• Water for future
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• v.21 no.3
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• pp.291-291
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• 1988

The two dimensional time dependent flow past a circular cylinder is analyzed numerically. In the analysis, equations of conservation of mass and momentum are transformed to equations of stream function-vorticity and vorticity transport, and nondimensionalized by nondimensional parameters representing flow characteristics, The resulting stream function-vorticity equstion and vorticity transport equation are solved by successive over relaxation scheme and alternating direct implicit scheme. Numerical experments are performed for the flow in the range of Reynolds number 125 to 275. The time dependent streamlines, vorticities, pressure on cylinder surface, separation angle, and drag and lift coefficients are calculated, and the method for estimation of pressure on cylinder surface and the outer boundary limit are developed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.57 no.10
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• pp.1696-1702
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• 2008

This paper proposes a voltage compensation device direct control strategy to realize the distributed, autonomous voltage control of the distribution system, which based on voltage data collected from customers of the remote site under the ubiquitous-based distribution system. In the proposed method, The ULTC and the SVR(Step Voltage Regulator)s compensate autonomously the voltage for self-compensation area based on the voltage data furnished from the ubiquitous device of customers. Also, the SVRs overcome the limit of single-operation of ULTC by the interlocking operation with the ULTC and enhance the voltage compensation capability for the customer. In particular, an optimization design method and a fuzzy design method are compared to determine the effective control method of the voltage compensator under the ubiquitous-based on-line operation environments. In fuzzy method, the tap of voltage compensator is defined as output member. Finally, the proposed two methods are implemented in Visual C++ MFC, the effectiveness is proved by simulation based on the worst virtual voltage data. Also, an optimal voltage compensation strategy is determined under on-line environments based on analyzed results.

• Journal of Microbiology and Biotechnology
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• v.14 no.3
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• pp.612-619
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• 2004

A competitive direct enzyme-linked immunosorbent assay (cdELISA) was developed for selective and rapid detection of a glycopeptide antibiotic, teicoplanin (TP). TP was conjugated to bovine serum albumin (BSA) for use as an immunogen. Repeated subcutaneous injections of 0.5 mg of the conjugate was effective in generating specific polyclonal antibody (PAb) toward TP in rabbits, as determined by cdELISA. TP-horseradish peroxidase conjugate (TP-HRP) was used as an enzyme marker. The cdELISA was developed based on a competition reaction between TP-BSA PAb and TP-HRP conjugate. The TP-BSA PAb was highly sensitive (detection limit, 0.3 ng/ml and specific toward teicoplanin, showing no cross-reactivity to other glycopeptide antibiotics including vancomycin. There were good correlations ($r^2$=0.84 and 0.76, respectively) between cdELISA and microbiological assay, and high-performance liquid chromatography. The cdELISA system developed in this work is expected to be useful not only for selective and rapid monitoring of TP but also for study of TP pharmacokinetics.

• Journal of environmental and Sanitary engineering
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• v.21 no.4 s.62
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• pp.29-38
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• 2006

This study included the development of analytical method for determining perchlorate in water sample. The analytical condition was referred in EPA 314.0 method which use ion chromatography and the concentrator column was replaced by the guard column. Concentrating 10mL raw or treated water sample on to AGl6 guard column made it possible to get the LOD(Limit of Detection) of $0.73\;{\mu}g/L$. The total run time was 11 minutes and during run time next sample could be concentrated on AGl6 guard column. Compared to the Concentration method which needed manual operation, the Direct Injection method could screen the many water samples. The LOD of the Direct Injection method was higher and the sensitivity was lower than that of the Concentration method. The RSDs(Relative Standard Deviations) were lower than 2.5 % for peak height and 0.7 % for retention time in pre-concentration methods. This method Showed good reproducibility and reliability and it was thought the deviations of recovery value could be reduced by considering column capacity and making water sample homogeneous. Matrix Elimination could be done using the pre-concentration method if perchlorate were in complex matrix of sample.

• Water for future
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• v.31 no.4
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• pp.291-297
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• 1998

The two dimensional time dependent flow past a circular cylinder is analyzed numerically. In the analysis, equations of conservation of mass and momentum are transformed to equations of stream function-vorticity and vorticity transport, and nondimensionalized by nondimensional parameters representing flow characteristics, The resulting stream function-vorticity equation and vorticity transport equation are solved by successive over relaxation scheme and alternating direct implicit scheme. Numerical experiments are performed for the flow in the range of Reynolds number 125 to 275. The time dependent streamlines, vorticities, pressure on cylinder surface, separation angle, and drag and lift coefficients are calculated, and the method for estimation of pressure on cylinder surface and the outer boundary limit are developed.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.64 no.2
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• pp.232-239
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• 2015

