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Survival and Problems after Repair of Tetralogy of Fallot (Fallot 4징 교정수술후의 생존 및 문제점)

  • 손세정;한재진;이영탁;김성호
    • Journal of Chest Surgery
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    • v.32 no.3
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    • pp.237-248
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    • 1999
  • Background: The late results of repair of tetralogy of Fallot(TOF) are favorable in most patients. Some portion of the patients with tetralogy, however, require reoperation for residual lesions or result in late death. The outcome of patients after tetralogy repair performed during the past 13 years was studied, with an emphasis on postrepair survival and problems including reoperations. Material and Method: A retrospective review of clinical, echocardiographic and catheterization data was performed in 569 of 775 patients with TOF who underwent corrective repair between 1983 and 1995 at Sejong General Hospital, Buchon, Korea. Result: Of 28(4.9%) early deaths(defined as 30 days postrepair), 12 deaths(42.9%) were <1 year of age, with an operative mortality of 15.4%. The surviving 541 patients(age 2.8 months to 43.4 years, median 23 months) have been followed up from 1 month to 12.6 years(median 35 months) postoperatively. Most patients were in good functional class and had normal right ventricular(RV) function. Postrepair results were compared between the transatrial-transpulmonary approach and the conventional right ventriculotomy. The former technique provided a lesser incidence of significant pulmonary regurgitation(P<0.001) and alesser degree of RV dysfunction(P<0.05) compared with those in the latter. There were 10(1.8%) late deaths during the follow-up period and 6 of the deaths were directly related to reoperation or ventricular dysfunction. The 10-year actuarial survival rate was 96.7%. There were 44 reoperations(8.1%) in 39 patients(7.2%), with an operative mortality of 10.3%. The main indications or reoperation included residual ventricular septal defect(VSD) (n=6), pulmonary stenosis(PS) (n=11), VSD with PS(n=17), pulmonary regurgitation(n=7), and tricuspid regurgitation(n=2). The 5- and 10-year freedom from reoperation were 89.4% and 76.1%, respectively. Conclusion: Although the majority of patients with repaired TOF are clinically well, with a high rate of survival, approximately 7% of patients have residual lesions that require surgical therapy. Therefore, the timely and meticulous corrective repair is mandatory to avoid reoperation, and continued close surveillance is also needed for the early detection of residual problems.

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Results of Radiotherapy in Hypopharyngeal Cancer (하인두암의 방사선치료)

  • Shin Byung Chul;Yum Ha Yong;Moon Chang Woo;Jeong Tae Sik
    • Radiation Oncology Journal
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    • v.20 no.3
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    • pp.206-214
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    • 2002
  • Purpose : The aim of this study was to assess the effectiveness, survival rate and complications of radiation therapy and chemoradiation treatment in hypopharyngeal cancer. Methods and Materials : From January 1984 to December 1999, 56 patients who had hypopharyngeal carcinoma treated with curative radiation therapy were retrospectively studied. Twenty four patients $(42.9\%)$ were treated with radiation therapy alone (Group I) and $32\;(57.1\%)$ treated with a combination of chemotherapy and radiation (Group II). Total radiation dose ranged from 40.5 to 83. 5 Gy (median 67.9 Gy). Radiotherapy was given with conventional technique in 9 patients $(16.4\%)$, with hyperfractionation I ($1.15\~1.2$ Gy/fr., BID) in 26 $(47.2\%)$, hyperfractionation II (1.35 Gy/fr., BID) in 18 $(32.7\%)$, and accelerated fractionation (1.6 Gy/fr., BID) in 2 $(3.6\%)$. In chemotherapy, 5-FU ($1,000\;mg/m^2$ daily for 5 consecutive days) and cisplatin ($100\;mg/m^2$ on day 1) were administered in a cycle of 3 weeks interval, and a total of 1 to 3 cycles (average 2..3 cycles) were given prior to radiation therapy. Follow up duration was $1\~195$ months (median 28 months). Results : Overall 2 and 5 year survival rates were $40.6\%\;and\;27.6\%;\;50.0\%\;and\;30.0\%$ in Group I, and $36.4\%\;and\;26.3\%$ in Group II, respectively. Complete local control rates in Group I and II were $70.0\%\;and\;67.7\%$, respectively. The response to radiotherapy and nodal stage were statistically significant prognostic factors. The complication rate was increased in Group II and was decreased in hyperfractionation. Conclusion : The response to radiotherapy and nodal stage were valid factors to indicate the degree of control over the hypopharyngeal cancer. The induction cisplatin, 5-Fu chemotherapy was not valid in terms of local control rate and survival rate, but did contribute to an increased complication rate. The use of hyperfractionation was valid to reduce the late radiation complications.

