• 물과 미래
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• 제21권3호
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• pp.291-291
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• 1988

2차원 흐름이 원주주위를 지날 때 발생하는 흐름의 변화가 기본방정식인 연속방정식과 운동량방정식에 의하여 수치적으로 해석된다. 수치해석 과정은 기본방정식에 유함수, 와도 및 흐름의 특성을 나타내는 무차원 매개변수를 도입하여 무차원 유함수-와소수송식을 유도한 후, successive over relaxation scheme과 alternating direct implicit scheme으로 수행된다. 수치실험은 레이놀즈수 125-275를 기존의 수치해석에서는 주로 수치실험 결과와 비교한다. 원주표면의 압력을 구하는 방법에 있어서 기존의 수치해석에서는 주로 방사 운동량방정식만을 사용하였으나, 본 논문에서는 기존의 방법외에 방사 운동량방정식 및 접선 운동량방정식에 의해 압력을 계한하고, 두 값을 비교하여 레이놀즈수에 따른 압력을 구하는 방법을 제시한다. 또한 와도의 분포를 도시하여 원주에 의한 후류의 영향을 받지 않는 외부경계의 한계를 새로이 설정한다.

• 전기학회논문지
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• 제57권10호
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• pp.1696-1702
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• 2008

This paper proposes a voltage compensation device direct control strategy to realize the distributed, autonomous voltage control of the distribution system, which based on voltage data collected from customers of the remote site under the ubiquitous-based distribution system. In the proposed method, The ULTC and the SVR(Step Voltage Regulator)s compensate autonomously the voltage for self-compensation area based on the voltage data furnished from the ubiquitous device of customers. Also, the SVRs overcome the limit of single-operation of ULTC by the interlocking operation with the ULTC and enhance the voltage compensation capability for the customer. In particular, an optimization design method and a fuzzy design method are compared to determine the effective control method of the voltage compensator under the ubiquitous-based on-line operation environments. In fuzzy method, the tap of voltage compensator is defined as output member. Finally, the proposed two methods are implemented in Visual C++ MFC, the effectiveness is proved by simulation based on the worst virtual voltage data. Also, an optimal voltage compensation strategy is determined under on-line environments based on analyzed results.

• Journal of Microbiology and Biotechnology
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• 제14권3호
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• pp.612-619
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• 2004

A competitive direct enzyme-linked immunosorbent assay (cdELISA) was developed for selective and rapid detection of a glycopeptide antibiotic, teicoplanin (TP). TP was conjugated to bovine serum albumin (BSA) for use as an immunogen. Repeated subcutaneous injections of 0.5 mg of the conjugate was effective in generating specific polyclonal antibody (PAb) toward TP in rabbits, as determined by cdELISA. TP-horseradish peroxidase conjugate (TP-HRP) was used as an enzyme marker. The cdELISA was developed based on a competition reaction between TP-BSA PAb and TP-HRP conjugate. The TP-BSA PAb was highly sensitive (detection limit, 0.3 ng/ml and specific toward teicoplanin, showing no cross-reactivity to other glycopeptide antibiotics including vancomycin. There were good correlations ($r^2$=0.84 and 0.76, respectively) between cdELISA and microbiological assay, and high-performance liquid chromatography. The cdELISA system developed in this work is expected to be useful not only for selective and rapid monitoring of TP but also for study of TP pharmacokinetics.

• 환경위생공학
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• 제21권4호
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• pp.29-38
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• 2006

This study included the development of analytical method for determining perchlorate in water sample. The analytical condition was referred in EPA 314.0 method which use ion chromatography and the concentrator column was replaced by the guard column. Concentrating 10mL raw or treated water sample on to AGl6 guard column made it possible to get the LOD(Limit of Detection) of $0.73\;{\mu}g/L$. The total run time was 11 minutes and during run time next sample could be concentrated on AGl6 guard column. Compared to the Concentration method which needed manual operation, the Direct Injection method could screen the many water samples. The LOD of the Direct Injection method was higher and the sensitivity was lower than that of the Concentration method. The RSDs(Relative Standard Deviations) were lower than 2.5 % for peak height and 0.7 % for retention time in pre-concentration methods. This method Showed good reproducibility and reliability and it was thought the deviations of recovery value could be reduced by considering column capacity and making water sample homogeneous. Matrix Elimination could be done using the pre-concentration method if perchlorate were in complex matrix of sample.

• 물과 미래
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• 제31권4호
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• pp.291-297
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• 1998

2차원 흐름이 원주주위를 지날 때 발생하는 흐름의 변화가 기본방정식인 연속방정식과 운동량방정식에 의하여 수치적으로 해석된다. 수채해석 과정은 기본방정식에 유함수, 와도 및 흐름의 특성을 나타내는 무차원 매개변수를 도입하여 무차원 유함수-와소수송식을 유도한후, successive over relaxation scheme과 alternating direct implicit scheme으로 수행된다. 수치실험은 레이놀즈수 125-275를 갖는 흐름에 대하여 수행되었으며, 시간에 따른 유선, 와도, 원주표면의 압력을 구하는 방법에 있어서 기존의 수치해석에서는 주로 방사 운동량방정식만을 사용하였으나, 본 논문에서는 기존의 방법외에 방사 운동량방정식 및 접선 운동량방정식에 의해 압력을 계한하고, 두값을 비교하여 레이놀즈수에 따른 압력을 구하는 방법을 제시한다. 또한 와도의 분포를 도시하여 원주에 의한 후류의 영향을 받지 않는 외부경계의한계를 새로이 설정한다.

