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Epidemiological Characteristic and Risk Factor of COVID-19 Cluster Related to Educational Facilities in Gangwon-do, Korea (December 10, 2020-September 23, 2021) (강원도내 교육시설관련 코로나바이러스감염증19 집단발생의 역학적특성과 위험요인 (2020.12.10-2021.9.23))

  • Hyosug Choi;Mi Young Kim;Shinyoung Lee;Eunmi Kim;Yeo Jin Kim
    • Pediatric Infection and Vaccine
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    • v.31 no.1
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    • pp.102-112
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    • 2024
  • Purpose: To identify the epidemiological characteristics and risk factors of coronavirus disease 19 (COVID-19) outbreaks depending on the type of educational facility by analyzing the COVID-19 cluster associated with educational facilities. Methods: This study is based on epidemiological investigation of COVID-19 cluster in Gangwon-do, Korea from December 10, 2020 to September 23, 2021 reported to the Korea Disease Control and Prevention Agency's Integrated Disease and Health Management System. Four hundred seven patients in 19 facilities, classified as cluster related to educational facilities, were the study population. The result of preliminary epidemiology survey report, in-depth epidemiological survey by phone and the result of risk assessment derived from the field epidemiology investigation were retrospectively analyzed to evaluate infectivity and the characteristics of the risk factors. Results: There were total of 407 confirmed patients related to 19 educational facilities, with 204 students under the age of 19 (50.1%). One hundred fifty-five preceding spreaders were from families (38.1%) and 125 were the teachers (30.7%). The place exposed to confirmed patients was the highest with 139 people (34.2%) at home. Conclusions: It was confirmed that the cause of the occurrence of clusters related to educational facilities was higher due to family transmission than the risk of facilities in schools. Nevertheless, continuous efforts should be made to control infection in educational facilities, and that teachers' implementation of principles for prevention of COVID-19 personal hygiene in their daily lives should be strengthened.

Characteristics of Element Geochemistry in Ulleung Basin Sediments During the Late Quaternary (제4기 후기 동안 동해 울릉분지 퇴적물내 원소 함량 특성과 기원지 연구)

  • Um, In-Kwon;Choi, Man-Sik;Shin, Hyung-Sun
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.14 no.2
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    • pp.69-79
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    • 2009
  • Major and trace elements were analyzed in three core sediments to investigate geochemical characteristics of East Sea sediments and provenance changes during late Quaternary in Ulleung Basin. Comparing with Yellow and South Sea sediments, contents of major elements were generally similar while contents of trace elements were significantly different. Furthermore, within this basin, there were some variabilities in trace element compositions. In the western slope sediments (WS), Mo was enriched over 6 times as much as other sites. On the other hand, Zr, Nb, Hf and Ta were enriched in basin sediments (Basin), and Ca and Cs were enriched in southern slope sediments (SS). After excluding elements derived from biogenic, authigenic and diagenetic origins, the lithogenic elements (K, Ti, Cs, Zr, Nb, Hf and Ta) could be classified into three groups from the comparison of element/Al ratios among cores. The first group consisted of elements (K and Ti) that showed the nearly similar element/Al ratios among three cores. The second group contained Cs which showed significant difference between two slope sediments. The third group elements (Zr, Nb, Hf and Ta) showed highly enriched in basin relative to both slope areas. The depth profiles of metal/Al ratios in basin sediments provided the following interpretation for the compositions of sediment and their variation. From 10,000 yr B.P. to 7,000 yr B.P. two lithogenic components (volcanic ashes and western slope sediments) were mixed and deposited in the basin. After 7,000 yr B.P., however, southern slope sediments were mixed with volcanic ashes and deposited in basin area. This event of source change is nearly close to inflow period of the Tsushima Warm Current to Ulleung Basin. Thus, it might be suggested that element geochemistry in Ulleung basin sediment indicate the change of current system in the study area.

