• 한국응용과학기술학회지
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• 제35권2호
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• pp.532-539
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• 2018

본 연구는 건강신념모형을 적용하여 임상에서 근무하는 간호사의 손씻기 수행도를 분석하기 위한 서술적 조사연구이다. 본 연구의 대상은 G 광역시에 위치한 일개 병원에 근무하는 임상 간호사 162명이다. 자료수집은 2017년 9월 1일부터 2017년 10월 31일까지였다. 수집된 자료는 SPSS (SPSS Version 20.0, IBM, US)를 이용하여 빈도분석, 백분율, 일원분산분석, t-검정, pearson 상관계수분석 및 다중회귀분석으로 통계처리 하였다. 일반적 특성에 따른 손씻기에 대한 수행도는 모든 영역에서 평균은 3.1점으로 높았으나 통계적으로 유의한 차이는 보이지 않았다. 일반적 특성에 따른 손씻기에 대한 건강신념은 연령에서는 지각된 유익성 영역에서 유의한 차이를 보였으며(p<0.05), 근무연수에서는 지각된 유익성, 지각된 장애성 영역에서 유의한 차이를 보였다(p<0.05). 다섯 개의 하위영역간의 상관관계를 분석한 결과는 지각된 유익성과 지각된 장애성은 부의 상관관계를 나타냈으며, 수행을 위한 동기는 정의 상관관계를 보였다. 본 연구의 결과를 통해 손씻기에 대한 건강신념을 고려한 지속적인 병원에서의 감염관리교육과 올바른 손씻기 교육을 진행한다면 손씻기 수행도가 높아질 것으로 판단된다.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제32권6호
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• pp.566-574
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• 2006

Purpose : This study was performed to provide an anatomical information of the mandibular ramus for the successful inferior alveolar nerve block. Three dimensional images were reconstructed from the computerized tomography (CT) and the anatomical evaluation of the mandibular ramus was done. Materials and methods : Sixty-four patients who had been taken the facial CT scans from 2000, Jan to 2003, June was selected. The patients who had the anterior or posterior teeth misssing, edentulous ridge, and jaw fracture were excepted. In the occulusal plane, the lingual surface angle (LSA) between the mid-sagittal plane and the mandibular molar lingual surface from the 2nd premolar to the 2nd molar, the inner ramal surface angle (IRSA), the maximum inner ramal surface angle (MxIRSA), and the outer ramal surface angle (ORSA) to the-mid sagittal plane were measured. The inner ramal surface angle in the ligular tip level (IRSA-L) and the outer ramal surface angle in the ligular tip level (ORSA-L), the ramal length (RL), and the anterior ramal length (ARL) were also measured in the lingular tip level. Results : In the lingular tip level, the mean IRSA-L and ORSA-L were $28.6{\pm}6.3^{\circ}$ and $17.9{\pm}4.9^{\circ}$ respectively. The larger was the IRSA, the larger was the ORSA. In the lingular tip level, the mean ramal length was 35.8${\pm}$3.4 mm. The larger was the IRSA-L, the shorter was the ramal length. On the lingular tip level, the mean anterior ramal length from anterior ramus to lingular tip was 19.6${\pm}$3.3 mm. when the ramal length was longer, the anterior ramal length was also longer. On the lingular tip level, there was positive correlation vetween the IRSA and the ORSA, negative correlation between the IRSA and the ramal length, and positive correlation between the ramal length and the lingular tip level to the anterior ramus. There was no statistical meaning of data between sex and age. Conclusion : In the clinical view of the results so far achieved, if the direction of needle is closer to posterior it is able to contact bone on lingular tip when the internal surface of ramus is wided outer.

• Journal of Biosystems Engineering
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• 제39권2호
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• pp.122-133
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• 2014

