• 말소리와 음성과학
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• 제8권2호
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• pp.17-22
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• 2016

This paper devises a model to diagnose physical fatigue using speech features. This paper presents a machine learning method through an SVM algorithm using the various feature parameters. The parameters used include the significant speech parameters, questionnaire responses, and bio-signal parameters obtained before and after the experiment imposing the fatigue. The results showed that performance rates of 95%, 100%, and 90%, respectively, were observed from the proposed model using three types of the parameters relevant to the fatigue. These results suggest that the method proposed in this study can be used as the physical fatigue diagnostic model, and that fatigue can be easily diagnosed by speech technology.

• Communications for Statistical Applications and Methods
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• 제9권2호
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• pp.521-531
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• 2002

Various diagnostic techniques for identifying influential observations are mostly based on the deletion of a single observation. While such techniques can satisfactorily identify influential observations in many cases, they will not always be successful because of some mask effect. It is necessary, therefore, to develop techniques that examine the potentially influential effects of a subset of observations. The partial regression plots can be used to examine an influential observation for a single parameter in multiple linear regression. However, it is often desirable to detect influential observations for a subset of regression parameters when interest centers on a selected subset of independent variables. Thus, we propose a diagnostic measure which deals with detecting influential observations on a subset of regression parameters. In this paper, we propose a measure M, which can be effectively used for the detection of influential observations on a subset of regression parameters in multiple linear regression. An illustrated example is given to show how we can use the new measure M to identify influential observations on a subset of regression parameters.

• 전기전자학회논문지
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• 제12권2호
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• pp.87-94
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• 2008

골반저근은 골반기관을 지지하여 요자제를 유지하는 여성의 주요 하부조직으로 수축압력을 평가함으로써 복압성 요실금의 정도를 진단할 수 있다. 본 연구에서는 생체신호 측정 시스템을 개발하여 골반저근의 수축압력을 측정하였으며, 데이터 분석을 통하여 진단 파라메터를 추출하였다. 진단 파라메터의 통계적 분석을 수행하여 특성이 유사한 피험자를 다섯 개의 군집으로 분류하였으며, 군집으로 분류된 데이터가 중첩되지 않도록 복압성요실금 진단 알고리즘을 구현하였다. 임상시험 결과 진단 알고리즘의 정확성이 약 78.9%로 나타났으며 그 유용성이 확인되었다.

• Imaging Science in Dentistry
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• 제44권1호
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• pp.31-35
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• 2014

Purpose: This study was performed to investigate the effect of image enhancement of periapical radiographs according to the diagnostic task. Materials and Methods: Eighty digital intraoral radiographs were obtained from patients and classified into four groups according to the diagnostic tasks of dental caries, periodontal diseases, periapical lesions, and endodontic files. All images were enhanced differently by using five processing techniques. Three radiologists blindly compared the subjective image quality of the original images and the processed images using a 5-point scale. Results: There were significant differences between the image quality of the processed images and that of the original images (P< 0.01) in all the diagnostic task groups. Processing techniques showed significantly different efficacy according to the diagnostic task (P< 0.01). Conclusion: Image enhancement affects the image quality differently depending on the diagnostic task. And the use of optimal parameters is important for each diagnostic task.

• 대한예방의학회:학술대회논문집
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• 대한예방의학회 1994년도 교수 연수회(역학)
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• pp.154-157
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• 1994

The evaluation of diagnostic tests attempts to obtain one or more statistical parameters which can indicate the intrinsic diagnostic utility of a test. Sensitivity. specificity and predictive value are not appropriate for this use. The likelihood ratio has been proposed as a useful measure when using a test to diagnose one of two disease states (e.g. disease present or absent). In this paper, we generalize the likelihood ratio concept to a situation in which the goal is to diagnose one of several non-overlapping disease states. A formula is derived to determine the post-test probability of a specific disease state. The post-test odds are shown to be related to the pre-test odds of a disease and to the usual likelihood ratios derived from considering the diagnosis between the target diagnosis and each alternate in turn. Hence, likelihood ratios derived from comparing pairs of diseases can be used to determine test utility in a multiple disease diagnostic situation.

• Asian Pacific Journal of Cancer Prevention
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• 제17권9호
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• pp.4433-4437
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• 2016

Background: Gastric cancer (GC) is the fifth most common cancer worldwide. Since development is usually asymptomatic, it is generally diagnosed at an advanced stage. The value of screening in patients with nonspecific symptoms for GC is controversial. Aim: The study aimed to evaluate whether hematological parameters (platelet count (PC), mean platelet volume (MPV), MPV/PC ratio, red blood cell distribution width (RDW), neutrophil to lymphocyte ratio (NLR), and platelet to lymphocyte ratio (PLR)) are useful markers to differentiate between gastric cancer patients and healthy individuals. Materials and Methods: Sixty-one patients with gastric cancer and sixty-one healthy individuals were enrolled to the survey and retrospective analysis of selected blood parameters were performed. Results: The mean values of PC, MPV, RDW, NLR, and PLR were significantly higher in GC patients compared to the control group. No statistical differences were observed in MPV/PC ratios. Likewise, no significant statistical differences were revealed in values of blood parameters among TNM stage groups. The RDW showed the highest diagnostic specificity and sensitivity. Conclusions: Hematological parameters: PC, MPV, RDW, NLR, PLR have diagnostic power and can discriminate patients with gastric cancer from patients without cancer. Blood parameters compared with clinical symptoms might alert physicians and patients and lead to performancce of upper gastrointestinal endoscopy, the gold standard in gastric cancer screening and therebly increase the early detection of cancer.

