• Title/Summary/Keyword: developmental pattern

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The Effect of Short-Term Intensive Sensory Integration Therapy Program on a Child with Sensory Modulation Disorder(Mixed Pattern) : Case Study (혼합형 감각조절장애 아동에 대한 단기집중 감각통합치료 프로그램의 효과-사례보고)

  • Kim, Eun-Young;Ji, Seok-Yeon
    • The Journal of Korean Academy of Sensory Integration
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    • v.4 no.1
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    • pp.37-46
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    • 2006
  • Objective : This single-subject study explored the effect of short-term intensive sensory integration therapy program which was provided in a 2006 sensory integration treatment course on adaptive response of a four-year-girl with sensory modulation disorder(mixed pattern). Method : Based on results of the assessment to the child, her therapist offers an organized sensory integration program during four days. Results : Improvement of child's movement quality and variety in physical environment in therapy rooms and interaction with her therapist were observed. Conclusions : This report of the case will be helpful for occupational therapists who plan to intervent with a short-term intensive sensory integration therapy program. In addition, the need for consideration of consultation with the child's parents is discussed.

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Innovation Policies and Locational Competitiveness : Lessons from Singapore

  • Ebner, Alexander
    • Journal of Technology Innovation
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    • v.12 no.2
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    • pp.47-66
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    • 2004
  • The relationship between innovation policies and locational competitiveness has emerged as an important area in the analysis of economic development, reflecting both the centralisation and decentralisation of globalising economic activities. The underlying spatial and institutional components are subject to a pattern of cumulative causation in which strategic interventions of policy actors exercise a decisive role in shaping competitive advantages, while promoting interactions with local and foreign partners both from the private and public sectors. The Singaporean development experience illustrated these strategic interdependencies of innovation policies and locational competitiveness. Based on her role as a manufacturing and service hub, Singapore is viewed as an infrastructural nodal point which is interconnected to global production networks. Paralleling efforts in the domain of technological innovation, Singapore's policies for locational competitiveness aim at an adaptive harmonisation of the needs of international investors with local developmental objectives. This orientation characterises also current efforts in promoting Singapore as a knowledge agglomeration with a distinct science base, expanding R&D operations and an innovation-driven pattern of economic development. In conclusion, the locational rationale of Singapore's innovation policies provides lessons for dealing with the spatial and institutional implications of technological globalisation.

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Esterase Isozyme Banding Pattern in Legume Seedings (콩과 식물의 Seeding Esterase Isozyme Banding Pattern에 관한 연구)

  • 이성규
    • Journal of The Korean Society of Grassland and Forage Science
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    • v.11 no.3
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    • pp.158-161
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    • 1991
  • Horizontal starch gel electrophoresis, follow by enzyrne-specific staining, separate and visualize several legume esterase isozyme. Using extracts prepared from cotyledon, radicle and plumule of legume seedlings germinated 5 days. The results were as follows. 1. The number and staining intensity of esterase isozyme bands varies depending on the plant species. tissues and developmental stage. 2. Bands in the cotyledon of field bean seedling expressed 4 and 1 in radicle. 3. In soybean cultivars, cotyledon of IIwangkum-kong had 3 bands and 1 band in the examined tissues of Paldal-kong and Jangkyung-kong seedling. 4. The cotyledon and radicle of french bean seedling had 3 bands, respectively. 5. The highest esterase isozyme activity appears to be expressed in the cotyledon and radicle of french bean, as indicated by intensity of stain, with the Paldal-kong particulary active.

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Ultrastructural Pattern of Synapses in the Rat Neostriatum during Postnatal Development (출생후 성장과정의 흰쥐 새줄무늬체에서 신경연접의 구조적 변동)

  • Lee, Hee-Lai
    • Applied Microscopy
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    • v.25 no.4
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    • pp.1-8
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    • 1995
  • This study was performed to analyze the morphological changes of synapses during early postnatal periods. Neonatal rats were grouped by 3, 7, 14, 21, 28 and 42day old, and observed the ultrastructural pattern of the synapses in the neostriatum by transmission electron microscope. 1. The number of synapse, the length of postsynaptic thickening and the amount of synaptic vesicles markedly increase during postnatal development 2. The proportion of asymmetric and curved synapses gradually increase by developmental periods. From the above results, it is suggested that the size of synapse increase during post-natal period, and asymmetric synapse are formed from the symmetric type and curved synapse are formed from the plane type.

