• Title/Summary/Keyword: developmental origins

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When do Children form Views about Origins, and what Factors Affect the Formation of These Views?

  • Cho, Jung-Il;Choi, Gyu-Shik
    • Journal of The Korean Association For Science Education
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    • v.27 no.6
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    • pp.465-476
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    • 2007
  • Whether and when naturalistic or supernaturalistic explanations of the origins of sun and earth, humans, life and species change with development was explored in a questionnaire and interviews with 32 first graders and 32 second graders, and in a questionnaire with 34 third graders, 32 sixth graders and 38 eighth graders. Participants were also asked about factors affecting their explanations in the questionnaires. Even the first and second graders could consistently provide supernaturalistic or naturalistic explanations on both the origins of sun and earth, and of humans. There was an age-related developmental shift from supernaturalistic to naturalistic explanation. As for origins of species, most of the first and second graders held the spontaneous generationist explanation, and after the third grade their views divided into evolutionist and creationist explanations. Students' explanations of species origins were established by the sixth grade through a transitional stage in the third grade. At the first and second grade levels, books and the children's own reasoning mainly influenced the views of origins, whereas parents and school were not perceived as being important. For the third graders and higher-grade levels, several factors, including parents and religion, were perceived as being important. These results show that explanations of origins start to develop earlier than or during the first grade, and are established by the sixth grade; moreover, the formation of these views is affected by several factors in addition to development.

Synaptic Plasticity in Angelman Syndrome

  • Chung, Lee-Yup
    • Development and Reproduction
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    • v.16 no.3
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    • pp.169-175
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    • 2012
  • Angelman syndrome (AS) is a neurodevelopmental disorder characterized by intellectual disability and autism. The genetic cause is the absence of UBE3A, an E3 ubiquitin ligase, from the maternal chromosome which can arise from multiple origins. Recently discovered targets of Ube3a are important for activity dependent changes in synaptic transmission and spine morphology. Plasticity studies in an AS mouse model is important for basic plasticity research with regard to understanding protein homeostasis as well as the search for therapeutic targets for the patients. The progress on synaptic plasticity from this unique disorder is reviewed.

On Induction and Mathematical Induction (귀납법과 수학적 귀납법)

  • Koh, Youngmee
    • Journal for History of Mathematics
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    • v.35 no.2
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    • pp.43-56
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    • 2022
  • The 21st century world has experienced all-around changes from the 4th industrial revolution. In this developmental changes, artificial intelligence is at the heart, with data science adopting certain scientific methods and tools on data. It is necessary to investigate on the logic lying underneath the methods and tools. We look at the origins of logic, deduction and induction, and scientific methods, together with mathematical induction, probabilistic method and data science, and their meaning.

Efficiency of Female-Derived Donor Cells on High Postnatal Survival in Pig Cloning

  • Cho, Seong-Keun;Park, Mi-Rung;Kwon, Deug-Nam;Hwang, Kyu-Chan;Lee, Eun-Kyeong;Son, Woo-Jin;Kim, Jin-Hoi
    • Proceedings of the KSAR Conference
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    • 2004.06a
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    • pp.217-217
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    • 2004
  • The present study was conducted to investigate the developmental competency between male- and female-somatic cell derived nuclear-transferred porcine embryos, and the productive and survival efficiency of cloned male and female piglets. The potential of eggs receiving somatic cells to develop into blastocysts was not different among donor cells of different origins. (omitted)

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A long head of the biceps tendon confluent with the intraarticular rotator cuff: arthroscopic and MR arthrographic fndings

  • Kim, Kyung-Cheon;Rhee, Kwang-Jin;Shin, Hyun-Dae;Byun, Ki-Yong
    • The Academic Congress of Korean Shoulder and Elbow Society
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    • 2008.03a
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    • pp.162-162
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    • 2008
  • Many anomalous origins of the long head of the biceps tendon (LHBT) have been reported. However, developmental anomalies of the LHBT are rarely encountered in daily practice. We report a patient with an anomalous LHBT that was adherent to and confluent with the rotator cuff throughout its intra-articular course and present the clinical, magnetic resonance arthrography, and arthroscopic findings.

