• The Journal of Korean Academy of Prosthodontics
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• v.30 no.3
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• pp.361-378
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• 1992

The purpose of this investigation was to evaluate the effect of the porous hydroxyapatite particles (Interpore $200^{(R)}$) and guided tissue regeneration membrane ($Gore-Tex^{TM}$ augmentation material) on amount and shape of generating new bone adjacent to implant. Implants were placed immediately after extraction in the bilateral 3rd, 4th premolars of the mandible of the adult dogs. In all experimental groups, artificial bony defects were formed at the buccal cortex area, 3.3mm in width and 3.0mm in depth. In the control group : sutured without HA particles & membranes after placing implants, the experimental group 1 : membrane was place over the artificial bony defect, the experimental group 2 : bony defect was filled with HA particles and covered with membrane. The examination of bone-implant interfaces using light microscope and fluorescent microscope concluded as follows. 1. In all three experimental groups, osseointegration was observed without epithelial migration. 2. In the healing degree of bony defect area, the experimental group 1, 2 showed more prominent healing than control group, and the experimental group 1 showed the most excellent bone formation. 3. In fluorescent microscopic finding, bone remodeling was observed in regenerated bone tissue at defect area of experimental group 1, but in experimental group 2, irregular, discontinuous linear fluorescence was observed at the lower portion of defect area and sign of bone remodeling was weak.

• 한국신재생에너지학회:학술대회논문집
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• 2006.06a
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• pp.407-409
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• 2006

Geochemical analyses carried out on samples collected from cores on and near the southern smit of Hydrate Ridge have advanced understanding by providing a clear contrast of the two major modes of marine gas hydrate occurrence. High concentrations (15%-40% of pore space) of gas hydrate occurring at shallow depths (0-40 mbsf) on and near the southern summit are fed by gas migrating from depths of as much as 2km within the accretionary prism. This gas carries a characteristic minor component of C2-C5 thermogenic hydrocarbons that enable tracing of migration pathways and may stabilize the occurrence of some structure II gas hydrate. A structure II wet gas hydrate that is stable to greater depths and temperatures than structure I methane hydrate may account for the deeper, faint second bottom simulating reflection (BSR2) that occurs on the seaward side of the ridge. The wet gas is migrating In an ash/turbidite layer that intersects the base of gas hydrate stability on the seaward side of and directly beneath the southern summit of Hydrate Ridge. The high gas saturation (>65%) of the pore space within this layer could create a two-phase (gas + solid) system that would enable free gas to move vertically upward through the gas hydrate stability zone. Away from the summit of the ridge there is no apparent influx of the gas seeping from depth and sediments are characterized by the normal sequence of early diagenetic processes involving anaerobic oxidation of sedimentary organic matter, initially linked to the reduction of sulfate and later continued by means of carbonate reduction leading to the formation of microbial methane.

• Journal of the Korean Geotechnical Society
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• v.35 no.8
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• pp.5-15
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• 2019

This study was conducted to propose a reasonable requirement regulation of cutoff barriers composed of bottom layer and vertical barrier of offshore landfill for the prevention of contaminant leakage. The bottom layer was composed of impermeable clay layer; vertical walls were composed of double walls; outer wall was composed of steel sheet pile which registed against outer force; cutoff vertical barrier took the role of inner wall. Seepage-advection-dispersion numerical analysis was conducted using SEEP/W and CTRAN/W programs under steady and unsteady flows. The results showed that the values calculated under steady flow showed higher migration of pollutant than those of unsteady flow. The values calculated under steady flow are more valid from a design point of view. Under steady flow and the bottom clay layer and when the vertical barrier are homogeneous and completely well installed, respectively, the minimum required cutoff regulations for hydraulic conductivity, thickness, and embedded depth of the bottom clay layer and vertical barrier were suggested.

• Journal of Gastric Cancer
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• v.19 no.3
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• pp.315-328
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• 2019

Purpose: To investigate the clinical value of serum miR-221-3p and miR-122-5p expression levels in the diagnosis and prognosis of gastric cancer. Materials and Methods: Serum samples from 141 gastric cancer cases (gastric cancer group), 110 gastric polyps (gastric polyp group), and 75 healthy people (healthy control) were used to detect miR-221-3p and miR-122-5p expression using real-time reverse transcription polymerase chain reaction. Results: Serum miR-221-3p expression was significantly higher in the gastric cancer group than in the gastric polyp group, and it was significantly lower than that before operation. The miR-221-3p expression was significantly higher in the death group than in the survival group. The proliferation and migration ability significantly increased and the apoptosis rate significantly decreased by miR-221-3p transfection in gastric cancer cells. In contrast, the function of miR-122-5p in gastric cancer cells was opposite of miR-221-3p. Serum miR-221-3p expression was negatively correlated with that of miR-122-5p in gastric cancer. Serum miR-221-3p and miR-122-5p expressions were significantly correlated with the degree of differentiation, tumor, node, metastasis stage, lymph node metastasis, and invasion depth. miR-221-3p and miR-122-5p expression levels were independent prognostic factors for postoperative gastric cancer. In the diagnosis and predicting prognosis of gastric cancer, receiver operating characteristic analysis revealed that the area under curve of combined detection of serum miR-221-3p and miR-122-5p expression had a greater diagnostic effect than either single maker. Conclusions: The miR-221-3p and miR-122-5p are involved in the development of gastric cancer, and they have important clinical values in gastric cancer diagnosis and prognosis.

