• The Journal of the Korea Contents Association
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• v.11 no.12
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• pp.162-170
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• 2011

Through this thesis, I intended to analyze Hollywood animation through that achieved in box office by directing viewpoint. of Chris Sanders and Dean Deblois not only shows standard narrative structure of adventure, comedy, fantasy, but also express message of story and thorough visual. Analysis of directing classify contents and form. In contents, constitution of narrative and set up of character, irony of plot, characterization and popularity are embossed. In form, lighting and special effect, design and layout, 3D technology and stereoscopic camera technique based on the capital strength are outstanding. The high evaluation for film is possessed of box offic, remained within value and popularity, and delivered metaphysical theme without repulsion. The director's direction make success even if the pre-production manage by huge system approach.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.2
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• pp.867-872
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• 2016

Background: Esophageal cancer is one of the most serious malignancies. Due to the aggressive nature of this cancer, the prognosis is poor. A network meta-analysis with simultaneous comparison of multiple treatments can help determine better treatment options that have higher effects on overall survival of patients with lower adverse events. The aim of this review is to simultaneously compare efficacy and adverse events of treatment interventions for esophageal cancer. Materials and Methods: In this review, only randomized control trials (RCT) will be considered for network meta-analysis. All international electronic databases including Medline, Web of Sciences, Scopus, Cochran's library, EMBASE and Cancerlit will be searched to find randomized control trials which compared two or more treatment interventions for esophageal cancer. A network plot will be drawn for visual representation of all available treatment interventions. Bayesian approach will be used to combine the direct and indirect evidence. Treatment effects (e.g. hazard ratio for time to event outcomes, risk ratio for binary outcomes, and rate ratio for count outcomes with 95% credible interval) will be reported. Moreover, cumulative probability of the treatment ranks will be reported using the surface under the cumulative ranking (SUCRA) graphs. Consistency assumption will be assessed by the loop-specific and design-by-treatment interaction approaches. Conclusions: The results of this study may be helpful for the patients, clinicians and health policy makers in selecting treatments that have the best effect on survival and lowest adverse events.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.16
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• pp.6863-6869
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• 2014

Objectives: Several preclinical and observational studies have shown that anti-diabetic medications (ADMs) may modify the risk of lung cancer. We performed a systematic review and meta-analysis evaluating the effect of metformin, sulfonylureas (SUs), thiazolidinediones (TZDs), and insulin on the risk of lung cancer in patients with diabetes mellitus (DM). Materials and Methods: We conducted a systematic search of Pubmed and Web of Science, up to August 20, 2013. We also searched the Conference Proceedings Citation Index (CPCI) and China National Knowledge Infrastructure (CNKI) for abstracts from major meetings. Fixed or random effect pooled measures were selected based on heterogeneity among studies, which was evaluated using Q test and the I2 of Higgins and Thompson. Meta-regression was used to explore the sources of between-study heterogeneity. Publication bias was analyzed by Begg's funnel plot and Egger's regression test. Associations were assessed by odds ratios (ORs) with 95% confidence intervals (CIs). Results: A total of 15 studies (11 cohort, 4 case-control) were included in this meta-analysis. In observational studies no significant association between metformin (n=11 studies; adjusted OR=0.99, 95%CI: 0.87-1.12), SUs (n=5 studies; adjusted OR=0.98, 95%CI: 0.79-1.22), or TZDs (n=7 studies; adjusted OR=0.92, 95%CI: 0.75-1.13), insulin (n=6 studies; adjusted OR=1.13, 95%CI: 0.79-1.62) use and risk of developing lung cancer was noted. There was considerable inherent heterogeneity between studies not explained by study design, setting, or location. Conclusions: Meta-analysis of existing studies does not support a protective or harmful association between ADMs use and risk of lung cancer in patients with DM. There was considerable heterogeneity across studies, and future, well-designed, prospective studies would be required for better understanding of any association.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.12
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• pp.7473-7482
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• 2013

