• The Journal of Korea Assosiation for Disability and Oral Health
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• v.6 no.1
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• pp.15-18
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• 2010

Sturge-Weber syndrome is a rare nonhereditary developmental condition that is characterized by a hamartomatous vascular proliferation involving the tissue of brain and face. The clinical features are characterized by port wine nevus following one or more divisions of trigeminal nerve, ocular involvement and neurologic involvement such as epilepsy, mental retardation, and contralateral hemiplegia. Oral manifestations include unilateral blood vessel expansion of the oral mucosa, vascular hyperplasia of gingiva, pyogenic granuloma-like massive hemangiomatous proliferation of oral mucosa, macrodontia, ipsilateral macroglossia, blood vessel anomaly of maxilla or mandible and abnormal tooth eruption sequence. This case report is about 11-year-old Sturge-Weber syndrome patient presented port wine nevus on the face, venous malformation on soft plate and buccal mucosa. In this case we performed simple extraction of several deciduous teeth and periodic oral hygiene management. If a patient with Sturge-Weber syndrome has to undergo dental surgery in affected areas of the mouth, great care must be taken to prevent severe hemorrhage.

• Preventive Nutrition and Food Science
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• v.16 no.4
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• pp.394-407
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• 2011

Better understanding of the complex factors leading to human diseases will be necessary for both long term prevention and for managing short and long-term health problems. The underlying causes, leading to a global health crisis in both acute and chronic diseases, include finite global health care resources for sustained healthy human survival, the population explosion, increased environmental pollution, decreased clean air, water, food distribution, diminishing opportunities for human self-esteem, increased median life span, and the interconnection of infectious and chronic diseases. The transition of our pre-human nutritional requirements for survival to our current culturally-shaped diet has created a biologically-mismatched human dietary experience. While individual genetic, gender, and developmental stage factors contribute to human diseases, various environmental and culturally-determined factors are now contributing to both acute and chronic diseases. The transition from the hunter-gatherer to an agricultural-dependent human being has brought about a global crisis in human health. Initially, early humans ate seasonally-dependent and calorically-restricted foods, during the day, in a "feast or famine" manner. Today, modern humans eat diets of caloric abundance, at all times of the day, with foods of all seasons and from all parts of the world, that have been processed and which have been contaminated by all kinds of factors. No longer can one view, as distinct, infectious agent-related human acute diseases from chronic diseases. Moreover, while dietary and environmental chemicals could, in principle, cause disease pathogenesis by mutagenic and cytotoxic mechanisms, the primary cause is via "epigenetic", or altered gene expression, modifications in the three types of cells (e.g., adult stem; progenitor and terminally-differentiated cells of each organ) during all stages of human development. Even more significantly, alteration in the quantity of adult stem cells during early development by epigenetic chemicals could either increase or decrease the risk to various stem cell-based diseases, such as cancer, later in life. A new concept, the Barker hypothesis, has emerged that indicates pre-natal maternal dietary exposures can now affect diseases later in life. Examples from the studies of the atomic bomb survivors should illustrate this insight.

• The Journal of Korean Physical Therapy
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• v.11 no.2
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• pp.51-59
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• 1999

Standing up from a supine and prone position is very important for physical independence. All kinds of patients have a bed rest or lying on floor without special care. Even though the patient had complete from illness. He must train the functional activities before discharge. There are many method for the functional activity training. Likewise, sing of reflex, voluntary movement for muscle strength increasing, but clinically ideal method is approaching with motor developmental stage. Supine and prone progression of proprioceptive neuromuscular facilitation have a ideal reason. That is reflex integratation, development of muscle tone, develop of motor control, dynamic and static, motor behavior and cognition.

