• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2007-2017
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• 2016

Background: Modifying lifestyle factors such as diet and exercise can reduce the risk of cancer. Psychological stress (PS) might be indirectly associated with cancer because it alters lifestyle factors. However, the relationship among these variables has not been fully investigated. Thus, we examined interactions between self-reported PS (SRPS) and habitual exercise on diet. Materials and Methods: In all, 5,587 men and 2,718 women were divided into "exerciser" and :non-exerciser" groips, based on whether they exercised reguarly, and classified into three SRPS levels: low, moderate and high. Diet was estimated using a validated food frequency questionnaire. Using a general linear model, food and nutrient consumption was estimated for each SRPS level in the 2 exercise groups, and the interactions between SRPS levels and exercise were calculated. Results: In women, the intake of pork and beef, low fat milk and yogurt, natto (fermented soybean), carrots and squash, other root vegetables, mushrooms, seaweeds, and wine along with the nutrients vegetable protein, soluble, insoluble and total dietary fiber, daidzein, genistein, carotene, retinol equivalents, vitamin B2, pantothenic acid, potassium, calcium, magnesium, phosphorus and iron demonstrated significant interaction with SRPS and habitual exercise (p for interaction <0.05). In men, raw and green leafy vegetable and fruit and vegetable juice significantly interacted with SRPS and habitual exercise (p for interaction <0.05). Conclusions: We suggest that certain foods and nutrients, which are thought to have a protective effect against cancer, interact with SRPS and habitual exercise, especially in women. This information is valuable for understanding and improving interventions for cancer prevention.

• 대한영양사협회학술지
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• 제19권4호
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• pp.373-388
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• 2013

The purpose of this study was to investigate the effects of a nutrition education and exercise on nutritional status in hemodialysis patients, with regard to quality of life (QoL), and fatigue. The subjects were divided into two groups : an educated (E) group (11 men and 9 women) and a non-educated (NE) group (7 men and 22 women). The educated group received a nutrition education and a regular exercise program for 3 months. Data on anthropometric indices and biochemical parameters were obtained from medical records. Dietary habits and nutrient intake were assessed through questionnaires and three-day food records. QoL (through the SF-36 questionnaire) and fatigue (measured by a visual analogue scale questionnaire) were assessed before and after the interventions. Dietary habit scores regarding food variety and fluid intake control significantly increased (P<0.05) after the nutrition education. Furthermore, the intake of total energy, carbohydrates, Fe, and vitamin A significantly increased (P<0.05). Vitamin C intake also significantly increased (P<0.01). Hb levels decreased whereas TG levels increased in the NE group. BUN levels decreased in the E group. After the nutrition education, QoL aspects, such as feelings of pain and general health, and the total score significantly increased (P<0.05) and the level of fatigue score decreased (P<0.01). The results of this study indicate that nutrition education and exercise for hemodialysis patients provides changes in dietary habit, daily nutrient intake, biochemical parameters, QoL, and the level of fatigue. Therefore, nutrition education and exercise help improve nutritional status and QoL.

• Nutrition Research and Practice
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• 제16권sup1호
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• pp.89-112
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• 2022

An accurate assessment of the recommended calcium (Ca) intake may contribute to reducing the risk of fractures and chronic diseases, ultimately improving quality of life. This review was performed to summarize key findings of Ca studies, investigate the effect of Ca intake on health outcomes, and determine the adequacy of evidence to revise the 2015 Dietary Reference Intakes for Koreans (KDRIs) for Ca in 2020. Databases were searched for intervention studies that assessed health outcomes by providing Ca in diets or as supplements. The framework of the systematic review comprised conducting literature searches, data extraction, quality assessment of the literature, and summarizing key findings relevant to set the Estimated Average Requirement (EAR) and Tolerable Upper Intake Level (UL) for Ca for the 2020 KDRI. The final search was performed in June 2019. A total of 13,309 studies were identified through databases and manual search. Sixtyfive studies were included in the final quality assessment and were summarized according to health indicators. As bone health was used as an indicator of the EAR for Ca, literature reports on bone health were further categorized by the life-cycle stage of the participants. This systematic review did not find new evidence that could be applied to the general Korean adult population, including postmenopausal women, for defining a new EAR for Ca in the 2020 KDRIs. Evidence in most of the reviewed literature was considered weak; however, some evidence was found that could improve the criteria on how the EAR for Ca was determined in children and adolescents. A review of the literature for the 2020 KDRIs for Ca did not find strong evidence in order to change the recommended values of the 2015 KDRIs. More clinical interventions are required among Koreans to strengthen the body of evidence to warrant the revision of the KDRIs.

