• Title/Summary/Keyword: deformability

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Measurement of red cell deformability and whole blood viscosity using laser-diffraction slit rheometer

  • Sehyun Shin;Yunhee Ku;Park, Myung-Su;Suh, Jang-Soo
    • Korea-Australia Rheology Journal
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    • v.16 no.2
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    • pp.85-90
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    • 2004
  • The present study investigated the deformability of red blood cells (RBC) and its effect on whole blood viscosity using a laser-diffraction slit-rheometer (LDSR). The LDSR has been recently developed with significant advances in laser-diffractometry design, operation and data analysis. While shear stress levels in a slit flow are continuously decreasing, both the deformation of red blood cells and the shear stress were simultaneously measured. Additionally, the viscosity of whole blood was measured using the LDSR. The present study found that the whole blood viscosity is strongly dependent on the RBC deformability. The less deformable the RBCs are, the higher the blood viscosity is.

Effect of Transverse Reinforcement Ratios to Deformability of Hollow Sectional Columns having 50% Lap-spliced Longitudinal Bars (주철근의 1/2이 겹침이음된 중공단면기둥의 횡철근비에 따른 변형성능)

  • Moon, Chang-Hyun;Sun, Chang-Ho;Jeong, Hyeok-Chang;Kim, Ick-Hyun;Lee, Jong-Seok
    • Proceedings of the Korea Concrete Institute Conference
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    • 2006.11a
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    • pp.49-52
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    • 2006
  • Unlike columns having lap-spliced longitudinal bars in plastic hinge regions columns having 50% of lap-spliced bars were reported to have good ductilities relatively. But the effect of transverse reinforcements to deformability is not clearly confirmed. In this study scale models with different confinements were tested under various loading conditions. It was confirmed that deformability was increased with increase of transverse reinforcement ratio regardless of loading conditions and 75% of confinement yielded the satisfactory deformability.

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CHANGE OF BLOOD VISCOSITY AND DEFORMABILITY IN ORAL SQUAMOUS CELL CARCINOMA PATIENTS (구강편평세포암종 환자에서의 혈액 점도와 혈액 변형성 변화에 대한 연구)

  • Yun, Pil-Young;Myoung, Hoon;Lee, Jong-Ho;Choung, Pill-Hoon;Kim, Myung-Jin
    • Journal of the Korean Association of Oral and Maxillofacial Surgeons
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    • v.30 no.3
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    • pp.181-185
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    • 2004
  • Malignant tumor have hypoxic cell fraction, which makes radio-resistant and hypoxia in tumor is a result from the blood flow decrease caused by increase in blood flow resistance. Blood viscosity increase is major factor of increased blood flow resistance and it could be attributed to the decrease in blood deformability index. For the evaluation of the change of blood viscosity and blood deformability in oral squamous cell carcinoma, we perform the test of the change of those factors between the normal control group and oral squamous cell carcinoma cell patient group. Relative viscosity measured against distilled water was $5.25{\pm}0.14$ for normal control group, and $5.78{\pm}0.26$ for the SCC patient group and there was statistical significance between the groups. However, there was no significant difference between the groups in blood viscosity between the groups by tumor size (T1+T2 vs T3+T4). Also, there was no significant difference between the normal control group and SCC patient group in blood deformability index and between the groups by tumor size (T1+T2 vs T3+T4). Increase in blood viscosity was confirmed with this study and it can be postulated that modification blood viscosity might contribute to decrease of hypoxia fraction in oral squamous cell carcinoma, thus improve the effect of radiotherapy and it can be assumed that the main factor of blood viscosity increase is not decrease of blood deformability in oral squamous cell carcinoma.

Geotechnical problems in flexible pavement structures design

  • Mato G. Uljarevic;Snjezana Z. Milovanovic;Radovan B. Vukomanovic;Dragana D. Zeljic
    • Geomechanics and Engineering
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    • v.32 no.1
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    • pp.35-47
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    • 2023
  • Deformability of road pavements in the form of ruts represent a safety risk for road users. In the procedures for dimensioning the pavement structure, the requirement that such deformations do not occur is imperatively included, which results in the appropriate selection of elements (material, geometry) of the pavement structure. Deformability and functionality, will depend of the correct design of pavement structure during exploitation period. Nevertheless, there are many examples where deformations are observed on the pavement structure, in the form of rutting at parts of the road with relatively short length, realised in the same climatic and the same geoenvironmental conditions. The performed analysis of deformability led to the conclusion that the level of deformation is a function of the speed of traffic. This effect is observed on city roads, but also outside of urban areas at roads with speed limits are significant, due to the traffic management, traffic jams (intersections, etc.). Still, the lower speed cause greater deformations. The authors tried to describe the deformability of flexible pavement structures, from the aspects of geotechnical problems, as a function of driving speed. Outcome of the analysis is a traffic load correction coefficient, in terms of using the existing methods of flexible pavement structures design.