Growth and Lodging of Paddy Rice as Affected by Paclobutrazol Application under the Different Level of Nitrogen Fertilizer (질소수준(窒素水準)이 다른 조건하(條件下)에서 Paclobutrazol 처리(處理)가 수도생장(水稻生長) 및 도복(倒伏)에 미치는 영향(影響))

  • Im, I.B.;Lee, S.Y.;Lim, M.S.
    • Korean Journal of Weed Science
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    • v.7 no.2
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    • pp.171-178
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    • 1987
  • This study was conducted to examine the possibility of complete lodging. prevention, the growth and yield of the paddy rice plant by paciobutrazol 0.6%G application at 15 days before heading under the several levels (0, 5, 10, 15, 20, 25, 30, 35, 40, 45 kg/10a) of nitrogen fertilizer in 1986. Culm length was shortened 10-15% by paclobutrazol application. The shortened rate of internode was very extreme on the 3rd and 4th internode in paclobutrazol application. Moment the height of center gravity and lodging index turned higher with increasing nitrogen fertilizer, on the other hand, those of paclobutrazol application were smaller than control. Lodging degree (0~4) was 1~3 above 25kg/10a level of nitrogen fertilizer in control, however, no more than 1 at 45kg/10a level of nitrogen fertilizer in paclobutrazol application. Ripened grain ratio and grain weight of paclobutrazol application were larger than those of control. Yield increased more 15-26% in paclobutrazol application than control. The nitrogen level of maximum yield was about 25kg/10a in control, but was 31kg/10a in paclobutrazol application.

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Degree of Retrogradation of Non-Waxy and Waxy Rice Cakes during Storage determined by DSC and Enzymatic Methods (DSC와 효소법을 이용한 멥쌀 밑 찹쌀떡의 노화도에 관한 연구)

  • 김창순
    • Korean journal of food and cookery science
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    • v.12 no.2
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    • pp.186-192
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    • 1996
  • Retrogradation of non-waxy rice (NWR) and waxy rice (WR) cakes (45% moisture) stored at 5$^{\circ}C$, $25^{\circ}C$ and -2$0^{\circ}C$ was studied by differential scanning calorimetry (DSC) and enzymatic ($\beta$-amylase-puuulanase) method. With DSC, endotherms did not appear with rice cakes stored at room ($25^{\circ}C$) and deep freezing (-2$0^{\circ}C$) temperatures but did with samples stored at low temperature (5$^{\circ}C$), showing accelerated retrogradation by low temperature. Onset temperature (To) and peak temperature (Tp) did not change under 14 days at 5$^{\circ}C$ but enthalpy values ($\Delta$H) increased rapidly within one day and increased steadily until 5th day of storage, then equilibrated. Higher $\Delta$H were obtained with WR cakes than NWR cakes. It was suggested that more amylopectin recrystallization occured with WR than NWR. Degrees of gelatinization of rice cakes determined by enzymatic method increased in the following order: 5$^{\circ}C$ < $25^{\circ}C$ < -2$0^{\circ}C$. In contrast with DSC results, dogrees of gelatinization of NWR cakes, were relatively lower than that of WR cakes. However, increased retrogradation extents (melting enthalpies) caused reduced enzyme susceptibilities to $\beta$-amylase-pullulanase system, among NWR or WR cakes stored at 5$^{\circ}C$. The degrees of retrogradation of rice cakes stored at 5$^{\circ}C$ were higher than those stored at $25^{\circ}C$ and -2$0^{\circ}C$ without regard to the kind of rice. The higher sensitivity of the enzymatic method was obtained than that of DSC method when the degrees of retrogradation of rice cakes were determined during storage under this experiment conditions.

