• Title/Summary/Keyword: differential media

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Development of New Amlodipine Complex using Ion Exchange Resin (이온교환수지를 이용한 새로운 암로디핀 복합체 개발)

  • Jeong, Sang-Young;Ahn, Ki-Young;Ahn, Geon-Seok;Gil, Young-Sig;Hwang, Sung-Joo
    • Journal of Pharmaceutical Investigation
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    • v.38 no.1
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    • pp.9-14
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    • 2008
  • Cation exchange resin complex of amlodipine free base has been investigated to improve the stability and dissolution profile. The complex was prepared by reacting amlodipine solution with activated cation exchange resin, and amlodipine content in the complex was 31.6% calculated by HPLC determination. Its product was not physical mixture but the complex formed by ionic bond, which was identified by microscope system, differential scanning calorimetry and X-ray diffractometry. Each tablet containing amlodipine free base(I) and its complex(II) was prepared for the accelerated stability test ($40^{\circ}C$, 75%RH) and dissolution test in the pH 1.2 buffer solution and purified water media. Dissolution patterns of formulation II in both media were similar to those of $Norvasc^{(R)}$ tablet, but the pattern of formulation I in purified water was different. After 6 months storage under stability test, amlodipine content of formulation I, II and $Norvasc^{(R)}$ tablet were $99.3{\pm}1.2%,\;98.9{\pm}1.4%\;and\;83.9{\pm}3.4%$, respectively. While amlodipine free base was unstable at the condition, its complex was not only significantly stable, but also similar in the dissolution pattern. These results suggest the usefulness of complex as a stable carrier for amlodipine free base.

The Moderating Effect of Perceived Control over Appearance in the Social Comparison Process with Advertisement Models (광고모델과의 사회적 비교과정에서 외모통제력 지각이 갖는 조정효과)

  • Lee Yoon-Jung
    • Journal of the Korean Society of Clothing and Textiles
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    • v.30 no.4 s.152
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    • pp.633-643
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    • 2006
  • When women are exposed to images of other attractive women such as media models, it is known that many go through a social comparison process and a contrast effect occurs which results in unfavorable perception and attitudes toward the self. This paper suggests women's perception of control over their appearance as one of the factors that may moderate the contrast effect of a social comparison with attractive media models. An experiment with 211 women was conducted to examine the differential effect of viewing attractive models versus non-human images on the responses of women with high/low perceived control over appearance. A two(Stimuli Type: attractive-model image vs. non-human image) by two(Perceived Control over Appearance: High vs. Low) MANCOVA model was tested with physical appearance anxiety, self-esteem, and body satisfaction as dependent variables and appearance orientation, body mass index, age, years of schooling, ethnicity, and marital status as covariates. A significant Perceived Control main effect on Physical Appearance Anxiety and Self-Esteem and a significant Stimuli Type by Perceived Control interaction effect on Physical Appearance Anxiety and Self-Esteem were found. Those who perceived high control over their appearance were more likely to have higher self-esteem and lower appearance anxiety. However, among those who saw attractive model's images, women perceived low appearance control showed less anxiety and higher body satisfaction than those perceived high appearance control.

Lifetime Prediction and Aging Behaviors of Nitrile Butadiene Rubber under Operating Environment of Transformer

  • Qian, Yi-hua;Xiao, Hong-zhao;Nie, Ming-hao;Zhao, Yao-hong;Luo, Yun-bai;Gong, Shu-ling
    • Journal of Electrical Engineering and Technology
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    • v.13 no.2
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    • pp.918-927
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    • 2018
  • Based on the actual operating environment of transformer, the aging tests of nitrile butadiene rubber (NBR) were conducted systematically under four conditions: in air, in transform oil, under compression in air and under compression in transform oil to studythe effect of high temperature, transform oil and compression stress simultaneously on the thermal aging behaviors of nitrile butadiene rubber and predict the lifetime. The effects of liquid media and compression stress simultaneously on the thermal aging behaviors of nitrile butadiene rubber were studied by using characterization methods such as IR spectrosc-opy, thermogravimetric measurements, Differential Scanning Calorimetry (DSC) measurements and mechanical property measurements. The changes in physical properties during the aging process were analyzed and compared. Different aging conditions yielded materials with different properties. Aging at $70^{\circ}C$ under compression stress in oil, the change in elongation at break was lower than that aging in oil, but larger than that aging under compression in air. The compression set or elongation at break as evaluation indexes, 50% as critical value, the lifetime of NBR at $25^{\circ}C$ was predicted and compared. When aging under compression in oil, the prediction lifetime was lower than in air and under compression in air, and in oil. It was clear that when predicting the service lifetime of NBR in oil sealing application, compression and media liquid should be involved simultaneously. Under compression in oil, compression set as the evaluation index, the prediction lifetime of NBR was shorter than that of elongation at break as the evaluation index. For the life prediction of NBR, we should take into account of the performance trends of NBR under actual operating conditions to select the appropriate evaluation index.

