• Title/Summary/Keyword: distant metastases

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Cervical lymph node metastasis form non-head & neck sites: below diaphragm (횡격막 아래 장기에서 발생한 악성 종양의 경부림프절 전이 사례 분석)

  • KIM, Jinil;SONG, Seulki;SEOK, Jungirl;LEE, Minhyung;HAN, Sung Jun;JUNG, Young Ho;AHN, Soon Hyun;JEONG, Woo-Jin
    • Korean Journal of Head & Neck Oncology
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    • v.34 no.2
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    • pp.17-21
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    • 2018
  • Background/Objectives: Cancers of the abdominal or pelvic organ rarely metastasize to the cervical lymph nodes. Although it indicates distant metastasis, perceivable prolongation of survival or cure may be possible in selected cases. We sought to identify patients with cervical metastasis from cancers below the diaphragm and identify patients who may benefit from aggressive treatment. Materials & Methods: From 2009 to 2017, patients with pathologically confirmed metastatic cervical lymph nodes originating from below the diaphragm were included for analysis. Patient demographics, cancer characteristics, treatment course, and clinical outcomes were analyzed. Results: 208 patients were identified. Left supraclavicular node (Virchow's node) was the most frequently involved. Irrespective of treatment, survival for uterine cervical and ovarian cancers was significantly longer than that of other primaries. Patients with isolated cervical metastasis (oligometastasis) had significantly longer median survival compared to patients with concomitant bone, lung, brain, and mediastinal metastases. Conclusion: Although cervical metastasis from cancers of the abdominal and pelvic organ represent distant metastasis, patients with uterine cervix and ovary primary and oligometastatic lesions may benefit from aggressive treatment. Prudent patient selection and further investigation is warranted.

Do Not Let to Be Late: Overview of Reasons for Melanoma Delayed Diagnosis

  • Gajda, Maksymilian;Kaminska-Winciorek, Grazyna
    • Asian Pacific Journal of Cancer Prevention
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    • v.15 no.9
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    • pp.3873-3877
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    • 2014
  • Melanoma of the skin is a malignant tumor, which incidence is still increasing. It was estimated that in the United States one person died from this cause every hour. The major risk factor of this disease is exposure to ultraviolet radiation, especially associated with the occurrence of sunburns. Patients diagnosed with distant metastases have median survival of 6-9 months. The aim of this paper was to identify the causes of delayed diagnosis of melanoma as diagnosis at an early stage seems to be the key to improve the survival rates. For this purpose, a search of medical databases such as PubMed, Google Scholar and Cancer Registers was conducted and an analysis of the literature from the years 1979-2013 was conducted.

Brain Metastasis of Renal Cell Carcinoma in Von Hippel-Lindau Disease - Case Report - (본 히펠 린다우병에서 발생한 신장암의 뇌전이 - 증례보고 -)

  • Yang, Seung Min;Park, Sang Woo;Suk, Jong Sik;Park, Jong Hyuk;Kwon, Jeong Taik;Min, Byung Kook
    • Journal of Korean Neurosurgical Society
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    • v.30 no.8
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    • pp.1019-1022
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    • 2001
  • Although brain metastasis of renal cell carcinoma is a major cause of death in Von Hippel-Lindau disease(VHL), it is not easy to distinguish local recurrence of hemangioblastoma from distant metastasis. In addition, hemangioblastoma has several characteristics suitable for recipient of "tumor-to-tumor metastasis". Authors report a case of Von Hippel-Lindau disease that had metastases of renal cell carcinomas.

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Intraventricular Atypical Meningiomas

  • Kim, Hyun-Doo;Choi, Chan-Young;Lee, Dong-Joon;Lee, Chae-Heuck
    • Journal of Korean Neurosurgical Society
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    • v.49 no.5
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    • pp.292-295
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    • 2011
  • A rare case of intraventricular meningioma that arose in the atrium of the left lateral ventricle was identified in a 51-year-old woman. Gross total removal was performed by transcortical approach. Histopathological findings showed meningothelial meningioma with a focal atypical area which had 8% of Ki-67 labeling index (LI). A large recurrence extending into the ipsilateral quadrigeminal cistern and opposite medial occipital lobe developed approximately 41 months after the first operation. The specimens obtained from the second resection showed atypical meningioma with 20% of Ki-67 LI but there were no anaplastic area. The patient underwent fractionated stereotactic radiotherapy. However, multiple local distant metastases were found in the occipital and cerebellar cortex suggesting cerebrospinal fluid dissemination apparently 24 months after the second operation. This report presents chronological progression of a rare intraventricular atypical meningioma with more aggressive transformation.

Total En Bloc Lumbar Spondylectomy of Follicular Thyroid Carcinoma

  • Jo, Dae-Jean;Jun, Jae-Kyun;Kim, Sung-Min
    • Journal of Korean Neurosurgical Society
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    • v.45 no.3
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    • pp.188-191
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    • 2009
  • The presence of distant metastases from differentiated thyroid carcinoma decreases the 10-year survival rates of patients by 50%. This is a report of a 61-year-old female with follicular thyroid carcinoma who presented initially with low back pain. 2-deoxy-2-[18F] fluoro-D-glucose whole-body positron emission tomography/computed tomography (PET/CT) demonstrated a hypointensity lesion in the left thyroid gland with malignant uptake in L1 vertebra and magnetic resonance images revealed paravertebral and epidural extension of mass in L1 vertebra. After thyroidectomy, histopathological study showed a follicular carcinoma. We performed L1 total en bloc spondylectomy with expandable cage for long-term local control. The technical details of total en bloc spondylectomy in follicular carcinoma are described herein.

