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http://dx.doi.org/10.5012/bkcs.2009.30.2.454

Direct Determination of Uric Acid in Human Serum Samples Using Polypyrrole Nanoelectrode Ensembles  

Yang, Guangming (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Tan, Lin (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Shi, Ya (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Wang, Suiping (State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University)
Lu, Xuxiao (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Bai, Huiping (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Yang, Yunhui (College of Chemistry and Chemical Engineering, Yunnan Normal University)
Publication Information
Bulletin of the Korean Chemical Society / v.30, no.2, 2009 , pp. 454-458 More about this Journal
Abstract
Polypyrrole (PPy) nanotubes have been synthesized by chemical oxidative polymerization of pyrrole within the pores of polycarbonate membrane using the technology of diffusion of solutes. The nanotubes array prepared by the proposed method can be considered as nanoelectrode ensembles (NEEs). An amperometric uric acid sensor based on PPy NEEs has been developed and used for determination of uric acid in human serum samples. The electrode can direct response to uric acid at potential of 0.60V vs. SCE with wide linear range of $1.52{\times}10^{-6}\;to\;1.54{\times}10^{-3}\;M.\;The\;detection\;limit\;is \;3.02{\times}10^{-7}$ M. This sensor has been used to determine uric acid in real serum samples. PPy NEEs is thought of as a good application in the foreground.
Keywords
Uric acid; Sensor; Polypyrrole nanotubes; Polycarbonate membrane; Diffusion;
Citations & Related Records
Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By Web Of Science : 6  (Related Records In Web of Science)
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