Purpose: This study was to develop an effective process for fabricating biocompatible calcium phosphate powders (CPPs) using horse bones, and to investigate the characteristics of them. Methods: The characteristics of horse bone powders (HBPs) were investigated according to the different osseous tissue types (compact bone and cancellous bone), bone types (spine and tibia), pretreatment methods (cold water, $H_2O_2$, and hot water), sintering time (4, 8 and 12h), and sintering temperature (600, 900, 1100 and $1300^{\circ}C$). In addition, the grinding methods were compared based on the wet grinding (ball mill) and dry grinding (blade grinder) method to make it as powders. Finally, their cytotoxicity and cell viability were checked. Results: Regardless of the types of osseous tissues and bones, HBPs were well fabricated as biocompatible CPPs. It was also found that the pretreatment methods did not influence on the resultants, showing well-fabricated HBPs. Considering the processing time, the hot water method was the most suitable compared to other pretreatment methods. Further, 12h-sintering time was sufficient to remove residual organic compounds. The sintering temperatures greatly affected the properties of bone powders fabricated. The x-ray diffraction (XRD) peak of horse bone sintered at $600^{\circ}C$ was most closed to that of hydroxyapatite (HA). Our bioactivity study demonstrated that the HBPs fabricated by sintering horse bones at $1300^{\circ}C$ showed the best performance in terms of cell viability whereas the HBPs $1100^{\circ}C$ showed the cytotoxicity. Conclusions: Using various types of horse bone tissues, biocompatible CPPs were successfully developed. We conclude that the HBPs may have a great potential as biomaterials for various biological applications including bone tissue engineering.

• 한국초지조사료학회지
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• 제32권2호
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• pp.165-174
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• 2012

본 연구는 반추동물의 조사료 자원으로서 거대억새를 개발하기 위한 목적으로 수행되었다. 우리나라에서 새롭게 개발된 품종인 거대억새 1호를 완숙기 이후에 채취하여 in vitro 반추위 발효를 이용해 반추위내 pH, 암모니아태 질소, 가스발생량, 휘발성 지방산 생성량 및 건물소화율을 조사하였으며, 볏짚과 비교하여 평가하였다. 거대억새는 볏짚에 비하여 유의적으로 높은 반추위내 pH를 나타내었다(p<0.01). 암모니아태 질소의 경우 배양 12시간 이후에는 두 처리구간의 유의적인 차이를 나타내지 않았다 (p>0.05). 배양 6시간 이후 부터는 거대억새의 가스발생량이 볏짚에 비하여 유의적으로 낮게 나타났다 (p<0.05). 휘발성 지방산 생성량에 있어 acetate, propionate, butyrate, valerate 및 총생상량에서 볏짚이 거대억새보다 높게 나타났다. 그러나 iso-butyrate와 iso-valerate에서는 두 조사료원별 차이는 발견되지 않았다. 건물소화율에 있어 배양 12~24시간 사이의 거대억새 소화율이 볏짚에 비하여 유의적으로 나타났다. 결론적으로 거대억새의 이용성은 볏짚의 약 80% 수준인 것으로 나타났다.

• 대한수의학회지
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• 제24권2호
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• pp.183-193
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• 1984

In this study lactating female rabbits and strains of coliforms previously isolated from the cases of acute and chronic mastitis in dairy cattle were employed. The pathological changes were observed on the mastitis experimentally induced with the coliform strains and the mamary glands after infusions of E. coli suspension together with dexamethasone, dextran iron or transferrin were grossly and microscopically observed. From the results reported, the following points are concluded. In the bacterial suspension-infused groups by E. coli, K. pneumoniae and Ent. aerogenes, respectively, the affected quarters of udder showed grossly swelling, hyperemia, hemorrhage, focal necrosis and firmness. The microscopic findings of early stage of the mastitis were appearance of large numbers of heterophils in the glandular lumina and ducts accompanied by degeneration, necrosis and desquamation of epithelial cells and also infiltration of heterophils, hemorrhage and edema in the interstitial tissue and destruction of alveoli. Later, proliferation of fibroblasts, plasma cells, lymphocytes, eosinophils and macrophages appeared in the glandular tissue and with these cells necrotic foci of glandular tissue were surrounded by highly proliferated connective tissue. In addition, granulomatous inflammatory changes could be observed in the glandular tissue from the 7th day after infusion. The difference of the inflammatory response among the groups did not recognized. In the groups infused with dexamethasone and E. coli suspension the inflammatory response was slighter at the inflammatory change with alveolar destruction and hemorrhage was more rapid and severer than E. coli alone. Also in the groups infused with dextran iron and E. coli suspension the inflammatory change was more rapid and severer than E. coli alone and the histological changes were not recognized in the groups infused with dextran iron alone. Reaction of the iron staining was diffusely strong positive within the glandular alveolar lumina in the groups of dextran iron alone, hut was slightly positive toward epithelial cells in the groups of dextran iron and E. coli infusion. In the group infused with transferrin and E. coli suspension, the inflammatory response was tighter, but the peroxidase activity of the heterophils in the glandular lumina was more or less stronger than E. coli alone.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제30권3호
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• pp.193-202
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• 2004