• Korean Journal of Radiology
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• 제1권2호
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• pp.91-97
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• 2000

Objective: To determine whether the time-intensity curves acquired by test and main dose contrast injections for MR angiography are similar. Materials and Methods: In 11 patients, repeated contrast-enhanced 2D-turbo-FLASH scans with 1-sec interval were obtained. Both test and main dose timeintensity curves were acquired from the abdominal aorta, and the parameters of time-intensity curves for the test and main boluses were compared. The parameters used were arterial and venous enhancement times, arterial peak enhancement time, arteriovenous circulation time, enhancement duration and enhancement expansion ratio. Results: Between the main and test boluses, arterial and venous enhancement times and arteriovenous circulation time showed statistically significant correlation (p < 0.01), with correlation coefficients of 0.95, 0.92 and 0.98 respectively. Although the enhancement duration was definitely greater than infusion time, reasonable measurement of the end enhancement point in the main bolus was impossible. Conclusion: Only arterial and venous enhancement times and arteriovenous circulation time of the main bolus could be predicted from the test-bolus results. The use of these reliable parameters would lead to improvements in the scan timing method for MR angiography.

• Asian Pacific Journal of Cancer Prevention
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• 제15권4호
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• pp.1751-1755
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• 2014

Background: In this study prognostic correlations of histopathologic parameters and the Ki-67 proliferation index and as well as the diagnostic value of immunohistochemical markers in pheochromocytomas were evaluated. Materials and Methods: A total of 22 patients diagnosed with a pheochromocytoma between 2000-2010 in Izmir Katip Celebi University Ataturk Training and Research Hospital were included. Diagnostic value of the PASS scoring system, and prognostic correlations of histopathologic parameters and Ki-67 proliferation index were investigated. SPSS for Windows 17.0 software was used for statistical analysis. Results: There was no statistically significant correlation between recurrence and clinicopathologic parameters or the PASS score (PASS>4). In addition, there were no statistically significant correlations between PASS score and clinicopathologic parameters, such as diameter (5 cm), weight (>100g), gender (female/male ratio) and age (25-45/45-55/>55). Besides, there were no significant correlation between diameter and clinicopathological parameters and also recurrence. However, there was a statistically significant correlation between Ki-67 proliferation index and capsule invasion (p=0.047). Conclusions: Some but not most of the findings in our study were concordant with the literature. To clarify relationships, investigations with standard scoring systems which are not affected by subjective factors and feature appropriate histopathological criteria should be made on larger study groups.

• 한방재활의학과학회지
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• 제19권3호
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• pp.91-100
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• 2009

Objectives : The purpose of this study was to find the characteristics of Sasang Constitution, Soeumin, Soyangin and Taeumin, Using Regular Medical Inspection. Methods : Subjects of our study were 325 cases who took regular medical inspection. We collected the data of body composition analysis, 7-zone-diagnostic system, blood analysis, and analyzed by Sasang Constitution, Soeumin, Soyangin and Taeumin. Results and Conclusions : 1. In body composition analysis, Taeumin was significantly higher than Soeumin and Soyangin about soft lean mass, body fat mass, waist-hip ratio, body water index, body mass index and basal metabolic rate. In blood analysis, Taeumin was significantly highest about total protein, albumin, GPT, hemoglobin, WBC, triglyceride. In 7-zone-diagnostic system, Taeumin had the highest level at Zone 1, 2. 2. Taeumin had more significant differences than other Sasang constitutions about the parameters of regular medical inspection. 3. Body composition analysis had the most parameters that showed differences among the constitutions, followed by blood analysis and 7-zone-diagnostic system.

• 대한핵의학회지
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• 제37권4호
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• pp.207-218
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• 2003

Myocardial perfusion imaging has been increasingly used to provide prognostic data and guidance on the choice of appropriate management of patients with known or suspected coronary artery disease. The electrocardiogram gated myocardial SPECT program is corning into wide use with an advent of $^{99m}Tc-labeled$ tracers and an improvement of SPECT machines. The gated technique permits measurement of important cardiac prognostic indicators without any further discomforts or radiation burden in patients underwent standard myocardial perfusion SPECT. In addition, gated study significantly improves diagnostic yield by reducing the number of borderline interpretations and could find myocardial stunning and viable myocardium. Gated single photon emission computed tomography (SPECT) imaging allows the automated calculation of end-diastolic volume, end-systolic volume, ejection fraction, myocardial mass and the assessment of regional wall motion and thickening, and it have dramatically improved assessment of coronary artery disease in routine nuclear practice. This allows the simultaneous assessment of both perfusion and function within the same acquisition, and serves as a cost-effective technique for providing more diagnostic data with fewer diagnostic tests. Because the diagnostic and prognostic power derived from knowledge of left ventricular function can be added to that provided by assessing myocardial perfusion, gated SPECT imaging has rapidly gained widespread acceptance and is now used on a routine clinical basis in a growing number of laboratories, including South Korea. The gated SPECT technique for measurement of left ventricular parameters has been validated against a variety of well established techniques. In this work, overview of gated myocardial perfusion SPECT focus on functional parameters is presented.