• Title/Summary/Keyword: discriminant function analysis

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Development of the Self-Care Non-adherence Risk Assessment Scale for Patients with Chronic Illness (만성질환자의 자가간호 불이행 위험 사정도구 개발)

  • Jo, Mirae;Oh, Heeyoung
    • Research in Community and Public Health Nursing
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    • v.32 no.4
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    • pp.415-429
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    • 2021
  • Purpose: The purpose of this study was to develop the Self-Care Non-adherence Risk Assessment Scale (SCNRAS) for patients with chronic illness in South Korea. Methods: This study was conducted from April to July, 2020 and utilized a convenience sampling method to recruit 336 patients with chronic illness from three hospitals located in South Korea. The content, factorial structure, item-convergent/discriminant validity, convergent validity, internal consistency reliability, and test-retest reliability of the scale were evaluated. The data were analyzed using exploratory and confirmatory factor analyses, Pearson's correlation coefficient, Cronbach's α, and intra-class correlation coefficient. Results: The exploratory and confirmatory factor analyses yielded six-factors. Convergent validity was demonstrated using measures of defining issues. Internal consistency reliability and test-retest reliability were found to be acceptable, as indicated by a Cronbach's α of .65~.81 and an intra-class correlation coefficient of .93~.98. The Self-Care Non-adherence Risk Assessment Scale for patients with chronic illness is a new instrument that comprehensively measures the knowledge, skill, physical function status, access to health care, social support, motivation, and confidence. It comprises 18 items scored on a 5-point Likert scale. The validity and reliability of the scale were verified. Conclusion: The scale developed through this study is expected to screen those who need nursing intervention early by predicting the self-care non-adherence risk group.

Diabetes disrupts osteometric and trabecular morphometric parameters in the Zucker Diabetic Sprague-Dawley rat femur

  • Robert Ndou;Vaughan Perry;Gcwalisile Frances Dlamini
    • Anatomy and Cell Biology
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    • v.57 no.2
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    • pp.294-304
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    • 2024
  • Type 2 diabetes mellitus is increasingly becoming more prevalent worldwide together with hospital care costs from secondary complications such as bone fractures. Femoral fracture risk is higher in diabetes. Therefore, this study aimed to assess the osteometric and microarchitecture of the femur of Zucker Diabetic Sprague-Dawley (ZDSD) femur. Ten-week-old male rats (n=38) consisting of 16 control Sprague-Dawley (SD) and 22 ZDSD rats were used. The rats were terminated at 20 weeks and others at 28 weeks of age to assess age, diabetes duration effects and its severity. Bilateral femora were taken for osteometry, bone mass measurements and micro-focus X-ray computed tomography scanning to assess the trabecular number (TbN), thickness (TbTh), spaces (TbSp), bone tissue volume to total volume (BV/TV) and volume (BV). Diabetic rats had shorter (except for 20-weeks-old), lighter, narrower, and less robust bones than SD controls that wered more robust. Although cortical area was similar in all diabatic and control rats, medullary canal area was the largest in ZDSD rats. This means that the diabetic rats bones were short, light and hollow. Diabetic rats aged 20 weeks had reduced BV, BV/TV, TbN with more spacing (TbSp). In contrast, the 28 weeks old diabetic rats only showed reduced BV and TbN. Discriminant function analysis revealed, for the first time, that osteometric parameters and TbTh, TbN, and TbSp were affected by diabetes. This knowledge is valuable in the management of diabetic complications.

