• 대한의생명과학회지
• /
• 제15권2호
• /
• pp.135-139
• /
• 2009

The CA(carbohydrate antigen)19-9 is complex protein that can be used as an important marker which aids the clinical diagnosis and prognosis of various pancreaticobiliary tumors. However, it was also reported that there were some CA19-9 positive patients with benign disease as using RIA method. The purpose of this study is to evaluate the clinical usefulness of serum level of CA19-9 with RIA(radioimmuno assay), CIA(chemiluminescence immuno assay), and conventional liver function tests. The correlation between CIA and RIA in CA19-9 of pancreatobiliary disease was 0.9833(P<0.01). Also, the correlations between CIA and RIA in CA19-9 of benign and malignant pancreaticobiliary tumor patients was 0.8714(P<0.01) and 0.9727(P<0.01) respectively. The correlation between CA19-9 and ALP was 0.5140(P<0.01) and CEA was 0.3385(P<0.05) as using CIA. The measurement of serum CA19-9 levels by CIA method may be useful in differentiating patients with malignant disease from those with benign disease in pancreaticobiliary tumors.

• The Journal of Korean Physical Therapy
• /
• 제29권2호
• /
• pp.62-68
• /
• 2017

Purpose: This study was conducted to identify the impacts of stroke patients' general and disease-related properties on depression and family support. Methods: Subjects consisted of 79 persons who were diagnosed with cerebral hemorrhage and cerebral infarction and met the criteria for selection. The Korean version of Beck depression inventory (BDI) and a revision of the family support developed by Cobb were used. Frequency analysis of the subjects' general and medical history properties was conducted, and one way ANOVA was utilized to evaluate the degree of depression and family support with respect to the properties. Pearson's correlation coefficient was conducted to investigate the degree of depression and family support. Results: Participants showed no significant difference in depression based on the subjects' general and disease-related properties (p>0.05), although there were significant differences in family support based on marital status, hobbies and the medical expenses payers (p<0.05). The correlation between family support and depression was r=-0.491 (p<0.01). Conclusion: Through the results of this study, it was found that general and disease-related properties would not have any impact on depression while they would affect family support.

• 대한기관식도과학회지
• /
• 제6권2호
• /
• pp.152-158
• /
• 2000

Backgroud and Objectives： Because the pain is subjective in human, we frequently need the objective tool for estimation of pain. The Visual Analog Scale (VAS) is a method for pain grading, but it is also a subjective method. The purpose of this study is to seek an objective method for measurement of pain. Author suggests that the estimation of local body temperature may be associated with the severity of pain in tonsillar disease and the change of it measured by Digital Infrared Thermographic Imaging (DITI), may also be correlated with the change of pain. Materials and Method : Four groups were selected and measured for VAS and body temperature in DITI. Group A and B were post-tonsillectomy groups divided by age. Group C was acute tonsillitis group. Group D was peritonsillar abscess group. Results : In Group A and B, the subjective VAS was significantly correlated with objective local body temperature (correlation coefficient r=0.673, 0.647) and significant correlation was also present in acute tonsillitis and peritonsillar abscess groups(r=0.596,0.642). Conclusion : The change of pain was strongly associated with that of local body temperature in tonsillar disease. DITI is a useful method for objective grading of pain and can be used for the study of postoperatve pain and effectiveness of pain control.

• 한국콘텐츠학회논문지
• /
• 제21권2호
• /
• pp.236-247
• /
• 2021

본 연구의 목적은 만성질환자의 건강 관련 의사결정에 대한 자율성 선호도에 영향을 미치는 요인을 확인하기 위함이다. 대상자는 일개 보건소에 등록된 만성질환자 522명이다. 수집된 자료는 SPSS Win 26.0 ver. 프로그램을 이용하여 기술통계, t-test, ANOVA, Scheffe-test, Pearson's correlation coefficients, multiple linear regression으로 분석하였다. 연구결과, 만성질환자의 일반적 의사결정 선호도의 영향요인은 건강에 대한 관심정도(β=-.17, p<.001)이었으며. 정보추구 선호도의 영향요인은 성별(β=-.20, p<.001)과 진료 시 질문하는 횟수(β=.09, p=.030)이었다. 본 연구는 만성질환자들이 본인의 치료 과정에서 주도적으로 역할을 할 수 있도록 환자의 특성을 고려해야 하며, 환자의 주도적이고 효율적인 의사결정을 돕기 위하여 의료인의 효과적인 의사소통 전략 수립이 필요함을 시사한다.

