• 보건교육건강증진학회지
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• 제26권4호
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• pp.129-143
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• 2009

Objectives: The purpose of this study is to identify prevalence and related factors of the elderly, who took health examination, with metabolic syndrome. Methods: The health examination and lifestyle survey were performed for 21,512 adults at 60 years of age or older who took health examination in H health promotion center during January-March 2009. Results: The prevalence of metabolic syndrome for the subject was 24.0%. Of the subject with metabolic syndrome, the prevalence of the diseases was obesity 60%, abdominal obesity 78.5%, hypertension 82.6%, dyslipidemia 89.7% and diabetes 51.9%. In comparison of the relationship between metabolic syndrome and other diseases, the male subject with metabolic syndrome were significantly higher in BMI, waist circumference, systolic/diastolic blood pressure, hemoglobin, AST, ALT, $\gamma$-GTP, TG, AC glucose, creatinine than normal male(p<0.001). In comparison of the relationship between metabolic syndrome and lifestyle, more drinking frequency and amount in male and more drinking frequency in female were associated with increased risk of metabolic syndrome(p<0.01). Regardless of exercise intensity, practice of exercise contributed to reduce the risk of metabolic syndrome(p<0.01). Conclusion: In conclusion, TLC program, focused on lifestyle behaviors which is strongly associated with the prevalence of metabolic syndrome, should be developed for the improvement of life quality in the elderly with metabolic syndrome.

• Journal of Magnetics
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• 제15권4호
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• pp.209-212
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• 2010

Photoplethysmogram (PPG) and pressure pulse waveform (PPW) were compared and evaluated for the efficacy of stimulating knuckles by using the pulsed magnetic field. Both signals were observed simultaneously while the knuckles were exposed for 10 min to the pulsed magnetic field, with maximum field intensity of 0.8 T and transition time of 0.126 msec. After 5 min stimulation of the knuckles, the results showed that the aging indexes calculated from the second derivative of the PPG were increased from -1.913 to 0.072, and that of the PPW from -0.063 to 0.387. However, for the relatively long-term stimulation for 10 min, we found that the values of both the aging indexes of the second derivatives and augmentation index of the PPW returned to the starting level. The changes observed in characteristic factors such as the aging indexes of the second derivatives and augmentation index of the PPW indicate the potential of pulsed magnetic field stimulation as a therapeutic method for the treatment of patients with peripheral vascular disease.

• 치위생과학회지
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• 제12권5호
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• pp.486-492
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• 2012

치아 발생 동안 법랑질모세포에서의 Dynamin II 단백질 발현 강도는 출생 후 1일째 생쥐에 비해 출생 후 3일째와 출생 후 5일째 생쥐에서 각각 48%와 50%로 유의성 있게 증가하였으나, 출생 후 7일째와 출생 후 10일째 생쥐에서는 출생후 1일째의 생쥐에 비해 각각 16%와 12%로 유의성 있게 감소하였다. 이 결과로부터 Dynamin II가 분비법랑질모세포에서 형성되는 법랑기질 단백질인 amelogenin, ameloblastin, enamelin과 MMP-20 등과의 분비과립 수송에 연관됨이 보여졌다. Dynamin II는 치아 발생과정 중 발현되는 다양한 법랑기질을 구성하는 단백질을 포함하는 분비소포 형성을 촉진함으로써 과립의 수송에 관여할 것이라 생각되며 법랑질모세포에서의 법랑기질 단백질의 분비조절 가능성이 있음이 보여졌다. 따라서 Dynamin II를 통한 치주질환을 위한 유전자 치료와 법랑질 혹은 상아질의 유실 부분의 재생산의 자극과 촉진에도 임상적으로 사용될 수 있는 가능성이 있음이 보여졌다.

• 대한골관절종양학회지
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• 제4권1호
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• pp.30-36
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• 1998

Squamous cell carcinoma is a neglected disease entity in orthopedic oncology. The purpose of this study was to analyze overall survival and the role of surgery on survival and to evaluate the significance of possible prognostic factors. From Oct, 1986 to Aug, 1996, 57 patients were enlisted and 42 patients ere eligible. Inclusion criteria included more than one year follow-up and no distant metastasis at the first visit. Staging and survival followed AJC classification and Kaplan-Meier plot. Stage II included 17 cases and stage III, 25 cases. Thirty-eight patients underwent operations, chemotherapy, and/or radiotherapy, and the remaining four had operations only. The chemotherapeutic regimen was adriamycin-cisplatin. The average follow-up period was 45 months. The ten-year actuarial survival rate of whole patients was 65.4%. Location of primary lesion, stage, pathologic grading, and intensity of chemotherapy in the same stage showed a significant difference in survival. Nine out of 42 patients had local recurrence. Seven patients had inadequate wide margins and two had intralesional margins. Average period of recurrence from operation was 13(4-35)months. The operation itself had no impact on survival but a surgical margin of no less than 3cm from the lesion was important for local control. Pathological grade and staging were significant variables for long term survival. Acral lesion had a significantly higher chance of regional and distant metastasis but actual survival showed no difference. In stage II, aggressive chemotherapy could delay or reduce the chance of regional or distant metastasis.