The Value of Mediastinoscopy for Evaluation of Mediastinal Lymph Nodes in Bronchogenic Carcinoma : Accuracy of Mediastinoscopy (원발성 폐암에서 종격동 림프절 평가에 대한 종격동경 검사의 가치)

  • O, Sang-Jun;Kim, Chang-Ho
    • Journal of Chest Surgery
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    • v.24 no.8
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    • pp.751-756
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    • 1991
  • For the period from June 1988 to July 1991 we studied 29 patients who were judged to have operable disease before mediastinoscopy on clinical criteria[absence of distant metastases, phrenic or laryngeal nerve paralysis, positive scalene node biopsy, and malignant pleural effusion]. All patients had computed tomography and mediastinoscopy prior to operation. In the present study, the sensitivity, specificity, and accuracy of CT were 92%, 56%, and 72%, respectively. And the sensitivity, specificity, and accuracy of mediastinoscopy were 92%, 100%, and 97%, respectively. We concluded that because of the low accuracy of CT, CT cannot replace mediastinoscopy, and routine mediastinoscopy should be performed in preoperative staging of bronchogenic carcinoma.

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Malignant Fibrous Histiocytoma of the Heart A Case Report and Review of the Literature (심장내 악성 섬유성 조직구종)

  • 박종원
    • Journal of Chest Surgery
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    • v.22 no.2
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    • pp.297-304
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    • 1989
  • A 45-year old woman with congestive heart failure due to left atrial tumor was operated on. Three tumor masses arising from posterior wall, atrial septum, anterior portion of mitral valve were resected. Pathological diagnosis was malignant fibrous histiocytoma [MFH]. Above one case and sixteen previous reports are reviewed. Eleven cases out of 17 were females. The tumors all originated primarily in the left atrium and 8 had distant metastases. The metastatic sites are lung [4 cases], brain [2 cases], liver, jejunum, cervix and pleura etc. Careful pathologic study is necessary to differentiate the uniformly fatal MFH of the heart from the more common benign atrial myxoma. The treatment modalities are surgical resection, chemotherapy, and radiation therapy & the prognosis of intracardiac MFH is poor. We underwent partial resection of left atrial MFH and obtained symptom relief and patient still alive 7 months post-operatively in state of NYHA class II.

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Surgery for Primary Pulmonary Liposarcoma (원발성폐지방육종(Primary Pulmonary Liposarcoma)에 관한 수술치험 1예)

  • 김수완;김진국;김관민;최용수;안긍환;심영목
    • Journal of Chest Surgery
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    • v.37 no.11
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    • pp.942-945
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    • 2004
  • Primary pulmonary liposarcoma is extremely rare disease. It has poor prognosis with early multiple metastases and frequent local recurrences. Surgery is the choice of treatment for liposarcoma. Incomplete resection would result in rapid and aggressive growing of the tumor. We report a case of primary pulmonary liposarcoma which was successfully treated with complete resection without local recurrence and distant metastasis for 10 months.

A Case of Metastatic Renal Cell Carcinoma to Thyroid Gland (갑상선에 전이된 신세포암 1예)

  • Ko, Young-Bum;Park, Gi Cheol
    • Korean Journal of Head & Neck Oncology
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    • v.29 no.2
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    • pp.62-64
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    • 2013
  • The distant metastasis is found out in about 25-57% of the patients with renal cell carcinoma at the time of diagnosis. But, the incidence of metastases to the head and neck region, especially to the thyroid gland, is rare. Most of patients with metastatic renal cell carcinoma to the thyroid gland are asymptomatic at presentation as patients with primary thyroid carcinoma. In the presence of clear cell tumor of the thyroid gland, the diagnostic considerations must include metastatic renal cell carcinoma. We report a case of thyroid metastasis from renal cell carcinoma at the time of diagnosis.

Primary Merkel cell carcinoma of the earlobe in a young healthy man

  • Ha, Non Hyeon;Kim, Sue Kyung;Shin, Yoo Seob;Kim, Sue Min
    • Archives of Craniofacial Surgery
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    • v.19 no.3
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    • pp.205-209
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    • 2018
  • Merkel cell carcinoma (MCC) is an uncommon neuroendocrine cutaneous tumor with poor prognosis. It has the high rate of recurrence, mortality, regional nodal involvement, and distant metastases. It is difficult to diagnose MCC because of its non-specific clinical findings. It usually occurs on sun-exposed areas of the skin, mostly at head and neck. There is a difference in the incidence and prognosis according to site in the head and neck. However, there is no consented site-specific diagnosis, treatment or follow-up protocol for MCC at the head and neck. We herein report a case of MCC arising in the right earlobe of an otherwise healthy young man who has been diagnosed early, thereby successfully treated. With our closed follow-up, there was no tumor recurrence or complication at 33 months after diagnosis.