• International Journal of Computer Science & Network Security
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• 제22권7호
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• pp.1-12
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• 2022

The current progression in the Internet of Things (IoT) and Machine Learning (ML) based technologies converted the traditional healthcare system into a smart healthcare system. The incorporation of IoT and ML has changed the way of treating patients and offers lots of opportunities in the healthcare domain. In this view, this research article presents a new IoT and ML-based disease diagnosis model for the diagnosis of different diseases. In the proposed model, vital signs are collected via IoT-based smart medical devices, and the analysis is done by using different data mining techniques for detecting the possibility of risk in people's health status. Recommendations are made based on the results generated by different data mining techniques, for high-risk patients, an emergency alert will be generated to healthcare service providers and family members. Implementation of this model is done on Anaconda Jupyter notebook by using different Python libraries in it. The result states that among all data mining techniques, SVM achieved the highest accuracy of 0.897 on the same dataset for classification of Parkinson's disease.

• Childhood Kidney Diseases
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• 제27권2호
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• pp.70-75
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• 2023

Dent disease is a rare inherited kidney tubulopathy caused by mutations in either the CLCN5 (Dent disease 1) or OCRL1 (Dent disease 2) genes, and which is often underdiagnosed in practice. A diagnosis is clinically suspected in patients with low-molecular-weight proteinuria, hypercalciuria, and one of the following: hematuria, nephrolithiasis, nephrocalcinosis, hypophosphatemia, or chronic kidney disease. Inheritance is X-linked recessive, meaning, these symptoms are generally only found in males; female carriers may have mild phenotypes. Genetic testing is only a method to confirm the diagnosis, approximately 25% to 35% of patients have neither the CLCN5 nor OCRL1 pathogenic variants (Dent disease 3), making diagnosis more challenging. The genotype-phenotype correlations are not evident with the limited clinical data available. As with many other genetic diseases, the management of patients with Dent disease concentrates on symptom relief rather than any causative process. The current treatments are mainly supportive to reduce hypercalciuria and prevent nephrolithiasis. Chronic kidney disease progresses to end-stage between the ages of the third to fifth decades in 30% to 80% of affected males. In this review, we aimed to summarize the literature on Dent disease and reveal the clinical characteristics and molecular basis of Korean patients with Dent disease.

• 한국데이터정보과학회:학술대회논문집
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• 한국데이터정보과학회 2001년도 추계학술대회
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• pp.76-78
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• 2001

Variable selection in oriental medical research is considered. Decision tree analysis algorithms such as CHAID, CART, C4.5 and QUEST have been successfully applied to a medical research. Paralysis disease is a highly dangerous and murderous disease which accompanied with a great deal of severe physical handicap. In this paper, we explore the use of CHAID algorithm for selecting variables for evidence-diagnosis of paralysis, disease. Empirical results comparing our proposed method to the method using Wilks $\lambda$ given.

• 대한한의학원전학회지
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• 제29권1호
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• pp.139-172
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• 2016

Objectives : The purpose of research thesis is an advanced interpretation of the Name of Constitutional Disease of Dong-uisusebowon(東醫壽世保元) 1901 edition(辛丑本) evaluated to interpretation incompleted, and application of clinical diagnosis by rivised interpretation. Methods : A study on translation of sasangin(四象人)'s constitutional disease is researched the methods of documentary research on Dong-uisusebowon(東醫壽世保元) 1901 edition(辛丑本) and 1894 edition(甲午本). Results : Result of analysis of 4 meaning unit is as follows. Viscera or entrails means root or terminus of organ whom getting disease. Cold or heat based means being chilled or hot of triple energizer. Eexterior or interior means origin of disease of exterior or interior. Cold or heat means being chilled or hot of digestive system. Conclusions : In the clinical diagnosis using revised interpretaion, diagnosis of exterior or interior disease can be decided by symptoms of Taeyang syndrome(太陽病)'s fever and aversion to cold or not. Diagnosis of cold or heat disease can be decided by diarrhea or constipation.

• 한국통신학회논문지
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• 제35권2B호
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• pp.191-196
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• 2010

흡연, 당뇨, 비만 및 스트레스 등에 의한 심장 질환이 증가됨에 따라 이로 인한 사망률이 늘어나면서 심장 질환은 현대 사회에서 조기 진단의 필요성을 제시하고 있는 실정이다. 특히 심장 질환에 대한 사람들의 무지와 무관심 때문에 발병율이 급격히 증가하고 있다. 따라서 이와 같은 심장 질환에 대한 사회적 현상을 해결하기 위해 본 논문에서는 동의보감에서 제시하고 있는 심장 상태에 대한 진단 이론을 기반으로 심장 질환의 조기 진단에 필요한 객관적 출력 변수를 설계하였다. 특히 심장 질환에 따른 발음의 부정확성을 입증하기 위해 성대의 진동 변화율을 추출하여 실험 집단간의 비교, 분석을 수행하였다. 이를 위해 본 논문에서는 표준어를 구사하는 성인 남성 중에서 심장 질환을 앓고 있는 환자들과 심장에 이상이 없는 정상인들로 피실험자 집단을 구성하고 이들의 음성을 수집하여 성대 진동의 변화율에 대한 비교, 분석을 통해 심장 질환에 대한 조기 진단 방법을 제안하였다.