Macrobenthic Community Structure Along the Environmental Gradients of Ulsan Bay, Korea (울산만의 저서환경 구배에 따른 저서동물군집 구조)

  • Yoon, Sang-Pil;Jung, Rae-Hong;Kim, Youn-Jung;Kim, Seong-Gil;Choi, Min-Kyu;Lee, Won-Chan;Oh, Hyun-Taik;Hong, Sok-Jin
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.14 no.2
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    • pp.102-117
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    • 2009
  • This study was carried out to investigate the extent to which benthic environment of Ulsan Bay was disturbed by organic materials and trace metals from the megacity and industrial complex. Field survey for benthic environment and macroinvertebrate community was seasonally conducted from February to November 2006 at nine stations covering the inside and outside of the bay. TOC was on average 1.7% while four (As, Cu, Pb, Zn) out of seven trace metals measured exceeded the Effects Range Low (ERL) in most of the stations. Total number of species sampled was 199 and mean density was 4,578 ind./$m^2$, both of which were greatly dominated by the polychaetes. Dominant species were Aphelochaeta monilaris (22.6%), Ruditapes philippinarum (17.1%), Magelona japonica (12.2%), Lumbrineris longifolia (9.9%) and their distribution was ruled by the difference in the benthic environmental condition of each station. From the multivariate analyses, four stational groups were identified: northern part of the bay, middle and lower part of the bay, the intersection of Taewha River and Gosa stream and outside of the bay. As a result, the community heterogeneity of inner bay was much more greater than that of outer bay. SIMPER analysis showed that four groups were represented by R. philippinarum-Capitella capitata, A. monilaris-Balanoglossus carnosus, Sinocorophium sinensis-Cyathura higoensis and M. japonica-Ampharete arctica, respectively. Spatio-temporal changes of macroinvertebrate communities in Ulsan Bay were closely related to those of depth, mean grain size and organic content, and Zn was also a meaningful factor in that context.

Seasonal Variations of Particle Fluxes in the Northeastern Pacific (북동태평양 심해에서 관측된 퇴적물 입자 플럭스의 계절적 변동)

  • Kim, Hyung-Jeek;Kim, Dong-Seon;Hyeong, Ki-Seong;Kim, Kyeong-Hong;Son, Ju-Won;Hwang, Sang-Chu;Chi, Sang-Bum;Kim, Ki-Hyun;Khim, Boo-Keun
    • The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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    • v.13 no.3
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    • pp.200-209
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    • 2008
  • Particle fluxes were measured with a time-series sediment trap from July 2003 to June 2005 at the St. KOMO(KOMO; Korea Deep-Sea Environmental Study Long-Term Monitoring Station, $10^{\circ}30'N,\;131^{\circ}20'W$) in the northeastern Pacific. Total mass fluxes at a depth of 4,960 m showed distinct seasonal variations with high values in the winter(December-February) and spring(March-May) and low values in the summer(June-August) and fall(September-November). Biogenic origin fluxes also displayed distinct seasonal variations similar to total mass fluxes. Particularly, calcium carbonate fluxes in winter and spring were more than two times greater than those in summer and fall. The prominent seasonal variations of total mass and biogenic fluxes were closely related with the seasonal changes of primary production in the surface waters; in winter and spring, primary production increased due to the enhanced supply of nutrients below the surface mixed layer by strong wind and less stratification, whereas it decreased as a result of the less supply of nutrient by reduced wind speed and strong stratification in summer and fall. The seasonal variations of total mass and biogenic fluxes in this study were higher than the differences of total mass and biogenic fluxes caused by the environmental changes such as El $Ni\tilde{n}o$ and La $Ni\tilde{n}a$ events in the previous studies. In order to understand the effects of El $Ni\tilde{n}o$ and La $Ni\tilde{n}a$ on the particle flux, therefore, the seasonal variation of particle flux in the northeastern equatorial Pacific needs to be well defined.

