• Title/Summary/Keyword: diagnostic model

Search Result 843, Processing Time 0.032 seconds

Accuracy of Digital Breast Tomosynthesis for Detecting Breast Cancer in the Diagnostic Setting: A Systematic Review and Meta-Analysis

  • Min Jung Ko;Dong A Park;Sung Hyun Kim;Eun Sook Ko;Kyung Hwan Shin;Woosung Lim;Beom Seok Kwak;Jung Min Chang
    • Korean Journal of Radiology
    • /
    • v.22 no.8
    • /
    • pp.1240-1252
    • /
    • 2021
  • Objective: To compare the accuracy for detecting breast cancer in the diagnostic setting between the use of digital breast tomosynthesis (DBT), defined as DBT alone or combined DBT and digital mammography (DM), and the use of DM alone through a systematic review and meta-analysis. Materials and Methods: Ovid-MEDLINE, Ovid-Embase, Cochrane Library and five Korean local databases were searched for articles published until March 25, 2020. We selected studies that reported diagnostic accuracy in women who were recalled after screening or symptomatic. Study quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies-2 tool. A bivariate random effects model was used to estimate pooled sensitivity and specificity. We compared the diagnostic accuracy between DBT and DM alone using meta-regression and subgroup analyses by modality of intervention, country, existence of calcifications, breast density, Breast Imaging Reporting and Data System category threshold, study design, protocol for participant sampling, sample size, reason for diagnostic examination, and number of readers who interpreted the studies. Results: Twenty studies (n = 44513) that compared DBT and DM alone were included. The pooled sensitivity and specificity were 0.90 (95% confidence interval [CI] 0.86-0.93) and 0.90 (95% CI 0.84-0.94), respectively, for DBT, which were higher than 0.76 (95% CI 0.68-0.83) and 0.83 (95% CI 0.73-0.89), respectively, for DM alone (p < 0.001). The area under the summary receiver operating characteristics curve was 0.95 (95% CI 0.93-0.97) for DBT and 0.86 (95% CI 0.82-0.88) for DM alone. The higher sensitivity and specificity of DBT than DM alone were consistently noted in most subgroup and meta-regression analyses. Conclusion: Use of DBT was more accurate than DM alone for the diagnosis of breast cancer. Women with clinical symptoms or abnormal screening findings could be more effectively evaluated for breast cancer using DBT, which has a superior diagnostic performance compared to DM alone.

A Study on Applications of Regression Diagnostic Method to Technometrics, and the Statistical Quality Control

  • Kim, Soon-Kwi
    • Journal of Korean Society for Quality Management
    • /
    • v.21 no.1
    • /
    • pp.55-64
    • /
    • 1993
  • This article is concerned with procedures for detecting one or more outliers or influential observations in a linear regression model. A test procedure, based on recursive residuals is proposed and developed The power of the test procedure to identify one or more outliers is investigated through simulation, and its relevance to the number and configuration of the outlier.

  • PDF

Numerical simulation of residual currents by diagnostic multi-level model in Kwangyang Bay, Korea (다층 진단 모델에 의한 광양만의 잔차류 수치 실험)

  • 추효상;이병걸;이규형
    • Journal of Environmental Science International
    • /
    • v.11 no.1
    • /
    • pp.41-56
    • /
    • 2002
  • In order to estimate the quantitative roles of the tide induced residual currents, density currents and wind driven currents on the residual currents in Kwangynag Bay Korea, numerical experiments with a diagnostic multi-level model were carried out. Density currents were calculated from the temperature and salinity data observed in January, May, August and November 1998. Anti-clockwise circulations are formed at the western inner part of the bay, the location from the east of Myodo Is. to the south of POSCO Co. and the place between Yeosu peninsula and Namhae Is. from the calculation results of the tide induced residual currents. Velocities of the density currents are less than 3cm/s at the western inner part of the bay and about 5cm/s at the southern entrance of the bay. Density currents get strong in summer and weak in autumn. Wind driven currents at the surface layer flow in the directions of the given winds which are the daily mean winds when the temperature and salinity observations are carried out. In the middle and lower layers, however the wind driven currents flow in the opposite direction to the surface currents as supplementary currents. The surface wind driven currents are greater than the tide induced residual currents or the density currents. The calculated residual currents including the tide induced residual currents, density currents and wind driven currents agree with the results of the current observations approximately. In the Bay, the wind driven currents affect on the residual currents greatestly and tide induced residual currents and density currents do in the second place and the third place.