The G-protein coupled receptor 87 (GPR87) is a recently discovered orphan GPCR which means that the search of their endogenous ligands has been a novel challenge. GPR87 has been shown to be overexpressed in squamous cell carcinomas (SCCs) or adenocarcinomas in lungs and bladder. The 3D structure of GPR87 was here modeled using two templates (2VT4 and 2ZIY) by a threading method. Functional assignment of GPR87 by SVM revealed that along with transporter activity, various novel functions were predicted. The 3D structure was further validated by comparison with structural features of the templates through Verify-3D, ProSA and ERRAT for determining correct stereochemical parameters. The resulting model was evaluated by Ramachandran plot and good 3D structure compatibility was evidenced by DOPE score. Molecular dynamics simulation and solvation of protein were studied through explicit spherical boundaries with a harmonic restraint membrane water system. A DRY-motif (Asp-Arg-Tyr sequence) was found at the end of transmembrane helix3, where GPCR binds and thus activation of signals is transduced. In a search for better inhibitors of GPR87, in silico modification of some substrate ligands was carried out to form polar interactions with Arg115 and Lys296. Thus, this study provides early insights into the structure of a major drug target for SCCs.

• Cartoon and Animation Studies
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• s.47
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• pp.149-170
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• 2017

which was first shown as TV series in 1995 has been highly praised until now successful animation that reflected human psychology and ideology. first gained popularity in Japan and spreaded into global animation market. Characteristics of can be summarized as mechanical design, realistic military mise-en-scene, and philosophical view of the world based on the bible. All works reflect the philosophy and ideology of the writer/creator, but reflects various form of ideology. Furthermore, 's ambiguous and vague plot made the fans to discuss and analyze about the work, which brought secondary marketing effect. In this report, the ideology reflected in will be analyzed and understand how these ideologies were reflected in the work. By analyzing religious, psychological and philosophy ideologies in , ideology can be proved as success factor of animation films.

• Korean Journal of Soil Science and Fertilizer
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• v.44 no.1
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• pp.91-97
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• 2011

The objectives of this research were to investigate the system of rice intensification (SRI) on early growth, grain yield, and yield components under Chinese milk vetch residue-mulched no-tillage cropping systems at silt loam soil. The field was prepared as a split-plot design with three replications, main plots consisted of Dongjinbyeo, and Sobibyeo as a cultivar, and subplots consisted of $10{\times}10$ cm, $20{\times}20$ cm, and $30{\times}30$ cm as a planting density. Weed infestation during rice growing season was more severe in wider planting density $30{\times}30$ at 35 days after transplanting (DAT), and $20{\times}20$ cm at 95 DAT in both Sobibyeo and Dongjinbyeo. The maximum plant height was recorded in Sobibyeo compared with Dongjinbyeo, $10{\times}10$ cm and $20{\times}20$ cm planting density compared with $30{\times}30$ cm from 20 DAT until 60 DAT. Among the three planting densities, SPAD values were significantly greater in planting density of $20{\times}20$ cm both in Sobibyeo and Dongjinbyeo followed by $30{\times}30$ cm compared with closer planting density of $10{\times}10$ cm. The lowest grain yield was observed in wider planting density of $30{\times}30$ in both Sobibyeo and Dongjinbyeo due to lower number of panicle per unit area. Our findings suggest that optimum planting density for SRI in no-tillage paddy was $20{\times}20$ cm and it should be useful the systems to small-scale rice farmers in Korea as a sustainable farming system.

• Korean journal of communication and information
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• v.32
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• pp.7-48
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• 2006

The study explores how Korea's major newspaper cover about science news, especially how newspaper frame biotechnology news including new source, news construction ways, coverage trend. The research has a research design to find out coverage pattern or model with frame theory. The result shows that the newspaper has some aspect of frame through out the biotechnology development in the section, theme, source, complexity. The section has been expend to the society and international section, while the theme shift from disease or cancer cure to life itself, genome, or stem cell. In the complexity, the biotechnology news stories have been developed a story plot (event-problem-development-solution). In the climax, the news coverage focuses on the explanation of biotechnology news.

