• Journal of the Korean Society of Food Science and Nutrition
• /
• v.23 no.5
• /
• pp.718-724
• /
• 1994

The study was conducted to investigated the effect of dietary levels of zinc (Zn) on lipid metabolism in cadmium (Cd) treated rats. Sixty male Sprague-Dawley rats weighing about 110$\pm$10g were divided into 6 groups. The Zn levels were low (0ppm), control (30 ppm) and Cd-treated groups were administrated with Cd chloride (5.0mg/kg of body weight) by oral intubation at the same time once a week. Serum total lipid, triglyceride , total cholesterol and DHL-cholesterol contents decreased significantly in low Zn group. In serum dietary high Zn group, it decreased significantly in the content of triglyceride but total cholesterol and HDL- cholesterol revealed increase slightly . Total lipid and triglyceride contents increased by Cd oral intubation, but triblyceride content of control group decreased significantly in Cd-treated groups. HDL-cholesterol content also decreased by Cd oral intubationl. Cd-treatment increased total cholesterol content in low Zn group. Liver triglyceride content increased as dietary Zn level became more increasing and total lipid was not influenced by dietary Zn levels. Liver cholesterol content was higher in low and high Zn groups than that of control group. Liver phospholipid content decreased in low Zn group . Oral intubation of Cd increased in the contents of triglyceride and total lipid. The content of liver Zn was not influenced by the dietary low Zn but that of serum showed a remarkable increased . Oral Cd intubation increased the Cd contents of liver and serum.

• Journal of Nutrition and Health
• /
• v.24 no.2
• /
• pp.87-96
• /
• 1991

This study was undertaken to investigate the effect of the levels of dietary Zn and alcohol consumption on lipid metabolism in Sprague-Dawley male rats weighing 80 to 90g for eight weeks. Ninety rats were divided into nine groups according to Zn levels and alcohol consumption such as no alcohol group[low Zn diet group(<1ppm. LZ) control Zn diet group(30ppm. CZ) high Zn diet group(60ppm, HZ)] 10% alcohol consumption group[the same Zn levels as no alcohol group LZLA, CZLA, HZLA] 20% alcohol consumption group[the same Zn levels as no alcohol group, LZHA, CZHA, HZHA] The results obtained were summarized as following : 1) In the serum total cholesterol increased with increasing dietary Zn levels but decreased with alcohol consumption. HDL-cholesterol decreased with alcohol consumption. Triglyce-ride in alcohol group was higher than no alcohol group. In alcohol group triglyceride increased with decreasing dietary Zn levels. 2) In the liver total lipid in alcohol group was higher than no alcohol group HA group showed a significant increase. Triglyceride increased with alcohol consumption. 3) In the serum and liver Zn content increased with increasing dietary Zn levels but decreased with alcohol consumption.

• Journal of the Korean Society of Food Science and Nutrition
• /
• v.23 no.1
• /
• pp.1-6
• /
• 1994

The present study was conducted to evaluate the effect of dietary levels of vitamin A on the lipid composition in rats fed Zn-deficient diets. Fifty male Sprague-Dawley rats were fed 5 experimental diets for 7 weeks. Rats were fed Zn-and vitamin A-deficient diet or the same diets supplemented with various levels of vitamin. A liver total lipid, cholesterol and triglycerides contents tended to decrease in Zn-deficient rats, but the supplementation of excess vitamin A enhanced those contents. Plasma cholesterol content was significantly higher in feeding Zn-deficient and excess vitamin A diet. Plasma triglyceride and phospolipid contents were higher in Zn-deficient groups, but not influenced by dietary levels of vitamin. A . Plasma HDL-cholesterol content was not changed by Zn-deficient diets. Plasma alkaline phosphatase activity was significantly reduced in Zn-deficient groups. Zinc contents of plasma and liver were influenced by the dietary level of zinc, but not changed by supplementation of vitamin A.

• Journal of Environmental Health Sciences
• /
• v.33 no.5
• /
• pp.397-402
• /
• 2007

The present study was initiated to examine the measures of dietary intake of Fe, Cu and Zn. The food duplicate samples were collected in Busan and its neighboring area, from the 69 middle-aged women (healthy non-smoking, mostly house wives), who provided informed consent. The samples were wet ashed by being heated in the presence of mineral acids, and Fe, Cu, Zn in the wet-ashed samples were analyzed by inductively coupled plasma - atomic emission spectrometry(ICP-AES). Dietary intake of Fe, Cu and Zn were 10.4 mg/day in Fe, 1.2 mg/day in Cu, 7.4 mg/day as arithmetic mean. The values for dietary Fe and Zn were lower, and the values for dietary Cu were higher than the recommended daily intake from Korean Nutrition Society. Further studies of Korean foods are needed to clarify the representative values for daily dietary Fe, Cu and Zn intake in the Korean population.