• Neonatal Medicine
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• v.15 no.2
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• pp.123-133
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• 2008

Purpose: The purpose of this study was to determine the outcomes of extremely low birth weight infants (ELBWI) who were born at the Asan Medical Center and evaluate the recent status of neonatal intensive care and associated problems. Methods:We retrospectively evaluated 120 inborn ELBWI who were admitted to the NICU of the Asan Medical Center between 2003 and 2006. The survival rate, neurodevelopmental outcomes, maternal and infant factors, and infant mordibities were evaluated and the relationships with survival and catch-up growth were investigated. Results:The survival rate of the ELBWI was 82% at a mean gestational age of 27+2 weeks, and with a mean birth weight of 801.3${\pm}$129.0 g. The duration of hospitalization was 85.7${\pm}$27.2 days, the duration of O2 use was 43.9${\pm}$35.4 days, and the duration of ventilatory support was 20.9${\pm}$20.9 days among the survivors. The incidence of respiratory distress syndrome, chronic lung disease, severe intraventricular hemorrhage, and periventricular leukomalacia were 41.8%, 61.2%, 3%, and 4%, respectively. The mean mental developmental index and psychomotor development index of Bailey Scales of Infant Development (II) at follow-up were 83.4${\pm}$18.2 and 83.3${\pm}$20.3, respectively. Among the infants who had >18 months of follow-up, 50.8% had catch-up growth at 12 months. Conclusion:The survival rate of ELBWI has improved; however, the morbidities remain high, thus indicating further efforts must be implemented to reduce morbidity and improve neurodevelopmental outcomes.

• Korean Journal of Childcare and Education
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• v.11 no.3
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• pp.129-148
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• 2015

The purpose of this study was to look into trends in research concerned with children's counting in Korea. A total of 59 studies on counting including journal articles, master's & doctoral theses were analyzed in terms of the period of time, content, and research methods. The results showed that 1) ${\frac{1}{3}}$ of the total studies on counting were published in 2001~2005, 2) the most frequent content was the developmental trend of young children's counting ability and then the relation between counting ability and various mathematical competence, 3) most of the studies targeted normal early childhood children from 3~5 years old and used the quantitative method. These results showed that the domestic research on counting have limits in the research topics, subjects, and methodology. The researcher presents three suggestions for further research. Frist, topics that are not enough revealed in the previous studies, for examples, counting backwards, counting by collections such as tens, fives, twos, and counting errors in young children need to be further studied. Second, counting behavior and ability of young children under 3 years olds need to be investigated. Third, there is a need to increase the studies using qualitative methods.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.3
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• pp.409-420
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• 2002

At once Medicine of East and West have the same purpose in treating, but there is a difference between the method of medical care and the view/slant on a disease each other. In the East Medicine, It is very difficult to explain the concept of Hwalhyulhwau but it is one of the way to cure cancer for long time. Be based on the theory of the East Medicine, research single medicine's anti-cancer effect among the natural products that has anti-cancer function. Moreover, for the purpose of finding new way to cure and prevent against cancer, we, the researchers, divided into four groups for this research: Group one: survey new substance with anti-cancer effects from natural products. Group two: research of anti-cancer mechanism through the experimental studies. Group three: research of immune responses in anti-canncer effects from natural products. Group four: research of the inhibitory effect on metastasis through the anti-angiogenesis. From the above results, we blended efficacious medidcines against cancer and made new prescriptions of Soam-I and Soam-II. Now, we are studying on these new prescriptions. We speculate that Soam-I and Soam-II may be used for a new conceptional anticancer therapy.

• Korean Journal of Veterinary Research
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• v.49 no.1
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• pp.91-99
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• 2009

The concept about zoo is changing from the animal exhibition which simply contained the animals to the ecological zoo which has the function of preserving the animal species. At the central point of maintaining such role, the basic principle called the animal welfare lies obviously. Korea has applied the animal welfare principles such as carrying out the enrichment in the zoos since 2003, but there has not been any institutional device to evaluate and examine the application of the animal welfare so far. This study aims to confirm the level of animal welfare in Korea and suggest a developmental direction. For the purpose of the study, 12 zoos in Korea were evaluated according to 68 evaluating categories. 'Five Principles of Animal Welfare' in the Secretary of State's Standards of Modern Zoo Practice were selected and carried out as the evaluation categories, and the result, from the highest to lowest score given, was 'provision of food and water', 'provision of protection from fear and distress', 'provision of health care', 'provision of an opportunity to express most normal behaviours', and 'provision of a suitable enrichment' with the overall score of the entire Korean zoos being 2.86 (${\pm}$ 0.56). It was also confirmed that in order to improve the animal welfare of the Korean zoos, the animal management system must be standardized and organized. The evaluation and feedback, the active practice of animal welfare and its legislative support should be provided to establish an effective institutional device as well.

