A mutation of UNCL, an inner nuclear membrane RNAbinding protein, has been found to eliminate mechanotransduction in Drosophila. UNCL is expressed in human periodontal tissue including in periodontal ligament (PDL) fibroblasts. However, it is unclear how a mechanical stimulus is translated into cellular responses in PDL fibroblasts. The aim of this study was to evaluate the effect of UNCl on mechanical stress related genes in PDL fibroblasts in response to mechanical stress. The mRNA of TGF-$\beta$, COX-2, and MMP-2 was up-regulated after UNCL inactivation in PDL fibroblasts under the compression force. Under the tensile force, inactivation of UNCL decreased the expression of Biglycan, RANKL, MMP-2, and TIMP-2 mRNAs while it increased the expression of TIMP-1. p38-MAPK was expressed in PDL fibroblasts under compression forces whereas phospho-ERK1/2, p65-NFkB, and c-fos were expressed under tension forces. The expression and phosphorylation of the mechanical stress related genes, kinases, and transcription factors were changed according to the types of stress. Furthermore, most of them were regulated by the inactivation of UNCL. This suggests that UNCL is involved in the regulation of mechanical stress related genes through the signaling pathway in PDL fibroblasts.
The purpose of this research is to provide an available basis for marketing strategy by defining the cause-effect relation between the service level of staff members in dental clinic and purchasing behavior of the customers. This study was done in 10 days from November 2, 2009 to November 11, 2009 and the total 172 copies were used for the analysis. As a result of the correlation analysis, a significant positive correlation among all the measured variables was found. As a result of the structural model analysis, I found that the fair service among the variables of the service level significantly affects the building of relationship and the hospital image. The building of relationship and the hospital image significantly affect the positive oral spread. The building of relationship significantly affects the repurchase intentions but the hospital image does not affects the repurchase intentions. To sum up the result of this study, I found that the fair service and the building of relationship with patients are important variables in order to attract new patients and maintain existing customers. I recommend that the hospital continues to motivate staffs through internal marketing and conduct regular trainings. It is necessary to have patients satisfied with broadening responsibility and authority and set marketing strategy for the relationship with patients.
With recent developments in digital dentistry, research on techniques and materials for three-dimensional (3D) printing is actively underway. We report the clinical applications and outcomes of 3D printing of temporary crowns fabricated with polylactic acid (PLA) using a fused deposition modeling (FDM) printer. Five participants were recruited from among patients scheduled to be treated with a single full-coverage crown at a dental clinic in a university medical center from June to August 2022. We used 3D-printed crowns fabricated with PLA using an FDM printer as temporary crowns and were assessed for discomfort, fracture, and dislodging. The 3D-printed temporary crowns were maintained without fracture, dislodging, or discomfort until the permanent prosthesis was ready. The average time required for printing the temporary crowns was approximately 7 minutes. The 3D printing of temporary crowns with PLA using an FDM printer is a convenient process for dentists. However, these crowns have some limitations, such as rough surface texture and translucency; therefore, the 3D printing process should be improved to produce better prostheses.
The aim of this study was to analyze the dental caries of chilren's deciduous teeth in relation to their mothers' socioeconomic factors and their oral health beliefs to increase the effect on children's oral health. One hundred seventy four children and their mothers were selected for the study. The children were 5 and 6 years old in children house in Kun-san, Korea. Research was conducted by oral examination, their mothers' socioeconomic factors and dental health belief model. The finding of analysis can be summaried as follows; In regard to the caries in deciduous teeth status, the five-year-old boy children's dft index was 3.39 and that of the girls of the same age was 2.76. The dft index of the boys of six was 3.86 and that of the girls of the same age was 3.27. The five-year-old boy children had the highest df rate(81.8%), and their dt rate was more than their ft rate. But for the six-year-old girl children, ft rate was higher than dt rate. For the five years old, the boy children's ft rate was significantly higher than that of the girls(p<0.05). Concerning the caries in deciduous teeth states by socioeconomic factors, their oral health status was significantly different according to mother employment and householder age. The df rate of the preschoolers with working mothers(84.7%) was significantly higher than that of those with nonworking mothers(66.7%)(p<0.05). The dft index of the group whose households were over forty was highest with 4.07, followed by the children of the households aged 35 to 39 with 3.83, those of the households aged 25 to 29 with 3.33, and those of the households aged 30 to 34 with 2.15. The difference between the groups was significant(p<0.05). As to the difference of maternal dental health beliefs by maternal socioeconomic factors, households educational background and whether to live with parents or parents-in-law under the same roof made a significant difference to maternal oral health beliefs. The mothers whose households were college graduates or better-educated were stronger in oral health susceptibility and seriousness(p<0.01, p<0.05). The salience was recognized more by those who lived with parents or parents-in-law than by the others who didn't(p<0.05). The dft index of the preschoolers was related to maternal dental health beliefs. That was lower when their mothers perceived dental health benefit better.
