• Journal of the Korean Wood Science and Technology
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• 제31권1호
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• pp.61-70
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• 2003

원심법을 이용하여 침엽수 생재 심재부의 조재와 만재에 대한 수분이동경로의 크기를 평가하였다. 또한, 원심처리 후의 포수율 분포와 수분포텐셜의 관계로부터 액체투과성을 측정하였다. 삼나무의 경우, 조재는 0.70 ㎛, 만재는 0.50 ㎛의 반경에서 뚜렷한 피크가 관찰되었다. 솔송나무는 조재와 만재 모두 0.50 ㎛의 반경에서 피크를 나타냈다. 일본전나무와 일본잎갈나무는 조재 0.70 ㎛, 만재 0.30 ㎛의 반경범위에서 피크 값이 관찰되었다. 반면에, 미송과 시트카스푸르수는 뚜렷한 피크 값을 보이지 않았다. 액체투과성은 미송을 제외한 모든 수종에서 조재가 만재보다 좋게 평가되었다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제26권4호
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• pp.355-362
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• 2000

Neoplastic growth is characterized by alterations of oncogenes and antioncogenes. The interaction between activated oncogenes and functional deletion of antioncogene appears to be the driving force directing normal cells to uncontrolled growth resulting in tumor. In addition to those genes mentioned, other genes controlling the entry of cells into the cell cycle have recently been implicated in cancer development. The overexpression of the cyclin D1 gene, which has been mapped to 11q13, either by gene rearrangement or amplification has been noted in various malignant tumors. The product of the cyclin D1 gene forms a complex with cyclin-dependent protein kinases(CDK4) that governs a key transition in the cell cycle. The relationships between the overexpression of cyclin D1 assessed by immunihistochemistry and the amplification of the cyclin D1 gene by differential polymerase chain reaction(DPCR) using primers for dopamin D2 receptor gene in 13 cases of squamous cell carcinomas of the oral cavity have been studied. The semiquantitative assay of cyclin D1 amplification has been made by cyclin D1/dopamin D2 receptor(CD/DR) ratio. The results were as follows; 1. In the normal tissue and the tumor, the CD/DR ratios were 0.82 and 1.36 respectively. This implicates 1.65-fold amplification of cyclin D1 gene in tumor compared to that in normal tissue. 2. The tumor tissue which showed overexpression of cyclin D1 by immunohistochemistry revealed 2-fold amplification of cyclin D1 compared to the normal tissue. 3. The tumor tissue which showed mild expression of cyclin D1 by immunihistochemistry revealed 1.7-fold amplification of cyclin D compared to the normal tissue. 4. The cyclin D1 was overexpressed in the tumor tissue at the rate of 38%. Above results suggest that cyclin D1 has close correlation with the development of carcinoma in the oral cavity. But further studies were needed to elucidate the carcinogeneic mechanisms by comparative studies among cyclin D1, pRb and p53.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2002년도 하계학술대회 논문집 B
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• pp.773-775
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• 2002

This paper deals with 3 Dimensional(3D) analysis of magnetic flux density of High Temperature Superconducting(HTS) motor using 3D Equivalent Magnetic Circuit Network (EMCN). When the Finite Element Method (FEM) is applied to an analysis of 3D models, it takes much time to the pre-process work required for 3D modeling and to solve the differential equation. Compare with 3D FEM, the result of 3D EMCN by using the magnetic resistance and magnetomotive force is exact and rapid. The accuracy of 3D EMCN is verified by comparing the 3D EMCN analysis with that of 3D FEM in HTS motor.

• 한국지반공학회지:지반
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• 제8권1호
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• pp.41-58
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• 1992

본 연구에서는 항만공사에 이용되는 앵커로 지지된 널말뚝의 내진설계를 위한 해석방법의 제시가 이루어 졌다. 제시된 해석방법은 지진하중시의 동수압을 포함하였으며, 침투에 의한 영향을 고려할 경우에도 적용이 가능하다. 또한 적용범 위는 모래 및 점성토(c-0 soil)로 이루어진 지반의 경우이고, 자유지지법을 토대로 하였다. 아울러, 널말뚝 양쪽면의 수위차, 앵커의 위치, 벽마찰각, 준설저면의 경사각, 부착력, 점착력 등이 근입깊이, 앵커하중 및 최대모멘트에 미치는 영향을 제시된 해석방법을 토대로 분석하였다. 이외에도 서로 다른 안전율 정의에 관한 비교 및 내진설계시의 유의 사항에 대한 검토가 이루어 졌다.

• 한국지반공학회:학술대회논문집
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• 한국지반공학회 2003년도 봄 학술발표회 논문집
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• pp.103-110
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• 2003

This study is as for shale that attract recently geotechnical engineer more and more. like sedimentary rocks and metamorpic rocks, shales have many problem with anisotropy for stength and deformation and they have many problems with quick weathering progress and differential weathering of alternate bedding. In foreign countries, many renowned schalors, like Jaeger(1960),McLamore,Gray(1967),Donath(1972),Nova(1980),Hoek&Brown(1980),Ranamurthy(1985), have already studied for a variety of characteristic and announced high level results of their studies. In domestic also, there are many scholars who have announced high level research papers for shale. this study is a part of these stream. and this study not only analyzed strength anisotropy characteristic along with direction of testing(two-direction) by using point-load test(log-log method) but also compared uniaxial strength between the maximum saturated and dried condition. In this study, we also conducted slaking test. these results of slaking test show weathering characteristic of shales. also, we made the most of field data that obtained during slope stability project and we noticed that RQD measured in the field is much differ from drilled core RQD. In order to come close two different value or access to reality, we suggest new RQD method that artificially reduce RQD by separating core with light hand force.