• Clinical and Experimental Pediatrics
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• v.63 no.1
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• pp.25-29
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• 2020

Background: Pain during the developmental period may adversely affect developing neuronal pathways and result in adverse neurodevelopmental, cognitive, and behavioral effects in later life. Immunizations, e.g., hepatitis B vaccine (HBV), administered at birth are painful experiences to which neonates are universally subjected. Purpose: Here we aimed to study and compare the effectiveness of various nonpharmacological pain management methods in newborns to enable the development of safe and effective analgesic methods for newborns. Methods: This prospective study was conducted at a tertiary care hospital in the Himalayan region. Three hundred term healthy neonates were divided into 6 groups of 50 each. Groups 1-5 were intervention groups, patients of which received a nonpharmacological intervention (breastfeeding, nonnutritive sucking, rocking, 25% sucrose, or distilled water) before the intramuscular HBV, while patients in group 6 received no intervention. The pain response in each group after the HBV injection was assessed and compared using cry duration and Douleur Aigue Nveau-ne (DAN) score, a behavioral acute pain rating scale for newborns. Results: Cry duration was decreased in all intervention groups, significantly so in the sucrose (19.90 seconds), breastfeeding (31.57 seconds), and nonnutritive sucking (36.93 seconds) groups compared with controls (52.86 seconds). DAN scores decreased significantly (P<0.05) at one or more points i.e. 30, 60, or 120 seconds in the breastfeeding and 25% sucrose intervention groups compared with controls. Conclusion: Oral sucrose and nonnutritive sucking are simple yet underutilized nonpharmacological interventions that effectively reduce pain in newborns.

• Korean Journal of Childcare and Education
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• v.1 no.1
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• pp.83-101
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• 2005

The present study applied Bayley Scales of Infant Development to Infants with High Risk to investigate the effects of determinants such as variables related to demographic variable, prenatal and perinatal and postpartal environments, and developmental indices in infancy. First, mental and motor development index were high in infants whose mothers had high in education, mothers had not had a disease during the pregnancy, mothers had not taken medicine during the pregnancy. Second, mental and motor development index were high in infants who had used an oxygen inhaler, incubator, and in infants who had been given a timely birth. Third, mental and motor development index were higher in infants whose mumbling and the initial speaking was normal than in infants whose development was late.

• Journal of Korean Academy of Nursing
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• v.24 no.2
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• pp.278-302
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• 1994

This article reviewed and analyzed 39 studies on self efficacy theory applied to health related behavior. The following analysis was done : 1) study subjects 2) measurement tools 3) analysis according to the type of research design(intervention re-search, explanatory research). Some findings are summarized as follows : The study subjects were both healthy people in various developmental stages and patients with various illnesses. The health related behaviors examined in the studies were also various including exercise, smoking cessation, self care behaviors, etc. The measurement of self efficacy was done with specific tools in most studies. In the tools, activities that measured the health behavior domain were listed according to increasing difficulty or contexual arrangement or in combination of both of them The analysis of 17 intervention research studies showed that generally the intervention program increased the self efficacy level of subjects and then the increased strongly self efficacy influenced behavioral changes. Most studies used more than one intervention method for increasing the self efficacy level. these were derived from sources of self efficacy suggested by Bandura. The analysis of 21 explanatory research studies showed that self efficacy strongly influenced behavior change and persistence. The major independent variable to affect the self efficacy was performance accomplishment in the past. Self efficacy explained more of the variance in health related behavior when it was applied with the variables in the health belief model, health promotion model, and reasoned action theory. On the basis of the above findings, the following suggestions are made : 1. For a desirable research design, self efficacy should be the intervening variable. That is, desirable designs would include intervention-self efficacy-behavior in intervention research studies and antecedent-self efficacy-behavior in explanatory research studies. 2. More prospective, longitudinal studies are needed to test the effect of self efficacy on persistence in health related behavior. 3. Studies comparing the effects of intervention methods are needed for each health related behavior, subject group, and context. 4. It is necessary to develop a reliable, valid measurement tool for self efficacy for each health related behavior. 5. Studies to differenciate the effect of self efficacy from that of outcome expectation on the health related behavior are necessary. 6. The antecedents of self efficacy should be investigated further.