Distraction osteogenesis(DO) is defined as a gradual mechanical process of mechanical stretching two vascularized bone surface apart with a critical rate and rhythm such that new bone forms within the expanding gap, reliably bridges the gap, and ultimately remodels to normal structure. DO has become a mainstay in bone tissue engineering and has significantly improved our armamentarium for reconstructive craniomaxillofacial procedures. But the molecular and biological mechanisms that regulate the formation of new bone during distraction osteogenesis are not completely understood. BMPs are potent osteoinductive agents. Our hypothesis was that BMPs, especially BMP-2 and BMP-4, might play an importent role in the signaling pathways that link the mechanical forces created by distraction to biological responses and in promting new bone formation. Using a rabbit's mandible, we investigated the expression of BMP-2, -4 at different time points during distraction osteogenesis. The purpose of this study is to research the pattern of expression of BMP-2, -4 in new bone formation during distraction osteogenesis of the rabbit mandible. The experimental group was applied gradual distraction (0.7mm a day by twice a day, 4.9mm in total, for 7 days) and the control group was carried out osteotomy alone. They were examined clinically, histologically, and by RT-PCR analysis. On 3 days after osteotomy, the high level of expression of BMP-2, -4 was detected. But, the expression of BMP-4 was decreased during latency period. As distraction was started, its expression was increased and maintained till postoperative 28days. In control group, the expression of BMP-4was remarkably decreased till postoperative 14 days. On the other hand, the expression of BMP-2 was no difference between experimental group and control group. The expression of BMP-4 was maintanined at high level during the entire experimental period in both group. These findings suggested that excellent bone formation during distraction osteogenesis is associated with enhanced expression of BMP-4 genes by mechanical tension stress.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제34권1호
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• pp.99-107
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• 2008

Objective : The objective of this review was to provide reliable comparative results regarding the effectiveness of any interventions either open or closed that can be used in the management of fractured mandibular condyle Patients and Methods : Research of studies from MEDLINE and Cochrane since 1990 was done. Controlled vocabulary terms were used. MeSH Terms were "Mandibular condyle" AND "Fractures, bone". Only comparative study were considered in this review using the "limit" function. According to the criteria, two review authors independently assessed the abstracts of studies resulting from the searches. The studies were divided according to some criteria, and following were measured: Ramus height, condyle sagittal displacement, condyle Towns's image displacement, Maximum open length, Protrusion & Lateral excursion, TMJ pain, Malocclusion, and TMJ disorder. Results : Many studies were analyzed to review the post-operative result of the two methods of treatment. Ramus height decreased more in when treated by closed reduction as opposed to open reduction. Sagittal condyle displacement was shown to be greater in closed reduction. Condyle Town's image condyle displacement had greater values in closed reduction. Maximum open length showed lower values in closed reduction. In protrusive and lateral movement, closed reduction was less than ORIF. Closed reduction showed greater occurrence of malocclusion than ORIF. However, post-operative pain and discomfort was greater in ORIF. Conclusion : In almost all categories, ORIF showed better results than CRIF. However, the use of the open reduction method should be considered due to the potential surgical morbidity and increased hospitalization time and cost. To these days, Endoscopic surgical techniques for ORIF (EORIF) are now in their infancy with the specific aims of eliminating concern for damage to the facial nerve and of reducing or eliminating facial scars. Before performing any types of treatment, patients must be understood of both of the treatment methods, and the best treatment method should be taken on permission.

• 대한치과보철학회지
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• 제50권2호
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• pp.99-105
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• 2012