A Study on the Discourse Regarding the Lineage Transmission to Haewol in the Eastern Learning: Focused on Document Verification (해월의 동학 도통전수 담론 연구 - 문헌 고증을 중심으로 -)

  • Park Sang-kyu
    • Journal of the Daesoon Academy of Sciences
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    • v.48
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    • pp.41-155
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    • 2024
  • Among the records that attest to the period from July to August of 1863, when Suwun was believed to have transmitted the orthodox lineage to Haewol, the oldest documents are The Collection of Suwun's Literary Works (水雲文集), The Collection of Great Master Lord's Literary Works (大先生主文集), and The Records of Dao Origin of Master Choe's Literary Collection (崔先生文集道源記書, hereafter referred to as The Records of Dao Origin). The records regarding Suwun in these three documents are considered to have originated from the same context. The variances embedded in the three documents have led to arguments about which documents accurately reflect the fact of orthodox lineage transmission. Additionally, these variances highlight the necessity of a review regarding the characteristics of early Eastern Learning, such as its faith and organizational systems. Accordingly, by thoroughly examining these three documents, it is possible to elucidate the chronological order, establishment-date, accuracy, descriptive direction, and characteristics of the faith system of early Eastern Learning as these are reflected in each document. If successful, this examination would provide a clearer description of the developmental process of Eastern Learning from 1860 to 1880, facilitating a more in-depth analysis of the significance embedded in various forms of discourse on the movement's orthodox lineage transmission. In comparing the three documents and contrasting them with related sources, the results of the textual examination assert that the documents within the lineage of The Collection of Suwun's Literary Works, given they lack a clear record of the event regarding Haewol's orthodox lineage succession, may be the first draft of The Collection of Great Master Lord's Literary Works and The Records of Dao Origin, as these texts distinctly include that record. This reflects that Haewol's succession was not precisely recognized within and outside of the Eastern Learning order until the time when The Collection of Great Master Lord's Literary Works and The Records of Dao Origin were published. This is further attested to by the fact that during the late 1870s, when various Yeonwon (fountainhead) factions of Eastern Learning began to converge around Haewol, and his Yeonwon became the largest organization within Eastern Learning. At that point, the order's doctrine was reinterpreted, and its organization was reestablished. In this regard, it is necessary to view Eastern Learning after Suwun-especially the orthodox lineage transmission to Haewol-from a perspective that considers it more as competing forms of discourse than as a historical fact. This view enables a new perspective on Haewol's Eastern Learning, which forms a distinct layer from Suwun's, shedding light on the relationship between Haewol and the new religious movements in modern-day Korea.

A Study on Space Creation and Management Plan according to Characteristics by Type in Each Small-Scale Biotope in Seoul - Base on the Amphibian Habitats - (서울시 소규모 생물서식공간 유형별 특성에 따른 조성 및 관리방안 연구 - 양서류 서식지를 중심으로 -)

  • Park, Ha-Ju;Han, Bong-Ho;Kim, Jong-Yup
    • Journal of the Korean Institute of Landscape Architecture
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    • v.52 no.2
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    • pp.110-126
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    • 2024
  • This study conducted a classification of small-scale biological habitats created in Seoul to analyze and synthesize location characteristics, habitat structure, biological habitat functions, and threat factors of representative sites, as well as derive creation and management problems according to the ecological characteristics. The aim was to suggest improvement measures and management items. Data collected through a field survey was used to categorize 39 locations, and 8 representative sites were selected by dividing them into location, water system, and size as classification criteria for typification. Due to the characteristics of each type, the site was created in an area where amphibian movement was disadvantageous due to low or disconnected connectivity with the hinterland forest, and the water supply was unstable in securing a constant flow and maintaining a constant water depth. The habitat structure has a small area, an artificial habitat structure that is unfavorable for amphibians, having the possibility of sediment inflow, and damage to the revetment area. The biological habitat function is a lack of wetland plants and the distribution of naturalized grasses, and threats include the establishment of hiking trails and decks in the surrounding area. Artificial disturbances occur adjacent to facilities. When creating habitats according to the characteristics of each type, it was necessary to review the possibility of an artificial water supply and introduce a water system with a continuous flow in order to connect the hinterland forest for amphibian movement and locate it in a place where water supply is possible. The habitat structure should be as large as possible, or several small-scale habitats should be connected to create a natural waterfront structure. In addition, additional wetland plants should be introduced to provide shelter for amphibians, and facilities such as walking paths should be installed in areas other than migration routes to prevent artificial disturbances. After construction, the management plan is to maintain various water depths for amphibians to inhabit and spawn, stabilize slopes due to sediment inflow, repair damage to revetments, and remove organic matter deposits to secure natural grasses and open water. Artificial management should be minimized. This study proposed improvement measures to improve the function of biological habitats through the analysis of problems with previously applied techniques, and based on this, in the future, small-scale biological habitat spaces suitable for the urban environment can be created for local governments that want to create small-scale biological habitat spaces, including Seoul City. It is significant in that it can provide management plans.