• 정신신체의학
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• 제3권2호
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• pp.126-138
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• 1995

For investigating a disease specific psychological mechanism in various dermatological disorders, we tried to explore the difference in correlation among stress perception, locus of control as a coping strategy, depressive symptoms and pruritic symptoms in the patients with psychological pruritis and chronic urticaria. The subjects were composed of 32 patients with psychol-ogical pruritis and 67 patients with chronic urticaria(subject group), and 25 patients with organic pruritis and 59 patient with major depression(control group). Global assesment of recent stress scale(GARS), I-E locus of control scale, Beck Depression Inventory(BDI) and medical college of wisconsin center pain follow up questionnaire were used for assesement. The results were as follows: 1) There were a significant positive correlation between stress perception and depressive symptom in patients with psychological pruritis, chronic urticaria, and major depression but not hi organic pruritis. 2) In relationship between locus of control and depressive symptom, patients with psychological pruritis, organic pruritis, and major depression except chronic ruticaria showed a significant negative correlation. 3) For intensity and pattern of pruritis, there were positive relations with depressive symptom and stress perception only in patients with chronic urticaria. Above results indicate that stress perception and locus of contorl may play a significant role in the formation of psychological and dermatological symptoms in psychological pruitis and chronic urticaria. But the mechanisms of these processes are different in either disorder.

• 정보처리학회논문지B
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• 제13B권2호
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• pp.97-104
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• 2006

의사 표현 능력이 떨어지는 소아들은 질병 발생시 이를 효과적으로 자신의 불편함을 표현할 방법이 없다. 따라서 임상의들은 소아 환자의 부모들로부터 문진(inquiring)을 통해 질병 진단을 하고 있는 것이 현 실정이며 이는 잘못된 진단 결과를 초래 할 수 있는 문제점을 가지고 있다. 이를 위해 본 연구에서는 인체 오장 육부의 생체 신호가 안면과 음성에 반영되어 나타난다는 한방 원리를 이용하여 소아 망진, 소아 청진 기기를 개발한다. 그 결과 진단시 임상의들의 직관을 시각화, 객관화, 정량화하여 소아 질병 진단의 정확성을 기하고자 한다. 본 논문은 전체 개발 시스템 중 그 첫 번째 작업 수행 결과로서 소아 망진의 경우 색상 보정, YCbCr 적용과 살색 영역 선정 그리고 오관 및 명당 추출 방법 등을 개발한다. 또한 소아 청진의 경우 피치, 강도, 포먼트 분석을 통해 영아 산통 질병의 울음소리 특성을 수치화하였으며 이를 통해 임상의들의 직관을 객관화한다. 끝으로 실험에 의해 제안한 방법의 유용성을 입증한다.

• 동의생리병리학회지
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• 제20권1호
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• pp.235-244
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• 2006

There is much confusion in the field of Rhinitis regarding how to best measure disease severity objectively, Therefore, we aimed to establish a new adequate scoring system for Rhinitis, that should be based on comparison analysis of various scoring systems. We report as follows. We researched for data relating to severity scoring systems for rhinitis in Entrez PubMed from 1995 to 2005 and in Kiss Kstudy. Results and Conclusions: Properties of severity scoring systems were validity, sensitivity of change and ease of use. The essential items of severity scoring systems were subjective symptoms. The criterion of severity were divided into subjective symptoms and complication and Quality of Life. Intensity items are nasal obstruction, rhinorrhea, sneezing, itching, Postnasal drip, nasal mucosa swelling, nasal mucosa color, complication. Subjective symptoms is difficulty of Life. The significant items of severity scoring system are nasal symptoms. The whole score does with the maximum 30 scores. As it were, we assumed nasal symptoms accounted for around 80% of each total score, with complication and difficulty of Life representing 20%.

