• 제목/요약/키워드: design guide

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Key success factors for implementing modular integrated construction projects - A literature mining approach

  • Wuni, Ibrahim Yahaya;Shen, Geoffrey Qiping
    • 국제학술발표논문집
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    • The 8th International Conference on Construction Engineering and Project Management
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    • pp.343-352
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    • 2020
  • Modular integrated construction (MiC) is an innovative construction method where components of a building are manufactured in an offsite factory, trucked to the job site in sections, set in place with cranes, and assembled together to form a whole building. Where circumstances merit, favorable conditions exist and implemented effectively; MiC improves project performance. However, several key factors need to converge during implementation to realize the full benefits of MiC. Thus, a thorough understanding of the factors which are critical to the success of MiC projects is imperative. Drawing on a systematic review of 47 empirical studies, this research identified 25 key success factors (KSFs) for MiC projects. Of these, the five topmost cited KSFs for MiC projects include effective working collaboration and communication among project participants; standardization, optimization, automation and benchmarking of best practices; effective supply chain management; early design freeze and completion; and efficient procurement method and contracting. The study further proposed a conceptual model of the KSFs, highlighting the interdependences of people, processes, and technology-related KSFs for the effective accomplishment of MiC projects. The set of KSFs is practically relevant as they constitute a checklist of items for management to address and deal with during the planning and execution of MiC projects. They also provide a useful basis for future empirical studies tailored towards measuring the performance and success of MiC projects. MiC project participants and stakeholders will find this research useful in reducing failure risks and achieving more desired performance outcomes. One potential impact of the study is that it may inform, guide, and improve the successful implementation of MiC projects in the construction industry. However, the rigor of the analysis and relative importance ranking of the KSFs were limited due to the absence of data.

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Chemoquiescence with Molecular Targeted Ablation of Cancer Stem Cells in Gastrointestinal Cancers

  • Jong-Min Park;Young-Min Han;Migyeong Jeong;Eun Jin Go;Napapan Kangwan;Woo Sung Kim;Ki Baik Hahm
    • Journal of Digestive Cancer Research
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    • 제4권1호
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    • pp.1-9
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    • 2016
  • The abundance of multi-drug resistance ATPase binding cassette and deranged self-renewal pathways shown in cancer stem cells (CSCs) played a crucial role in tumorigenesis, tumor resistance, tumor recurrence, and tumor metastasis. Therefore, elucidation of CSCs biology can improve diagnosis, enable targeted treatment, and guide the follow up of GI cancer patients. In order to achieve chemoquiescence, seizing cancer through complete ablation of CSCs, CSCs are rational targets for the design of interventions that will enhance responsiveness to traditional therapeutic strategies and contribute in the prevention of local recurrence as well as metastasis. However, current cancer treatment strategies fail to either detect or differentiate the CSCs from their non-tumorigenic progenies mostly due to the absence of specific biomarkers and potent agents to kill CSCs. Recent advances in knowledge of CSCs enable to produce several candidates to ablate CSCs in gastrointestinal (GI) cancers, especially cancers originated from inflammation-driven mutagenesis such as Barrett's esophagus (BE), Helicobacter pylori-associated gastric cancer, and colitis-associated cancer (CAC). Our research teams elucidated through revisiting old drugs that proton pump inhibitor (PPI) and potassium competitive acid blocker (p-CAB) beyond authentic acid suppression, chloroquine for autophage inhibition, sonic hedgehog (SHH) inhibitors, and Wnt/β-catenin/NOTCH inhibitor can ablate CSCs specifically and efficiently. Furthermore, nanoformulations of these molecules could provide an additional advantage for more selective targeting of the pathways existing in CSCs just like current molecular targeted therapeutics and sustained action, while normal stem cells intact. In this review article, the novel approach specifically to ablate CSCs existing in GI cancers will be introduced with the introduction of explored mode of action.