Distribution, Preservation Characteristics of Land and River Natural Aggregates in Nonsan City, Korea (논산시 하천 및 육상 골재 자원의 부존 현황과 특성)

  • Hyun Ho Yoon;Sei Sun Hong;Min Han;Jin-Young Lee
    • Economic and Environmental Geology
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    • v.57 no.2
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    • pp.143-159
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    • 2024
  • Natural aggregate is an essential resource for human activities, closely related to construction. The aggregate demand has been increasing annually, and due to the nature of the resource, it is difficult to procure from distant locations. This study identifies the distribution and characteristics of aggregate-bearing areas as part of a municipal-level aggregate resource survey conducted in Nonsan City, Korea, in 2023. Nonsan City is located approximately 35 km straight distance from the Geum River estuary and lies at the passageway of the main stream of the Geum River. The topography of Nonsan City features eastern mountainous areas and western plains, creating an east-high-west-low geomorphic setting, with 33 streams distributed across the city, including tributaries of the Geum River like Nonsan Stream, Noseong Stream, and Ganggyeong Stream. All streams originate from the highlands in the north and east, converge with Nonsan Stream, and then join the west bank of the main stream of the Geum River at the western boundary of Nonsan City. Drilling core results show shallow depths in the highlands to the north and east, deepening towards the west, reaching a maximum depth of 25 m near the main stream of the Geum River. The total reserve of land aggregates is calculated to be 246,789,000 m3, with a developable amount of 172,750,000 m3. The total reserve of river aggregates is 5,236,000 m3, with a developable amount of 3,765,000 m3. The distribution of aggregates varies according to the geomorphic, geologic, and development pattern of the river system. Reserves are scarce in mountainous areas but are abundant in regions with rivers and wide alluvial plains, although reserves appear at depths greater than 4m. The distribution of aggregate resources in Nonsan City is influenced by stream activities and sea level changes, with the tidal range of the Yellow Sea acting as an unfavorable condition for the preservation of aggregate resources.

Distribution Characteristics of Land and River Aggregate Resources in Yeongam Area by Deposition Period (영암지역 육상 및 하천 골재의 퇴적 시기별 분포 특성)

  • Jin Cheul Kim;Sei Sun Hong;Jin-Young Lee;Ju Yong Kim
    • Economic and Environmental Geology
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    • v.57 no.2
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    • pp.243-251
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    • 2024
  • In this study, a surface geological survey was first conducted to investigate aggregate resources in the Yeongam area of Jeollanam-do, and a drilling survey was conducted in the lower part of the surface, which was difficult to identify through a surface geological survey, to determine the spatial distribution of aggregates. Drilling sites were selected considering the topographical development and Quaternary alluvium characteristics of the study area, and river aggregate drilling surveys were conducted at a total of 5 points and land aggregate drilling surveys were conducted at a total of 28 points. Borehole core sediments were classified into seven sedimentary units to determine whether they could be used as aggregates, and optically stimulated luminescence dating was performed on representative boreholes to measure the depositional period for each sedimentary unit. As a result of the study, most of the Yeongam area had a very wide river basin, so it was estimated that there would be a large amount of aggregate, but the amount of aggregate was evaluated to be very small compared to other cities and counties. Most of the unconsolidated sedimentary layers in the Yeongam area are composed of blue-grey marine clay with a vertical thickness of more than 10 m. The sand-gravel layer corresponding to the aggregate section is distributed in the lower part of the marine clay, thinly covering the bedrock weathering zone. This is because the amount of aggregates themselves is small and most of the aggregates are distributed at a depth of 10 m below the surface, which is currently difficult to develop, so the possibility of developing aggregates is evaluated to be very low. As a result of dating, it can be seen that the blue-grey marine clay layer is an intertidal sedimentary layer formed as the sea level rose rapidly about 10,000 years ago. The deposition process continued from 10,000 years ago to the present, and as a result, a very thick clay layer was deposited. This clay layer was formed very dominantly for about 6,000 to 8,000 years, and the sand-gravel layer in the section where aggregates deposited in the Pleistocene period can exist was measured to have been deposited at about 13.0 to 19.0 ka, and about 50 ka, showing that it was deposited as paleo-fluvial deposits before the marine transgression process.