• Journal of Coastal Disaster Prevention
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• v.4 no.1
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• pp.7-19
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• 2017

In this study, waves and currents observed by acoustic AWAC, VECTOR and Aquadopp Profiler in Anmok coastal waters were analysed to account for the variability of wave and current and to understand the mechanism of sediment transport generated by wave-induced current in the surf-zone. The monthly variation of wave and residual currents were analysed and processed with long-term observed AWAC data at station W1, located at the water depth of about 18m measured during from February 2015 to September 2016. Wave-induced currents were also analysed with intensive field measurements such as wave, current, suspended sediment, and bathymetry data observed at the surf-zone during in winter and summer. The statistical result of wave data shows that high waves coming from NNE and NE in winter (DEC-FEB) are dominant due to strong winds from NE. But in the other season waves coming from NE and ENE are prevalent due to the seasonal winds from E and SE. The residual currents with southeastern direction parallel to the shoreline are dominant throughout a year except in winter showing in opposite direction. The speed of ebb-dominant southeastern residual currents decreasing from surface to the bottom is strong in summer and fall but weak in winter and spring. By analysing wave-induced current, we found that cross-shore current were generated by swell waves mainly in winter with incoming wave direction about $45^{\circ}$ normal to the shoreline. Depending on the direction of incoming waves, longshore currents in the surf-zone were separated to southeastern and northwestern flows in winter and summer respectively. The variation of observed currents near crescentic bars in the surf-zone shows different direction of longshore and cross-shore currents depending on incoming waves implying to the reason of beach erosion generating the beach cusp and sandbar migration during high waves at Anmok.

• Journal of The Geomorphological Association of Korea
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• v.25 no.2
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• pp.15-29
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• 2018

The sediment transport process in a river reflects the process of geomorphological change in the watershed, influencesthe river bed variation and the river channel migration, and is a parametric phenomenon that exhibits a dynamic self-adjusting process. Sediment load is divided into bedload and suspended load depending on the dominant mechanism. Quantitative sediment load is important information for solving river problems. Because it is difficult and time consuming to measure bedload, compared to that ofsuspended load, data on the sediment transport load and the research required for the gravel-bed rivers are insufficient. This study is to analyze the ratio of the bedload to the total sediment load in gravel-bed rivers. The sediment load ratio in gravel-bed rivers increases with the flow rate per unit width, and the rate of the bedload varies more rapidly than the suspended load. The sediment transport efficiency coefficient has been affected by the ratio of the flow depth to the mean diameter of particles and has been dependent on the shear velocity Reynolds number. So $A^{\ast}$ and $B^{\ast}$ are introduced to compensate for the uncertainties such as bed materials, sediment transport, and flow velocity distribution, and the coefficient of bedload ratio has been presented. For the sediment load data in experimental channels and rivers, A* was 3.1. The dominant variables of $B^{\ast}$ were $u_*d_m/{\nu}$ in the gravel-bed and h/dm in the sand-bed. When $B^{\ast}$ the is the same, in the experimental channels the coefficient of bedload ratio was affected by the bed forms, but in the rivers it was of little difference between the gravel-bed and sand-bed.

• Journal of Korea Water Resources Association
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• v.55 no.10
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• pp.801-810
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• 2022

This study investigates the evolution processes of alternate bars in the channel with bank stability by vegetation by laboratory experiment. Laboratory experiments are conducted to elucidate the behavior of alternate bars by the influence of riparian vegetation on the rivers with erodible banks. To control bank stability of the channel, the actual vegetation, alfalfa, is grown by adjusting the density of alfalfa on the flood plain. As the vegetation density increases in the flood plain, the bank erosion rates and the channel widening rates decrease and the bank stability increases. The alternate bars migrate slow downstream over time. Moreover, the bars in a channel with strong banks migrate rapidly, which is related with the aspect ratio, that is, width to depth ratio. The bar wavelength decrease with vegetation density. Our laboratory experiments show that the behavior of bars differ according to bank strength.

