• Nuclear Engineering and Technology
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• 제54권10호
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• pp.3803-3810
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• 2022

OpenMC is a community-driven open-source Monte Carlo neutron and photon transport simulation code. The Weight Window Mesh (WWM) function and an automatic Global Variance Reduction (GVR) method was recently developed and implemented in a developmental branch of OpenMC. This WWM function and GVR method broaden OpenMC's usage in general purposes deep penetration shielding calculations. However, the Local Variance Reduction (LVR) method, which suits the source-detector problem, is still missing in OpenMC. In this work, the Weight Window Generator (WWG) function has been developed and benchmarked for the same branch. This WWG function allows OpenMC to generate the WWM for the source-detector problem on its own. Single-material cases with varying shielding and sources were used to benchmark the WWG function and investigate how to set up the particle histories utilized in WWG-run and WWM-run. Results show that there is a maximum improvement of WWM generated by WWG. Based on the above results, instructions on determining the particle histories utilized in WWG-run and WWM-run for optimal computation efficiency are given and tested with a few multi-material cases. These benchmarks demonstrate the ability of the OpenMC WWG function and the above instructions for the source-detector problem. This developmental branch will be released and merged into the main distribution in the future.

• 아시아태평양코퍼스연구
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• 제4권2호
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• pp.1-39
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• 2023

Recent research in usage-based Second Language Acquisition has provided new insights into second language (L2) learners' development of formulaic language (Wulff, 2019). The current study examines the use of phrase-frames, which are recurring sequences of words including one or more variable slots (e.g., it is * that), in written and oral production data from Asian learners of English across four proficiency levels (beginner, low-intermediate, high-intermediate, advanced) and native English speakers. The variability, predictability, and discourse functions of the most frequent 4-word phrase-frames from the written essay and spoken dialogue sub-corpora of the International Corpus Network of Asian Learners of English (ICNALE) were analyzed and then compared across groups and modes. The results revealed that while learners' phrase-frames in writing became more variable and unpredictable as proficiency increased, no clear developmental patterns were found in speaking, although all groups used more fixed and predictable phrase-frames than the reference group. Further, no developmental trajectories in the functions of the most frequent phrase-frames were found in both modes. Additionally, lower-level learners and the reference group used more variable phrase-frames in speaking, whereas advanced-level learners showed more variability in writing. This study contributes to a better understanding of the development of L2 phraseological competence.

• 한국산림과학회지
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• 제76권3호
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• pp.249-255
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• 1987

Forestry as with all land matters, under the Constitution, is a State matter. Thus the States, numbering 14, have considerable autonomy in decisions on forestry and related matters. However, the Federal Government, having jurisdiction over such issues as defence, education and research, endeavours to coordinate, standardise and advise the States on matters where the States have jurisdiction. However, forestry being a major revenue earner, is jealously guarded by the States. Under such circumstances and recognising the interdependencies of impacts of decisions at the State level, the institutional organisations play an important role in coordinating state activities to ensure that the benefits to the country as a whole are not sacrificed in favour of interests of individual state. Various legislative mechanisms have been established to ensure this coordinated effort. A National Forestry Council forms the apex of national political coordination. The Federal Forestry Department is responsible for coordination of developmental activities at the State level, which are implemented be the State Forestry Departments within Peninsular Malaysia. Research is carried out centrally by the Forest Research Institute of Malaysia(FRIM), a statutory body formed in 1985 from a research division of the Forestry Department. The Stares of Sabah and Sarawak have their own Forestry Departments, independent of the Federal Department, and each with its own research unit independent of FRIM. Tertiary education in forestry is the sole responsibility of the Agricultural University at Serdang with a campus for Diploma level training in Sarawak. In the developmental area in the State of Sabah, institutions have been formed to focus on specific areas of activities. The Sabah Foundation is responsible for the long term development of the State forests with a concession of about one million ha. Sabah Forest Development Authority(SAFODA) was formed to carry out reforestation of denuded areas. Sabah Forest Industries Ltd.(SFI) is responsible for the country's only integrated pulp and paper industry with its own afforestation program to support its resource supply. In Peninsular Malaysia various states have established State Corporations to manage large "sustained yield" concessions. While wildlife and state parks are managed by the respective forestry departments in Sabah and Sarawak, it is the responsibility of a separate department in Peninsula Malaysia called the Department of Wildlife and National Parks(under the Ministry of Science, Technology and Environment). Timber trade legislation and promotion in the Peninsular is the responsibility of the Malaysian Timber Industries Board(MTIB) for Peninsular Malaysia and the Sarawak Timber Industries Development Corporation(STIDC) in Sarawak. In the area of NGOs ; the Institute of Foresters Malaysia, is the professional body of forestry in the country. A Malaysian Forestry Society caters for the public participation and interest. Other environmentally related NGOs such as the Malayan Nature Society, the Environmental Protection Society, World Wildlife Fund, Friends of the Earth and the Consumers Associations also involve themselves in specific forestry activities. A number of timber trade associations are also formed by the private sector to assist the industries.