• The Korean Journal of Pain
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• 제34권4호
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• pp.471-478
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• 2021

Background: The effect of lumbar spinal stenosis (LSS) and peripheral vascular disease (PVD), which occurs with similar degenerative conditions, when seen together, has not been studied. The aim of this study is to examine and compare the relationship between pain, balance, disability, fear of falling, and kinesiophobia in LSS patients with intermittent vascular claudication (IVC). Methods: Seventy-two patients diagnosed with LSS using magnetic resonance imaging participated in this study. Thirty-five patients with IVC symptoms and showing vascular lesions by lower extremity venous and arterial Doppler ultrasonography imaging were included in the IVC-LSS group. The pain, static balance, dynamic balance, disability, fear of falling, and kinesiophobia were evaluated using the numeric rating scale, single leg stance test, Time Up and Go (TUG), the Oswestry Disability Index (ODI), Fall Efficacy Scale-International (FES-I), and Tampa Scale for Kinesiophobia (TSK), respectively. Results: Age and female sex were found to be higher in the IVC-LSS group (P = 0.024; P = 0.012). The IVC-LSS group had a shorter single leg stance time and TUG test duration, pain intensity, ODI, FES-I, and TSK scores were higher than patients with LSS (P = 0.001). Pain, fear of falling, and kinesiophobia were moderately correlated with disability in the IVC-LSS group. No relationship was found between pain and dynamic balance. Also, the pain was not related to kinesiophobia. Conclusions: The findings indicated that IVC causes loss of balance and an increase in pain, disability, fear of falling, and kinesophobia in patients with LSS.

• Parasites, Hosts and Diseases
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• 제56권6호
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• pp.625-632
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• 2018

Malaria remains one of the leading health burdens in the developing world, especially in several sub-Saharan Africa countries; and Uganda has some of the highest recorded measures of malaria transmission intensity in the world. It is evident that the prevalence of malaria infection, the incidence of disease, and mortality from severe malaria remain very high in Uganda. Although the recent stable political and economic situation in the last few decades in Uganda supported for a fairly good appreciation of malaria control, the declines in infection, morbidity, and mortality are not sufficient to interrupt transmission and this country is among the top 4 countries with cases of malaria, especially among children under 5 years of age. In fact, Uganda, which is endemic in over 95% of the country, is a representative of challenges facing malaria control in Africa. In this study, we evaluated an active case detection program in 6 randomly selected villages, Uganda. This program covered a potential target population of 5,017 individuals. Our team screened 12,257 samples of malaria by active case detection, every 4 months, from February 2015 to January 2017 in the 6 villages (a total of 6 times). This study assessed the perceptions and practices on malaria control in Kiyuni Parish of Kyankwanzi district, Uganda. Our study presents that the incidence of malaria is sustained high despite efforts to scale-up and improve the use of LLINs and access to ACDs, based on the average incidence confirmed by RDTs.

• 한국콘텐츠학회논문지
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• 제19권7호
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• pp.166-175
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• 2019

전통의학의 체질론은 현대의학과는 구분되는 특성으로, 사상의학은 건강유지의 관점을 폐비간신(肺脾肝腎)의 기능적 강약(强弱)으로 구분하여 인체 장부(臟腑)의 체질에 따른 기능적 균형이 어떠한 조건에서 불균형이 되는 상태를 병의 주요한 요인으로 파악하였다. 아유르베다는 우리 몸에 존재하는 3개 "도샤(Dosha)'의 균형을 건강 유지의 기본으로 생각하고 질병이 생기는 이유를 체내 에너지 조절 기능을 하는 바따(Vata), 신진대사와 소화 기능을 담당하는 삣타(Pitha), 체온조절 기능을 담당하는 카파(Kapha)의 균형이 깨어졌기 때문으로 보았고 세가지 도샤(tridosha)가 균형을 맞추면 스스로 치유된다고 하였다. 체질에 따른 질병의 특징과 경향을 알아 치료에 접근하고 일상생활의 건강관리까지 포함하고 있는 두 이론은 각 개인의 특성과 독립적이고 자율적인 생활습관이 중시되는 현대사회에서 일상 생활 건강 유지 및 예방을 위해 다양한 예방 치료법의 융합영역으로 해석될 수 있다고 생각된다. 본 연구에서는 사상 의학과 아유르베다 이론을 체질 관점에서 비교 분석하여 환자의 치유력과 회복력에 도움이 되고, 환자의 만족도 증가를 위한 체질 기반 개념을 이해하고 예방 의료분야에 있어서의 활용의 다양성에 대해 도움이 되고자 한다.