• Journal of the Korean Home Economics Association
• /
• v.28 no.3
• /
• pp.25-32
• /
• 1990

This study was carried out to observe the effects of dietary sources of vitamin A and Zn levels on Zn and vitamin A distribution in rats fed excess vitamin A diet. In this study, 40 weanling male rats of the Sprague-Dawley strain, weighing 40-50g, were chosen and divided into for groups by dietary Zn levels and the sources of vitamin A. The two levels of dietary Zn were supplied: adequate Zn(30mg Zn/Kg diet), low Zn(3mg Zn/Kg diet). Excess vitamin A level was 100 times of RDA, retional and $\beta$-carotene were used as the sources of vitamin A. Vitamin A concentration of plasma and liver were significantly higher in rats fed retional than in rats fed $\beta$-carotene (p<0.05), but these were not affected by dietary Zn levels. Vitamin A accumulationin the liver appeared to be servere in rats fed retinol and low Zn diet. Zn levels of plasma and liver were not affected by the sources of vitamin A whereas Zn levels of kidney were slightly lower in retinol group, and Zn levels of tests were found to be significantly lower in rats fed retinol and low Zn diet. Fragility of erythrocytes in hypotonic saline soultion was greater in low Zn groups, whereas the lower fragility was found in adequate Zn groups in feeding excess vitamin A diet. Thus, these results suggest that an adequate Zn intake is preferable when excess vitamin A is taken, and $\beta$-carotene intake is more beneficial than retinol in order to diminish toxic effects of vitamin A.

• Korean Journal of Agricultural Science
• /
• v.51 no.1
• /
• pp.53-61
• /
• 2024

A total of 180 21-day-old weaning pigs ([Yorkshire × Landrace] × Duroc) with an initial body weight of 6.44 ± 0.01 kg were randomly assigned to 9 treatments for evaluating the effects of replacing dietary inorganic copper (Cu) and zinc (Zn) with glycine (Gly) or methionine (Met)-chelated Cu and Zn on growth performance and nutrient digestibility. The experimental period was 35 days. There were four replicated pens per treatment, with five pigs (three males and two females) per pen. Dietary treatments consisted of a basal diet (CON), in which the sources of Cu and Zn were in inorganic form. The inorganic Cu and Zn in the basal diet were replaced by glycine-chelated (GC) and methionine-chelated (MC) Cu and Zn by 30, 50, 70, or 100% to form the GC1, GC2, GC3, GC4, or MC1, MC2, MC3, MC4 groups. The 100% replacement of dietary inorganic Cu and Zn with GC or MC increased (p < 0.05) average daily gain, average daily feed intake, and gain-to-feed ratio. The complete replacement of dietary inorganic Cu and Zn with GC or MC led to enhanced (p < 0.05) digestibility of dry matter, nitrogen, Cu and Zn. Thus, the replacement of inorganic Cu and Zn with GC or MC can improve the growth efficiency and nutrient utilization of weaning pigs.

• Journal of Nutrition and Health
• /
• v.15 no.4
• /
• pp.258-267
• /
• 1982

This study was performed to investigate the effect of different levels of protein and iron in the diet upon Fe, Cu and Zn metabolism in rat during four weeks of growing period. Forty-five male weanling rats of Sprague-Dawley strain weighing $68.5{\pm}1.1g$ were divided into 9 groups and each group was given with one of the 9 different kinds of diets for four weeks. The three dietary protein levels used were 5, 20 and 40% and Fe levels 0, 35, and 350 ppms. The results obtained were summarized as following ; 1) Food intake and body weight gain in 20%(SP) and 40%(HP) dietary protein groups tended to be significantly higher than 5%(LP) protein groups. Protein efficiency ratio (PER) was higher in LP groups than in HP and SP groups. With dietary Fe levels, there were no significant differences among groups in food intake, body weight gain, and PER. 2) In LP groups, the Fe concentrations in liver, kidney, and hind limb muscle were higher than in SP and HP groups. Regarding with dietary protein levels, the liver Cu concentrations in LP groups were slightly higher, but the liver Zn concentrations were lower in LP groups. The Fe concentrations in liver and kidney tended to decrease with decrease in dietary Fe levels, but Cu and Zn concentrations showed no consistent tendency with dietary Fe levels. 3) The Fe, Cu and Zn concentrations in serum were not different from dietary treatments except that the serum Fe concentrations increased slightly in LP groups. 4) The Fe and Cu concentrations in urine tended to be higher in HP groups. Fecal Cu and Zn concentrations showed no significant differences in dietary protein or Fe levels, but the Fe concentrations tended to increase with increase in dietary Fe levels.