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Site Competition of Ca2+ and Cs+ Ions in the Framework of Zeolite Y (Si/Al = 1.56) and Their Crystallographic Studies (제올라이트 Y (Si/Al = 1.56) 골격 내의 Ca2+과 Cs+ 이온의 자리 경쟁 및 그들의 결정학적 연구)

  • Kim, Hu Sik;Park, Jong Sam;Lim, Woo Taik
    • Journal of the Mineralogical Society of Korea
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    • v.31 no.4
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    • pp.235-248
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    • 2018
  • The present work was performed in order to study the effect of competing cation of $Ca^{2+}$ ion on ion exchange of $Cs^+$ on zeolite Y (Si/Al = 1.56). Three single-crystals of fully dehydrated and partially $Cs^+$-exchanged zeolites Y (Si/Al = 1.56) were prepared by the flow method using mixed ion-exchange solutions. The $CsNO_3:Ca(NO_3)_2$ molar ratios of the ion exchange solution were 1 : 1 (crystal 1), 1 : 100 (crystal 2), and 1 : 250 (crystal 3) with a total concentration of 0.05 M. The single-crystals were then vacuum dehydrated at 723 K and $1{\times}10^{-4}Pa$ for 2 days. The structures of the crystals were determined by single-crystal synchrotron X-ray diffraction technique in the cubic space group $Fd{\bar{3}}m$, at 100(1) K. The unit-cell formulas of crystals 1, 2, and 3 were ${\mid}Cs_{21}Ca_{27}{\mid}[Si_{117}Al_{75}O_{384}]-FAU$, ${\mid}Cs_2Ca_{36.5}{\mid}[Si_{117}Al_{75}O_{384}]-FAU$, and ${\mid}Cs_1Ca_{37}{\mid}[Si_{117}Al_{75}O_{384}]-FAU$, respectively. In all three crystals, the $Ca^{2+}$ ions preferred to occupy site I in the D6Rs, with the remainder occupying sites I', II', and II. On the other hand, the significant differences in the fractional distribution of $Cs^+$ ions are observed depending on the intial $Cs^+$ concentrations in given ion exchange solution. In Crystal 1, $Cs^+$ ion are located at sites II', II, III, and III', and in crystal 2, at sites II, IIIa, and IIIb. In crystal 3, $Cs^+$ ions are only located at sites IIIa and IIIb. The degree of $Cs^+$ ion exchange decreased sharply from 28.0 to 2.7 to 1.3 % as the initial $Ca^{2+}$ concentration increases and the $Cs^+$ content decreases.

Thermal Effects on the Development, Fecundity and Life Table Parameters of Aphis craccivora Koch (Hemiptera: Aphididae) on Yardlong Bean (Vigna unguiculata subsp. sesquipedalis (L.)) (갓끈동부콩에서 아카시아진딧물[Aphis craccivora Koch (Hemiptera: Aphididae)]의 온도발육, 성충 수명과 산란 및 생명표분석)

  • Cho, Jum Rae;Kim, Jeong-Hwan;Choi, Byeong-Ryeol;Seo, Bo-Yoon;Kim, Kwang-Ho;Ji, Chang Woo;Park, Chang-Gyu;Ahn, Jeong Joon
    • Korean journal of applied entomology
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    • v.57 no.4
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    • pp.261-269
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    • 2018
  • The cowpea aphid Aphis craccivora Koch (Hemiptera: Aphididae) is a polyphagous species with a worldwide distribution. We investigated the temperature effects on development periods of nymphs, and the longevity and fecundity of apterous female of A. craccivora. The study was conducted at six constant temperatures of 10.0, 15.0, 20.0, 25, 30.0, and $32.5^{\circ}C$. A. craccivora developed successfully from nymph to adult stage at all temperatures subjected. The developmental rate of A. craccivora increased as temperature increased. The lower developmental threshold (LT) and thermal constant (K) of A. craccivora nymph stage were estimated by linear regression as $5.3^{\circ}C$ and 128.4 degree-days (DD), respectively. Lower and higher threshold temperatures (TL, TH and TH-TL, respectively) were calculated by the Sharpe_Schoolfield_Ikemoto (SSI) model as $17.0^{\circ}C$, $34.6^{\circ}C$ and $17.5^{\circ}C$. Developmental completion of nymph stages was described using a three-parameter Weibull function. Life table parameters were estimated. The intrinsic rate of increase was highest at $25^{\circ}C$, while the net reproductive rate was highest at $20^{\circ}C$. Biological characteristics of A. craccivora populations from different geographic areas were discussed.