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Control of Morphological Development and Transformation of Curves (곡선의 형태학적 성장과 변환의 제어 방법)

  • Lee, Joo-Haeng;Park, Hyung-Jun
    • Korean Journal of Computational Design and Engineering
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    • v.12 no.5
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    • pp.354-365
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    • 2007
  • We present novel methods to generate a sequence of shapes that represents the pattern of morphological development or transformation of Bezier curves. The presented methods utilize the intrinsic geometric structures of a Bezier curve that are derived from rib and fan decomposition (RFD). Morphological development based on RFD shows a characteristic pattern of structural growth of a Bezier curve, which is the direct consequence of development path defined by fans. Morphological transformation based RFD utilizes development patterns of source and target curves to mimic the theory of evolutionary developmental biology: although the source and target curves are quite different in shapes, we can easily find similarities in their younger shapes, which makes it easier to set up feature correspondences for blending them. We also show that further controls on base transformation for intensity of feature blending, and extrapolation can compensate the immaturity of blended curves. We demonstrate the experimental results where transformation patterns are smoother and have unique geometric style that cannot be generated using conventional methods based on multi-linear blending.

Hypomethvlation of DNA with 5-Azacvtidine Alters Chromosome Replication Patterns in Cultured Human Lvmphocvtes (배양 인체 백혈구의 chromosome replication에 미치는 DNA hypomethylation의 영향)

  • 원태웅;이석우김우갑
    • The Korean Journal of Zoology
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    • v.37 no.4
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    • pp.437-477
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    • 1994
  • The DNA replication of human Iyrnphocvtes was studied using Bromodeo3fyuridine incorporation. The characteristic patterns of dvnamlc banding were analysed. Human chromosomal ONA was synthesized in a segmental but highly coordinated fashion. Each chromosome replicates according to its innate pattern of chromosome structure (bandinsl. R-positive bands are demonstrated as the initiation sites of DNA synthesis, and G-bnads initiate replication after it has been completed in the autosomal R-bands. Many researchers demonstrated that developmental or induced methvlation of DNA can inactivate the associated gene loci. Such DNA methylation can be reversed and specific genes reactivated by treatment with 5-azacvtidine. We treated the hvpomethvlating agent 5-azacvtidine and tested for changes of DNA replication pattern. Treatment with 5-azacytidine causes an advance in the time of replication. These observed changes in timing of replication suggest that DNA methvlation may modify regional groups of genes in concert.

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Constructing Demand and Supply Forecasting Model of Social Service using Time Series Analysis : Focusing on the Development Rehabilitation Service (시계열 모형을 활용한 사회서비스 수요·공급모형 구축 : 발달재활서비스를 중심으로)

  • Seo, Jeong-Min
    • The Journal of the Korea Contents Association
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    • v.15 no.6
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    • pp.399-410
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    • 2015
  • The primary goal of the study is to examine the possibility of applying the time series model to forecasting demand and supply of social services. In the study, we used survey data based on a nationally represented sample which is secondary processed data. We selected developmental rehabilitation service. The analysis, we made models of a demand and a supply using time series analysis. Utilizing the estimates, we identified each model's pattern. This study provides an empirical evidence to suggest benefits of using the time series model for forecasting the demand and the supply pattern of newly introduced social services. We also provide discussions on policy implications of utilizing demand and supply time series models in the process of developing new social services.

