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Idiopathic Hypertrophic Spinal Pachymeningitis with an Osteolytic Lesion

  • Jee, Tae Keun;Lee, Sun-Ho;Kim, Eun-Sang;Eoh, Whan
    • Journal of Korean Neurosurgical Society
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    • v.56 no.2
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    • pp.162-165
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    • 2014
  • Idiopathic hypertrophic spinal pachymeningitis (IHSP) is a chronic, progressive, inflammatory disorder characterized by marked fibrosis of the spinal dura mater with unknown etiology. According to the location of the lesion, it might induce neurologic deficits by compression of spinal cord and nerve root. A 58-year old female with a 3-year history of progressive weakness in both lower extremities was referred to our institute. Spinal computed tomography (CT) scan showed an osteolytic lesion involving base of the C6 spinous process with adjacent epidural mass. Magnetic resonance imaging (MRI) revealed an epidural mass involving dorsal aspect of cervical spinal canal from C5 to C7 level, with low signal intensity on T1 and T2 weighted images and non-enhancement on T1 weighted-enhanced images. We decided to undertake surgical exploration. At the operation field, there was yellow colored, thickened fibrous tissue over the dura mater. The lesion was removed totally, and decompression of spinal cord was achieved. Symptoms improved partially after the operation. Histopathologically, fibrotic pachymeninges with scanty inflammatory cells was revealed, which was compatible with diagnosis of idiopathic hypertrophic pachymeningitis. Six months after operation, motor power grade of both lower extremities was normal on physical examination. However, the patient still complained of mild weakness in the right lower extremity. Although the nature of IHSP is generally indolent, decompressive surgery should be considered for the patient with definite or progressive neurologic symptoms in order to prevent further deterioration. In addition, IHSP can present as an osteolytic lesion. Differential diagnosis with neoplastic disease, including giant cell tumor, is important.

A study on Design and Evaluation of The Continuous Flow Intersection (연속교차로의 설계 및 평가에 관한 연구)

  • 박창수
    • Journal of Korean Society of Transportation
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    • v.17 no.5
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    • pp.79-86
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    • 1999
  • Traffic jams of our country are due to the shortage of roadway as compared with the traffic, however. they are sometimes due to inconsistency of the roadway capacity. Inconsistency of the roadway capacity comes from the difference of cycle length, phase length and number of Phase between major intersection and minor intersection. Specialty increasing number of Phase due to left-turn movements bring out decrease of the arterial capacity, deterioration of the arterial offset. The Purpose of this research is to introduce and analyze the continuous flow intersection to solve the bottleneck of the major intersection. The major contents of this research introduce the concept and design consideration for the continuous flow intersection and also analyze delay, fuel consumption and emissions among multiphase intersection, grade separated intersection and continuous flow intersection. This research analyze the sensitivities according to change of the left-turn traffic volume and also evaluate the cost-effectiveness through the total cost analysis among three of them.

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Selection of Suitable Organic Matter for To-jik Nursery in Panax ginseng C.A. Meyer (인삼 재배 시 토직모 생산에 적합한 유기물 선발)

  • Kim, Dong-Won;Kim, Hee-Jun;Park, Jong-Suk;Kim, Dae-Hyang;Cheong, Seong-Soo;Ryu, Jeong
    • Korean Journal of Medicinal Crop Science
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    • v.18 no.2
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    • pp.74-78
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    • 2010
  • This experiment was carried out to select suitable organic matter in To-jik nursery (self soil nursery) for complement To-jik nursery's defects that are deterioration of raw material by poor quality of seed ginseng and reduction of the quantity in seed ginseng production. Organic matter used were Yacto, rice bean, defatted rice bran, soybean cake and their mixture. As follows, bulk density in soil physical property by treating organic composts was the greatest in soybean cake and the next was followed by mix, Yacto, defatted rice bran, and rice bran treatment in order. Soil pore space ratio was totally the opposite; that was rice bran the first and followed by defatted rice bran, Yacto, mix and soybean cake treatment. The incidence rate of damping off by treating organic composts was 1.5% in both soybean cake and mix while the others was 1.0%. Emergence time was the same among treatment on April 16 and Emergence rate was the highest at 73% in Yacto. There was no significant differences among treatment in the growth of aboveground part but it was a little better in defatted rice bran treatment. In Yacto treatment, the growth of underground part, total root number per kan, rate of first grade ginseng seedling, and rate of usable ginseng seedling etc. were entirely higher but there was little differences. Using defatted rice bran was slightly lower in productivity compared to Yacto, but the possibility was high as a alternative for Yacto in a view of managing cost down.