• Journal of Chest Surgery
• /
• 제25권6호
• /
• pp.650-660
• /
• 1992

To elucidate a potential contribution of endotheline-1[ET-1] to the genesis of pulmonary hypertension and postoperative pulmonary hypertensive crisis in the patients with heart disease, we measured plasma levels of the ET-1 during perioperative period of open heart surgery. In addition, we examined changes of ET-1 during perioperative period and correlations between ET-1 levels and hemodynamic variables. 12 patients including 5 acquired heart disease and 7 congenital heart disease patients were selected randomly as a study group, Group A and B, respectively. 6 patients proved not having heart or hemodynamic problem were selected as a control, Group C. 110 blood samples from pulmonary artery[ET-P] and radial artery[ET-S] were taken and assayed by Sep-pak extraction and RIA. ET-1 levels of Group A were ET-P, 3.94$\pm$5.31pg /ml, ET-S, 3.10$\pm$2.90pg/ml[p>0.05], Group B were ET-P, 1.63$\pm$0.62pg/ml, ET-S, 1.99$\pm$2.45pg/ml[p>0.05], Group C were ET-P, 1.97$\pm$2.02pg/ml, ET-S, 1.72$\pm$0.77pg/ml[p>0.05]. There were no statistically significant differences of ET-1 levels among the Group A, B, C[p>0.05]. There was no correlation between pulmonary artery pressure[PAP] and ET-1 level[p>0.05], and ET-1 levels were not increased even in the cases of pulmonary hypertensive criwis or low cardiac output syndrome, whereas significant correlation between ET-S and pulmonary vascular res-istance[Rp] [r=0.36, p<0.05], and negative correlation between ET-S and OS saturation of pulmonary artery[OS-P][r= -0.49, p<0.01] were identified. Another significant finding was peak increase of ET-1 levels in the postoperative period 1 hour[p<0.05] and then gra-dualy decrease through the postoperative period. In conclusion, ET-1 has no correlation with PAP, whereas correlation with Rp, and inverse correlation with OS-P. It is suggested that ET-1 is neither the direct causative substance of pulmonary hypertension nor pulmonary vasospasm but there must be increased production of ET-1 in chronic pulmonary hypertensive state. Counter-regulatory mechanism to ET-1 is speculated during the pulmonary vasospasm.

• The Journal of Korean Physical Therapy
• /
• 제26권2호
• /
• pp.48-55
• /
• 2014

Purpose: The purpose of this study was to examine correlations among UPDRS, respiratory function, and senior fitness and to investigate the effects of restrictive respiratory function on these factors in Parkinson's disease patients. Methods: Subjects (n=25, Hoehn & Yahr (H&Y) stage: 2-3, $69.3{\pm}5.9$ yrs) from D Hospital Parkinson's Disease Center at Busan metropolitan area in the Republic of Korea volunteered for this study. They performed the pulmonary function test, UPDRS, and the senior fitness test. SPSS 18.0 was used for analysis of data, and the collected data were analyzed using Pearson's correlation coefficient (n=25). In addition, Independent t-test was used for determination of differences between two groups (between the normal pulmonary function group (n=10) and the restrictive pulmonary function group (n=10)). Results: Forced vital capacity (FVC (L)) showed significant negative correlation (r=-0.44, p<0.05) with H&Y stage in Parkinson's disease patients, and chair stand showed significant negative correlations (r=0.41, 0.43, 0.42, p<0.05) with FVC (L), FVC (%), and FEV1 (L). FVC (%) showed significant positive correlations (r=0.44, r=0.44, p<0.05) with right and left back scratch. In addition, the restrictive respiratory function group showed significantly lower FVC (%) (p<0.01) and was significantly slower (p<0.05) in the 8-foot up-and-go test than the normal respiratory function group. Conclusion: In conclusion, these results suggest that restrictive respiratory function in PD was related to H&Y stage. In addition, agility of PD patients was lower in the restrictive respiratory function group than in the normal function group.