Effects of Nonylphenol on the Secretion of Catecholamines and Adrenocortical Hormones from Short-Term Incubated Rat Adrenal Glands

  • Hee-Su Kim;Yong-Pil Cheon;Sung-Ho Lee
    • Development and Reproduction
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    • v.27 no.4
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    • pp.213-220
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    • 2023
  • Previously, we showed that a chronic-low-dose nonylphenol (NP) exposure resulted in histological changes with sexually dimorphic pattern in rat adrenal glands. We hypothesized that such structural changes are closely related to the hormonal secretory patterns. To test this hypothesis, we developed the short-term adrenal incubation method, and measured the levels of catecholamines and cortical steroids using the high-performance liquid chromatography with electrochemical detection (HPLC-ECD) and specific enzyme-linked immunosorbent assay, respectively. The norepinephrine (NE) levels in media from NP-treated female adrenal, except 100 pM NP, were significantly increased [control (CTL) vs 1 nM NP, p<0.001; vs 10 nM NP, p<0.05; vs 100 nM NP, p<0.001; vs 1 µM NP, p<0.01]. The NE secretion from male adrenal was higher when treated with 100 nM and 1 µM NP (CTL vs 100 nM NP, p<0.05; vs 1 µM NP, p<0.05, respectively). The aldosterone level in the female adrenal media treated with 100 pM NP was significantly decreased, on the other hand, that of media treated with 10 nM NP was significantly increased (CTL vs 100 pM NP, p<0.05; vs 10 nM NP, p<0.01). In male adrenal media, the aldosterone levels of 10 nM, 100 nM and 1 µM NP-treated media were significantly declined (CTL vs 10 nM NP, p<0.001; vs 100 nM NP, p<0.001; vs 1 µM NP, p<0.001). These results showed the NP treatment altered secretory pattern of aldosterone from adrenals of both sexes, showing sexual dimorphism. It may be helpful for understanding possible adrenal pathophysiology, and endocrine disrupting chemicals-related sexually dimorphic phenomena in adrenals.

An Architectural Pattern Recommendation Method Based on a Quality-Attributes Trade-off Analysis (품질속성의 트레이드오프 분석을 통한 아키텍처 패턴 추천 방법)

  • Park, Hyeon-ju;Lee, Seok-Won
    • Journal of KIISE
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    • v.44 no.2
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    • pp.148-162
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    • 2017
  • Recently, the accomplishment of a system's quality attributes requires the negotiation of increasingly complex requirements, and this is because the contextual and developmental environments in which software is used has undergone broad changes. Nevertheless, with regard to most architectural designs, many of the proportions depend on the architect's intuition. Moreover, even if reusable architectural patterns are adapted to an architectural design, common schemas for the description of their use are nonexistent, and it is difficult to make a comparison for the selection of an appropriate systemic pattern because the focus of the schemas is not the user's perspective. To achieve a fast initial-design decision, this paper suggests new schemas that reduce the distance between the quality attribute requirements and the design by reinterpreting architectural patterns from the user's perspective. Also, based on the reconstructed pattern model that is derived from the use of the new schemas, an architectural-pattern recommendation method (APOQATo) for which the trade-off and the constraints that are due to the design decision are considered is provided as well as the advantages of the architectural pattern for which the quality attributes are satisfied.

Spatio-temparal Pattern Formation of Abdominal Muscle in Xenopus Iaevis

  • Ko, Che-Myong;Chung, Hae-Moon
    • Animal cells and systems
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    • v.1 no.2
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    • pp.329-335
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    • 1997
  • The final pattern of the skeletal muscle of a vertebrate depends on the position-specific behavior of the muscle precursor cells during early developmental process and the abdominal muscle is made of cells which migrate a relatively long distance from their original tissue, myotome of dorsal mesoderm. We report the spatia-temporal migration pattern of abdominal muscle in Xenopus laevis by in situ hybridization and immunohistological studies. Shortly after hatching tadpole stage (stage 31/32), a group of myotomal cells detaches from the lower tip of the second somite and migrates ventrally to the lower position of abdomen. At stage 34/35, a second cell group migrates away from the third somite. Total 7 myotomal cell groups migrate ventrally one by one from the second to eighth myotome along their own pathways through the cell free space located between epidermis and subepidermal layer of the abdomen. During migration, the sizes of the cell groups (abdominal muscle anlagens) are increased to several tens fold. Around stage 40 all the abdominal muscle anlagens reaches their final positions and are interconnected side by side rostrocaudally. They are also connected to other types of muscles, forming a large multisegmented abdominal muscle. Heat shock study suggests that the disruption of segmentation of somites does not block the detachment of abdominal muscle anlagen, though the treatment gave stage- and dosagedependent effects on the migration speed.

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