• 한국식생활문화학회지
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• 제25권2호
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• pp.170-178
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• 2010

We conducted this study to determine the factors associated with childhood obesity. The subjects were 170 preschool children in Busan. Data were collected by using questionnaires which asked for information about socioeconomic status, parental perception of their child's weight status and dietary/physical activity behavior. BMI was calculated for each child and their classification was determined, according to their age and sex, as follows: "overweight" at or above the 85th percentile, "normal" for the 15th-85th percentile, and with a BMI below the 15th percentile the children were deemed as underweight. Classification according to BMI percentile showed that 23.5% ($18.25{\pm}1.33\;kg/m^2$) of the children were overweight, 62.9% ($15.51{\pm}0.76\;kg/m^2$) normal, and 13.5% ($13.23{\pm}2.86\;kg/m^2$) were underweight. Socioeconomic status, as represented by the parents' level of education, the occupation of the father and the household income, did not affect the results. However, mothers working outside the household was a factor that was more likely to affect the weight status (p<0.05). Among mothers whose children were overweight, 30% underestimated their children's weight status (believing them to be of normal weight when they were overweight), and 25% failed to recognize the necessity of weight control for their overweight children. While sedentary activity and total daily activity levels were not related to BMI, the level of physically active leisure activity was inversely correlated with BMI (p<0.05). Although there were no differences in total energy intake, dietary behavior was significantly related to weight status. Overweight children had poor eating tendancies: they eat faster (in less than 15 minutes), overeat, and eat late at night. Based on our findings where hereby recommended the following interventions to help limit weight problems in Korean pre-schoolers: early promotion of active leisure behavior and healthy eating habits, along with attempting to correct parental misperception of healthy weight status for children.

• Journal of Nutrition and Health
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• 제57권1호
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• pp.65-74
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• 2024

Purpose: Sodium is essentially required for homeostasis and physiological functions, but excessive sodium consumption increases the risk of obesity and other chronic disorders. Korean studies on the sodium-obesity relationship are limited, and thus, this study was undertaken to determine the nature of the relationship between sodium intake and obesity in Korean adults. Methods: Forty-two participants were divided into 2 groups according to body mass index (BMI, non-obese BMI < 25 kg/m², obese BMI ≥ 25 kg/m²). Dietary intakes and eating habits were analyzed using 3-day food records and a food frequency questionnaire. Anthropometric data were obtained from bioimpedance results, and fasting glucose and lipid levels were measured. Results: Mean weight, BMI, waist and hip circumferences, and body fat mass were greater in the obese group than in the non-obese group for men and women. Skeletal muscle mass and body fat mass were higher in obese women than in non-obese women. Biochemical data were no different in these two subgroups except triglycerides (TGs), which were higher in obese women. Nutrient intakes were not significantly different in obese and non-obese groups. However, obese men consumed excessive sodium, while obese women consumed slightly more than non-obese women. Obese men preferred salty foods and tended to overeat. Positive correlations were found between sodium intake and weight in men and percent body fat mass (PBFM) in women. Correlation analysis (adjusted for energy intake) of the relation between sodium intake and obesity-related factors showed sodium intake was positively correlated with PBFM and TG in women. Conclusion: This anthropometric and biochemical data analysis emphasizes the need for awareness and interventions to mitigate the health risks of elevated sodium consumption. Our findings should aid future studies on the relationship between sodium and obesity and contribute to preventing and managing this metabolic condition.