• Child Health Nursing Research
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• 제22권3호
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• pp.199-206
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• 2016

Purpose: This study was conducted to monitor the development of Korean premature infant at six-month age and to explore factors related to developmental status of the premature infants. Methods: Participants were 58 premature infants whose corrected age was six-months old and their mothers. The developmental states of infants were followed-up with the Korean Prescreening Developmental Questionnaire (KPDQ-II). Clinical characteristics of the infants were identified from the medical records. Other characteristics including Edinburgh Postnatal Depression Scale, husband's support, social support, and mother-infant attachment were assessed using self-report questionnaires from the mothers. Results: Forty three percent of the infants were in the group of questionable status of development on the KPDQ-II. There were significant differences between the premature infants with normal developmental status and those with questionable developmental status depending on gender ($x^2$=5.03, p=.034), gestational age (t=2.59, p=.012), hospital stay (p=.013), revised Neurobiologic Risk Score (p=.005) and mother-infant attachment score (t=2.12, p=.040). Conclusion: Mother-infant attachment, as well as physiological state of premature infants, is an important variable in early development. Therefore, early monitoring for the development has to be done for physiologically vulnerable premature groups. Also, providing proper nursing support to improve maternal attachment needs to be considered.

• Mycobiology
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• 제45권4호
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• pp.233-239
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• 2017

Drosophila melanogaster is a useful model organism that offers essential insights into developmental and cellular processes shared with humans, which has been adapted for large scale analysis of medically important microbes and to test the toxicity of heavy metals, industrial solvents and other poisonous substances. We here give a brief review of the use of the Drosophila model in medical mycology, discuss the volatile organic compounds (VOCs) produced by the opportunistic human pathogen, Aspergillus fumigatus, and give a brief summary of what is known about the toxicity of some common fungal VOCs. Further, we discuss the use of VOC detection as an indirect indicator of fungal growth, including for early diagnosis of aspergillosis. Finally, we hypothesize that D. melanogaster has promise for investigating the role of VOCs synthesized by A. fumigatus as possible virulence factors.

• Asian-Australasian Journal of Animal Sciences
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• 제22권1호
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• pp.7-12
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• 2009

Lmbr1 is regarded as a key gene that controls the digital model formation in early developmental stages of the chicken. However, there are few reports of lmbr1 expression levels and tendencies in 4-toe and 5-toe chicken species. Therefore, the objective of this study was to compare the lmbr1 expression in White Leghorn (4-toe) and Chinese Silky (5-toe). Firstly, total RNA was extracted from 14 different embryonic development stages (HH3 to HH31) in White Leghorn and Chinese Silky. Secondly, dramatic gene expression changes of lmbr1 were monitored by RT-PCR, which indicated a general up-down-up tendency with subtle differences between these two species. Moreover, Q-PCR reactions were performed to quantitate the expression level of lmbr1 in the 14 selected developmental stages. These data demonstrated a first lmbr1 expression peak of 18.68 and 15.32, a lmbr1 expression trough of 6.61 and 1.80, and a second lmbr1 expression peak of 22.33 and 12.48 in White Leghorn and Chinese Silky, respectively. Finally, embryonic in situ hybridization analysis identified that lmbr1 expressed in the ectoderm in HH21, HH23 and HH24 developmental stages in both species.

• 한국학교수학회논문집
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• 제12권4호
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• pp.493-508
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• 2009

본 연구는 실제적 발단과 잠재적 발달간의 거리, 즉 근접발달영역의 특징들을 조사하는 것이다. 선시험과 후시험이 18명의 대학생들을 대상으로 실시되었으며 반힐레 수준 이론을 통해 실제적 발달이 같은 두 학생이 잠재적 발달 조사를 위해 선발되었다. 인지-의사소통이론을 바탕으로 삼차원 면대칭에 대한 두 학생의 담화 특징들을 확인하였다. 잠재적 발달 조사결과 두 학생사이에 상당한 차이가 있었다. 수학교육연구에서 학생들의 근접발달영역을 조사하기위한 연구방법론적 시사점을 제안한다.