15-Year Long-Term Follow-Up on the Progression to Liver Cancer in a Patient with Alcoholic Hepatitis Who Continued Drinking: A Case Report and Clinical Approach (음주를 지속한 알코올성 간염 환자의 간암 진행에 대한 15년 장기 추적 관찰 : 증례 보고 및 임상적 접근)

  • Nahyun Cho;Hye-ri Bae;Nam-hun Lee
    • The Journal of Internal Korean Medicine
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    • v.45 no.4
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    • pp.823-837
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    • 2024
  • Objectives: This case report aims to present the long-term clinical progression of a patient diagnosed with alcoholic hepatitis, which subsequently advanced to liver cirrhosis and hepatocellular carcinoma over a 15-year period. The report highlights the impact of continued alcohol consumption on the progression of alcoholic liver disease and provides a clinical analysis of the course of the disease. Methods: A single patient diagnosed with alcoholic hepatitis was analyzed retrospectively. The patient was treated with both traditional Korean medicine and conventional medicine over multiple hospitalizations between 2012 and 2021. Clinical outcomes were monitored through blood chemistry, imaging studies, and Child-Pugh scores. Results: Despite consistent treatment, the patient's continued alcohol consumption accelerated the progression from alcoholic hepatitis to cirrhosis and, eventually, hepatocellular carcinoma. The patient's condition remained classified as Child-Pugh B throughout the follow-up, and he ultimately expired in 2023. Conclusion: This case emphasizes that alcohol cessation is crucial in preventing the rapid progression from alcoholic hepatitis to liver cancer. Early detection through noninvasive fibrosis tests such as FibroScan, proactive management of complications, and the use of prognostic tools such as Maddrey Discriminant function (MDF), in addition to patient education, are essential for better outcomes.

Characteristics of Patients Who Need Hypnotics on the Night before Elective Surgery (수면전일 수면제를 필요로 하는 환자들의 특성)

  • Lee, Soo-In;Yoon, Jin-Sang;Lee, Hyung-Young
    • Sleep Medicine and Psychophysiology
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    • v.4 no.2
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    • pp.172-180
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    • 1997
  • Objects : This study was carried out to investigate characteristics of patients who need hypnotics on the night before elective surgery as well as contributing variables for the necessity of hypnotics. Methods : After reviewing the clinical charts of patients who were scheduled to receive surgery by general anesthesia the following day, researchers had semi structural interviews with patients. In addition, Spielberger's State-Trait Anxiety Inventory(SSTAI), Beck Depression Inventory(BDI), Zung's Self-Rating Pain and Distress Scale(ZPDS), and Presleep and Postsleep Questionnaires were administered to patients. A total of 167 patients, who gave reliable information, were divided into two groups based on subjective judgement regarding the necessity for hypnotics on the night before surgery; 29 eligibles for hypnotics and 138 non-eligibles for hypnotics. Demographic and clinical characteristics of patients, some possible factors affecting sleep, psychological characteristics of patients and daytime status and nighttime sleep before surgery were compared between the two groups. In addition, discriminant function analysis was done to find the variables which would best discriminate among patients who differ in terms of necessity for hypnotics on the night before surgery. Results : There was no difference in demographic and clinical characteristics between the two groups; however, the satisfaction level with ward environment was significantly lower in the eligible group for hypnotics than the non-eligible group. Psychologically, the eligible group for hypnotics, compared to the non-eligible group, showed significantly more severe depression, pain, and distress; whereas anxiety level was not different between the two groups. For nighttime sleep before surgery, the eligible group for hypnotics, compared to the non-eligible group, expected poorer sleep before retiring and in fact, reported poorer sleep the following morning. In discriminant function analysis, 'expectation for sleep' and 'pain and distress' were the most potent contributors to discriminate the necessity of hypnotics. Conclusion : For the improvement of the patient's sleep on the night before elective surgery, giving hypnotics and/or analgesics should be determined by patient's opinion about the necessity of the drugs rather than by the therapist's own judgement or any other objective indices.