A Study on Preprocessing Method in Deep Learning for ICS Cyber Attack Detection (ICS 사이버 공격 탐지를 위한 딥러닝 전처리 방법 연구)

  • Seonghwan Park;Minseok Kim;Eunseo Baek;Junghoon Park
    • Smart Media Journal
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    • v.12 no.11
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    • pp.36-47
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    • 2023
  • Industrial Control System(ICS), which controls facilities at major industrial sites, is increasingly connected to other systems through networks. With this integration and the development of intelligent attacks that can lead to a single external intrusion as a whole system paralysis, the risk and impact of security on industrial control systems are increasing. As a result, research on how to protect and detect cyber attacks is actively underway, and deep learning models in the form of unsupervised learning have achieved a lot, and many abnormal detection technologies based on deep learning are being introduced. In this study, we emphasize the application of preprocessing methodologies to enhance the anomaly detection performance of deep learning models on time series data. The results demonstrate the effectiveness of a Wavelet Transform (WT)-based noise reduction methodology as a preprocessing technique for deep learning-based anomaly detection. Particularly, by incorporating sensor characteristics through clustering, the differential application of the Dual-Tree Complex Wavelet Transform proves to be the most effective approach in improving the detection performance of cyber attacks.

Bi-Histogram Equalization based on Differential Compression Method for Preserving the Trend of Natural Mean Brightness (자연스러운 영상의 평균 밝기 유지를 위한 차별적 압축 방법 기반의 분할 히스토그램 평활화)

  • Lee, Jae-Won;Hong, Sung-Hoon
    • Journal of Broadcast Engineering
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    • v.19 no.4
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    • pp.453-467
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    • 2014
  • A typical histogram equalization contrast enhancement effect for improving the image quality is excellent. However, because it appears that excessive changes of the brightness values, The average brightness of the image is changing in units of frames of applications such as a TV video is unsuitable. In order to solve these drawbacks, a modified method of histogram equalization on various studies have been made. But the result images of existing methods sometimes shown visual degradations such as over-enhancement and false contouring. In this paper, we propose improved contrast enhancement method through bi-histogram equalization using target mean brightness based on differential compression method. The proposed method is based on the average brightness value by dividing the histogram, the histogram for each zone, according to the frequency differential of compression. And equalize the modified histogram based on target mean brightness. This allows to suppress deterioration of picture quality, and changes in the average brightness of each frame of video, while maintaining and improving the contrast. Experimental results show that the proposed method compared to the conventional method, the average brightness of each frame from a movie well maintained, and no degradation of the image quality showed a good effect to improve the contrast.

Trace Measurement of Ruthenium by Adsorptive Stripping Voltammetry (벗김 전압전류법에 의한 루테늄의 미량 측정)

  • Czae, Myung Zoon;Kwon, Young Soon;Kim, So Jin
    • Journal of the Korean Chemical Society
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    • v.41 no.5
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    • pp.246-250
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    • 1997
  • In the presence of optimum amounts of hydroxylamine, trace ruthenium(III) can be conveniently determined in acidic (boric) media by coupling catalytic hydrogen processes with adsorptive accumulation of the catalyst, using differential pulse voltammetry. Cyclic voltammetry was used to characterize the redox and interfacial processes. Optimal experimental conditions were found to be a stirred borate (0.015 M, pH 2.5) solution containing 0.55 M hydroxylamine, a preconcentration potential of - 0.70 V, and a scan rate of 5 mV/s. With a 7 min accumulation period the detection limit was 3${\times}$10-10 M. The possible interferences by other platinum group metals are investigated.

