• Nuclear Engineering and Technology
• /
• v.48 no.3
• /
• pp.684-701
• /
• 2016

The Gaussian process model (GPM) is a flexible surrogate model that can be used for nonparametric regression for multivariate problems. A unique feature of the GPM is that a prediction variance is automatically provided with the regression function. In this paper, we estimate the safety margin of a nuclear power plant by performing regression on the output of best-estimate simulations of a large-break loss-of-coolant accident with sampling of safety system configuration, sequence timing, technical specifications, and thermal hydraulic parameter uncertainties. The key aspect of our approach is that the GPM regression is only performed on the dominant input variables, the safety injection flow rate and the delay time for AC powered pumps to start representing sequence timing uncertainty, providing a predictive model for the peak clad temperature during a reflood phase. Other uncertainties are interpreted as contributors to the measurement noise of the code output and are implicitly treated in the GPM in the noise variance term, providing local uncertainty bounds for the peak clad temperature. We discuss the applicability of the foregoing method to reduce the use of conservative assumptions in best estimate plus uncertainty (BEPU) and Level 1 probabilistic safety assessment (PSA) success criteria definitions while dealing with a large number of uncertainties.

• Clinical and Experimental Pediatrics
• /
• v.59 no.sup1
• /
• pp.10-13
• /
• 2016

Chromosome 11q13 deletion syndrome has been previously reported as either otodental syndrome or oculo-oto-dental syndrome. The otodental syndrome is characterized by dental abnormalities and high-frequency sensorineural hearing loss, and by ocular coloboma in some cases. The underlying genetic defect causing otodental syndrome is a hemizygous microdeletion involving the FGF3 gene on chromosome 11q13.3. Recently, a new form of severe deafness, microtia (small ear) and small teeth, without the appearance of eye abnormalities, was also reported. In this report, we describe a 1-year-old girl presenting with ptosis of the left upper eyelid, right auricular deformity, high-arched palate, delayed dentition, simian line on the right hand, microcephaly, and developmental delay. In this patient, we identified a deletion in the chromosome 11q13.2-q13.3 (2.75 Mb) region by using an array-comparative genomic hybridization analysis. The deletion in chromosome 11q13 results in a syndrome characterized by variable clinical manifestations. Some of these manifestations involve craniofacial dysmorphology and require a functional workup for hearing, ophthalmic examinations, and long-term dental care.

• Journal of Korean Academy of Nursing
• /
• v.27 no.2
• /
• pp.329-340
• /
• 1997

Resourcefulness was analyzed by Walker and Avant's method to make a theoretical framework for nursing. Also, the appropriate Korean terminology was identified.“Resourcefulness”means the ability to use internal and external resources to eliminate or to control stress. '자원동원성' is chosen to be the most appropriate term to reflect the concept of resourcefulness. Upon the concept analysis, availability, controllability, confidence, and self-instruction were identified as the defining characteristics of resourcefulness. Contrary to other work, "availability" means the ability to use the social resources as well as the internal cognitive-behavioral resources. “Controllability” means the ability to delay or control immediate gratification of one's needs or to divert one's own mood in order to solve problem. "Confidence" is the self-efficacy belief in one's control ability. "Self-instruction" is the cognitive ability to instruct oneself positively. Resourcefulness is learned by active experience, vicarious experience, and formal or informal instruction, and it is cued in the presence of a stressful situation or a need for change. As a result of the use of resourcefulness, the target behavior performed immediately and ultimately improve the quality of life or adaptation. Therefore, it is necessary to develop the instrument including the defining attributes identified in this study. Also, it is necessary to simultaneously analyze the related concepts of self-efficacy, self-control, and self-regulation for appropriate use.

• Korean System Dynamics Review
• /
• v.17 no.2
• /
• pp.5-32
• /
• 2016

Purpose of this paper is to review series of Limits to Growth studies from its original Rome Club Report published in 1972 to the most recent one in 2012 by Jorgen Randers and finds its implications on concept and strategy of sustainable development. For this purpose first, this paper reviewed series of Limits to Growth studies in details with focus on scenarios used in simulation of world model. Second, response to the original Limit to Growth was reviewed and to see validity of its scenario based simulations, simulated results of interest variables and actual historical data up to the year 2010 was compared. Third, structure and key arguments in both studies, Limit to Growth studies and Our Common Future was explained and compared. Finally, implications of the Limit to Growth studies on concept and strategy for sustainable development was discussed. Based on the comparison, this paper argued that even if the term sustainable development was not used in the Limit to Growth at all, concept and strategies for sustainable development implied in the Limit to Growth are more clear and specific than those of Our Common Future. Since Limit to Growth studies were simulation based ones that produce detailed behaviors on interest variables, it clarifies more clearly the abstract concept of sustainable development and thus, provides specific guidelines for the direction of sustainable policy which has been suffering long from vagueness of concept of sustainable development.

• Journal of The Korean Society of Inherited Metabolic disease
• /
• v.13 no.1
• /
• pp.30-36
• /
• 2013

6-pyruvoyltetrahydropterin synthase (PTPS) deficiency is autosomal recessive disorder and the most common type of tetrahydrobiopterin (BH4) deficiency. It is caused by deficiency of PTPS, a cofactor involved in the biosynthesis of BH4 from guanosine triphosphate (GTP). Unlike classical phenylketonuria, which needs restriction of dietary phenylalanine for whole life, BH4 deficiency is treated by tetrahydrobiopterin, levodopa, and 5-hydroxytryptophan replacement. So it is important to make accurate diagnosis and initiate treatment as soon as possible for a better prognosis. There is no retrospective study of Korean patients undergoing long-term treatment for PTPS deficiency. We report 9 Korean patients with PTPS deficiency and their laboratory findings including BH4 loading tests, urine pterin tests, genotypes, dihydropteridine reductase (DHPR) activities and clinical manifestations including medication and developmental delay existence.