Effects of Wind Net Shading and Sprinkling on Growing Conditions and Fruit Quality in 'Hongro' and 'Fuji' Apple Fruits (방풍망 차광시설 및 미세살수 처리가 '홍로' 및 '후지' 사과나무의 생육환경 및 과실 품질에 미치는 영향)

  • Kang, Kyeong-Jin;Seo, Jeong-Hak;Yoon, Hong-Ki;Seo, Jeong-Seok;Choi, Taek-Yong;Chun, Jong-Pil
    • Journal of Bio-Environment Control
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    • v.28 no.2
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    • pp.126-133
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    • 2019
  • In recent years, the deterioration of fruit quality caused by poor coloration and sunburn disorder has become serious problems in apple market, which is a result of the increase of surface temperature due to the abnormal temperature increase during summer season. This study was conducted to investigate the effect of wind net shading and fine water spray using sprinkler on fruit coloration, sunburn damage and overall fruit quality of 'Fuji' and 'Hongro' apples. Fifteen sprinklers (7L/hr) were installed at the orchard of the Chungcheongnam-do Agricultural Research and Extension Services, located in Sinam-myeon Chungcheongnam-do Korea, at a height of 3m above the apple tree of $1.5m{\times}3.5m$ north-south direction. Fine water spraying treatment was divided into day time spray (10:00 am to 6:00 pm) and all day spray (10:00 am to 10:00 pm) from early July to 10 days before harvest in 2017 and 2018 season, respectively. Temperature of the surface of apple fruit, characteristic of fruit, and degree of sunburn damage were investigated. In 'Fuji', the fruit surface temperature checked at 2 pm on August 10 was decreased considerably in the day time spray ($35.6^{\circ}C$) and wind net ($39.0^{\circ}C$) when compared with the untreated control ($44.4^{\circ}C$). Similarly, the fruit surface temperature also decreased considerably in the all day spray ($35.1^{\circ}C$) and wind net ($36.9^{\circ}C$) treatments when compared with the untreated control ($46.5^{\circ}C$) in 'Hongro' apples. The incidence of sunburn disorder was significantly decreased with day time spray (5.0%), all day spray (5.8%) and wind net (7.0%) when compared with untreated control (23.4%) in 'Fuji' apples. As a results, the treatment of fine water spray and wind net consequently showed 26% and 34% increase of redness ($a^*$) value in the skin color difference, respectively, in 'Fuji' apples.

Estimation of the Optimal Periods for Planting and Felling Larix kaempferi Based on the Period of Its Cambial Activity (형성층 활동 기간을 활용한 일본잎갈나무 식재 및 벌채 적기 추정)

  • YOO, Hye-Ji;JU, Jeong-Deuk;PARK, Jun-Hui;SHIN, Chang-Seob;EOM, Chang-Deuk;SEO, Jeong-Wook
    • Journal of the Korean Wood Science and Technology
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    • v.49 no.5
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    • pp.399-415
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    • 2021
  • This study was conducted to suggest the optimal periods for planting and felling Larix kaempferi tree by monitoring its cambial activity period. In addition, the heat summation to induce the cambial activity of Larix kaempferi was investigated. The study sites were at Mt. Worak and Mt. Midong. After selecting 5 trees at Mt. Worak and Mt. Midong, the cambium samples were collected using a mini trephor with 2 mm diameter from April 7 to October 6, 2017 at Mt. Worak, and from April 7 to September 29, 2017 at Mt. Midong. After the collected cambium samples were embedded in PEG2000, transverse thin sections with a thickness of 10 to 15 ㎛ were prepared using a microtome. One Larix kaempferi sample from each site, Mt. Worak and Mt. Midong, in which the accurate monitoring of cambial activity was impossible due to the formation of traumatic resin canal, was excluded from the study. The observation of the initiation date of cambial activity under a light microscopy revealed that 2 specimens from Mt. Worak and 3 from Mt. Midong showed the initiation on April 28. The remaining 2 specimens of Mt. Worak and 1 specimen of Mt. Midong were initiated on May 4, which was a week later than the others. The heat summation that induced the initiation of cambial activity was 196.4-271.8 at Mt. Worak and 204.7-277.3 at Mt. Midong, which was similar. The termination of cambial activity occurred between August 4 and 25 at Mt. Worak, and between August 4 and September 1 at Mt. Midong. Based on the above results, it was found that the optimal planting period for Larix kaempferi in Mt. Worak and Mt. Midong was before April, about a month before the cambium activity, and the felling period was from October when the cambial activity was completely terminated.