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The effect which the location of Partitioning Function causes in successful probability in Differential Power Analysis (차분 전력 분석에서 분류함수의 위치가 성공확률에 미치는 영향)

  • Kim, Sung-Kyoung;Kim, Hee-Seok;Kim, Tae-Hyun;Han, Dong-Guk;Ryoo, Jeong-Choon;Lim, Jong-In
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2007.02a
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    • pp.112-115
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    • 2007
  • 최근 부채널 공격으로 스마트 카드 같은 장치의 비밀키를 알아낼 수 있음이 알려지면서 많은 알고리즘에 대한 부채널 공격과 대웅 방안이 연구되고 있다. 차분전력분석은 부채널 공격의 일종으로 암호화 연산 중 발생하는 전력 소모 곡선을 통계적으로 분석하여 키를 알아내는 공격이다. 본 논문에서는 Hocker 형태의 IC칩 차분전력분석공격에 대한 실험 분석 모델을 설정한 후 이를 검증하고자 축소형 모델로 실험한다 실험 분석을 위하여 선정된 장치에 DES 암호알고리즘을 어셈블리로 구현한 후 8비트 마이크로프로세서 형 칩에 탑재하여 암호 알고리즘 실행 시에 발생되는 차분 전력 신호를 분석한다. 그리고 차분전력분석 공격에서 중요한 기술인 분류함수 설정에 따른 분석 성공 여부에 따른 비교를 한다.

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Morphogenetic Behavior of Tropical Marine Yeast Yarrowia lipolytica in Response to Hydrophobic Substrates

  • Zinjarde, Smita S.;Kale, Bhagyashree V.;Vishwasrao, Paresh V.;Kumar, Ameeta R.
    • Journal of Microbiology and Biotechnology
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    • v.18 no.9
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    • pp.1522-1528
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    • 2008
  • The morphogenetic behavior of a tropical marine Yarrowia lipolytica strain on hydrophobic substrates was studied. Media containing coconut oil or palm kernel oil (rich in lauric and myristic acids) prepared in distilled water or seawater at a neutral pH supported 95% of the cells to undergo a transition from the yeast form to the mycelium form. With potassium laurate, 51 % of the cells were in the mycelium form, whereas with myristate, 32% were in the mycelium form. However, combinations of these two fatty acids in proportions that are present in coconut oil or palm kernel oil enhanced the mycelium formation to 65%. The culture also produced extracellular lipases during the morphogenetic change. The yeast cells were found to attach to the large droplets of the hydrophobic substrates during the transition, while the mycelia were associated with the aqueous phase. The alkane-grown yeast partitioned more efficiently in the hydrophobic phases when compared with the coconut oil-grown mycelia. A fatty acid analysis of the mycelial form revealed the presence of lauric acid in addition to the long-chain saturated and unsaturated fatty acids observed in the yeast form. The mycelia underwent a rapid transition to the yeast form with n-dodecane, a medium-chain aliphatic hydrocarbon. Thus, the fungus displayed a differential behavior towards the two types of saturated hydrophobic substrates.

Biochemical characterization of Bacillus thuringiensis, 23 serovars (Biochemical thuringiensis, 23 serovars의 생화학적 특성)

  • Lee, Hyung-Hoan;Park, Mi-Yeoun;Lee, Chang-Woon
    • Microbiology and Biotechnology Letters
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    • v.14 no.2
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    • pp.205-208
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    • 1986
  • The 23 serovars of Bacillus thuringiensis strain were commonly gram-positive and motile, formed endotoxin crystals, produced acid and alkali in the KIA media, and acid from glucose, hydrolyzed starch, and reduced nitrate but did not produce H$_2$S, oxidase and indole, did not decompose lysine, ornithine, phenylalanine, malonate, lactose, dulcitol, adonitol, inositol, sorbitol, arabinose, raffinose, rhamnose, maltose, and xylose. Eighteen serovars were positive in the MR tests and 15 in the VP tests. Four serovars used citrate. Five serovars produced urease, 5 $CO_2$ from glucose, 2 DNase, and 15 lecithinase. Twelve serovars decomposed arginine, 11 did sucrose, 2 manitol, and 9 salicin Serovar tohokuensis did not hemolyze, but the others did.

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Isolation and Identification of Cellulose-Producing Bacteria (Microbial Cellulose 생산세균의 분리 및 동정)

  • 손홍주;이오미;김용균;이상준
    • Microbiology and Biotechnology Letters
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    • v.28 no.3
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    • pp.134-138
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    • 2000
  • Extensive screening for cellulose-producing bacteria was done using differential media. Fifty seven strains were isolated totally from the fruits and the vinegar, respectively; the isolate A9 strain from apples was selected and examined to determine its taxonomical characteristics. The bacterium was identified as the genus Acetobacter sp_ based on morphological, cultural and biochemical properties. A9 strain produced acetic acid from ethanol and decomposed acetic acid to $CO_2$ and $H_2O$. They produced dihydroxyacetone from glycerol but did not produce y-pyrone from glucose and fructose. When A9 strain was cultivated statically in Hestrin and Schramm liquid medium(HS medium). thick cellulose pellicle was formed_ Higher cellulose production was obtained in the shaken culture using HS medium at 100 rpm.

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