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하브루타 교수법을 적용한 여성건강간호학 수업이 간호학생의 자기주도적 학습능력, 비판적 사고성향 및 학습몰입에 미치는 효과 (The effects of self-directed learning ability, critical thinking, and learning commitment from utilizing the Havruta method in women's health nursing classes)

  • 양정하;정미영
    • 한국간호교육학회지
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    • 제29권4호
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    • pp.352-361
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    • 2023
  • Purpose: The purpose of this study was to construct the education applying the Havruta method for nursing students and to investigate the effects on self-directed learning ability, critical thinking, and learning commitment. Methods: A nonequivalent control group pre-posttest design was used. The participants were 63 nursing students (experimental group, n=31; control group, n=32) at two universities. The experimental group received education applying the Havruta method for five weeks. The study was conducted from September 1 to November 30, 2022. The data were analyzed using IBM SPSS 27.0 for an χ2 test, Fisher's exact test, independent t-test, and Mann-Whitney U-test. Results: The experimental group had a significant increase in self-directed learning ability (z=-2.13, p=.033). However, there was no significant difference in critical thinking competency (t=0.64, p=.524) and learning commitment (t=0.04, p=.969) between the two groups. Conclusion: The Havruta method is an effective nursing education tool for self-directed learning ability. The result of this study could be a guide for nursing professors in designing and implementing educational programs that apply the Havruta method. In the future, research that applies the Havruta method and evaluates its effectiveness in nursing education programs should be continued.

수치해석을 통한 암성토 부분보강의 침하억제 효과 평가 (Numerical Evaluation of Settlement Reducing Effect by Partial Reinforcement of Rock Fill)

  • 이수형;최영태;한진규;구교영
    • 한국지반공학회논문집
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    • 제39권11호
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    • pp.23-31
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    • 2023
  • 콘크리트 궤도의 침하는 고속열차의 안전한 운행을 크게 저해할 수 있으며 복구에 상당한 비용이 소요되므로 최근 큰 문제로 대두되고 있다. 침하의 가장 큰 원인 중 하나는 터널공사의 부산물로 발생하는 암석재료를 적정한 입도분를 가진 토사 혼합 없이 하부노반 성토에 사용하기 때문으로 보고되고 있다. 본 논문에서는 암석재료로 성토된 하부노반의 부분 보강으로 인한 침하억제 효과를 수치해석으로 평가하였다. 하부노반에 일정하게 배치된 기둥 형태의 보강 영역은 상부노반에 지반아칭을 유발하게 되며 성토하중이 보강된 영역에 집중하게 되어 침하가 억제되는 효과가 있다. 유한요소해석을 통하여 보강된 영역의 크기, 강성, 간격이 하부노반의 침하억제에 미치는 효과를 평가하였으며, 해석 결과를 토대로 침하를 허용치 이내로 억제하기 위한 최소 보강 간격을 결정하는 설계 방법을 제안하였다.

Effects of different feeding systems on ruminal fermentation, digestibility, methane emissions, and microbiota of Hanwoo steers

  • Seul Lee;Jungeun Kim;Youlchang Baek;Pilnam Seong;Jaeyong Song;Minseok Kim;Seungha Kang
    • Journal of Animal Science and Technology
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    • 제65권6호
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    • pp.1270-1289
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    • 2023
  • This study evaluates how different feeding systems impact ruminal fermentation, methane production, and microbiota of Hanwoo steers native to Korea. In a replicated 2 × 2 crossover design over 29 days per period, eight Hanwoo steers (507.1 ± 67.4 kg) were fed twice daily using a separate feeding (SF) system comprising separate concentrate mix and forage or total mixed rations (TMR) in a 15:85 ratio. The TMR-feeding group exhibited a considerable neutral detergent fiber digestibility increase than the SF group. However, ruminal fermentation parameters and methane production did not differ between two feeding strategies. In addition, TMR-fed steers expressed elevated Prevotellaceae family, Christensenellaceae R-7 group, and an unidentified Veillonellaceae family genus abundance in their rumen, whereas SF-fed steers were rich in the Rikenellaceae RC9 gut group, Erysipelotrichaceae UCG-004, and Succinivibrio. Through linear regression modeling, positive correlations were observed between the Shannon Diversity Index and the SF group's dry matter intake and methane production. Although feeding systems do not affect methane production, they can alter ruminal microbes. These results may guide future feeding system investigations or ruminal microbiota manipulations as a methane-mitigation practice examining different feed ingredients.

