• Asian Pacific Journal of Cancer Prevention
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• 제14권11호
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• pp.6997-7005
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• 2013

Aim: To present an epidemiological and histological perspective of diseases of the gastrointestinal tract (including liver and biliary tract) at the Section of Histopathology, Department of Pathology, AKUH, Karachi, Pakistan. Materials and Methods: All consecutive endoscopic biopsies and resections between October 1 and December 31, 2012 were included. Results: A total of 2,323 cases were included. Carcinoma was overwhelmingly the commonest diagnosis on esophageal biopsies (69.1%); chronic helicobacter gastritis (45.6%) followed by adenocarcinoma (23.5%) were the commonest diagnoses on gastric biopsies; adenocarcinoma (27.3%) followed by ulcerative colitis (13.1%) were the commonest diagnoses on colonic biopsies; acute appendicitis (59.1%) was the commonest diagnosis on appendicectomy specimens; chronic viral hepatitis (44.8%) followed by hepatocellular carcinoma (23.4%) were the commonest diagnoses on liver biopsies; chronic cholecystitis was the commonest diagnosis (over 89%) on cholecystectomy specimens. Conclusions: Squamous cell carcinoma comprised 88.8% of esophageal cancers. About 67% were in the lower third and 56.5% were moderately differentiated; mean ages 49.8 years for females and 55.8 years for males; 66% cases were from South West Pakistan. Over 67% patients with gastric adenocarcinoma were males; mean ages 59 and 44 years in males and females respectively, about 74% gastric carcinomas were poorly differentiated; and 62.2% were located in the antropyloric region. About 63% patients with colorectal adenocarcinoma were males; mean ages 46.1 and 50.5 years for males and females respectively; tumor grade was moderately differentiated in 54%; over 80% were located in the left colon. In 21.2% appendicectomies, no acute inflammation was found. Acute appendicitis was most common in young people. Hepatitis C (66.3%) was more common than hepatitis B (33.7%); about 78% cases of hepatocellular carcinoma occurred in males; females comprised 76.7% patients with chronic cholecystitis; and 77.8% patients with gall bladder carcinoma. All resection specimens showed advanced cancers. Most cancers occurred after the age of 50 years.

• Asian Pacific Journal of Cancer Prevention
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• 제15권13호
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• pp.5487-5492
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• 2014

Ultrasonography is non-invasive and can give useful clues in the diagnosis of cervical lymphadenopathy, However, differential diagnosis is difficult in some situations even combined with color Doppler imaging. The present study was conducted to evaluate the clinical value of real time elastography in patients with unexplained cervical lymphadenopathy using a quantitative method. From May 2011 to February 2012, 39 enlarged lymph nodes from 39 patients with unexplained cervical lymphadenopathy were assessed. All the patients were examined by both B-mode ultrasound, color Doppler flow imaging and elastography. The method of analyzing elasto-graphic data was the calculation of the 10 parametres ("mean", "sd", "area%", "com", "kur", "ske", "con", "ent", "idm", "asm") offered by the software integrated into the Hitachi system. The findings were then correlated with the definitive tissue diagnosis obtained by lymph node dissection or biopsy. Final histology revealed 10 cases of metastatic lymph nodes, 11 cases of lymphoma, 12 cases of tuberculosis and 6 cases of nonspecific lymphadenitis. The significant distinguishing features for conventional ultrasound were the maximum short diameter (p=0.007) and absent of echogenic hilum (p=0.0293). The diagnostic accuracy was 43.6% (17/39 cases) and there were 17 patients with equivocal diagnosis. For elastography, "mean" (p=0.003), "area%" (p=0.009), "kurt" (p=0.0291), "skew" (p=0.014) and "cont" (p=0.012) demonstrated significant differences between groups. With 9 of the 17 patients with previous equivocal diagnoses (52.9%) definite and correct diagnoses could be obtained. The diagnostic accuracy for conventional ultrasound combined elastography was 69.2% (27/39 cases). There were differences in the diagnostic sensitivity of the two methods (p=0.0224). Ultrasound combined with elastography demonstrated higher rates of conclusive and accurate diagnoses in patients with unexplained cervical lymphadenopathy than conventional ultrasound. The quantitative program showed good correlation with the pathology of different lymph node diseases.