• 대한한의학회지
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• 제36권2호
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• pp.50-55
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• 2015

Infants with tuberous sclerosis complex (TSC) have a higher chance of experiencing seizures before the age of 1 year; in particular, they commonly accompany infantile spasms. In cases where infantile spasms resulting from TSC are drug-resistant, more severe neuro-developmental and cognitive impairments occur. This particular case dealt with an infant with TSC who continued to experience partial seizures and infantile spasms despite using two different kinds of antiepileptic drugs (AEDs). His spasms ceased on the seventh day of taking modified Yukmijihwang-tang (YMJ), at which point he stopped the use of all AEDs. He became seizure-free after a month of the treatment and modified hypsarrythmia was found to have been resolved in the electroencephalogram test. Until now, the infant has been taking YMJ for 16 months and is maintaining the seizure-free state without side effects. Moreover, his developmental status is continually improving, with a significant progress in language and cognitive-adaptive abilities. Such results suggest that YMJ can serve as an alternative treatment option for refractory epilepsy.

• Molecules and Cells
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• 제41권8호
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• pp.753-761
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• 2018

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is identified as a signaling adaptor protein that regulates bone metabolism, immunity, and the development of several tissues. Therefore, its functions are closely associated with multiple diseases. TRAF6 is also involved in the regulation of hematopoiesis under steady-state conditions, but the role of TRAF6 in modulating hematopoietic stem and progenitor cells (HSPCs) during the developmental stages remains unknown. Here, we report that the deletion of TRAF6 in hematopoietic lineage cells resulted in the upregulation of HSPCs in the fetal liver at the prenatal period. However, in the early postnatal period, deletion of TRAF6 drastically diminished HSPCs in the bone marrow (BM), with severe defects in BM development and extramedullary hematopoiesis in the spleen being identified. In the analysis of adult HSPCs in a BM reconstitution setting, TRAF6 played no significant role in HSPC homeostasis, albeit it affected the development of T cells. Taken together, our results suggest that the role of TRAF6 in regulating HSPCs is altered in a spatial and temporal manner during the developmental course of mice.

• 한국인구학
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• 제20권2호
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• pp.181-198
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• 1997

사회발전에 관한 기존이론의 분석틀을 비판적으로 검토하는 이 글은 급속한 경제성장에 따른 사회적 결과로서 삶의 질의 과정에 대해 그 인과 구조를 조망함으로써 정치경제적 요소보다는 사회적 조건에 대한 합리적 선택이론의 명제를 제시한다. 아울러 근대의 지배적 담론이었던 시간과 역사에 가려져 있던 공간을 사회적 관계의 산물이자 동시에 사회적 과정과 끊임없이 상호작용하는 역동적인 대상으로 접근한다. 곧 삶의 질 자체가 공간적으로 생산되며, 복지국가의 실현 역시 그것이 실현될 수 있는 열린 사회의 공간을 전제로 한다는 것이다. 분석의 초점은 부분적으로 국가구조의 결과이면서 동시에 국가로부터의 자율성을 기반으로 하는 발전경로의 역사적인 흐름과 성격을 파악하는 데 두고 있다. 또한 국가권력과 시민사회 세력간의 힘의 역학관계를 바탕으로 성장위주의 발전전략으로부터 삶의 질을 찾아가는 사회적 변동에 관한 이론적 함의를 제시함으로써 사회발전의 의미를 재성찰하고 앞으로의 발전과정에 대해 조심스럽게 진단하고자 한다. 연구의 결과는 시민사회가 국가권력과의 대응관계에서 어떻게 그 성격을 변화시켜 왔으며 또 삶의 질을 둘러싼 사회적 조건은 어떻게 형성해 왔는가를 보여준다. 특히 국가의 성장위주의 경제정책과 억압적 사회정책은 역설적으로 경제성장의 주체인 사회적 공간의 인내력을 감소시킴으로써 사회변동의 틀을 마련해 준다. 더욱이 국가권력의 질적으로 상이한 측면을 반영한 질적 분석에 따르면, 국가중심적 이론은 국가의 적극적인 경제개입과 사회통제를 강조함으로써 사회의 다른 영역을 등한시함과 동시에 삶의 질을 위한 사회적 조건을 규명하는데 한계를 지님으로써 그 이론적 내용을 수정해야 할 필요성이 있다. 반대로 노동 및 환경운동에 직접적으로 또는 간접적으로 영향력을 행사하는 시민사회의 성립과 공고화과정은 한국에서 복지국가의 형성과 삶의 질을 위한 실질적 노력을 제고하는 데 필수적인 요소로 나타나고 있다. 한국의 지탱가능한 사회발전에 대한 이론적 전망은 공공-민간 부문의 협력체계에 입각한 국가재정의 견고성에 의해 삶의 질의 사회적 공간을 제공, 확산하는 데 달려있으며, 유럽의 경우에서와 같이 과도한 복지지향의 사회정책과 형평성의 원리는 동시에 견제됨을 요구한다. 이러한 성장과 분배의 양립가능성을 조절하는 균형점으로서 삶의 질에 관한 연구는 발전과정과 사회정의와 관련하여 다른 역사적·문화적 조건 위에서 그 일반화의 수준을 검토하는 작업을 미래의 탐구영역으로 남겨놓고 있다.