This study was conducted to provide basic data for improvement of the oral health management ability and the factors affecting oral health recognition and practice of 6th graders. The research subjects total 259 numbers of 6th grade students in two schools located in Changwon, it was investigated and analyzed with structured questionnaires. The collected data is analyzed by using IBM SPSS Statistics 19.0. The average oral health recognition score investigated were $3.19{\pm}0.41$, and $2.95{\pm}0.43$ for oral health practices. The oral health recognition was statistically significant differences by father's education (p<0.01), perceived oral health status (p<0.01), perceived grade (p<0.01), intention to attend oral health education (p<0.001). The oral health practices was statistically significant differences by father's education (p<0.01), perceived oral health status (p<0.001), perceived grade (p<0.05), parent's interest in child's toothbrushing (p<0.01), experience of oral health education (p<0.001), intention to attend oral health education (p<0.05). The factors that may improve the oral health recognition are in order of oral health practices, intention to attend oral health education, and parent's attention to child's tooth brushing. The factors that may improve the oral health practice was found to be in order of oral health recognition, parent's attention to child's tooth brushing, and perceived oral health status. As a result, in order to improve oral health management ability of 6th grade students, the surrounding environment, the attitude on oral care, the interest of oral, and the current disease status of oral health are required to be identified, then the oral health education program should be provided.
The purpose of this study is to analyze the experience of the parents who examined the first infant oral examination and to understand how to improve the practical oral examination business. In-depth interviews were held with 10 parents who did the first infant oral examination, and their children's age was less than 18 to 29 months. The following conclusions were obtained by deriving the concepts and categories of the recorded contents. First, the main reason for the unsatisfactory examination of this study was that it was formal. Parents were disappointed in the fact that they did not look at the mouth of the child at the same time as it was fast and they said because it is carried out free of charge, it is more formal than the examination for general dental treatment. Second, most of the participants questioned whether they should resume infant oral examination. Third, it appears that the tooth number or dental terminology in the result notice is difficult to understand. Fourth, the opinion on the improvement of the infant oral examinations was should provided that the oral health management information after examination and the direct oral health management method education at the examination. In addition, we identified the need for parents' oral health care education for infants. Therefore, it has been confirmed that in order for the infant oral examination and young children to be practically carried out, the problems should be improved by collecting opinions of the parents. Also it is necessary to search for efficient business management method through repeated research related to infant oral examination.
Kim, Byung-Jun;Kim, Ji-Hye;Ha, Won-Ho;Ahn, Jae-Hyun
Journal of dental hygiene science
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v.13
no.1
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pp.83-90
/
2013
The aim of this study was to evaluate the abrasive effect and cleaning power of toothpaste containing tetrasodium pyrophosphate and cellulose. The relative dentin abrasivity, cleaning power by modified Stookey method, dentin abrasivity of brushing after Cola treatment and consumer survey were investigated with control toothpaste containing dental type silica as an abrasive. The results obtained were as follows: 1. Experimental toothpaste hardly influenced dentin abrasivity, but control toothpaste had an effect on dentin abrasivity significantly (p<0.05). 2. There was no significant difference in cleaning power between experimental and control toothpaste (p>0.05). 3. Experimental toothpaste hardly influenced dentin abrasivity, despite 100 or 1,000 times of brushing after Cola treatment, but control toothpaste showed a big increase in dentin abrasivity as the number of brushing has been increased (p<0.05). 4. According to the consumer survey results, there was no difference between control and experimental toothpaste in the satisfaction rate of refreshing sensation, the satisfaction rate of the lasting effect of refreshing sensation and the overall satisfaction rate of the toothpaste (p>0.05). These results showed a possibility to make abrasive free toothpaste having cleaning power without dentin abrasivity.