연구 목적: 지금까지 성공적인 임플란트 치료를 위해 많은 연구가 진행되어 왔으며, 임플란트 주변 골 흡수 현상에 대한 연구는 매우 관심이 높은 분야 중 하나이다. 이에 본 연구에서는 삼차원 유한요소응력분석을 이용하여 변연골 흡수가 내측연결 임플란트 매식체의 기계적 안정성에 미치는 영향을 간접적으로 확인하고자 하였다. 연구 재료 및 방법: 악골에 식립된 내측연결 형태의 임플란트 매식체에 티타늄 소재의 임플란트 지대주를 지대주 나사로 연결하고 상부에 금합금관을 장착하는 삼차원 유한요소모형을 설계하였다. 0, 1, 2, 3 mm의 변연골 흡수 상태를 적용하고, 교합면 중심에서부터 3 mm 편측에 300 N의 수직 하중을 가하여 임플란트 매식체에 발생하는 최대 주 응력을 계산하였다. 결과: 유한요소분석결과 변연골 흡수에 따른 임플란트 매식체의 최대 주응력 분포는 유사한 양상을 보였으며, 임플란트 매식체 상단에서 가장 높은 응력 집중이 나타났다. 최대 주응력은 처음 1 mm 변연골 흡수를 가정하였을 때 가장 크게 증가하였고, 이후 변연골 흡수가 증가할수록 응력은 증가하였지만 응력 증가의 폭은 감소하는 경향을 보였다. 결론: 이러한 결과로부터 내측연결 임플란트에서 매식체 두께가 얇은 경부의 노출은 변연골 흡수로 인한 응력 증가에 가장 큰 원인임을 알 수 있었으며, 매식체의 변형, 균열 및 파절 등의 기계적 실패를 감소시키기 위해서는 이에 대한 외과적, 보철적 고려가 필요할 것으로 생각된다.

• 구강회복응용과학지
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• 제28권1호
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• pp.87-101
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• 2012

이갈이는 이를 갈거나 악무는 것을 포함하는 부기능적인 행위를 말하며 광범위하게는 주간 및 야간에 나타나는 것을 모두 포함한다. 이갈이의 원인으로는 기본적으로 말초성 요인과 중추성 요인으로 나누어 살펴볼 수 있는데 현재까지의 연구 결과를 종합하여 볼 때 중추성 요인이 주로 작용하는 것으로 알려져 있다. 이러한 이갈이는 교모, 치경부 미세파절, 교근 비대, 교근 및 측두근의 통증, 턱관절의 통증 및 움직임의 제한, 치아 및 수복물 파절, 치수염, 외상성 교합 등을 유발 할 수 있고 특히 이악물기의 경우 협점막 압흔이나 협점막 백선 또는, 혀의 측면에 압흔 등을 유발한다. 이갈이의 정확한 진단을 위해 구강내 장치, 근전도, 수면다원검사 등을 이용하며 미국수면장애학회의 경우 이갈이의 임상 진단 기준을 제시하고 있다. 그러나 아직까지 이갈이의 명확한 원인이 밝혀져 있지 않기 때문에 치료법의 선택은 신중하여야 한다. 이갈이가 중등도 이상이고 임상 증상이나 징후를 유발하는 경우에 이갈이를 관리하기 위한 방법으로는 위험 요인의 조절, 구강내 장치, 보툴리눔 독소 주사, 약물 치료, 바이오피드백 등이 있으며 구강내 장치 요법이 현재로서 가장 합리적인 방법이다. 이갈이 치료와 교근비대에 대한 심미적인 개선을 같이 원하는 환자에서는 보툴리눔 독소 주사 요법이 이용될 수 있다.

• 대한소아치과학회지
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• 제45권1호
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• pp.65-74
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• 2018

본 연구의 목표는 측방 두부계측방사선 사진의 분석에 이용되는 소프트웨어의 소급성 확보와 측정값의 불확도를 계산하는 것이다. 또한 이를 이용해 소아에서 교정치료를 위한 계측값의 참고 표준을 얻기 위한 기반을 마련하고자 하였다. 교정치료를 위해 서울대학교 치과병원 소아치과에 내원한 6세에서 13세 사이 환아 중 1급 부정교합으로 진단 받은 환아 100명의 데이터를 수집하였다. 소급성 확보를 위해 방사선 촬영이 가능한 phantom 장비를 제작하였으며, 현재 사용중인 계측 소프트웨어를 이용하여 phantom 장비의 길이와 각도를 측정하여 소프트웨어의 교정값을 계산하였다. 불확도 계산을 위해 100명의 측방두부방사선영상 계측값과 반복측정에 의한 불확도와(A형 불확도) 최소분해능과 두부의 위치에 의한 불확도를(B형 불확도) 계산하였다. 이를 통해 합성표준불확도를 얻었으며 최종적으로 확장불확도를 계산하였다. 본 연구 결과 현재 사용중인 측방두부방사선사진 계측 프로그램이 높은 정확성과 신뢰도를 가지는 것을 확인하였다. 또한 교정값을 이용하여 계측값을 교정하였으며, 6 - 13세 한국인 소아에서의 교정계측치의 불확도를 계산하여 1급 부정교합 환아의 교정계측값의 95% 신뢰도를 가지는 분포범위를 제시하였다.