• Title/Summary/Keyword: disease outbreaks

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Outbreaks of mumps: an observational study over two decades in a single hospital in Korea

  • Ryu, Ji-Ung;Kim, Eun-Kyung;Youn, You-Sook;Rhim, Jung-Woo;Lee, Kyung-Yil
    • Clinical and Experimental Pediatrics
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    • v.57 no.9
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    • pp.396-402
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    • 2014
  • Purpose: The introduction of the mumps vaccine has dramatically reduced the number of mumps cases, but outbreaks have recently occurred among highly vaccinated populations in developed countries. Epidemiological and clinical characteristics of patients with mumps admitted between 1989 and 2012 in a single hospital in Korea are described in the present study. Methods: We retrospectively evaluated inpatients with mumps between 1989 and 2012 and outpatients and inpatients with mumps in 2011-2012. Results: A total of 152 patients with mumps were admitted between 1989 and 2012, and 163 patients were recorded in 2011-2012. The highest number of admitted cases occurred in 1998 and 2012 (35 and 34 cases, respectively). Among the patients admitted in 2011-2012, the highest frequency was observed among people aged 15-19 years, and low frequency was observed in those aged <4 years and >20 years, compatible to the city data and national data. In patients admitted to our department in 1998 (35 cases) and in 2010-2012 (27 cases), there were significant differences in the mean age and the rate of secondary measles-mumps-rubella (MMR) vaccination, but had similar clinical features, including complications, except aseptic meningitis. Antimumps immunoglobulin (Ig) G was positive in 83% and 100%, and IgM was positive in 67% and 41%, respectively, in the two periods. Conclusion: In Korea, recent mumps outbreaks have occurred mainly among secondary school students who received two doses of the MMR vaccine. The vaccinees might have a modified immune reaction to viral insults, manifesting modified epidemiological and clinical features.

Enterotoxin Production and DNA Fingerprinting of Staphylococcus aureus Isolated from Diverse Samples by Pulsed-Field Gel Electrophoresis

  • Suh, Dong-Kyun
    • Biomedical Science Letters
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    • v.11 no.3
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    • pp.295-299
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    • 2005
  • Staphylococcus aureus is an important animal and human pathogen implicated in a variety of disease including food-poisoning caused by staphyloccal enterotoxins (SEs). In order to investigate the difference in genomic types and to monitor the transmission of S. aureus isolates, a total of 25 S. aureus isolates from different sources were determined for their genotypic characteristics by pulsed-field gel electrophoresis (PFGE) in addition to their ability to enterotoxin production and antibiotic resistance patterns in this study. All the isolates were susceptible to amikacin, and the resistance pattern to ampicillin and penicillin were most common among 14 different patterns. Eleven of 24 isolates produced one of three SEs, SEA, SEC or SED. Sixteen representative PFGE patterns were obtained by Smal restriction fragments of S. aureus isolates. Analysis of dendrogram based on PFGE band patterns suggested that food-poisoning outbreaks be caused by the diverse sources of food, of which their raw materials were infected with S. aureus. Also, it could be concluded that PFGE was a powerful tool for epidemiological tracing of infection source for food-initiated outbreaks.

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Crisis Management Analysis of Foot-and-Mouth Disease Using Multi-dimensional Data Cube (다차원 데이터 큐브 모델을 이용한 구제역의 위기 대응 방안 분석)

  • Noh, Byeongjoon;Lee, Jonguk;Park, Daihee;Chung, Yongwha
    • The Journal of the Korea Contents Association
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    • v.17 no.5
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    • pp.565-573
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    • 2017
  • The ex-post evaluation of governmental crisis management is an important issues since it is necessary to prepare for the future disasters and becomes the cornerstone of our success as well. In this paper, we propose a data cube model with data mining techniques for the analysis of governmental crisis management strategies and ripple effects of foot-and-mouth(FMD) disease using the online news articles. Based on the construction of the data cube model, a multidimensional FMD analysis is performed using on line analytical processing operations (OLAP) to assess the temporal perspectives of the spread of the disease with varying levels of abstraction. Furthermore, the proposed analysis model provides useful information that generates the causal relationship between crisis response actions and its social ripple effects of FMD outbreaks by applying association rule mining. We confirmed the feasibility and applicability of the proposed FMD analysis model by implementing and applying an analysis system to FMD outbreaks from July 2010 to December 2011 in South Korea.