• Journal of the Institute of Electronics Engineers of Korea SC
• /
• v.42 no.6
• /
• pp.1-8
• /
• 2005

The calculation of parameters of a process model is modified to find better sliding mode controller for a process. A design method by Camacho has such problems as chattering and overshoot due to the Taylor the approximation errors for the time delay term of the first order model. In this paper, a new design technique for a sliding mode controller is proposed by introducing the modified Pade approximation considering the weight factor. With the proposed method, the process response can be directly used to estimate the system parameters without any numerical processing.

• Journal of the Institute of Electronics and Information Engineers
• /
• v.52 no.6
• /
• pp.3-9
• /
• 2015

We investigate rate scheduling and power allocation problem for a delay constrained CDMA systems. Specifically, we determine an energy efficient scheduling policy, while each user maintains the short term (n time slots) average throughput. We consider a multirate CDMA system where multirate is achieved by multiple codes. Each code can be interpreted as a virtual user. The aim is to schedule the virtual users into each time slot, such that the sum of transmit energy in n time slots is minimized. We then show that the total energy minimization problem can be solved by a shortest path algorithm. We compare the performance of the optimum scheduling with that of TDMA-type scheduling.

• The Bulletin of The Korean Astronomical Society
• /
• v.41 no.1
• /
• pp.70.4-71
• /
• 2016

The links between super-massive black hole masses and their host galaxy properties are observed, indicating that black hole growth and host galaxy evolution are closely related. Reverberation mapping, which uses the time delay from the central black hole to broad line regions, is one of the best methods to estimate masses of black holes of active galactic nuclei (AGNs). However, only masses of about 50 black holes have been determined in reverberation mapping studies so far, and most of them are limited to optical luminosities below 10^45 erg/s due to the challenges of long-term time domain observations in both photometry and spectroscopy. In this project, we expand reverberation mapping samples to higher luminosities of > 10^44.5 erg/s at 0.1 < z < 0.35, that have expected time lags of 40 - 250 light days. Photometric (using LOAO 1-m and MDM 1.3-m) and spectroscopic (using MDM 2.4-m and Lick 3-m) monitoring campaigns are being conducted for a 3 year duration and 20 day cadence. Precedent photometric observations in 2015B show some targets with variability and follow-up spectroscopic observations are on-going. In this presentation, we introduce our project, present reverberation mapping simulation results, and preliminary results on photometry. These reverberation mapping masses of relatively high luminous AGNs will provide a strong constraint on black hole mass calibration, e.g., the single-epoch mass estimation.

• Fashion & Textile Research Journal
• /
• v.22 no.4
• /
• pp.481-494
• /
• 2020

This study examined consumer perceptions and consumer responses of Halal cosmetics and compared them with vegan cosmetics, which is a term similarly used. Twitter API of Python 3.7 was used to collect the keywords '#halalcosmetics' and '#vegancosmetics'. First, the main perception of consumers on Halal cosmetics focused on the original concept, image, expected efficacy, and factors to consider before purchase, religious keywords, labels and packaging for Halal cosmetics. Second, the main consumer perception of vegan cosmetics was the product concept, expected efficacy, factors to consider before purchase, related vegan industry, image, and vegan cosmetic components. Third, the consumer perceptions of Halal cosmetics and vegan cosmetics were similar in multiple ways, and both concepts included the Cruelty-free concept. Fourth, consumer satisfaction factors included cosmetics color, brand's consumer service, efficacy, smell, packaging design, reasonable price, effects, and formulation of cosmetics as well as satisfaction with Halal certification, and satisfaction of Vegan consumers. Consumer dissatisfaction factors included smell, flavor, delay in shipping, dissatisfaction with formulation, discrepancy between actual color and computer screen, concern and distrust about the use of prohibited ingredients for Halal products. This study examined consumer perceptions and reactions to Halal and vegan cosmetics to create basic knowledge for niche markets that are emerging as an ethical beauty consumption trend.

• Industrial Engineering and Management Systems
• /
• v.15 no.3
• /
• pp.259-267
• /
• 2016

In Wireless Sensor Network, various routing protocols were employed by our Research and Development community to improve the energy efficiency of a network as well as to control the traffic by considering the terms, i.e. Packet delivery rate, the average end-to-end delay, network routing load, average throughput, and total energy consumption. While maintaining network connectivity for a long-term duration, it's necessary that routing protocol must perform in an efficient way. As we discussed Optimized Link State Routing protocol between all of them, we find out that this protocol performs well in the large and dense networks, but with the decrease in network size then scalability of the network decreases. Whenever a link breakage is encountered, OLSR is not able to periodically update its routing table which may create a redundancy problem. To resolve this issue in the OLSR problem of redundancy and predict link breakage, an enhanced protocol, i.e. S-OLSR (More Scalable OLSR) protocol has been proposed. At the end, a comparison among different existing protocols, i.e. DSR, AODV, OLSR with the proposed protocol, i.e. S-OLSR is drawn by using the NS-2 simulator.