무인항공기의 자동 착륙을 위한 LSM 및 CPA를 활용한 영상 기반 장애물 상태 추정 및 충돌 예측 (Vision-based Obstacle State Estimation and Collision Prediction using LSM and CPA for UAV Autonomous Landing)

  • 이성봉;박천만;김혜지;이동진
    • 한국항행학회논문지
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    • 제25권6호
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    • pp.485-492
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    • 2021
  • 무인항공기의 영상 기반 자동 정밀 착륙 기술은 착륙 지점에 대한 정밀한 위치 추정 기술과 착륙 유도 기술이 요구된다. 또한, 안전한 착륙을 위하여 지상 장애물에 대한 착륙 지점의 안전성을 판단하고, 안전성이 확보된 경우에만 착륙을 유도하도록 설계되어야 한다. 본 논문은 자동 정밀 착륙을 수행하기 위하여 영상 기반의 항법과 착륙 지점의 안전성을 판단하기 위한 알고리즘을 제안한다. 영상 기반 항법을 수행하기 위해 CNN 기법을 활용하여 착륙 패드를 탐지하고, 탐지 정보를 활용하여 통합 항법 해를 도출한다. 또한, 위치 추정 성능을 향상시키기 위한 칼만필터를 설계 및 적용한다. 착륙 지점의 안전성을 판단하기 위하여 동일한 방식으로 장애물 탐지 및 위치 추정을 수행하고, LSM을 활용하여 장애물의 속도를 추정한다. 추정한 장애물의 상태를 활용하여 계산한 CPA를 기반으로 장애물과의 충돌 여부를 판단한다. 최종적으로 본 논문에서 제안된 알고리즘을 비행 실험을 통해 검증한다.

관광가이드의 긍정심리자본 요인이 직무만족 및 조직몰입에 미치는 영향에 관한 연구 (A Study on the Impact Positive Psychological Capital of Tour Guides on Job Satisfaction and Organizational Commitment )

  • 양성호;최재우
    • 아태비즈니스연구
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    • 제14권2호
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    • pp.167-185
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    • 2023
  • Purpose - The purpose of this study is to identify the influence relationship between positive psychological capital, job satisfaction, and organizational commitment of tourism guides, and to provide implications through empirical research to increase the capabilities of tourism guides that are a factor in the performance of planned travel products Design/methodology/approach - This study conducted an empirical survey using the google online questionnaire. It was directly surveyed, distributed, and collected from workers who were or were performing tourism guide duties in Asia and Europe, and 203 questionnaires were used for analysis. The empirical survey was conducted in a self-written manner through a simple random sampling method, and the statistical package was conducted with frequency analysis, factor analysis, multiple regression analysis, and correlation analysis using the spss 21.0 program. Findings - First, among the positive psychological capital factors, two factors, hope and optimism, have a significant positive (+) effect on job satisfaction. Second, among the positive psychological capital factors, two factors, self-efficacy and optimism, have a significant positive (+) effect on organizational commitment. Third, job satisfaction has a significant positive (+) effect on organizational commitment Research implications or Originality - The implications of this study are that the research results have had a positive (+) effect on the variables of positive psychological capital, job satisfaction, and organizational commitment of tourism guides, and have laid the foundation for academic research on research topics. In practice, it is expected to increase the positive psychological capital of tourism guides and have a significant impact on the organization's performance by actively supporting and supporting individuals related to the sustainable growth of travel products.