• 한국식품영양과학회지
• /
• 제24권1호
• /
• pp.24-29
• /
• 1995

Purpose of this study was to investigate correlation between blood pressure (systolic and diastolic) and dietary sodium, potassium intake pattern in the family members of normal cerebrovascular (CVA) disease, excluding patients themselves. Both mean values of systolic (125.8$\pm$23.7 vs 119.3$\pm$19.2mmHg) and diastolic(76.1$\pm$16.7 vs 71.6$\pm$12.5mmHg) bllood pressure in the family members of cerebrovascular disease patients were significantly higher than those of normal subjects. Systolic blood pressure was positively correlated with age, weibght, sodium in soybean paste, potassium in hotpepepr paste, soybean paste and meats in normal subjects group. In the family members of cerebrovascular patient, systolic blood pressure was possively correlated with age, weight, sodium in soy sauce, drinking water and potassium in soups. Interestingly, table salt intake was positively correlated with systosolic blood pressure in the family members of cerebrovascular disease patients. Diastolic bolld pressure was positively correlated with age, weight, table salt intake potassium in hotpepper paste and soybean paste in normal subjects group. Diastolic blood pressure was positively correlated with age, weight and table salt intake in the family members of cerebrovascular disease patients. Urinary potassium excretion was negatively correlated with both systolic and diastolic blood pressure in the family members of cerebrovascular disease patients.

• 성인간호학회지
• /
• 제27권4호
• /
• pp.375-383
• /
• 2015

Purpose: The purpose of this study was to identify the relationship of resiliency and symptom experience and depression. Subjects (N=152) were patients with chronic obstructive pulmonary disease (COPD).admitted to D University Medical Center in B City. Methods: Data collection was conducted from July 20 to August 25, 2013. The levels of symptom, resilience, and depression were measured using a seven question symptom experience measuring instrument, a 25-question resilience instrument, and a 15-question Short Geriatric Depression Scale (SGDS). The collected data were analyzed by descriptive analysis, Pearson's correlation coefficients, and path analysis using SPSS/Win 19.0 and AMOS 5.0. Results: There was a significant negative correlation between symptom and resilience, a significant positive correlation between symptom and depression, and a significant negative correlation between resilience and depression. Symptom showed a direct effect on depression and an indirect effect on depression scores through resilience as a mediating variable. Conclusion: It is necessary to develop nursing intervention programs to relieve symptom in COPD patients, and to develop appropriate resilience enhancement programs to reduce their depression.

• 대한한의학회지
• /
• 제28권1호통권69호
• /
• pp.249-259
• /
• 2007

Objectives : We performed this study to analyze correlation among hair tissue minaral ratio, autonomic function and obesity. Methods : Subjects were gathered from January 2005 to March 2007. This study was carried out on 263 subjects who had visited Garosero oriental clinic and had no previous cardiovascular disease and thyroid disease. Heart rate variability (HRV) parameters, tissue mineral ratio and obesity degree were statistically compared with correlation and T-test analysis. Results : The results of this study are summarized as follows : 1. Normal group were predominant over obesity group in HRV parameters(SDNN, RMSSD, VLF, LF, HF). 2. Ca/P, Ca/K, Na/K and Fe/Cu, Na/Mg ratio in hair tissue mineral ratio have correlation with BMR, BMI and waist circumference. 3. Ca/P ratio has correlation with LF norm in HRV, and Na/K with HF, Na/Mg with LF, equally. Conclusions : Taken together these results may suggest that there are significant relationships between hair tissue mineral analysis and HRV.

• 한국임상수의학회지
• /
• 제39권6호
• /
• pp.287-293
• /
• 2022

Radiographic left atrial dimension (RLAD) is a useful measurement to assess left atrial enlargement in dogs. There are studies on the use of RLAD on various breeds of dogs, but no study on a specific breed with myxomatous mitral valve disease (MMVD). This study was conducted to compare RLAD measurements in Maltese dogs with MMVD ACVIM stage B1 and B2, and also to investigate the correlation of RLAD with the LA:Ao ratio. A total of 29 Maltese dogs were the subjects of this study. Each dog was diagnosed with MMVD ACVIM stage B1 or B2 based on physical examination, thoracic radiography, and echocardiography. The vertebral heart size (VHS), RLAD, LVIDDn, and LA:Ao ratio were measured and compared to evaluate the differences. There were significant differences in the RLAD, LVIDDn, and LA:Ao ratio between dogs with MMVD ACVIM stage B1 and those with stage B2. There was a significant correlation between the LA:Ao ratio and both the RLAD and VHS measurements, but the correlation coefficient was higher for RLAD. The RLAD scores exhibited a significant difference between dogs with ACVIM Stage B1 and with those with B2, and these scores had a higher correlation with the LA:Ao ratio measured by echocardiography than with VHS.