• Nutrition Research and Practice
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• 제9권2호
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• pp.165-173
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• 2015

BACKGROUND/OBJECTIVES: This study addressed the question whether the composition of supposedly 'healthy' or 'unhealthy' dietary regimes has a calorie-independent short-term effect on biomarkers of metabolic stress and vascular risk in healthy individuals. SUBJECTS/METHODS: Healthy male volunteers (age $29.5{\pm}5.9years$, n = 39) were given a standardized baseline diet for two weeks before randomization into three groups of different dietary regimes: fast food, Mediterranean and German cooking style. Importantly, the amount of calories consumed per day was identical in all three groups. Blood samples were analyzed for biomarkers of cardiovascular risk and metabolic stress after two weeks of the baseline diet and after two weeks of the assigned dietary regime. RESULTS: No dietary intervention affected the metabolic or cardiovascular risk profile when compared in-between groups or compared to baseline. Subjects applied to the Mediterranean diet showed a statistically significant increase of uric acid compared to baseline and compared to the German diet group. Plasma concentrations of urea were significantly higher in both the fast food group and the Mediterranean group, when compared to baseline and compared to the German diet group. No significant differences were detected for the levels of vitamins, trace elements or metabolic stress markers (8-hydroxy-2-deoxyguanosine, malondialdehyde and methylglyoxal, a potent glycating agent). Established parameters of vascular risk (e.g. LDL-cholesterol, lipoprotein(a), homocysteine) were not significantly changed in-between groups or compared to baseline during the intervention period. CONCLUSIONS: The calorie-controlled dietary intervention caused neither protective nor harmful short-term effects regarding established biomarkers of vascular or metabolic risk. When avoiding the noxious effects of overfeeding, healthy individuals can possess the metabolic capacity to compensate for a potentially disadvantageous composition of a certain diet.

• 대한지역사회영양학회지
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• 제24권6호
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• pp.465-475
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• 2019

Objectives: This study investigated dietary and lifestyle factors associated with the weight status among Korean adolescents in multicultural families. Methods: This cross-sectional study analyzed 1,751 multicultural families' adolescents who participated in the 2017-2018 Korea Youth Risk Behavior Surveys. Information on dietary and lifestyle factors was self-reported using a web-based questionnaire and this information included breakfast and foods consumption, perceived health status, alcohol drinking, smoking, physical activity, and weight control efforts. Body mass index (BMI) was calculated based on the self-reported height and body weight (kg/㎡). Weight status was assessed according to the 2017 Korean National Growth Chart: underweight (weight-for-age <5^th percentiles), overweight (85^th≤ BMI-for-age <95^th percentiles), and obese (BMI-for-age ≥95^th percentiles). Multiple logistic regression analysis was performed to examine the dietary and lifestyle factors associated with weight status after adjustment for covariates. Results: Among Korean adolescents from multicultural families, the prevalence of overweight/obesity was 20.9%, whereas about 7% of adolescents were underweight. The weight status did not show differences according to gender, school level, area of residence, and household income. Compared to adolescents who did not have breakfast during the previous week, those who had breakfast 3-4 days/week and ≥5 days/week had a 42% (p=0.021) and a 37% (p=0.009) lower prevalence of overweight/obesity, respectively. The adolescents who frequently consumed carbonated soft drinks (≥5 times/week) showed an odds ratio (OR) of 1.69 (95% CI=1.01-2.83) for overweight/obesity relative to those adolescents who did not consume carbonated soft drinks. The OR of being underweight for adolescents who ate fast food ≥3 times/week was 1.97 (95% CI=1.04-3.71) compared to those adolescents who had not eaten fast food during the previous week. Conclusions: Dietary and lifestyle factors were associated with overweight/obesity as well as underweight among Korean adolescents in multicultural families. Our findings could be used to design and provide nutrition interventions for this specific population.

• 한국식품과학회지
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• 제53권2호
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• pp.213-217
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• 2021

Benign prostate hyperplasia (BPH) is one of the most common elderly disease, and because of prolonged incubation period and many side effects of medication or surgical interventions, the use of dietary phytochemicals is considered as an effective measure for prevention of BPH. The purpose of this study is to investigate the mechanism of inhibition effect for BPH by flavonoids such as baicalein and kaempferol. BPH cells were collected through biopsy from patients with PSA of 4 or higher, followed by primary culture. In vitro experiments were conducted to evaluate mitochondrial respiration, intracellular reactive oxygen species (ROS) level and expression of inflammatory markers, genes, and anti-oxidants. In conclusion, baicalein and kaempferol have been demonstrated to inhibit BPH through lowering ROS, thereby reducing inflammation triggers, and reduced inflammation. This study is expected to be helpful in the development of flavonoids that have a clinical effect on suppressing BPH.