Processing and Quality of Natural-tasting Steamed Fish Paste Containing Unwashed Pufferfish Lagocephalus wheeleri Surimi (복어(Lagocephalus wheeleri) 수리미를 첨가한 어묵의 제조 및 품질특성)

  • Ahn, Byeong-Soo;Kim, Byeong-Gyun;Hwang, Seok-Min;Park, No-Hyun;Lee, Hyun-Jin;Oh, Kwang-Soo
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.52 no.6
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    • pp.562-570
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    • 2019
  • To develop natural-tasting fish paste from the pufferfish Lagocephalus wheeleri, steamed pufferfish paste (SPP) was prepared and its optimal processing conditions, quality metrics, and shelf-life characteristics were examined. SPP was produced by thawing golden threadfin Nemipterus virgatus surimi (FA grade), then adding 10% unwashed pufferfish surimi (PS), 1.5% salt, 8.0% wheat starch, 0.25% calcium carbonate, 0.25% sugar, 0.75% sorbitol, 0.25% polyphosphate, and 12.0% pufferfish hot-water extract (Brix 10°). The meat was ground with a Stephan mixer, molded at low temperature (18℃, 10 h), vacuum packed in a laminated plastic film bag, heat treated with hot water (95℃, 50 min), and cooled. As the amount of PS added increased, the whiteness, gel strength, and shear strength of the SPP decreased slightly. However, the SPP folding test showed no deterioration in the texture. In the sensory evaluation, the SPP received a higher rating for taste, smell, and overall taste than commercial Japanese pufferfish Kamaboko. The total amino acid content of the SPP was 10,262.6 mg/100 g; the major amino acids were aspartic acid, glutamic acid, alanine, valine, leucine, lysine, and arginine. The free amino acid content was 133.0 mg/100 g; the major amino acids were taurine, glutamic acid, glycine, alanine, cystine, and lysine.

Clinical Analysis of 21 Cases of Spinal Cord Ependymoma : Positive Clinical Results of Gross Total Resection

  • Kaner, Tuncay;Sasani, Mehdi;Oktenoglu, Tunc;Solmaz, Bilgehan;Sarioglu, Ali Celin;Ozer, Ali Fahir
    • Journal of Korean Neurosurgical Society
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    • v.47 no.2
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    • pp.102-106
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    • 2010
  • Objective : To evaluate the clinical results of gross total resection in the surgical approach to spinal ependymoma. Methods : Between June 1995 and May 2009,13 males and 8 females (mean age 34) diagnosed with intramedullary or extramedullary spinal ependymoma were surgically treated at our centre. The neurological and functional state of each patient were evaluated according to the modified McCormick scale. Results : The average follow-up duration was 54 months (ranging from 12 to 168 months). The locations of the lesions were : thoracic region (4, 19%), lumbar region (7, 34%), cervical region (4, 19%), cervicothoracic region (3, 14%) and conus medullaris (3, 14%). Four patients (19%) had deterioration of neurological function in the early postoperative period. The neurological function of three patients was completely recovered at the 6th postoperative month, while that of another patient was recovered at the 14th month. In the last assessment of neurological function, 20 patients (95%) were assessed as McCormick grade 1. No perioperative complications developed in any of our patients. In one patient's 24-month assessment, tumour recurrence was observed. Re-operation was not performed and the patient was taken under observation. Conclusion : Two determinants of good clinical results after spinal ependymoma surgery are a gross total resection of the tumour and a good neurological condition before the operation. Although neurological deficits in the early postoperative period can develop as a result of gross total tumour resection, significant improvement is observed six months after the operation.