• Geomechanics and Engineering
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• v.28 no.6
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• pp.613-624
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• 2022

A study of the evolution of overburden fractures under the solid-fluid coupling state was conducted based on the geological and mining characteristics of the coal seam depth, weak strata cementation, and high-intensity mining in the mining areas of West China. These mining characteristics are key to achieving water conservation during mining or establishing groundwater reservoirs in coal mines. Based on the engineering background of the Daliuta Coal Mine, a non-hydrophilic simulation material suitable for simulating the weakly cemented rock masses in this area was developed, and a physical simulation test was carried out using a water-sand gushing test system. The study explored the spatial distribution and dynamic evolution of the fractured zone in the mining overburden under the coupling of stress and seepage. The experimental results show that the mining overburden can be vertically divided into the overall migration zone, the fracture extension zone and the collapse zone; additionally, in the horizontal direction, the mining overburden can be divided into the primary fracture zone, periodic fracture zone, and stop-fracture zone. The scope of groundwater flow in the overburden gradually expands with the mining of coal seams. When a stable water inrush channel is formed, other areas no longer generate new channels, and the unstable water inrush channels gradually close. Finally, the primary fracture area becomes the main water inrush channel for coal mines. The numerical simulation results indicate that the overlying rock breaking above the middle of the mined-out area allows the formation of the water-conducting channel. The water body will flow into the fracture extension zone with the shortest path, resulting in the occurrence of water bursting accidents in the mining face. The experimental research results provide a theoretical basis for the implementation of water conservation mining or the establishment of groundwater reservoirs in western mining areas, and this theoretical basis has considerable application and promotion value.

• Geophysics and Geophysical Exploration
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• v.14 no.4
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• pp.289-297
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• 2011

Chirp sub-bottom profilers (SBP) data are comparatively higher-resolution data than other seismic data and it's raw signal can be used as a final section after conducting basic filtering. However, Chirp SBP signal has possibility to include various noise in high-frequency band and to provide the distorted image for the complex geological structure in time domain. This study aims at the goal to establish the workflow of Chirp SBP data processing for enhanced image and to analyze the proper parameters for the domestic continental shelf. After pre-processing, we include the dynamic S/N filtering to eliminate the high-frequency component noise, the dip scan stack to enhance the continuity of reflection events and finally the post-stack depth migration to correct the distorted structure on the time domain sections. We demonstrated our workflow on the data acquired by domestically widely used equipments and then we could obtain the improved seismic sections of depth domain. This workflow seems to provide the proper seismic section to interpretation when applied to data processing of Chirp SBP that are largely used for domestic acquisition.

• Journal of Periodontal and Implant Science
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• v.23 no.3
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• pp.359-373
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• 1993

The ultimate objective of periodontal therapy is not only stopping the progression of periodontal disease, but also promoting the regeneration of lost periodontal tissue. Guided Tissue Regeneration, which is based on the principle that the goal of periodontal regeneration can be achieved by preventing apical migration of gingival epithelium and blocking cells originating from connective tissue, has been developed and used as a clinical procedure, and although it has shown excellent results in connective tissue healing, there have not been many studies showing its effect on the regeneration of alveolar bone loss due to periodontal disease. The objectives of this study are to investigate the result of 12 months-long treatment following guided tissue regeneration using expanded polytetrafluoroehylene membrane, and to observe the presence of regenerated alveolar bone. Forty-one teeth from 28 patients with clinical diagnosis of periodontitis has been selected. In fifteen of those interproximal intrabony defects, only flap operation had been carried out, and designated as the control group. Twenty-six intrabony defects received e-PTFE membrane following flap operation, and designated as the experimental group. Eleven teeth whose membrane had been exposed were excluded from the experiment. Various measurements including probing depth, loss of attachment, probing bone level and gingival recession have been recorded at 6th month and 12th month, and the significance of the changes has been analyzed. The results are as follows: 1. Probing depth at 6th and 12th month has shown a significant decrease in both groups (p<0.01), but significantly higher decrease was found in the experimental group compared to the control at the month(p<0.05). 2. Loss of attachment at 6th and 12th month has shown a significant decrease in both groups, but significantly higher decrease was found in the experimental group compared to the control (p<0.05). 3. Probing bone level at 6th and 12th month has shown a insignificant decrease in the control group and significant decrease in the experimental group (p<0.01). Significantly higher decrease in probing bone level was found in the experimental group (p<0.05). 4. Gingival recession at 6th and 12th month has shown a statistically significant increase (p<0.05), and the control group showed higher increase compared to the experimental group although no statistical significance was found. As these results have shown, the use of e-PTFE membrane in intrabony pockets results in marked decrease in the loss of attachment and probing bone level. This seems to indicate that e-PTFE membrane may play a role in alveolar bone regeneration in intrabony defects.