significant toxic changes attributable to the administration of DA-5018. In conclusion, target organs following to 4-week repeated dose of DA-5018 in the rat were determined to be lung, skin and eyes. Definite toxic dose and no-observed-adverse-effect-level (NOAEL) were estimated to be 50 and 2 mg/kg/day, respectively.

• Journal of Veterinary Clinics
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• v.32 no.5
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• pp.454-458
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• 2015

This report describes the diagnostic radiographic and CT features of pleuropneumonia in a cat with wet type of feline infectious peritonitis (FIP). In a 1 year-old cat presented with respiratory distress, pulmonary mass, thickened pleural wall with mass-like structures, and a large amount of pleural effusion were identified on radiography, ultrasonography, and CT. About two months later, in addition to the pre-existing lesions, multiple nodules had developed on the intestine and left kidney. The cat was diagnosed with pleuropneumonia caused by FIP through histologic examination and immunohistochemistry. Pleuropneumonia is rarely reported in cats with FIP, and only one cat with non-effusive FIP had pyogranulomatous pneumonia as consolidated lung lobe. In the present case, pleuropneumonia was detected as multiple mass-like lesions on diagnostic imaging.

• Korean Journal of Veterinary Research
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• v.50 no.4
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• pp.265-271
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• 2010

Post-weaning multisystemic wasting syndrome (PMWS) is a new emerging disease affecting nursery and growing pigs in worldwide. Porcine circovirus type 2 (PCV-2) is a most important pathogen associated with PMWS. This study was carried out to investigate the pathological changes in the pancreas of pigs diagnosed as PMWS. To detect the PCV-2 antigen and nucleic acid in the tissue, immunohistochemistry and polymerase chain reaction (PCR) was conducted, respectively. 24 pigs of 4-10 weeks old showed clinical signs of PMWS such as chronic wasting, respiratory distress and diarrhea were examined. Histopathologically, interstitial and periductular mononuclear cells infiltration were observed in pancreas. Multifocal to diffuse necrosis of acinar tissues or necrotizing to granulomatous pancreastitis with numerous syncytial cells infiltration were examined in severe cases. PCV-2 nucleic acid was detected from all tested pancreas using PCR. The PCV-2 antigen in 12 pancreas sections was detected by immunohistochemical staining. PCV-2 has a tropism for vascular endothelial cells and infiltrated macrophages. Although gross lesions are uncommon in the pancreas of pigs with PMWS, histopathological changes and the presence of PCV-2 in this tissue may be related to clinical signs associated with digestive disorders.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.1
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• pp.544-554
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• 2015

This study was performed to determine the factors related to suicide ideation among some middle school students. A self-administered questionnaires survey was administered to 975 middle school students in Gyeongin area during the period from May 1st to June 30th, 2013. As a result, the suicide ideation of respondents turned out to be significantly higher in the following groups: females, experience of smoking, experience of alcohol drinking, of which the self-recognized body type was fatty, with out regular eating, poor subjective health status, poor home atmosphere, low family life satisfaction, lower school grade, poor relationship with friends, school violence experienced, school life dissatisfaction, severe hopelessness, severe distress, and depression. In particular, the factors related to hopelessness are strongly correlated with the suicide ideation.

• Archives of Craniofacial Surgery
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• v.21 no.5
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• pp.283-287
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• 2020

Background: Closed reduction is the standard treatment for nasal bone fractures, which are the most common type of facial bone fractures. We investigated the effect of closed reduction on quality of life. Methods: The 15-dimensional health-related quality of life survey was administered to 120 patients who underwent closed reduction under general anesthesia for nasal bone fractures from February 2018 to December 2019, on both the day after surgery and 3 months after surgery. Three months postoperatively, the presence or absence of five nasal symptoms (nose obstruction, snoring, pain, nasal secretions, and aesthetic dissatisfaction) was also evaluated. Results: The quality of life items that showed significant changes between immediately after surgery and 3 months postoperatively were breathing, sleeping, speech, excretion, and discomfort. Low scores were found at 3 months for breathing, sleeping, and distress. There were 31 patients (25.83%) with nose obstruction, 25 (20.83%) with snoring, 12 (10.00%), with pain, 11 (9.17%) with nasal secretions, and 29 (24.17%) with aesthetic dissatisfaction. Conclusion: Closed reduction affected patients' quality of life, although most aspects improved significantly after 3 months. However, it was not possible to rule out deterioration of quality of life due to complications and dissatisfaction after surgery.