Faced with unbalanced grid operation mode, the high voltage direct current (HVDC) based on voltage source converter (VSC) can be properly controlled by a dual current control scheme. For the modular multilevel converter (MMC) controlling the AC side current is able to limit the arm current which flows along the IGBT of submodule (SM) to rated current. However the limitation of the arm current results in leaving the control range of active power at MMC confined to below the rated capacity. As a result, limiting the arm current causes the problem that the DC side voltage of the HVDC can not be controlled to the reference value since MMC HVDC adjusts the DC side voltage through the active power. In this paper, we propose the algorithm adjusting the active powers of both MMCs to resolve the problem. The back-to-back MMC HVDC applying the algorithm is modeled by PSCAD/EMTDC to verify the algorithm.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.19 no.2
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• pp.83-95
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• 2016

Hepatitis C virus (HCV) infection is a major medical challenge affecting around 200 million people worldwide. The main site of HCV replication is the hepatocytes of the liver. HCV is a positive enveloped RNA virus from the flaviviridae family. Six major HCV genotypes are implicated in the human infection. In developed countries the children are infected mainly through vertical transmission during deliveries, while in developing countries it is still due to horizontal transmission from adults. Minimal nonspecific and brief symptoms are initially found in approximately 15% of children. Acute and chronic HCV infection is diagnosed through the recognition of HCV RNA. The main objective for treatment of chronic HCV is to convert detected HCV viremia to below the detection limit. Children with chronic HCV infection are usually asymptomatic and rarely develop severe liver damage. Therefore, the benefits from current therapies, pegylated-Interferon plus ribavirin, must be weighed against their adverse effects. This combined treatment offers a 50-90% chance of clearing HCV infection according to several studies and on different HCV genotype. Recent direct acting antiviral (DAA) drugs which are well established for adults have not yet been approved for children and young adults below 18 years. The most important field for the prevention of HCV infection in children would be the prevention of perinatal and parenteral transmission. There are areas of focus for new lines of research in pediatric HCV-related disease that can be addressed in the near future.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.368-373
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• 2003

This paper presents a study of low frequencies volume velocity vibration control of a smart panel in order to reduce sound transmission. A distributed piezoelectric quadratically shaped polyvinylidene fluoride (PVDF) polymer film is used as a uniform force actuator and an array of 4$\times$4 accelerometer is used as a volume velocity sensor for the implementation of a single-input single-output con rot system. The theoretical and experimental study of sensor-actuator frequency response function sho vs that this sensor-actuator arrangement provides a required strictly positive real frequency response function below about 900Hz. Direct velocity feedback could therefore be implemented with a limited gain which gives reductions of about 15㏈ in vibration level and about 8 ㏈ in acoustic power level at the (1, 1) mode of the smart Panel. It has been also shown that the shaping error of PVDF actuator could limit he stability and performance of the control system.

• Bulletin of the Korean Chemical Society
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• v.30 no.2
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• pp.454-458
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• 2009

Polypyrrole (PPy) nanotubes have been synthesized by chemical oxidative polymerization of pyrrole within the pores of polycarbonate membrane using the technology of diffusion of solutes. The nanotubes array prepared by the proposed method can be considered as nanoelectrode ensembles (NEEs). An amperometric uric acid sensor based on PPy NEEs has been developed and used for determination of uric acid in human serum samples. The electrode can direct response to uric acid at potential of 0.60V vs. SCE with wide linear range of $1.52{\times}10^{-6}\;to\;1.54{\times}10^{-3}\;M.\;The\;detection\;limit\;is \;3.02{\times}10^{-7}$ M. This sensor has been used to determine uric acid in real serum samples. PPy NEEs is thought of as a good application in the foreground.

• Proceedings of the KIEE Conference
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• 2006.10a
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• pp.93-94
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• 2006

In this research, the enhancement of electron-transfer activity of hemoglobin (Hb) in dodecanoic acid film was investigated for the first time. This type of composite film was made on glassy carbon electrode by casting method. Cyclic voltammetric result of the modified electrode displays a well defined redox peaks which was attributed to the direct electrochemical response of Rb. Our results illustrate that Rb exchange electrons directly with electrode and exhibits the characteristics of peroxidase. When we apply this modified electrode as a biosensor, it gives excellent performances in the electrocatalytic reduction of hydrogen peroxide ($H_{2}O_{2}$). Through the optimal conditions, the proposed biosensor shows the linear range for H2O2 determination was from $1{\times}10^{-5}$ to $1.25{\times}10^{-4}mol/L$ with a detection limit of $1{\times}10^{-7}mol/L$. The biosensor retained more than 90% of the initial response after 14 days.