• Journal of Digestive Cancer Research
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• 제2권1호
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• pp.5-7
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• 2014

Screening and early diagnosis of cancer is important. Screening lead to detect disease earlier, and earlier treatment of disease cause to yield a better outcome than treatment at the onset of symptoms. Some studies suggest that gastric cancer screening may be associated with a reduced risk of mortality from gastric cancer, although there are no definitive data from large controlled trials. Regular colorectal cancer screening or testing is one of the most powerful weapons for preventing colorectal cancer, because some polyps, or growths can be found and removed before they have the chance to turn into cancer. Screening can also result in finding colorectal cancer early, when it is highly curable. In conclusion, to increase utilization of screening is important to decrease gastric and colorectal cancer morbidity and mortality.

• 대한한방소아과학회지
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• 제18권2호
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• pp.119-126
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• 2004

Objective : We used herbal medicine to treat various disease and also to keep good general condition of children. We aimed to evaluate the effect of herbal medicine on the growth of children treated with herbal medicine. Method: We studied 187 children who visited the department of Pediatrics, KyungHee Oriental Medical Hospital from March 2004 to August 2004. They meet condition as follows; they were treated for more than 6 months and they visited our clinic more than 3 times. Whenever patients visited our hospital, we measured their height, body weight and obesity degree using DS-102(dszenix, Seoul). We measured height percentile of first time visit, and that of last time visit. And we compared them using the Growth Statistics Curve made by the Korean Association of Pediatrics, 1998. Results : The mean growth of total children showed 4.04 percentile upwardly; the growth- up percentile of boys was 4.52 and that of girls was 3.26. Analysis according to disease resulted as follows; children with respiratory disease showed 10.29 percentile growth-up, digestive disease 4.21percentile, urinary disease 4 percentile, allergic disease 2.65 percentile, weak children 2.52 percentile and other disease 3.19 percentile. Conclusion : Herbal medical treatment helped growth not only in children who took medicine for growth retardation problem but children with various disease. Moreover herbal medical treatment applied to keep good general condition of children also gave positive effect on the growth of children.

• 대한한의학원전학회지
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• 제29권1호
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• pp.139-172
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• 2016

Objectives : The purpose of research thesis is an advanced interpretation of the Name of Constitutional Disease of Dong-uisusebowon(東醫壽世保元) 1901 edition(辛丑本) evaluated to interpretation incompleted, and application of clinical diagnosis by rivised interpretation. Methods : A study on translation of sasangin(四象人)'s constitutional disease is researched the methods of documentary research on Dong-uisusebowon(東醫壽世保元) 1901 edition(辛丑本) and 1894 edition(甲午本). Results : Result of analysis of 4 meaning unit is as follows. Viscera or entrails means root or terminus of organ whom getting disease. Cold or heat based means being chilled or hot of triple energizer. Eexterior or interior means origin of disease of exterior or interior. Cold or heat means being chilled or hot of digestive system. Conclusions : In the clinical diagnosis using revised interpretaion, diagnosis of exterior or interior disease can be decided by symptoms of Taeyang syndrome(太陽病)'s fever and aversion to cold or not. Diagnosis of cold or heat disease can be decided by diarrhea or constipation.

• 대한본초학회지
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• 제37권6호
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• pp.45-52
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• 2022

Objective : In this study, we conducted to analysis the patents about Korean medicine based treatment technology for pet. Methods : We collected the Korean, Japan, USA, China, EU and PCT patent for the Korean medicine-based treatment technology for pet using WIPSON data base registered by October 4, 2020 were selected. Results : Patents for the development of pet Korean medicine-based treatment technology have been constantly applied since the mid-2000s, starting in 1990, with a total of 84 applications. The number of patent applications filed in Korea was the largest, after Japan and China. The detailed composition of the applications reported until now is pharmaceutical compositions for the treatment of pet were the most applied with 39%(33 cases), followed by feed used as stocks for pet at 36%(30 cases). According to the patent application rate by disease, most of applications rate composed to be associated with immunity in 2009 to 2013 with 40% of applications. In 2014 to 2018 43% of patent applications are associated with gastrointestinal/digestive system. In this regard, multiple applications were filed in the order of immunity, digestive system, obesity and urinary system. Conclusion : This study analyzed the trend of 84 patents about Korean medicine-based treatment technology for pet to date to establish the basis for future research and development. There were many applications related to immunity from 2009 to 2013, and since then, related to digestive disease from 2014 to 2018.

• 농촌의학ㆍ지역보건
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• 제21권2호
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• pp.243-251
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• 1996

Authors surveyed the inhabitants in Ulnung Island to assess the patterns of medical utilization. One hundred eighty six population(65 male and 121 female) were surveyed with formed questionnaire from Aug. 16 to Aug. 19 in 1994. Results are as follows. 1. The prevalence rate of acute diseases was 19.3%. 2. The prevalence rate of chronic diseases was 35.0%. In classification of chronic disease, the disease of musculoscletal system was the highest(33.9%) and that of digestive system in next order. 3. The first-visit medical facility when disease developed was community health center mainly. The admission care was taken in 37.6%. The 80.0% among location of medical facility for admission care was out of island. The surgical operative care were taken in 19.9%. The 86.5% among location of medical facility for surgical operative care was out of island. 4. Among the contents of dissatisfaction for medical service within island, 'Insufficient equipment' was the highest(35.8%), and 'Insufficient traffic networks' in next order. The results of this study suggest that public health facilities and medical personnel be strengthened and emergency transfer system be secured in Ulnung Island.