기업의 사회적 책임(CSR) 활동이 혁신성과에 미치는 영향: 지식공유와 혁신행동의 직렬이중매개효과 (The Effect of Corporate Social Responsibility(CSR) Activities on Innovation Performance: The Sequential Mediation Effect of Knowledge Sharing and Innovation Behavior)

  • 뤼양;진춘화
    • 아태비즈니스연구
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    • 제14권2호
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    • pp.63-84
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    • 2023
  • Purpose - The purpose of this study is to examine the effect of CSR activities on innovation performance and to identify the mediating role of knowledge sharing and innovation behaviors between CSR activities and innovation performance. In addition, the purpose of this study is to verify the role of sequential mediating effect of knowledge sharing and innovation behavior between CSR activities and innovation performance. Design/methodology/approach - This study collected survey data from 293 organizational members working in Chinese companies. The exploratory factor analysis (EFA), confirmatory factor analysis (CFA), reliability analysis, correlation analysis and process macro were used in order to analyze the data. Findings - First, this study verified that CSR activities had a significant positive effect on knowledge sharing, innovation behavior, and innovation performance. Second, it was found that knowledge sharing had a significant positive effect on innovation behavior and innovation performance. Third, it was verified that innovation behavior had a significant positive effect on innovation performance. Fourth, knowledge sharing and innovation behavior had a sequential mediating effect in the relationship between CSR activities and innovation performance. Research implications or Originality - With the uncertainty of the environment and the intensification of competition among companies, more and more companies begin to pay attention to innovation. Different from existing studies, this study focuses on CSR activities, identifies the role of CSR activities, explores ways to guide innovation performance, and verifies the sequential mediating role of knowledge sharing and innovation behavior. Through this measure, the importance of knowledge sharing and innovative behavior among organizational members is emphasized, solutions to strengthen innovation are explored, and theoretical and practical implications are provided for companies.

양면 마이크로 패턴 차량용 후육 라이트 가이드의 사출성형 패턴 전사성에 관한 연구 (Study of injection molded pattern transferability of double-sided micro-patterned automotive thick light guides)

  • 이동원;김상윤;김지우;김종수;이성희
    • Design & Manufacturing
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    • 제17권4호
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    • pp.42-51
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    • 2023
  • In this study, we investigated the injection molding technology of thick-walled light guides, which are parts that control the light source of automotive lamps. Through injection molding analysis, the gate position that can minimize product shrinkage and deformation was selected, and a mold reflecting the analysis results was manufactured to evaluate the effect of injection speed and holding pressure on transferability during micro-pattern molding through experiments. When designing an injection mold for products with varying thicknesses, it was found that installing the gate on the side of the thicker part was advantageous for reducing volume shrinkage and deformation. It was found that the effect of shrinkage due to thickness may be greater than the position of the gate on pattern transferability. The pattern transfer error decreased as the injection speed and holding pressure increased, and it was found that increasing the injection speed was relatively effective.

생성형 인공지능 초기 단계의 사용자경험(UX): Q-방법론을 통해 살펴본 30-40대 직장인의 편의와 우려 (User Experience (UX) in the Early Days of Generative AI : The benefits and concerns of employees in their 30s and 40s through the Q-methodology)

  • 이은주;윤지찬;이준식;박도형
    • 한국정보시스템학회지:정보시스템연구
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    • 제33권1호
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    • pp.1-30
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    • 2024
  • Purpose The purpose of this study is to examine the customer experience of generative AI among office workers aged 30 to 40, investigating usability, usefulness, and affect, and understanding concerns and expectations. Design/Methodology/Approach This research used Q methodology to assess the customer experience of generative AI. Users are engaged in a problem-solving journey, and data is collected by having participants rank 36 statements based on usability, usefulness, and affect, referred to as the three goals of User Experience. Participants use a forced distribution table with a scale from -5 to +5 to indicate the subjective importance of each statement. The results identified four groups, reflecting different perspectives and attitudes toward generative AI. Findings Participants express overall comfort with generative AI, perceive AI as more knowledgeable in unfamiliar domains, but harbor doubts about AI's understanding. Disagreements emerge on AI replacing humans, the value of unique human roles, data confidentiality, fears of AI advancement, and emotional impacts. Identified four groups: Users who treat AI as a soulless assistant and are active in business use, Uncle users who want to use new technologies properly and are not afraid of technology, users who recognize the limits of AI despite its efficiency, and users who require strong verification in the future. It has the potential to guide future guidelines, ethical codes, and regulations for the appropriate use of AI. In addition, this approach lays the groundwork for future empirical analyses of generative AI.