This study conducted oral examinations and individual interviews on migrant multi-cultural family women in Daegu and measured their socio-demographic characters, oral health conditions and OHIP-14 in an aim to investigate the relevance between the oral health of migrant multi-cultural family women living in some big cities and their quality of life. Based on data finally collected from 189 women, the t-test, ANOVA and binary logistic regression analysis were conducted and the conclusions are as follows: The average number of decayed teeth was 2.23, loss teeth was 1.48, and treated teeth was 5.58. Women from the Philippines had more number of loss teeth than those from other countries, and women from China relatively had a small number of filled permanent teeth. The quality of life related to oral health was found to be poor in proportion to the number of loss teeth. A comparison of life quality related to oral health depending on loss teeth showed that life quality related to oral health was lowest in the areas of mental discomfort, physical ability decrease, mental ability decrease, social ability decrease and social disadvantage. Life quality related to oral health was found to be low in proportion to the number of permanent teeth with decay experience and poor monthly household income, which shows that the number of permanent teeth with decay experience and monthly income are mostly related to life quality related to oral health. As migrant multi-cultural family women's life quality related to oral health is low in proportion to the number of loss teeth and decayed teeth, it needs to develop a program to improve their oral healthrelated life quality and conduct follow-up research to verify its effect.
The most frequently encountered problems at fixture-implantation sites are lack of adequate bone and proximity to anatomic structures. It is generally accepted that growth factors play an essential role in the healing process and tissue formation, and they have become the focus of grafting materials research. The granules in platelets contain high concentrations of various growth factors. In particular, platelet-rich fibrin (PRF) is a second-generation platelet concentrate that allows the production of fibrin membranes enriched with platelets and growth factors from an anticoagulant-free blood harvest. This study investigated the in vitro effects of PRF on osteoblasts, in terms of the key cellular functions, and especially the effects on two growth factors, the homodimer of platelet-derived growth factor subunit B (BPDGF-BB) and transforming growth factor (TGF)-${\beta}1$, which are associated with wound healing and regeneration (i.e., proliferation and differentiation). The following parameters were investigated: PDGF-BB and TGF-${\beta}1$ levels in PRF, cell viability, alkaline phosphatase (ALP) activity, type 1 collagen synthesis, and the expressions of osteoblast differentiation markers (ALP and runt-related transcription factor 2) and bone matrix proteins (type 1 collagen). The release of autologous growth factors from PRF was maintained for a reasonable period of time, and exerted positive effects on the proliferation and differentiation of osteoblasts. The use of PRF thus appears to be a promising method for enhancing bone healing and remodeling.
Journal of the Korea Academia-Industrial cooperation Society
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v.18
no.1
/
pp.388-394
/
2017
The purpose of this study was to determine the mediating effects of stress associated with university life and the stress response of university students' resilience towards the negative emotions of health department students. As a research method, 284 students in the health department of Gyeongsangnamdo were surveyed. Data were analyzed in terms of frequency, correlation and regression using SPSS 22.0 program. The results of the study were as follows. The mean score of resilience towards negative emotions among students in the health department was 4.49, while stress associated with university life was 2.74. As a result of the correlation analysis among resilience towards negative emotion, stress response and stress associated with university life, the negative emotion was found to have a negative correlation with the stress associated with university life and the stress response. Resilience towards negative emotions was found to reduce the stress associated with university life by mitigating the stress response. Therefore, in this study, resilience appears to affect the stress associated with university life and the students' response to it. Therefore, for students in the health department who are exposed to stress associated with university life, the resilience towards negative emotions may be a way of alleviating the stress response.
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