• Biotechnology and Bioprocess Engineering:BBE
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• 제5권4호
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• pp.275-287
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• 2000

Fermentation strategies for recombinant protein production in Pichia pastoris have been investigated and are reviewed here. Characteristics of the expression system, such as phenotypes and carbon utilization, are summarized. Recently reported results such as growth model establishment, app58lication of a methanol sensor, optimization of substrate feeding strategy, DOstat controller design, mixed feed technology, and perfusion and continuous culture are discussed in detail.

• 한국CDE학회논문집
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• 제12권3호
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• pp.182-192
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• 2007

The reduction of product development time is exposed to the competitive pressure due to shortened product-and production technology lifecycles as well as increasingly dynamic markets. Specially in automobile companies, that is of major importance for designing die because it is a bottleneck process in the development of a new car. To improve this conventional design process, this paper describes how to design it fast and flexibly. This was done by a modular method using standard template and a feature and knowledge based design method along the design process.

• 약학회지
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• 제51권6호
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• pp.490-494
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• 2007

TRH (thyrotropin-releasing hormone) was chemically synthesized utilizing solution phase peptide chemistry for the process development of large scaled synthesis. All the synthetic steps performed in relatively mild conditions, higher yields, easier preparations, minimum racemizations, and separation and purification by recrystallizations.

• International journal of advanced smart convergence
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• 제4권2호
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• pp.84-93
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• 2015

This study is for the development of Cover Glass Grinding Processing System. This system is developed for manufacturing a mass product system grinding cover glasses with highly precise mechanism, and we improved resulted quality. In the development process, we developed a complete process technology through mechanical design, image processing technology, spindle control, mark identification algorithm etc. With this cover glass grinding development, we could developed process technology, image processing technology, organization mechanisms and control algorithms.

• 한국산학기술학회논문지
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• 제16권6호
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• pp.4137-4146
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• 2015

시스템의 규모와 요구기능은 점점 대형화되고 복잡해지고 있다. 이러한 시스템 개발 프로젝트의 성공적인 수행을 위해서는 프로세스에 따른 체계적인 시스템공학(SE)과 프로젝트관리(PM) 활동이 요구되고 있다. 시스템 개발 조직에서는 SE&PM 프로세스 개선 및 능력평가 모델인 CMMI를 채택하여 SE&PM 능력 확보에 노력하고 있으며, 이를 위해 조직의 비즈니스 특성에 맞는 조직 표준 프로세스를 구축하여 적용하고 있다. 하지만 시스템 개발조직 현장에서는 CMMI 프로세스영역 간 상호연관성에 대한 충분한 이해부족으로 조직 프로세스 구축에 어려움이 따르고 있다. 또한 SE와 PM활동은 시스템 개발에 있어서 상호 밀접하게 연관되어 있기 때문에 SE와 PM 프로세스는 상호 통합 및 연계성이 확보되어야만 효과적이고 효율적인 프로젝트 수행이 될 것이다. 본 논문에서는 시스템 개발 조직에서 CMMI 기반 조직 프로세스 구축에 참조되고 활용될 수 있는 조직의 SE&PM 통합 프로세스 아키텍처를 제시한다.

• 복식문화연구
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• 제24권6호
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• pp.743-755
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• 2016

This study aimed to reveal the designer's creative process in the development of clothing designs. The researcher has taken roles both as a design practitioner and an observer. The full process of design development was concurrently documented while working to solve a specific problem. This included noting down the concept, keywords, and detailed scratch ideas, as well as refining the design by collecting sketches and taking photos. Integrated data from the captured design process were analyzed based on Lamb and Kallal's apparel design framework, which included problem identification, construction of preliminary ideas, design refinement, prototype development, and evaluation. The functional, expressive, and aesthetic (FEA) criteria of the entire process were thus assessed. Additionally, five professional apparel reviewers evaluated the design project based on FEA criteria. The results showed the processes for identifying targets and intentions, extracting the main elements from sources, developing the major visual concepts, and making final adjustments. Ultimately, this study revealed how a designer manages each stage of the creative design process. Sharing such detailed observations of the design process can help refine the knowledge involved in each stage of the creative process, and provide guidance for instructors in design education.

• 대한조선학회 특별논문집
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• 대한조선학회 2013년도 특별논문집
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• pp.21-29
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• 2013

For the purpose of supporting Curved Blocks, pipe welding is commonly used on Curved panel. Typically, when it comes to attaching supporting pipe on heavy incurvated surface, it makes much loss in the process of design, cutting, welding. This paper gives proper methods to collecting problems and Core conflicts surrounding Support Pipe by using of TOC (Theory Of Constraints). Therefore drawing two solutions, pipe development program and NC generating from pipe development Data for Plate Cutting machine. It describes a process of erasing loss surrounding Support Pipe with "TOC Thinking process" and development of two programs in this paper.

• 한국정밀공학회지
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• 제15권11호
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• pp.46-57
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• 1998

Even though there are some studies on the deep drawing process and process planning, little study has been done on the methodology of process planning of secondary operations of deep drawing such as 'piercins'. In this paper, first, we systematized the methodology of the process planning of secondary operations on axisymmetric cup. Second we described the development of the expert system for their CAPP For these studies, we extracted the knowledge of their process planning from experts and analysed and systemized them. To develop the expert system, rule-based reasoning paradigm is used. The shape information of manufacturing features of secondary operations are manually input to the system through SUI. The process planning results are automatically connected to AutoCAD. We believe that the systematized process knowledge and the development of the expert system for its CAPP could give lots of aids to the associated field.

• 산업공학
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• 제25권3호
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• pp.309-318
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• 2012

Forecasting probability or likelihood of technology development success has been a crucial factor for critical decisions in technology management such as R&D project selection and go or no-go decision of new product development (NPD) projects. This paper proposes an analytic network process (ANP) approach to forecasting of technology development success. Reviewing literature on factors affecting technology development success has constructed the ANP model composed of four criteria clusters : R&D characteristics, R&D competency, technological characteristics, and technological environment. An alternative cluster comprised of two elements, success and failure is also included in the model. The working of the proposed approach is provided with the help of a case study example of MRAM (magnetic random access memory) technology.

• 한국병원경영학회지
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• 제1권1호
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• pp.170-187
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• 1996

This paper proposes a change process model for organization development in health care organizations and provide an OD case exemplar of nursing service unit at Virtual Hospital. This case exemplar was written in a narrative form rather than in an argumentative form as an embodiment of organization development process as is viewed from the cultural/interpretive perspective rather than from the technical/rational one. This case exemplar illustrates the change process which consists of four interrelated components: change intervention, organizational target variables, individual organizational member, and organizational outcomes. It also demonstrates the applicability of the narrative rationality which involves narrative probability and narrative fidelity to the story where the learning organization, shared governance, and empowerment are fully emplotted and enlivened. The implications for organization development in health care organizations are discussed.