Comprehensive profiling of DNA methylation in Korean patients with colorectal cancer

  • Hyeran Shim;Kiwon Jang;Yeong Hak Bang;Hoang Bao Khanh Chu;Jisun Kang;Jin-Young Lee;Sheehyun Cho;Hong Seok Lee;Jongbum Jeon;Taeyeon Hwang;Soobok Joe;Jinyeong Lim;Ji-Hye Choi;Eun Hye Joo;Kyunghee Park;Ji Hwan Moon;Kyung Yeon Han;Yourae Hong;Woo Yong Lee;Hee Cheol Kim;Seong Hyeon Yun;Yong Beom Cho;Yoon Ah Park;Jung Wook Huh;Jung Kyong Shin;Dae Hee Pyo;Hyekyung Hong;Hae-Ock Lee;Woong-Yang Park;Jin Ok Yang;Young-Joon Kim
    • BMB Reports
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    • v.57 no.2
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    • pp.110-115
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    • 2024
  • Alterations in DNA methylation play an important pathophysiological role in the development and progression of colorectal cancer. We comprehensively profiled DNA methylation alterations in 165 Korean patients with colorectal cancer (CRC), and conducted an in-depth investigation of cancer-specific methylation patterns. Our analysis of the tumor samples revealed a significant presence of hypomethylated probes, primarily within the gene body regions; few hypermethylated sites were observed, which were mostly enriched in promoter-like and CpG island regions. The CpG Island Methylator Phenotype-High (CIMP-H) exhibited notable enrichment of microsatellite instability-high (MSI-H). Additionally, our findings indicated a significant correlation between methylation of the MLH1 gene and MSI-H status. Furthermore, we found that the CIMP-H had a higher tendency to affect the right-side of the colon tissues and was slightly more prevalent among older patients. Through our methylome profile analysis, we successfully verified the methylation patterns and clinical characteristics of Korean patients with CRC. This valuable dataset lays a strong foundation for exploring novel molecular insights and potential therapeutic targets for the treatment of CRC.

Periodontal status of end-stage renal disease patients undergoing dialysis and referred for intraoral evaluation prior to kidney transplant surgery (투석을 받고 있으며 신장 이식 수술 전 구강내 평가를 위해 의뢰된 말기 신장 질환 자의 치주 상태)

  • Youn-Kyung Choi;Hye-Mi Jeon;Ji-Young Joo;Hyun-Joo Kim;Eun-Young Kwon
    • Journal of Dental Rehabilitation and Applied Science
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    • v.40 no.2
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    • pp.46-54
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    • 2024
  • Purpose: The purpose of this study was to compare the periodontal status of end-stage renal disease patients undergoing dialysis and referred for intraoral evaluation prior to renal transplantation surgery with those having normal kidney function. Materials and Methods: Patients who had been undergoing dialysis for end-stage renal disease and been referred to the Dental Clinic Center by the Department of Nephrology at University Hospital for intraoral evaluation prior to kidney transplantation surgery. For comparison of periodontal status, subjects without abnormalities in kidney function were matched with the patients by age and gender and selected as healthy controls. The patients' age, gender, comorbidities, type of dialysis received, and duration of dialysis were investigated by reference to their medical records, and data on their periodontal status were analyzed via the relevant periodontal records. Results: A total of 102 patients, including 51 dialyzed patients and 51 healthy control group subjects, participated in this study. In the patients with end-stage renal disease undergoing dialysis with periodontal probing depth of 5 mm or more, percentage of sites with clinical attachment level of 4 mm or more, percentage of teeth with bleeding on probing, number of missing teeth, and ratio of moderate to severe periodontitis were all significantly greater than in the healthy controls. Conclusion: The periodontal status of end-stage renal disease patients undergoing dialysis and referred for intraoral evaluation prior to kidney transplantation was worse than that of healthy controls.