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Fragrance Analysis Using GC-MS and Electronic Nose in Phalaenopsis (GC-MS와 전자코를 이용한 팔레놉시스 향기 분석)

  • Park, PueHee;Yae, ByeongWoo;Kim, MiSeon;Lee, YoungRan;Park, PilMan;Lee, DongSoo
    • FLOWER RESEARCH JOURNAL
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    • v.19 no.4
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    • pp.219-224
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    • 2011
  • Phalaenopsis (P.) has various species, and some of them have strong fragrance. There are fragrant species such as P. bellina, P. violacea, P. schilleriana and used in breeding program for fragrant Phalaenopsis. This study was performed for establishment of fragrance analysis system using GC-MS and electronic nose in eight P. resources. We analyzed fragrant compound using the tissue of sepal, petal, column, and lip of P. '3010'. The percentage of the major compound was high in the petal and lip tissues. The main compound emitted from P. bellina was linalool (21.21%). It was possible that fragrance pattern could be analyzed among the resources using the electronic nose. Discriminant function analysis (DFA) was more useful than the principal component analysis (PCA) in statistics program. We utilized GC-MS method for the major compounds of flower from our breeding materials. This study would be useful to the fragrant analysis system for the fragrant orchid breeding in the future.

Identification of New, Old and Mixed Brown Rice using Freshness and an Electronic Eye (신선도와 전자눈을 이용한 현미 신곡, 구곡 및 혼합곡의 판별)

  • Hong, Jee-Hwa;Park, Young-Jun;Kim, Hyun-Tae;Oh, Sang Kyun
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.63 no.2
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    • pp.98-105
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    • 2018
  • The sale of brown rice batches composed of rice produced in different years is prohibited in Korea. Thus, new methods for the identification of the year of production are critical for maintaining the distribution of high quality brown rice. Here, we describe the exploitation of an enzyme that can be used to discriminate between freshly harvested and one-year-old brown rice. The degree of enzyme activity was visualized through freshness test with Guaiacol, Oxydol, and p-phenylenediamine reagents. With electronic eye equipment, we selected 29 color codes for identifying new brown rice and old brown rice. The discrimination power of selected color codes showed a minimum of 0.263 to a maximum of 0.922 and an average value of 0.62. The accuracy with which new brown rice and old brown rice could be identified was 100% in principal component analysis (PCA) and discriminant function analysis (DFA). The DFA analysis had greater discriminatory power than did the PCA analysis. A verification test using new brown rice, old brown rice, or a mixture of the two was then performed to validate our method. The accuracy of identification of new and old brown rice was 100% in both cases, whereas mixed brown rice samples were correctly classified at a rate of 96.9%. Additionally, in order to test whether the discriminant constructed in winter can be applied to samples collected in summer, new and old brown rice stored for 8 months were collected and tested. Both new and old brown rice collected in summer were classified as old brown rice and showed 50% identification accuracy. We were able to attribute these observations to changes in enzyme content over time, and therefore we conclude, it will be necessary to develop discriminants that are specific to distinct storage periods in the near future.

The Chemistry and Origin of Amphibolitic Rocks in the Sobaegsan Metamorphic Belt and the Ogbang and Sangdong Tungsten Mine Areas, Korea (소백산변성대(小白山變成帶)와 옥방(玉房) 및 상동중석광상내(上東重石鑛床內)의 각섬석질암(角閃石質岩)의 지화학(地化學) 및 성인(成因)에 관(關)한 연구(硏究))

  • So, Chil-Sup;Kim, Sang-Myeong
    • Economic and Environmental Geology
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    • v.8 no.3
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    • pp.147-164
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    • 1975
  • 19 amphibolite samples from the Precambrian Sobaegsan metamorphic belt including the Ogbang mine amphibolites were analyzed for 24 elements each, by wet chemical and emission spectroscopic methods. All the chemical data were evaluated by the methods outlined by Evans and Leake(1960) and Leake(1964) and by Shaw and Kudo(1965). The chemical similarity of all the studied rocks analyzed to basic igneous rocks is consistently indicated particularly by trace element abundance and variation trends. Petrography and oxidation ratios were also considered in attempting to determine the nature of the parent rocks. 3 analyses of W-bearing mafic metamorphic rocks from Sangdong area of the Ogcheon geosynclinal zone are also presented and discussed. Geochemical data for these latter rocks have been possibly derived from mafic tuffs deposited in an area of carbonate deposition.