• 전기학회논문지
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• 제64권2호
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• pp.232-239
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• 2015

Faced with unbalanced grid operation mode, the high voltage direct current (HVDC) based on voltage source converter (VSC) can be properly controlled by a dual current control scheme. For the modular multilevel converter (MMC) controlling the AC side current is able to limit the arm current which flows along the IGBT of submodule (SM) to rated current. However the limitation of the arm current results in leaving the control range of active power at MMC confined to below the rated capacity. As a result, limiting the arm current causes the problem that the DC side voltage of the HVDC can not be controlled to the reference value since MMC HVDC adjusts the DC side voltage through the active power. In this paper, we propose the algorithm adjusting the active powers of both MMCs to resolve the problem. The back-to-back MMC HVDC applying the algorithm is modeled by PSCAD/EMTDC to verify the algorithm.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제19권2호
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• pp.83-95
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• 2016

Hepatitis C virus (HCV) infection is a major medical challenge affecting around 200 million people worldwide. The main site of HCV replication is the hepatocytes of the liver. HCV is a positive enveloped RNA virus from the flaviviridae family. Six major HCV genotypes are implicated in the human infection. In developed countries the children are infected mainly through vertical transmission during deliveries, while in developing countries it is still due to horizontal transmission from adults. Minimal nonspecific and brief symptoms are initially found in approximately 15% of children. Acute and chronic HCV infection is diagnosed through the recognition of HCV RNA. The main objective for treatment of chronic HCV is to convert detected HCV viremia to below the detection limit. Children with chronic HCV infection are usually asymptomatic and rarely develop severe liver damage. Therefore, the benefits from current therapies, pegylated-Interferon plus ribavirin, must be weighed against their adverse effects. This combined treatment offers a 50-90% chance of clearing HCV infection according to several studies and on different HCV genotype. Recent direct acting antiviral (DAA) drugs which are well established for adults have not yet been approved for children and young adults below 18 years. The most important field for the prevention of HCV infection in children would be the prevention of perinatal and parenteral transmission. There are areas of focus for new lines of research in pediatric HCV-related disease that can be addressed in the near future.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 2003년도 춘계학술대회논문집
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• pp.368-373
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• 2003

This paper presents a study of low frequencies volume velocity vibration control of a smart panel in order to reduce sound transmission. A distributed piezoelectric quadratically shaped polyvinylidene fluoride (PVDF) polymer film is used as a uniform force actuator and an array of 4$\times$4 accelerometer is used as a volume velocity sensor for the implementation of a single-input single-output con rot system. The theoretical and experimental study of sensor-actuator frequency response function sho vs that this sensor-actuator arrangement provides a required strictly positive real frequency response function below about 900Hz. Direct velocity feedback could therefore be implemented with a limited gain which gives reductions of about 15㏈ in vibration level and about 8 ㏈ in acoustic power level at the (1, 1) mode of the smart Panel. It has been also shown that the shaping error of PVDF actuator could limit he stability and performance of the control system.

• Bulletin of the Korean Chemical Society
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• 제30권2호
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• pp.454-458
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• 2009

Polypyrrole (PPy) nanotubes have been synthesized by chemical oxidative polymerization of pyrrole within the pores of polycarbonate membrane using the technology of diffusion of solutes. The nanotubes array prepared by the proposed method can be considered as nanoelectrode ensembles (NEEs). An amperometric uric acid sensor based on PPy NEEs has been developed and used for determination of uric acid in human serum samples. The electrode can direct response to uric acid at potential of 0.60V vs. SCE with wide linear range of $1.52{\times}10^{-6}\;to\;1.54{\times}10^{-3}\;M.\;The\;detection\;limit\;is \;3.02{\times}10^{-7}$ M. This sensor has been used to determine uric acid in real serum samples. PPy NEEs is thought of as a good application in the foreground.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2006년도 추계학술대회 논문집 전기물성,응용부문
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• pp.93-94
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• 2006

In this research, the enhancement of electron-transfer activity of hemoglobin (Hb) in dodecanoic acid film was investigated for the first time. This type of composite film was made on glassy carbon electrode by casting method. Cyclic voltammetric result of the modified electrode displays a well defined redox peaks which was attributed to the direct electrochemical response of Rb. Our results illustrate that Rb exchange electrons directly with electrode and exhibits the characteristics of peroxidase. When we apply this modified electrode as a biosensor, it gives excellent performances in the electrocatalytic reduction of hydrogen peroxide ($H_{2}O_{2}$). Through the optimal conditions, the proposed biosensor shows the linear range for H2O2 determination was from $1{\times}10^{-5}$ to $1.25{\times}10^{-4}mol/L$ with a detection limit of $1{\times}10^{-7}mol/L$. The biosensor retained more than 90% of the initial response after 14 days.