Treatment outcome of radiation therapy and concurrent targeted molecular therapy in spinal metastasis from renal cell carcinoma

  • Park, Sangjoon;Kim, Kyung Hwan;Rhee, Woo Joong;Lee, Jeongshim;Cho, Yeona;Koom, Woong Sub
    • Radiation Oncology Journal
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    • v.34 no.2
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    • pp.128-134
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    • 2016
  • Purpose: To evaluate the clinical outcomes of patients who underwent radiation therapy with or without targeted molecular therapy for the treatment of spinal metastasis from renal cell carcinoma (RCC). Materials and Methods: A total of 28 spinal metastatic lesions from RCC patients treated with radiotherapy between June 2009 and June 2015 were retrospectively reviewed. Thirteen lesions were treated concurrently with targeted molecular therapy (concurrent group) and 15 lesions were not (nonconcurrent group). Local control was defined as lack of radiographically evident local progression and neurological deterioration. Results: At a median follow-up of 11 months (range, 2 to 58 months), the 1-year local progression-free rate (LPFR) was 67.0%. The patients with concurrent targeted molecular therapy showed significantly higher LPFR than those without (p = 0.019). After multivariate analysis, use of concurrent targeted molecular therapy showed a tendency towards improved LPFR (hazard ratio, 0.13; 95% confidence interval, 0.01 to 1.16). There was no difference in the incidence of systemic progression between concurrent and nonconcurrent groups. No grade ${\geq}2$ toxicities were observed during or after radiotherapy. Conclusion: Our study suggests the possibility that concurrent use of targeted molecular therapy during radiotherapy may improve LPFR. Further study with a large population is required to confirm these results.

Electrochemical Characteristics of Solid Polymer Electrode Fabricated with Low IrO2 Loading for Water Electrolysis

  • Ban, Hee-Jung;Kim, Min Young;Kim, Dahye;Lim, Jinsub;Kim, Tae Won;Jeong, Chaehwan;Kim, Yoong-Ahm;Kim, Ho-Sung
    • Journal of Electrochemical Science and Technology
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    • v.10 no.1
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    • pp.22-28
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    • 2019
  • To maximize the oxygen evolution reaction (OER) in the electrolysis of water, nano-grade $IrO_2$ powder with a low specific surface was prepared as a catalyst for a solid polymer electrolyte (SPE) system, and a membrane electrode assembly (MEA) was prepared with a catalyst loading as low as $2mg\;cm^{-2}$ or less. The $IrO_2$ catalyst was composed of heterogeneous particles with particle sizes ranging from 20 to 70 nm, having a specific surface area of $3.8m^2g^{-1}$. The anode catalyst layer of about $5{\mu}m$ thickness was coated on the membrane (Nafion 117) for the MEA by the decal method. Scanning electron microscopy (SEM) and electrochemical impedance spectroscopy (EIS) confirmed strong adhesion at the interface between the membrane and the catalyst electrode. Although the loading of the $IrO_2$ catalyst was as low as $1.1-1.7mg\;cm^{-2}$, the SPE cell delivered a voltage of 1.88-1.93 V at a current density of $1A\;cm^{-2}$ and operating temperature of $80^{\circ}C$. That is, it was observed that the over-potential of the cell for the oxygen evolution reaction (OER) decreased with increasing $IrO_2$ catalyst loading. The electrochemical stability of the MEA was investigated in the electrolysis of water at a current density of $1A\;cm^{-2}$ for a short time. A voltage of ~2.0 V was maintained without any remarkable deterioration of the MEA characteristics.