• 한국산학기술학회논문지
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• 제17권10호
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• pp.119-130
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• 2016

본 연구는 의사로부터 고혈압으로 진단받은 사람들을 대상으로 개인 건강행태 및 지역 보건의료수준이 고혈압의사진단에 미치는 영향을 파악하고자 실시하였다. 연구는 2010년도 지역사회건강조사대상 만 19세 이상 성인 229,229명을 대상으로 개인특성에 따른 고혈압 의사진단의 차이 비교는 카이제곱 검정을 사용하였으며, 개인 및 지역수준 변수를 고려한 고혈압 의사진단의 관련지표의 지역 간 변이 파악은 다수준 로지스틱회귀분석를 실시하였다. 연구결과 개인건강행태수준에서 연령수준이 높을수록, 최종학력이 높을수록, 기초생활수급이 무일 때, 체질량지수가 높을수록, 일회음주량이 많을수록 고혈압 의사진단 경험률이 높았다. 또한 보건의료기관을 이용한 사람이, 한 달 동안 혈압측정횟수가 높을수록, 주관적 스트레스 수준이 높을수록, 우울감 경험이 있을 때 고혈압 의사진단 경험률이 높았다. 반면에 고용형태가 임금근로자인 경우, 고용주 및 자영업자에서, 걷기일수가 많을수록, 현재 흡연여부 경험이 적을수록, 민간의료보험에 가입한 사람에서 고혈압 의사진단 경험률이 낮았다. 건강행태 및 지역의 보건의료수준에 따라, 고혈압의사진단에 미치는 영향이 크다는 것을 알 수 있었으며, 추후 많은 연구에서 지역수준을 고려한 다수준 분석이 필요할 것으로 사료된다.

• Pediatric Infection and Vaccine
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• 제30권3호
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• pp.139-144
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• 2023

농뇨는 가와사키병 환아의 약 30-60%에 동반되는 소견으로, 임상적 증후가 다 나타나지 않은 초기의 가와사키병 또는 불완전 가와사키병에서 요로감염으로 오인할 수 있으나, 불완전 가와사키병 진단에 중요한 검사실 소견 중 하나일 수 있다. 본 연구에서는 한국의 5세 미만 영유아에서 가와사키병 진단 전 요로감염으로 선행 진단 사례의 유병률과 역학적 위험인자를 평가하고자 한다. 건강보험심사평가원에서 제공하고 있는 보건의료 빅데이터 개방시스템 자료를 바탕으로 2007년 11월부터 2019년 10월까지 가와사키병과 요로감염으로 진료, 청구된 대상자에 대해 후향적 단면연구를 시행 하였다. 가와사키병 확정 진단 전 1주일 이내의 요로감염 선행 진단된 환아의 발생률을 계산하였고, 카이제곱 (χ² test) 검정을 실시하였다. 연령, 성별, 지역, 계절별 발생률에 대한 요로감염 선행 진단 여부에 대해 로지스틱 분석 (logistic regression)을 수행하였다. 연구 결과, 총 53,822명의 가와사키병 환자가 포함되었으며 그 중 304명 (0.56%)이 선행 요로감염 진단이 있었다. 12개월 미만에서의 요로감염 선행 진단률이 가장 높았으며 (0.95%), 4세와 비교했을 때 요로 감염 선행진단의 오즈비는 3.12 (2.05-4.77) 였다. 발열을 동반한 농뇨가 있는 영아의 일부에서는 불완전 가와사키병의 감별진단이 필요할 수 있다.