Foot-and-mouth disease: overview of motives of disease spread and efficacy of available vaccines

  • Saeed, Ali;Kanwal, Sehrish;Arshad, Memoona;Ali, Muhammad;Shaikh, Rehan Sadiq;Abubakar, Muhammad
    • Journal of Animal Science and Technology
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    • v.57 no.4
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    • pp.10.1-10.7
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    • 2015
  • Control and prevention of foot and mouth disease (FMD) by vaccination remains unsatisfactory in endemic countries. Indeed, consistent and new FMD epidemics in previously disease-free countries have precipitated the need for a worldwide control strategy. Outbreaks in vaccinated animals require that a new and safe vaccine be developed against foot and mouth virus (FMDV). FMDV can be eradicated worldwide based on previous scientific information about its spread using existing and modern control strategies.

Serological survey for Getah virus in domestic pigs of South Korea

  • Yu-Ri Park;Eun-Ju Kim;Hye Jeong Lee;Bang-Hun Hyun;Dong-Kun Yang
    • Korean Journal of Veterinary Research
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    • v.63 no.1
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    • pp.1.1-1.4
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    • 2023
  • Several outbreaks of Getah virus (GETV) have been reported in horses and pigs, causing large economic losses. However, there have been no reports describing serological survey for GETV in South Korea pigs. The present study conducted serological survey of GETV in South Korean pigs. A total of 670 whole blood samples were collected from domestic pigs. The overall seropositive rate was 26.4%, higher than the rates observed in racehorses in 2013-2014. Preparations for epidemics of novel diseases caused by climate change should include regular serological survey for these diseases, including GETV, and the development of vaccines against novel pathogens.

Isolation and identification of infectious bursal disease virus from broiler and layer chickens during the outbreak year 2007 in Bangladesh

  • Islam, Md. Taohidul;Mohiuddin, Mohammad;Hossain, Muhammad Tofazzal;Rahman, Md. Bahanur;Rahman, Md. Mostafizur;Rahman, Md. Siddiqur;Song, Hee-Jong;Islam, Md. Alimul
    • Korean Journal of Veterinary Service
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    • v.35 no.1
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    • pp.9-17
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    • 2012
  • The objective of the present study was to isolate and identify infectious bursal disease viruses (IBDVs) from broiler and layer chickens of outbreaks of infectious bursal disease (IBD) in three districts of Bangladesh. A total of 70 bursal samples were collected from dead broiler (n=40) and layer (n=30) chickens showing specific lesions of IBD from seven commercial poultry farms of three different districts (Mymensingh, Chittagong and Tangail) of Bangladesh during the year 2007. Five representative bursal samples from each farm were used for the isolation of IBDVs using 9-day-old embryonated eggs of seronegative flock of layer birds and for identification the samples were subjected to agar gel immunodiffusion test (AGIDT), immunohistochemistry (IHC) and reverse transcription-polymerase chain reaction (RT-PCR). Out of 35 bursal samples, IBDVs were successfully isolated from 28 (80%) samples. By AGIDT, 32 (91.4%) samples were found positive for IBDV antigen. Results of AGIDT clearly indicated that IBDVs detected in 29 bursal samples of six affected farms were identical to each other but not to IBDVs present in the remaining three samples of another farm. Indirect immunoperoxidase staining of the bursal sections revealed the presence of IBDV antigen in 32 (91.4%) samples and the IBDV antigen was detected mainly in the cortex of the lymphoid follicles of the bursal tissues. In histopathology, cell depletion, atrophy and necrosis were observed in many bursal follicles with severe edema of interfollicular septa. Of the 35 bursal samples, 34 (97.1%) samples generated 254 bp product by RT-PCR. In conclusion, the results of virus isolation and identification by AGIDT, IHC and the analysis of viral genome by RT-PCR confirmed the outbreaks of acute IBD in commercial poultry of Bangladesh. Moreover, histopathological findings and results of AGIDT gave a clear indication that the isolates from six outbreaks were different from classical strain and it seems to be of very virulent strain. On the other hand, the isolates from the other outbreak were similar to the classical strain.

ACUTE INFECTIOUS BURSAL DISEASE IN CHICKENS : PATHOLOGICAL OBSERVATION AND VIRUS ISOLATION

  • Chowdhury, E.H.;Islam, M.R.;Das, P.M.;Dewan, M.L.;Khan, M.S.R.
    • Asian-Australasian Journal of Animal Sciences
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    • v.9 no.4
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    • pp.465-469
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    • 1996
  • Pathological and virological investigations were conducted on suspected outbreaks of infectious bursal disease (IBD) in a broiler farm and five pullet-raising poultry farms of Mymensingh and Tangail districts of Bangladesh. About 80 to 100 percent chicks were affected at the age of 26 to 45 days and mortality varied from 20 to 30 percent in broilers and 40 to 80 percent in layer chicks. Signs, symptoms, gross and microscopic lesions were typical of acute IBD. Several isolates of virus could be obtained by embryo inoculation and the virus was diagnosed as infectious bursal disease virus (IBDV) by agar gel immunodiffusion test (AGID). The virus isolate belonged to the very virulent pathotype of IBDV causing 100 percent mortality in three weeks old chicks on experimental infection.