• Animal Bioscience
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• 제36권2_spc호
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• pp.364-373
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• 2023

The gastrointestinal (GI) tract of ruminants contains diverse microbes that ferment various feeds ingested by animals to produce various fermentation products, such as volatile fatty acids. Fermentation products can affect animal performance, health, and well-being. Within the GI microbes, the ruminal microbes are highly diverse, greatly contribute to fermentation, and are the most important in ruminant nutrition. Although traditional cultivation methods provided knowledge of the metabolism of GI microbes, most of the GI microbes could not be cultured on standard culture media. By contrast, amplicon sequencing of 16S rRNA genes can be used to detect unculturable microbes. Using this approach, ruminant nutritionists and microbiologists have conducted a plethora of nutritional studies, many including dietary interventions, to improve fermentation efficiency and nutrient utilization, which has greatly expanded knowledge of the GI microbiota. This review addresses the GI content sampling method, 16S rRNA gene amplicon sequencing, and bioinformatics analysis and then discusses recent studies on the various factors, such as diet, breed, gender, animal performance, and heat stress, that influence the GI microbiota and thereby ruminant nutrition.

• 대한지역사회영양학회지
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• 제23권4호
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• pp.318-332
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• 2018

본 연구에서는 12주 동안 성인 여성 중 체지방률 40% 이상 또는 BMI 30 이상인 여성을 대상으로 37차시의 비만관리 프로그램일환으로 영양교육과 운동중재를 병행 실시하여 대상자의 식습관 및 운동 습관 조사, 신체성분과 식이섭취와 생화학적 지표에 미치는 효과를 살펴보고자 하였다. 1. 조사대상자의 평균 연령은 44.8세였으며 참여자의 55%가 폐경이었다. 2. 체중조절 관심도 변화에서 체중 조절 방법은 식사조절과 운동이 프로그램 참여 전 34.4%에서 프로그램 후 37.5%로 증가하였다(p<0.01). 3. 신체활동 변화에서 중등도 신체활동을 10분 이상 한날은 프로그램 참여 전 3.20일에서 프로그램 후 4.25일로 증가하고, 스트레칭 등 유연성 운동을 한 날은 프로그램 참여 전 2.60일에서 프로그램 참여 후 3.85일로 유의적으로 증가하였다(p<0.01). 4. 바른 식습관 점수 변화는 프로그램 참여 전 4.15점에서 프로그램 참여 후 7.10점으로 유의적(p<0.001)으로 증가하였다. 5. 에너지 및 다량 영양소 섭취는 프로그램 전후간 차이는 없었으나 식이섬유(p<0.01), 철, 칼륨, 비타민A, 비타민 $B_6$, 나이아신의 섭취는 프로그램 참여 전에 비해 프로그램 참여 후에 유의적으로 증가하였다(p<0.05). 6. 혈압과 혈액 생화학적 특성 지표인 TC, 공복혈당 및 TG는 프로그램 참여 전후 간 유의적인 차이는 없었다. 7. 영양교육과 운동 프로그램 종료 후 체중, 체지방률, 복부둘레 및 내방지방 수치는 유의적으로 감소하였으며, 근육양과 신체발달 점수는 유의적으로 증가하였다(p<0.001). 이상의 결과를 볼 때, 중등도 비만여성에서 12주간 영양교육과 운동 중재 프로그램 실시는 식사의 질을 향상시키고 바림직한 식습관의 변화를 유도하였으며 비만도는 감소하면서 근육양이 증가하여 요요현상이 없이 비만관리 프로그램 교육 내용이 긍정적인 영향을 미쳤으며, 향후 장기적인 비만의 지속관리와 체계적인 연구가 계속되어야 할 것으로 사료된다.