Characteristics and Management Plan of Water Quality at the Water Pollution Deterioration Area of the Upper Stream of Gapcheon (갑천 상류부의 수질오염 우려구간 수질특성 및 수질관리방안)

  • Jang, Yuho;Son, Bongho;Chu, Shaoxiong;Lim, Bongsu
    • Journal of Korean Society on Water Environment
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    • v.35 no.5
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    • pp.399-408
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    • 2019
  • The average annual water quality at Yongchon Bridge, Bonggok 2 Bridge, and Gasuwon Bridge in upstream of Gapcheon in 2018 was Ib grade (good) in organic matters, including BOD and TOC compared to the local environmental standard in Daejeon. However, their monthly changes for TOC partially exceeded the standard during the busy farming season at Bonggok 2 Bridge and Gasuwon Bridge. Although the annual average TP was within the standard, the monthly change at Bonggok 2 Bridge partially exceeded the standard. For Dugyecheon, the annual average water quality in 2018 at Umyeon-dong Bridge and Wonjeong Bridge, which are downstream of the Gyeryong public sewage treatment plant, exceeded the local environmental standard in BOD. COD was exceeded, and TP was within the standard. It seemed that the causes of deteriorated water quality downstream of Dugyecheon were discharges of agricultural water from agricultural land and effluent from the Gyeryong public sewage treatment plant. Assuming the pollution load of 100% based at the Mulangil point of the mainstream of Gapcheon, the ratio of BOD load and TOC load were as high as 58% and 47%, respectively. At the basin of Bonggok 2 Bridge and Mulangil, the loads downstream of Dugyecheon including the Gyeryong public sewage treatment plant were as high as 43% for TN and 56% for TP, respectively, indicating that Dugyecheon had a major impact on the water quality at the mainstream of Gapcheon.

A Case Report of Korean Medical Intervention in a Patient with Myasthenia Gravis after Myasthenia Crisis (근무력증 위기를 겪은 중증근무력증 환자의 한의학적 중재에 관한 증례보고 1례)

  • Kim, Yeseul;Park, Jiyoon;Min, Seonwoo;Moon, Jiseong;Hong, Junghwa;Ahn, Lib;Choi, Dongjun
    • The Journal of Internal Korean Medicine
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    • v.43 no.2
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    • pp.244-253
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    • 2022
  • Objective: This study reports on the management of a patient with myasthenia gravis (MG) following myasthenic crisis (MC) using Korean medicine. Methods: A 77-year-old Class V MG patient was treated with acupuncture, moxibustion, and Korean herbal medicine. A manual muscle test was used to derive a Medical Research Council (MRC) score and the patient's subjective view of his dyspnea was measured to assess MG symptoms. Results: The MRC grade indicated significant deterioration after 65 days of treatment, although there was no change in the patient's subjective dyspnea assessment. But no other MG or MC complications occurred. Conclusion: This study suggests that Korean medicine could be used for the management of Class V MG patients.

Characteristic of Current and Temperature according to Normal and Abnormal Operations at Induction Motor of 2.2 kW and 3.7 kW (2.2 kW와 3.7 kW 유도전동기의 정상과 구속운전에 따른 전류 및 온도 특성)

  • Jong-Chan Lee;Doo-Hyun Kim;Sung-Chul Kim
    • Journal of the Korean Society of Safety
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    • v.38 no.3
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    • pp.35-42
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    • 2023
  • This study analyzed the current and temperature characteristics of major components of an induction motor during normal and abnormal operations as functions of the difference in the rated capacities of medium and large-sized motors widely used in industrial settings. The temperature rise equation of the induction motor winding was derived through locked-rotor operation experiments and linear regression analysis. When the ambient temperature is 40 ℃, the time to reach 155 ℃, the temperature limit of the insulation class (F class) of the winding of the induction motor, was confirmed to be 48 seconds for the 2.2 kW induction motor and 39 seconds for the 3.7 kW induction motor. This means that when the rated capacity is large or the installation environment is high temperature, the time to reach the temperature limit of the insulation class during locked-rotor operation is short, and the risk of insulation deterioration and fire is high. In addition, even if the EOCR (Electronic Over Current Relay) is installed, if the setting time is excessively set, the EOCR does not operate even if the normal and locked-rotor operation of the induction motor is repeated, and the temperature limit of the insulation grade of the winding of the induction motor is exceeded. The results of this study can be used for preventive measures such as the promotion of electrical and mechanical measures for the failure of induction motors and fire prevention in industrial sites, or the installation of fire alarm systems.