• Asian-Australasian Journal of Animal Sciences
• /
• v.21 no.9
• /
• pp.1348-1354
• /
• 2008

Two inorganic (zinc sulfate and zinc oxide) and three organic (zinc acetate, zinc-methionine, and zinc-lysine) zinc sources were evaluated for their effects on the performance and carcass characteristics of broiler chicks. The birds were randomly assigned to one control (non-supplemented) and 15 treatment (supplemented) groups consisting of four replicates of 10 chicks each in a $5{\times}3$ factorial arrangement of treatments (five zinc sources and three supplemental zinc levels). Birds were kept in floor pens in a temperature-controlled room from 1 to 42 d of age and fed a non-supplemented basal diet (control) or the basal diet supplemented with 40, 80 or 120 mg/kg of Zn as mentioned sources. Dietary zinc source had considerable effect on feed intake in all experimental periods. Increasing Zn level from 80 to 120 mg/kg decreased the average feed intake in the growth stage (p<0.01) and also in the entire experimental period (p<0.001). Similarly, the average daily gain during the entire trial period was affected by the type of Zn source (p<0.001) and supplemental level (p<0.01). One degree of freedom contrast comparisons showed that the inclusion of organic zinc sources into the diets caused significant increases in feed intake and body gain when compared with inorganic counterparts. Except in wk 1, dietary supplementation with organic sources improved (p<0.05) feed conversion ratio; FCR values were not affected by dietary Zn source or supplementation level. Breast meat yield increased with supplemental levels of organic Zn sources; however, other carcass parameters were not affected by dietary Zn source. On the other hand, organic versus inorganic zinc supplementation caused a significant increase in liver, breast and carcass weight percentages. The present findings suggest that supplemental levels of organic Zn compounds had beneficial effects on broiler performance, and Zn requirements can be reduced using these feed supplements in poultry rations.

• Proceedings of the Korea Society of Poultry Science Conference
• /
• 2001.11a
• /
• pp.66-68
• /
• 2001

An experiment was conducted investigate the of supplemental Cu and Zn methionine chelates on the performance, nutrient digestibility, serum IgG level, gizzard erosion, and Cu and Zn contents in the liver and excretion of broiler chickens. One thousand hatched broiler chickens (Ross) of one day old were assigned to 4 treatments:control(T1), 100ppm of copper in the from of Cu-methionine chelate(Cu-Met, T2), 100ppm of zinc in the from of Zn-methionine chelate(Zn-Met, T3) and 100ppm of copper plus 100ppm of zinc in the from of methionine chelate(Cu-Zn-Met, T4). Each treatment had four replications of 50 bird each. Weight gain of chicks fed chelated products were significantly higher than that of chicks fed control(P＜0.05).Combination of Cu and Zn chelates(Cu-Zn-Met) tended to show the best growth rate and feed conversion ratio. Nutrient digestibilities were not affected by dietary treatments. Serum IgG level of chicks fed Cu-Zn-Met was significantly higher than that of chicks fed control(P＜0.05). Gizzard erosion index was not significantly different among treatments. Contents of Cu and Zn in liver were not significantly affected by dietary treatments, whereas excretions of these minerals were significantly affected by dietary treatments.

• Korean Journal of Agricultural Science
• /
• v.49 no.1
• /
• pp.163-170
• /
• 2022

This study investigates the effects of the dietary inclusion of zinc oxide (ZnO) on the growth performance, apparent total digestibility, and the fecal scores of growing pigs fed a corn-wheat-based diet. In total, 84 crossbred (Landrace × Yorkshire × Duroc) growing pigs with an initial body weight of (20.86 ± 0.64 kg) (4 pigs·pen^-1; 2 gilts and 2 barrows; 7 replications·treatment^-1) were randomly assigned to three treatment groups based on body weight (BW) and sex in a three-week trial. The dietary treatments were as follows: TRT1 (CON [basal diet]), TRT2 (CON + 0.07% ZnO), and TRT3 (CON + 1% ZnO). Dietary ZnO supplementation significantly (p < 0.05) improved body weight gain (BWG) of growing pigs at weeks 2 and 3 compared to the control diet. In addition, dietary ZnO supplementation significantly (p < 0.05) increased the average daily gain (ADG) and average daily feed intake (ADFI) at weeks 2, 3, and overall. However, the feed conversion ratio (FCR) remained unaffected throughout the trial. Regarding the total tract nutrient digestibility of nitrogen, dry matter was significantly improved with an increased level of ZnO supplementation. In addition, dietary supplementation of ZnO significantly reduced fecal scores in grower pigs at the initial period compared to the control diet. In summary, dietary inclusion of zinc oxide via supplementation improved growth performance, and total tract digestibility and reduced the fecal scores of growing pigs.