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Early nutrition and adult health: Perspectives for international and community nutrition programs and policies

  • Hoffman, Daniel J.
    • Nutrition Research and Practice
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    • v.4 no.6
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    • pp.449-454
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    • 2010
  • Recent economic changes throughout the world, either development or crises and recessions, have prompted a host of nutrition related problems, including a decreased prevalence of undernutrition, an increase in the prevalence of diet related diseases, widespread food insecurity as crop prices increase, and so on. In addition, evidence is mounting that suggests that exposure to poor nutrition early in life is a predisposing factor for chronic diseases in adulthood. Thus, the role of international or community nutrition professionals is vital to not only studying and understanding the interplay between economics, food policy, and health, but also to improving the ability to intervene and prevent many problems related to food insecurity in developed and developing countries. The purpose of this review is to outline and describe these issues as a means to open discussion on how to best alleviate major nutrition problems in the world.

The interaction between gut microbiome and nutrients on development of human disease through epigenetic mechanisms

  • Lee, Ho-Sun
    • Genomics & Informatics
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    • v.17 no.3
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    • pp.24.1-24.8
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    • 2019
  • Early environmental exposure is recognized as a key factor for long-term health based on the Developmental Origins of Health and Disease hypothesis. It considers that early-life nutrition is now being recognized as a major contributor that may permanently program change of organ structure and function toward the development of diseases, in which epigenetic mechanisms are involved. Recent researches indicate early-life environmental factors modulate the microbiome development and the microbiome might be mediate diet-epigenetic interaction. This review aims to define which nutrients involve microbiome development during the critical window of susceptibility to disease, and how microbiome modulation regulates epigenetic changes and influences human health and future prevention strategies.

Recent Progress on Skin-Derived Mesenchymal Stem Cells in Pigs

  • Kumar, B. Mohana;Patil, Rajreddy;Lee, Sung-Lim;Rho, Gyu-Jin
    • Reproductive and Developmental Biology
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    • v.36 no.4
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    • pp.283-290
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    • 2012
  • Skin serves as an easily accessible source of multipotent stem cells with potential for cellular therapies. In pigs, stem cells from skin tissues of fetal and adult origins have been demonstrated as either floating spheres (cell aggregates) or adherent spindle-shaped mesenchymal stem cell (MSC)-like cells depending on culture conditions. The cells isolated from the epidermis and dermis of porcine skin showed plastic adherent growth in the presence of serum and positively expressed a range of surface and intracellular markers that are considered to be specific for MSCs. The properties of primitive stem cells have been observed with the expression of alkaline phosphatase and markers related to pluripotency. Further, studies have shown the ability of skin-derived MSCs to differentiate in vitro along mesodermal, neuronal and germ-line lineages. Moreover, preclinical studies have also been performed to assess their in vivo potential, and the findings appear to be effective in tissue regeneration at the defected site after transplantation. The present review describes the recent progress on the biological features of porcine skin-derived MSCs as adherent cells, and summarizes their potential in advancing stem cell based therapies.

Experiences as Consumers: In-Depth Interview of Thai Students Studying in Korea

  • Cheon, Hye-Jung;Poraksa, Sirin
    • International Journal of Human Ecology
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    • v.12 no.1
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    • pp.75-85
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    • 2011
  • This study aims to understand the experiences as consumers of Thai students studying in Korea. "Study Korea Project" which is a drive to globalize local universities by attracting more oversea students as a pull factor, and economic growth, values on education and Hallyu as push factors contribute to the increase the number of Thai students in Korea. In order to understand the experiences of Thai students as consumers studying in Korea, individual interviews were conducted. A total of 5 participants were asked about meaning of consumption in everyday life in Korea or any changes in consumption behavior compared to living in Thai. Three themes were identified through wholistic and selective approaches. First, all participants in the study said that they were surprised because of high living expense in Korea. Consequently, survival itself is too much for them and they have become more conscious of prices of goods. Secondly, since most participants in this study can control their own budget, they feel some degree of freedom and power of control of their own lives. This experience may help them to accomplish their developmental tasks during the transition to adulthood. Thirdly, they are easily imbued with Korean consumer culture. It causes various conflicts between buying and not-buying or friends gathering and saving money. Sometimes it makes them in stuck excessive consumption and financial problems. For a deeper understanding of oversea students' lives in Korea as consumers, further studies should take into consideration of not only their culture of origins, but also misconceptions that have accumulated around these students.