• 대한영상의학회지
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• 제82권6호
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• pp.1545-1555
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• 2021

목적 동료평가를 시행하여 원격판독 불일치의 정도와 불일치 판독의 임상적 의의를 세부전공분야와 촬영장비별로 평가하고자 하였다. 대상과 방법 한 국내 원격판독 의료기관에서 2018년과 2019년에 시행한 동료평가를 대상으로 세부전공분야와 촬영장비별로 판독 불일치를 분석하였다. 동료평가 점수를 적격 진단과 부적격 진단으로 분류하였고, 판독 불일치는 임상적 의의에 따라 무의한 불일치와 유의한 불일치로 분류하였다. 카이제곱 검증으로 통계를 시행하였다. 결과 총 1312건의 동료평가 중 부적격 진단은 117건(8.9%)이고, 총 462건의 진단 불일치 중 유의한 불일치는 104건(21.6%)이었다. 세부전공분야에서 부적격 진단율은 근골격(21.4%)이 가장 높았고(각각 p < 0.05), 복부(7.3%)는 신경두경부(1.3%)에 비해 높았다(p < 0.05). 유의한 불일치는 흉부(32.7%)가 복부(17.1%)와 근골격(19.5%)에 비해 높았다(각각 p < 0.05). 촬영장비에서 부적격 진단은 MR (16.2%)이 일반촬영(7.8%)에 비해 높았고(p < 0.05), 유의한 불일치는 차이가 없었다. 결론 동료평가를 통해서 원격판독의 부적격 진단과 임상적 유의한 불일치의 정도, 세부전공분야와 촬영장비에 따른 차이를 알 수 있었다.

• Neonatal Medicine
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• 제16권1호
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• pp.1-9
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• 2009

Seizures are the most common clinical manifestation of a neurologic insult during the neonatal period. Neonatal seizures continue to present a diagnostic and therapeutic challenge to pediatricians because the recognition and classification of neonatal seizures remains problematic, particularly when clinicians rely only on clinical criteria. Neonatal seizures can permanently disrupt neuronal development, induce synaptic reorganization, alter plasticity, and "prime" the brain to increased damage from seizures later in life. Since neonatal seizures, particularly status epilepticus, predict an increased risk for later epilepsy and other neurologic sequelae, accurate diagnoses are needed for aggressive antiepileptic drug use. The present review summarizes the pathophysiology, etiology, and diagnosis of neonatal seizures.

• 대한의용생체공학회:의공학회지
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• 제8권2호
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• pp.215-222
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• 1987

This paper describes the design of a real time arrhythmia detection system using five variables : heart rate, QS width, morphology, alls deviation, and ST segment. To detect individual variables for four patients, we designed multi-processor system. The results of the analysis derived from simulators and 50 patients are compared with the medical diagnoses. The results show that the analysis was able to detect irregularly occuring arrhythmia which does not show up in routine medical examination.

• Journal of Species Research
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• 제5권3호
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• pp.343-347
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• 2016

Two pleurostomatid ciliates, Amphileptus litonotiformis Song, 1991 and Kentrophyllum setigerum (Quennerstedt, 1867), were collected from the coastal waters of Korea. Their morphologies are described based on live observation and protargol impregnation, and their diagnoses and morphometrics are provided. Additionally, sequence information of small subunit ribosomal RNA obtained from two species were reported.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2005년도 학술대회 논문집 정보 및 제어부문
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• pp.490-492
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• 2005

Unattended continuous containment/surveillance systems for safeguards of nuclear facility result in large amounts of image and radiation data, which require much time and effort to inspect. Therefore, it is necessary to develop system that automatically pinpoints and diagnoses the anomalies from data. In this regards, this paper presents the nuclear material containment/surveillance system that integrates visual image and radiation data.

• 제어로봇시스템학회:학술대회논문집
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• 제어로봇시스템학회 1989년도 한국자동제어학술회의논문집; Seoul, Korea; 27-28 Oct. 1989
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• pp.957-961
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• 1989

This paper deals with test-pattern generation and diagnoses of pattern-sensitive faults in RAM by use of simple pseudorandom M-sequences with an emphasis to built-in structure of these schemes. The problems that may arise during their implementation are discussed and an approach to builtin testing of RAM by such a scheme is given not bothering too much about the silicon area required.