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Effect of Light Emitting Diode and Fluorescent Light on Volatile Profiles of Soybean Oil during Storage (콩기름 저장 중 휘발성분에 대한 LED와 형광등 광원 조사의 영향)

  • Park, In-Seon;Choi, Duck-Joo;Youn, Aye-Ree;Lee, Youn-Jung;Kim, Youn-Kyeong;Kim, Mun-Ho;Choi, So-Rye;Kim, Ki Hwa;Dong, Hyemin;Han, Hyun Jung;Noh, Bong Soo
    • Korean Journal of Food Science and Technology
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    • v.45 no.6
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    • pp.763-769
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    • 2013
  • Soybean oil was stored in polyethylene for 12 weeks at $20^{\circ}C$. The influence of LED (light emitting diode) irradiation on four different wavelengths and fluorescent light was investigated. The pattern changes of volatile components in soybean oil was analyzed by electronic nose based on mass spectrometer. The obtained data from electronic nose were analyzed by discrimination function analysis. Under fluorescent light, the discriminant function first score (DF1) was significantly moved from positive position to negative one after 4-12 weeks. It means that the volatile compounds related to quality of lipid. It was shown to increase slowly due to green light of LED treatment, while blue and white LED light was influenced significantly as well as fluorescent light irradiation. Selection of LED irradiation would provide to keep good quality of soybean oil under distribution chain system.

Analysis of volatile compounds from retort pouches during heating using an electronic nose (전자코를 이용한 가열 중 레토르트 파우치로부터 발생한 휘발성분의 분석)

  • Jung, Hyo Yeon;Park, Eun Young;Choi, Jin Young;Lee, Soo Jin;Noh, Bong Soo
    • Korean Journal of Food Science and Technology
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    • v.49 no.1
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    • pp.14-19
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    • 2017
  • The objective of this study was to analyze the volatile changes occurring in retort pouches during heating using a mass spectrometry-based electronic nose. The data obtained by the electronic nose analysis was used to generate a discriminant function analysis plot. The plot showed that volatile compounds of the heated water in the retort pouch were increased by the interaction between container and water as the heating time increased. Conversely, volatile compounds of the container itself decreased when only the container was measured separately. This result means that volatile compounds from the packaging material migrated into the water. In the case of heated beef bone soup, volatile compounds were increased compared to the unheated beef bone soup after 20 min of heating. According to the results of GC/MS, nonanal and 3,5-di-tert-butyl-4-hydroxytoluene (BHT) were detected in the heated water and nonanal, heptanal, octanal, and BHT were detected in the heated beef bone soup.

Pattern Recognition Analysis for Volatile Compounds of the Whole, Skim, UHT-, HTST-, and LTLT-Milk under LED Irradiations (여러 가지 LED를 처리한 전지유, 무지방 우유, LTLT, UHT, HTST 처리 우유의 휘발성분 패턴 분석)

  • Kim, Ki-Hwa;Hong, Eun-Jeung;Park, Sue-Jee;Kang, Jee-Won;Noh, Bong-Soo
    • Food Science of Animal Resources
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    • v.31 no.4
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    • pp.596-602
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    • 2011
  • The objective of this study was to analyze the pattern recognition of volatile compounds from different types of milk under LED (Light Emitting Dioxide) irradiation for 6 d. Yellow, red, blue, dark, and fluorescent light were produced using LED equipment. A mass spectrometry-based electronic nose and DFA (discriminant function analysis) were used to determine the change in volatiles from different types of milk under LED irradiation. As the LED exposure time was increased, DF1 of whole milk changed considerably under blue light, while that of skim milk changed significantly under red and yellow light irradiation. Among the types of milk tested, the most light-induced oxidation sample was LTLT milk under blue light. The volatile compounds that were shown to increase due to LED treatment in the electronic nose analysis, which was based on MS, were mainly acetaldehyde, propanal, pentanal, hexanal, heptanal, nonanal, 3-methyl butanal, 2-methyl propanal, 2-butanone, 2-pentanone, 2-hexanone, and 2-heptanaone and 2-nonanone.