Changes in Characteristics of Semi-cured Pig Manure Liquid Fertilizer according to the Storage Duration and Aeration (반부숙상태 돈분뇨 액비의 저장기간 및 폭기여부에 따른 특성 변화)

  • Jeong, Kwang-Hwa;Park, Hoe-Man;Lee, Dong-Jun;Kim, Jung-Kon;Kim, Hyunjong
    • Journal of the Korea Organic Resources Recycling Association
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    • v.30 no.4
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    • pp.109-122
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    • 2022
  • Currently, most of the pig manure generated from pig farms in Korea is in the form of a slurry with a moisture content of about 97%. Pig manure slurry is a mixture of pig manure and cleaning water in the pig house. In this study, changes in properties of pig manure liquid fertilizer according to whether air was supplied or not and with the passage of storage period were analyzed for 120 days. During the experimental period, the degree of maturity of the pig manure liquid fertilizer was higher in the experimental closed batch reactors supplied with air than in the same type reactors not supplied with air. As the liquid fertilizer storage period elapsed, there was a tendency that liquid fertilizer was converted to a state of complete maturity. In the batch reactor in which air was supplied, the moisture content of pig manure slurry, which had a moisture content of 97.90%, was reduced to 96.82% at the end of the experiment. On the other hand, the moisture content in the reactor without air was reduced to 97.33%. The pH of the liquid fertilizer, which was 8.82 at the start of the experiment, changed to 7.57 in the reactor with air supplied and 8.75 in the reactor without air at the completion of the experiment. The nitrogen content in the liquid fertilizer was 0.198 mg/L on average at the start of the experiment and it was lowered to 0.076 mg/L in the air supplied reactor at the end of the experiment. On the other hand, the nitrogen content of the liquid fertilizer was lowered to 0.121 mg/L in the reactor to which air was not supplied. The phosphoric acid (P2O5) concentration in the liquid decreased higher in the liquid fertilizer filled in the reactor without air than the liquid fertilizer filled in the reactor with air supplied as the storage period elapsed. Considering the experimental results, it is considered that the quality of pig manure liquid fertilizer is improved when air is supplied to pig manure slurry and the storage period of pig manure slurry is longer.

Growth at Heading Stage of Rice Affected by Temperature and Assessment of the Target Growth Applicable to North Korea for Breeding in South Korea (기온에 따른 벼 출수기 생육 반응 및 남한에서 북한 적응 품종 육성을 위한 출수기 목표 생장량 추정)

  • Yang, Woonho;Choi, Jong-Seo;Lee, Dae-Woo;Kang, Shingu;Lee, Seuk-ki;Chae, Mi-Jin
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.23 no.2
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    • pp.108-121
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    • 2021
  • Field studies at Suwon, Cheorwon, and Jinbu were carried out to determine the relationship between mean temperature from transplanting to heading (MT) and growth at heading stage of rice. P lant height (P H) and dry weight (DW) at heading stage were significantly correlated with MT, showing second degree polynomials. The optimal temperatures for PH and DW were 23.2 ℃ and 22.8 ℃, respectively. Little differences in rice growth among soils collected from the experimental sites and the temperature-response in a phytotron study supported that MT was the main determinant of the growth shown in the field study. Though number of days to heading increased as MT decreased, cumulative temperatures (CT) affected by sites and MT for given varieties were fairly constant. When applying specific CT for each of the varieties to the temperature in North Korea, (1) five regions (Kaesong, Haeju, Sariwon, Nampo, Pyongyang) were suitable for early to mid-maturing varieties and (2) 14 regions (Yongyon, Singye, Anju, Kusong, Sinuiju, Changjon, Wonsan, Hamhung, Pyonggang, Yangdok, Huichon, Supung, Sinpo, Kanggye) were suitable only for early-maturing varieties. In (1) regions, the similar extent of growth with that in Suwon could be achieved when mid-maturing varieties grown in Suwon are cultivated. Among (2) regions, early-maturing varieties are expected to demonstrate the similar extent of growth with that in Cheorwon in 9 regions except Hamhung, Kanggye, Pyonggang, Yangdok, and Sinpo. For Hamhung and Kanggye, the target PH was assessed as 4cm higher than that shown in Cheorwon. P lant height of 8-14cm and DW of 2-4g per hill greater than those shown in Cheorwon were the target growth for P yonggang, Yangdok, and Sinpo to attain the similar amount of growth with that in Cheorwon. It is suggested that rice varieties for North Korea could be bred by adjusting the target growth at the breeding sites in South Korea.