Outbreak of Rust Caused by Coleosporium asterum on Solidago virgaurea var. gigantea in Ulleung-do

  • Back, Chang-Gi;Nam, Gu-Youn;Lee, Seung-Yeol;Jung, Hee-Young
    • Mycobiology
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    • v.42 no.1
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    • pp.79-81
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    • 2014
  • From June to October 2012, severe outbreaks of rust disease on Solidago virgaurea var. gigantea were observed in 5 different regions of Ulleung-do, Korea. Typical rust symptoms appeared as yellow spots, uredinia on leaves, and massive urediniospores covering the entire plant. Severely infected plants became discolored and died. On the basis of its morphological and molecular characteristics, the causal agent was identified as Coleosporium asterum. This pathogen has been reported as rust disease on S. virgaurea in the Canada and United States. In Korea, rust disease on S. virgaurea var. gigantea was reported as Uromyces rudbeckia in 1992. To the best of our knowledge, C. asterum is a novel rust pathogen on S. virgaurea var. gigantea in Korea.

A Study on Outbreaks and Changes of Samyang-Sameum(三陽三陰) Disease of Sanghallon(傷寒論) (상한론(傷寒論) 삼양삼음병(三陽三陰病)의 발생(發生)과 변화(變化)에 대한 고찰)

  • Jang, Woo-Chang
    • Journal of Korean Medical classics
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    • v.19 no.4
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    • pp.169-181
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    • 2006
  • The Samyang-Sameum(三陽三陰) is the movement form peculiar to the cosmic dual forces. Since Byunggi(病氣) along with the Gyungkki(經氣), The Samyang-Sameum(三陽三陰) is the standard for a diagnosis of a disease's outbreak and change. Anyone of The Samyang-Sameum(三陽三陰) can cause a disease in a Gyungkki(經氣) because each and every human being has different Gyungkki(經氣). And, a disease may outbreak by anyone of Wind-Cold-Warmth-Heat(風寒溫熱). Guiding principles of the six Meridians(六經提綱) is set to diagnose which one of the Gyungkki(經氣) causes a disease. Sanghallon(傷寒論) shows several measures to diagnose the lapse of a disease at the beginning stage of external affection(外感) by Wind-Cold(風寒). It is most serious when the Jeongyung(傳經) symptom appears within 6 to 7 days after a disease outbreak since it indicates the exhaustion of true Eum(眞陰). It means the lapse of a disease that formation of dry stool(燥尸) by fast Jeonsok(轉屬) to Yangmyeong(陽明) after a Taeyang(太陽) is diseased. It also means that a position of disease is worsening by a sticking phase of disease when Yipeum(入陰) symptom after anyone of Samyang-Sameum(三陽三陰) is diseased.

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The Cultural Analysis of 2010-2011 Foot and Mouth Disease Massacre in Korea (2010-2011년도에 발생한 구제역 살처분 원인에 대한 문화 분석)

  • Kim, Seon-Kyung;Kim, Ji-Eun;Paek, Do-Myung
    • Journal of Environmental Health Sciences
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    • v.37 no.2
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    • pp.165-169
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    • 2011
  • Between January 2010 and March 2011, there were three outbreaks of foot and mouth disease (FMD) in South Korea. Over 3.45 million animals (5,660 farms) were slaughtered, which was 33.3% of the existing pigs, 8.4% of dairy cows and 3.4% of cattle. FMD disaster costs were estimated at around three billion Korean won. Nine civil servants were killed, over 150 people were wounded and 4,788 landfills were confronted with a pollution problem. Vaccination and slaughter are the two basic alternatives for eradication of FMD. Altho ugh slaughter is more violent, risky and expensive than vaccination, the Korean government had chosen only slaughter eradication by the end of 2010. Even though over three million animals were killed, FMD spread out over most of the country. Finally, the government chose to begin vaccination. Following vaccination, outbreaks decreased dramatically. The purpose of this report is a cultural analysis of the related decision-making process, laws and systems. For the culture analysis, we utilize interviews, symposiums, laws, FMD manual, government reports and press releases. In conclusion, we found that the FMD massacre was influenced by cultural and organizational factors. The cultural factors were economism, cheapening of the value of life, biased perceptions and fears. The organizational factors were a closed process of decision-making, monopoly system, a small homogeneous group and group-think. Therefore, more studies will be needed for those factors of FMD disasters in national-scale cases.