• 항공우주의학회지
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• 제30권1호
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• pp.40-49
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• 2020

In accordance with ICAO SARPs, the states should implement appropriate aviation-related health promotion for airmen subject to an aviation medical examination to reduce future medical risks to flight safety. We aimed to analyze the results of the aviation medical examination to use as objective evidence for establishing an aviationrelated health promotion plan. The results of the final issuance of airmen medical certificate from 2015~2017 were collected from the e-sky computer system. The 30 cases (0.3%) in 2015, 22 cases (0.2%) in 2016, 38 cases (0.3%) in 2017 were unfit for flight duty. The 34 unfit out of the total 90 cases were renewal physical examinations. The cardiovascular disease was most commonly in 11 cases, followed by 8 tumors, 4 psychiatric diseases, 3 ophthalmic diseases, 2 respiratory diseases, 2 neurologic diseases, 2 otolaryngological diseases, 1 endocrine disease and 1 digestive disease. The results of this study can be used as objective data in aviation-related health promotion plan. The health promotion activities based on objective data can contribute to improving aviation safety by improving the lifestyles of airmen.

• 사상체질의학회지
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• 제33권4호
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• pp.57-64
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• 2021

Objectives This study was aimed to report significant improvement of gastroesophageal reflux disease (GERD) treated by Cheongsimyeonja-tang and acupuncture treatment in Taeeumin. Methods Patient who has GERD was treated with herbal medicine and acupunture from June 15 to July 6. Gastrointestinal Symptom Rating Scale (GSRS) was used to observe changes of digestive symptoms. Results After treatment, the GSRS of the patient improved from 4.8 to 2.6. Also, the patient's symptoms of sore throat, cough, phlegm and bowel sound were reported to be improved after treatment. Conclusions This study shows that Cheongsimyeonja-tang might be effective in Taeeumin type patient's GERD.

• Journal of Digestive Cancer Research
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• 제4권2호
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• pp.127-129
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• 2016

The prognosis for pancreatic cancer patient is very poor. Patients with locally advanced disease have a median survival time of 8 to 12 months, and patients with distant metastases have significantly worse outcomes, with a median survival time of only 3 to 6 months. Approximately 30% of patients with pancreatic cancer present with locally advanced disease defined as unresectable pancreatic cancer without evidence of distant metastatic disease. Primary treatment options in locally advanced pancreatic cancer include chemotherapy and radiotherapy. Here, we reported a patient with locally advanced pancreatic cancer who does not want further chemotherapy because of chemotherapy induced nausea and vomiting. Irreversible electroporation was performed. Irreversible electroporation was well tolerated in this case, and may be a therapeutic modality for selected patients with locally advanced pancreatic cancer.

• 한국산학기술학회논문지
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• 제20권1호
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• pp.162-169
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• 2019

본 연구는 65세 미만 성인과 65세 이상 노인에서 고혈압 위험요인을 파악하기 위한 서술적 조사연구이다. 6차 고령화 연구패널조사를 활용하여 6,152명의 연구대상자를 분석하였으며, 수집된 자료는 SPSS 23을 이용하여 카이검정과 로지스틱 회귀분석을 시행하였다. 고혈압 유병률에 영향을 미치는 위험요인에 대한 로지스틱 회귀분석 결과는 65세 미만 성인과 65세 이상 노인 둘 다에서, 주관적 건강상태, 당뇨병 유무, 심장질환 유무, BMI에 따른 비만정도가 위험요인으로 나타났고, 65세 미만에서는 만성폐질환, 소화기계 질환, 음주가, 65세 이상에서는 거주지역, 관절염 및 류마티스 질환, 흡연, 인지기능 정도가 고혈압에 영향을 미치는 위험요인으로 나타났다. 우리나라는 급속한 고령화 현상으로 인해 체계적이고 정책적인 만성질환관리가 절실하다. 특히, 나이에 따라 꾸준히 증가하는 고혈압에 대한 효과적인 관리를 위해 연령대에 따른 위험요인을 분석하는 것은 중요하다. 따라서 개인적 노후준비 뿐만 아니라 전반적인 사회복지수준 향상 및 노인복지대책을 통해 질병에 대한 관리가 필요하다.

• The Korean Journal of Physiology and Pharmacology
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• 제27권4호
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• pp.365-374
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• 2023

Crohn's disease (CD) is a chronic inflammatory illness of the digestive system with unknown etiology, and its incidence is increasing worldwide. However, there are currently no effective treatments or medications available for individuals with CD. Therefore, novel therapeutic strategies are urgently needed. The bioactive compounds and targets associated with compounds of Qinghua Xiaoyong Formula (QHXYF) were examined using The Traditional Chinese Medicine Systems Pharmacology database, and 5 disease target databases were also used to identify CD-related disease targets. A total of 166 overlapping targets were identified from QHXYF-related and CD-related disease targets and they were found to be enriched in oxidative stress-related pathways and the PI3K/AKT signaling pathway. Molecular docking was then used to predict how the bioactive compounds would bind to the hub targets. It was found that quercetin could be the core bioactive compound and had good binding affinity to the top 5 hub targets. Finally, animal experiments were performed to further validate the findings, and the results revealed that QHXYF or quercetin inhibited 2,4,6-trinitrobenzenesulfonic acid-induced inflammation and oxidative stress processes by inhibiting the PI3K/AKT pathway, thereby improving CD symptoms. These findings suggest that QHXYF and quercetin may be potential novel treatments for CD.