A Study on Diagnostic Model of Cerebrovascular Disease for Ubiquitous Health Care (U-헬스 케어 환경에서 뇌혈관 질환 진단 모델 연구)

  • Lee, Hyun-Chang;Kim, Jeong-Gon
    • Journal of the Korea Society of Computer and Information
    • /
    • v.11 no.6 s.44
    • /
    • pp.107-111
    • /
    • 2006
  • According to IT(information technology) industry progress. our life is gradually convenient. The proliferation of environmental pollution and the threat of diseases proportional to the progress comes to be high gradually. We must prevent dangerous diseases which threatens the life of the human. Or we are bumped against irrevocable serious situation. In spite of the situation. managing one's own health against modern busy lifestyle is very difficult. Therefore, we need to manage our health situation by using sensors based on ubiquitous IT environment. In this paper. we propose a diagnostic model which is able to diagnose and prevent a cerebrovascular disease based on ubiquitous technology. Also. as a step of implementing the u-health care diagnosis system, the diagnosis model of cerebrovascular disease plays an important role to decide a clinic result. In the future, by using this model. we may improve our welfare and health.

  • PDF

Developmental Disability Animal Model Based on Neonatal Lipopolysaccharide with Altered 5-HT Function

  • Kim, Jae-Goo;Kim, Min-Soo;Lee, Se-Oul;Kim, Gun-Tae;Lee, Jong-Doo;Kim, Dong-Goo
    • The Korean Journal of Physiology and Pharmacology
    • /
    • v.11 no.3
    • /
    • pp.113-119
    • /
    • 2007
  • Developmental disability shows life-long behavioral abnormality with no significant physical malformation. This study was undertaken to develop an animal model for developmental disability by using two-factor approach. Lipopolysaccharide (LPS), a bacterial toxin, and NAN-190, a $5-HT_{1A}$ receptor antagonist, were administered to Sprague-Dawley rats on postnatal day (PND) 5 to induce inflammation and an altered 5-HT system, respectively. Long-term alteration of behavior occurred in the drug-treated groups. The LPS-treated group showed impaired motor coordination in the Rota-rod test. The LPS- treated or both LPS and NAN-190-treated groups showed impaired fore-paw muscle power in the wire maneuver test. These groups also showed decreased white matter volume and increased serotonergic fibers. The LPS and NAN-190-treated group also exhibited neurologic deficit in the placing reaction test and impaired equilibrium function in the tilt table test. The results showed that a variety of altered behaviors can be generated by two factor model, and suggested that combination of important etiologic factors and possible underlying defects is a promising strategy of establishing an animal model for developmental disabilities.

Diagnostics for Regression with Finite-Order Autoregressive Disturbances

  • Lee, Young-Hoon;Jeong, Dong-Bin;Kim, Soon-Kwi
    • Journal of the Korean Statistical Society
    • /
    • v.31 no.2
    • /
    • pp.237-250
    • /
    • 2002
  • Motivated by Cook's (1986) assessment of local influence by investigating the curvature of a surface associated with the overall discrepancy measure, this paper extends this idea to the linear regression model with AR(p) disturbances. Diagnostic for the linear regression models with AR(p) disturbances are discussed when simultaneous perturbations of the response vector are allowed. For the derived criterion, numerical studies demonstrate routine application of this work.

The Relationship between World Oil Price and Consummer Price Index in Korea (국제유가와 소비자물가의 변동)

  • Kim, Youngduk
    • Environmental and Resource Economics Review
    • /
    • v.9 no.2
    • /
    • pp.373-391
    • /
    • 2000
  • This paper investigates the existence of a long-run relationship between world oil price and consumer price index for Korea during 1983~1999. The cointegration and error correction modelling approaches have been applied. Empirical results suggest that there exists a long-run relationship among world oil prices. consumer prices, M2 and a production gap variable. The dynamic behavior of the relationship has been investigated by estimating a error correction model, in which the error correction term have been found significant. The error correction model has also been found to be robust as it satisfy almost all relevant diagnostic tests.

  • PDF

서비스기업의 시장지향성, 고객만족도, 기업성과에 관한 실증연구

  • 김용준;김진수
    • Journal of Distribution Research
    • /
    • v.3 no.1
    • /
    • pp.31-54
    • /
    • 1998
  • The purpose of this research is three-fold; 1, establish the causal model of market-orientation, customer satisfaction, employee satisfaction and firm's perfor-mance. 2. testify the hypothesis derived by the model on a service industry of fastfood franchise. 3. develop the diagnostic tool for managing the service firm from the perspective of CS. The results show us; 1. customer satisfaction increases the performance of franchise store. 2. employee satisfaction does not necessarily increases customer satisfaction in a short-run, however the long-run impact of employee satisfaction on customer satisfaction is conjectured to be increased. 3. Satisfaction Portfolio Analysis can be utilized as management tool to improve the customer satisfaction and employee satisfaction for service industry.

  • PDF