• Journal of the Korean Electrochemical Society
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• v.12 no.1
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• pp.11-25
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• 2009

Fuel cells are expected to be one of the major clean new energy sources in the near future. However, the slow kinetics of electrocatalytic hydrogen oxidation reaction (HOR) and oxygen reduction reaction (ORR), and the high loading of Pt for the anode and cathode material are the urgent issues to be addressed since they determine the efficiency and the cost of this energy source. In this review paper, a new approach was developed for designing electrocatalysts for the HOR and ORR in fuel cells. It was found that the electronic properties of Pt could be fine-tuned by the electronic and geometric effects introduced by the substrate alloy metal and the lateral effects of the neighboring metal atoms. The role of substrate was found reflected in a volcano plot for the HOR and ORR as a function of their calculated d-band centers. This paper demonstrated a viable way to designing the electrocatalysts which could successfully alleviate two issue facing the commercializing of the fuel cell-the cost of electrocatalysts and their efficiency.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.14 no.5
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• pp.42-49
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• 2015

In this study, the multi-disk of a high-pressure drop control valve is designed and manufactured. Then, the flow rate and high-pressure drop of fluids flowing in the high-pressure drop control valve is CAE/CFD. This study involves numerical analysis for the Zambil offshore project of a high-pressure drop control valve. ANSYS used a solver for offshore structures analysis. A high-pressure drop control valve, which transforms the power transfer of a system by reducing the inlet pressure of 345bar to the outlet pressure of 112bar, is a fundamental component in the offshore process. This study not only analyzes the relation between pressure drop and fluid velocity in a trim by using fluid analysis, but also examines the possibility of cavitation in a valve in addition to the plot for the extension of lifespan. It is demonstrated that the pressure drop from 345bar to 112bar is more feasible in the presence of the trim, which can induce a continuous and diminutive pressure drop in order to prevent cavitation in a high-pressure drop control valve.

• Asian-Australasian Journal of Animal Sciences
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• v.13 no.5
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• pp.630-635
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• 2000

Previous research has not evaluated the effects of various rates and frequencies of manure application and frequencies of cutting on yield and stand persistence of cool-season grasses and alfalfa-grass mixtures. The primary objective of this study was to compare the effects of cutting management systems on herbage yield and stand persistence of orchardgrass (Dactylis glomerata L.) and an alfalfa (Medicago sativa L.)-orchardgrass mixture from various rates and frequencies of dairy slurry application. A randomized complete block design with treatments in a sub-subplot arrangement with four replicates was used. The main plot consisted of 2 cutting management systems (4 and 5 annual cuttings). The subplots were 9 fertility treatments: 7 slurry rate and frequency of application treatments, one inorganic fertilizer treatment, and an unfertilized control. The split-split-plots were the two forage species: orchardgrass and alfalfa-orchardgrass mixture. The study was initiated after 1st cutting in 1995. Cumulative yields of the 2nd and subsequent cuttings of both orchardgrass and alfalfa-orchardgrass in 1995 were higher for the 5-cutting system than the 4-cutting system. The 1995 growing season was abnormally dry. In 1996, an abnormally wet year, the reverse was true, total herbage yields being higher for the 4-cutting system than the 5-cutting system. Species response to fertility rate/frequency treatments was different in both years. Higher application rates early in the season and carryover of nutrients from late season applications the previous year appear to be responsible for the yield increases of those fertility treatments having significant yield differences between the cutting management systems. The stand ratings of orchardgrass were not affected by cutting management. In the spring of 1997, however, the stand ratings of alfalfa-orchardgrass in the 4-cutting management system were significantly greater than the 5-cutting management system. The very high manure application rate significantly reduced the stand ratings of alfalfa-orchardgrass in the 5-cutting system.