• Nuclear Medicine and Molecular Imaging
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• 제41권2호
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• pp.102-111
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• 2007

Dementia is a major burden for many countries including South Korea, where life expectancy is continuously growing and the proportion of aged people is rapidly growing. Neurodegenerative disorders, such as, Alzheimer disease, dementia with Lewy bodies, frontotemporal dementia, Parkinson disease, progressive supranuclear palsy, corticobasal degeneration, Huntington disease, can cause dementia, and cerebrovascular disease also can cause dementia. Depression or hypothyroidism also can cause cognitive deficits, but they are reversible by management of underlying cause unlike the forementioned dementias. Therefore these are called pseudodementia. We are entering an era of dementia care that will be based upon the identification of potentially modifiable risk factors and early disease markers, and the application of new drugs postpone progression of dementias or target specific proteins that cause dementia. Efficient pharmacologic treatment of dementia needs not only to distinguish underlying causes of dementia but also to be installed as soon as possible. Therefore, differential diagnosis and early diagnosis of dementia are utmost importance. F-18 FDG PET is useful for clarifying dementing diseases and is also useful for early detection of the diseases. Purpose of this article is to review the current value of FDG PET for dementing diseases including differential diagnosis of dementia and prediction of evolving dementia.

• 사상체질의학회지
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• 제26권1호
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• pp.11-26
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• 2014

Objectives This research was proposed to present Clinical Practice Guideline(CPG) for Soeumin Disease of Sasang Constitutional Medicine(SCM): Diagnosis and Algorithm. This CPG was developed by the national-wide experts committee consisting of SCM professors. Methods We searched the literature and articles related to Soeumin Symptomatology diagnosis and algorithm. For developin diagnosis and algorithm, we searched the classification, ordinary symptom, present symptom of the Soeumin Symptomatology Results & Conclusions We classified the Soeumin Symptomatology by 4 steps: Exterior-Interior disease, favorable-unfavorable pattern, mild-moderate-severe-critical pattern, initial-intermediate-advanced pattern. And at the unfavorable pattern, ordinary symptom is very important. So Doctors focuss on the symptom of unfavorable's ordinary symptom such as temperament inclined symptom, excessive sweating, diarrhea, and vexation.

• 대한후두음성언어의학회지
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• 제18권2호
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• pp.102-107
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• 2007

Laryngopharyngeal reflux disease (LPRD) is the result of retrograde flow of gastric contents to the laryngopharynx. Laryngoscopic findings and special questionnaires are first step of diagnosis of LPRD. Empiric trials of Proton pump inhibitor' test (PPI test) is recommended as treatment and diagnosis. However confirmation of reflux is then recommended primarily in patients with persistent symptoms despite acid-suppressive therapy. The 24 hour ambulatory double pH monitoring has been a gold standard method in diagnosis of LPRD even though it has some limitation. The combined multichannel intraluminal impedance and pH monitoring is a new-rising test tool. It can detect acid/non-acid, liquid/gaseous reflux and clearance of refluxate. The water siphon test is also used for diagnosis of LPRD.

• 대한유전성대사질환학회지
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• 제5권1호
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• pp.108-115
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• 2005

Inherited metabolic diseases (IMD) comprise a large class of genetic diseases involving disorders of metabolism. The majorities are due to defects of single genes that code for enzymes that facilitate conversion of various substances into others. Because of the multiplicity of conditions, many different diagnostic tests are used for screening of IMD. Molecular genetic diagnosis is the detection of pathogenic mutations in DNA and/or RNA samples and is becoming a much more common practice in medicine today. The purpose of molecular genetic testing in IMD includes diagnostic testing, pre-symptomatic testing, carrier screening, prenatal diagnosis, preimplantation testing, and population screening. However, because of the complexity, difficulty in interpreting the result, and the ethical considerations, an understanding of technical, conceptual, and practical aspects of molecular genetic diagnosis is mandatory.

• 사상체질의학회지
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• 제27권1호
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• pp.110-124
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• 2015

Objectives This study was purposed to develop the clinical practice guideline for examination of Sasangin disease and diagnosis for Sasang Constitution. Methods "Donguisusebowon" and many articles were reviewed and examined for developing clinical practice guidelines. And "Guideline for Educating Public Health Korean Medical Doctors on Diagnosis of Sasang Constitution" was basically used to develop clinical guidelines. Results & Conclusions By researching and discussing the examination of Sasangin disease and diagnosis for Sasang Constitution, we make the principle of the clinical practice guideline, including methods using body shape, facial shape, vocal characteristic and personality etc.