• Structural Engineering and Mechanics
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• 제20권2호
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• pp.191-207
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• 2005

Time delay exists inevitably in active control, which may not only degrade the system performance but also render instability to the dynamic system. In this paper, a novel active controller is developed to solve the time delay problem in flexible structures. By using the independent modal space control method, the differential equation of the controlled mode with time delay is obtained from the time-delay system dynamics. Then it is discretized and changed into a first-order difference equation without any explicit time delay by augmenting the state variables. The modal controller is derived based on the augmented system using the discrete variable structure control method. The switching surface is determined by minimizing a discrete quadratic performance index. The modal coordinate is extracted from sensor measurements and the actuator control force is converted from the modal one. Since the time delay is explicitly included throughout the entire controller design without any approximation, the system performance and stability are guaranteed. Numerical simulations show that the proposed controller is feasible and effective in active vibration control of dynamic systems with time delay. If the time delay is not explicitly included in the controller design, instability may occur.

• Smart Structures and Systems
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• 제18권6호
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• pp.1125-1143
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• 2016

Forced vibration analysis of a simple supported viscoelastic nanobeam is studied based on modified couple stress theory (MCST). The nanobeam is excited by a transverse triangular force impulse modulated by a harmonic motion. The elastic medium is considered as Winkler-Pasternak elastic foundation.The damping effect is considered by using the Kelvin-Voigt viscoelastic model. The inclusion of an additional material parameter enables the new beam model to capture the size effect. The new non-classical beam model reduces to the classical beam model when the length scale parameter is set to zero. The considered problem is investigated within the Timoshenko beam theory by using finite element method. The effects of the transverse shear deformation and rotary inertia are included according to the Timoshenko beam theory. The obtained system of differential equations is reduced to a linear algebraic equation system and solved in the time domain by using Newmark average acceleration method. Numerical results are presented to investigate the influences the material length scale parameter, the parameter of the elastic medium and aspect ratio on the dynamic response of the nanobeam. Also, the difference between the classical beam theory (CBT) and modified couple stress theory is investigated for forced vibration responses of nanobeams.

• Structural Engineering and Mechanics
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• 제55권3호
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• pp.655-674
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• 2015

In this paper, a new and simplified method is presented in which the natural frequencies of the uniform and non-uniform beams are calculated through simple mathematical relationships. The various vibration problems such as: Rayleigh beam under variable axial force, axial vibration of a bar with and without end discrete spring, torsional vibration of a bar with an attached mass moment of inertia, flexural vibration of the beam with laterally distributed elastic springs and also flexural vibration of the beam with effects of viscose damping are investigated. The governing differential equations are first obtained and then; according to a harmonic vibration, are converted into single variable equations in terms of location. Through repetitive integrations, the governing equations are converted into weak form integral equations. The mode shape functions of the vibration are approximated using a power series. Substitution of the power series into the integral equations results in a system of linear algebraic equations. The natural frequencies are determined by calculation of a non-trivial solution for system of equations. The efficiency and convergence rate of the current approach are investigated through comparison of the numerical results obtained with those obtained from other published references and results of available finite element software.

• Steel and Composite Structures
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• 제29권3호
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• pp.319-332
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• 2018

This paper investigates the free vibration of geometrically imperfect functionally graded car-bon nanotube-reinforced composite (FG-CNTRC) beams that are integrated with two sur-face-bonded piezoelectric layers and subjected to a combined action of a uniform temperature rise, a constant actuator voltage and an in-plane force. The material properties of FG-CNTRCs are assumed to be temperature-dependent and vary continuously across the thick-ness. A generic imperfection function is employed to simulate various possible imperfections with different shapes and locations in the beam. The governing equations that account for the influence of initial geometric imperfection are derived based on the first-order shear deformation theory. The postbuckling configurations of FG-CNTRC hybrid beams are determined by the differential quadrature method combined with the modified Newton-Raphson technique, after which the fundamental frequencies of hybrid beams in the postbuckled state are obtained by a standard eigenvalue algorithm. The effects of CNT distribution pattern and volume fraction, geometric imperfection, thermo-electro-mechanical load, as well as boundary condition are examined in detail through parametric studies. The results show that the fundamental frequency of an imperfect beam is higher than that of its perfect counterpart. The influence of geometric imperfection tends to be much more pronounced around the critical buckling temperature.

• 환경위생공학
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• 제21권1호
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• pp.21-34
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• 2006

To investigate anti-HIV-1 activity of water soluble chitosans, sulfated chitosan derivatives were prepared in mild condition. Various sulfated chitosan derivatives (N-3,6-O-S-chitosan, N-desulfated 3,6-O-S-chitosan, 3,6-O-S-chitin, and 3,6-O-sulfated-N-(o-carboxybenzoyl) chitosan) were synthesized with sulfurtrioxidepyridene complex in pyridine solvent. Characterization of the sulfated chitosan derivatives was carried out by $^{13}C$ NMR and IR spectroscopies. To observe ionic reaction properties, pKas of the sulfated chitosan derivatives and chitosan of low molecular weight were estimated by potentiometric titration. The sulfated chitosan derivatives had high water solubility, pKas (pKa : 7.7) of N-3,6-O-S-chitosan and N-desulfated 3,6-O-S-chitosan were increased than pKa of water insoluble chitosan (pKa : 6.2), These results suggest the participation of electrostatic interaction of amino and sulfate groups on the sulfated chitosans. Anti-HIV-1 drugs, such as AZT, ddC, and ddI for anti-HIV activity had higher selective index compared with SCB-chitosan but N-3,6-O-S-chitosan has shown higher selective index compared with ddC and ddI as HIV drugs.. These results suggest that sulfated chitosan derivatives were expected as an anti-HIV drug with differential driving force mechanism against some nucleoside analogs drug in the future.