Deformability of RC Beam-Column Assembles (철근콘크리트 보-기둥 접합부의 연성능력)

  • Lee, Jung-Yoon
    • Proceedings of the Korea Concrete Institute Conference
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    • 2008.04a
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    • pp.193-196
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    • 2008
  • This paper proposes a method to predict the ductility capacity of reinforced concrete beam-column joints failing in shear after the formations of plastic hinges at both ends of the adjacent beams. The current design code divides joints into two categories: Type 1 for structures in non seismically hazard area and Type 2 in seismically hazard area. While there are many researches related to joint shear strength in Type 1, those in regard to joint ductility capacity of Type 2 are scarce. This paper classified the ductility capacity of beam-column joints into column, joint panel, and beam deformability. Since a brittle failure such as shear or bond failure in the columns must be avoided, column deformability was calculated by elastic analysis. The plastic hinges of the adjacent beams affect joint deformability. Therefore, the prediction of joint deformability was calculated with consideration to the degradation of the diagonally compressed concrete due to the strain penetration.

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Behavior of Stud Connection Subjected to both Constant Axial and Various Bending Moments (축력과 휨을 받는 스터드볼트 접합부의 거동에 관한 실험적 연구)

  • 김승훈;이태석;서수연;이리형;홍원기;백승대
    • Proceedings of the Korea Concrete Institute Conference
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    • 2000.10a
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    • pp.535-540
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    • 2000
  • When the stud connection is considered as pin joint in the practical design, it is required to have high deformability. The rotational capacity as well as moment of the connection are evaluated through experimental works. Considered in the test are the reinforcement ratios of concrete member, the magnitude of axial force and connection details. It is shown that the stud connection has some quantity of moment capacity buy on the other hand it has low deformability. The strength and deformability of the connection depend on the axial force and reinforcements around the studs. The strength and ductility of the connection ate increased by using closed C-type.

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Relationship Between Texture and Deformability in Fe-Ni Invar Alloy Strips (Fe-Ni 인바(Invar) 합금 박판의 가공성 향상을 위한 방향성 조직 제어)

  • Park, S.Y.;NamGung, J.;Kim, M.C.;Kim, S.S.;Lee, S.S.;Park, C.G.
    • Transactions of Materials Processing
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    • v.15 no.8 s.89
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    • pp.586-590
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    • 2006
  • 42Ni-Fe Invar alloy strips were fabricated using conventional ingot casting and melt drag casting followed by rolling. Mechanical properties such as tensile strength, elongation and blanking deformability of the strips were evaluated. The properties were strongly depended on fabrication methods. Tensile strength and elongation of all strips were in the range of $40-60kg/mm^{2}$ and 26-35%, respectively, which are enough values for the manufacture of the final products. In some of the strips, however, burrs occurred at deformed surface. The properties of strips were explained in terms of microstructure such as grain size and texture formation during rolling. Additionally, strips by melt drag casting method were compared to those by conventional ingot casting.

Droplet deformability and emulsion rheology: steady and dynamic behavior

  • Saiki Yasushi;Prestidge Clive A.
    • Korea-Australia Rheology Journal
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    • v.17 no.4
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    • pp.191-198
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    • 2005
  • The static and dynamic rheological behavior of concentrated sodium dodecylsulfate (SDS) stabilized, deformability controllable polydimethylsiloxane (PDMS) emulsions is reported and comparisons made with silica (hard sphere) suspensions. Steady-mode measurements indicate 'hard' (viscoelastic) droplets behave as hard spheres, while 'soft' (viscous) droplets induce structural flexibility of the emulsion against shear. Dynamic-mode measurements reveal that viscoelasticity of droplets provides the great magnitude of elasticity for the 'hard' emulsion, while formation of planar films between droplets is the origin of the elasticity of 'soft' emulsions. Combination of steady and dynamic rheological behavior has enabled depiction of droplet structure evolution in relation to the shear stress applied, especially by taking advantage of the normal force that reflects the transient deformation of droplets.

Flexural ductility and deformability of reinforced and prestressed concrete sections

  • Au, Francis T.K.;Leung, Cliff C.Y.;Kwan, Albert K.H.
    • Computers and Concrete
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    • v.8 no.4
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    • pp.473-489
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    • 2011
  • In designing a flexural member for structural safety, both the flexural strength and ductility have to be considered. For this purpose, the flexural ductility of reinforced concrete sections has been studied quite extensively. As there have been relatively few studies on the flexural ductility of prestressed concrete sections, it is not well understood how various structural parameters affect the flexural ductility. In the present study, the full-range flexural responses of reinforced and prestressed concrete sections are analyzed taking into account the nonlinearity and stress-path dependence of constitutive materials. From the numerical results, the effects of steel content, yield strength and degree of prestressing on the yield curvature and ultimate curvature are evaluated. It is found that whilst the concept of flexural ductility in terms of the ductility factor works well for reinforced sections, it can be misleading when applied to prestressed concrete sections. For prestressed concrete sections, the concept of flexural deformability in terms of ultimate curvature times overall depth of section may be more appropriate.

Effects of Cardiotonic Pills® on Cerebrovascular CO2 Reactivity and Erythrocyte Deformability in Normal Subjects: A Pilot Study

  • Sang-Kwan Moon;Han-Gyul Lee;Seungwon Kwon;Seung-Yeon Cho;Seong-Uk Park;Woo-Sang Jung;Jung-Mi Park;Chang-Nam Ko;Ki-Ho Cho
    • The Journal of Korean Medicine
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    • v.44 no.4
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    • pp.87-103
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    • 2023
  • Backgrounds and objectives: Cardiotonic Pills® (CP) are used for vascular diseases such as coronary diseases, atherosclerosis, and cerebral infarction. This study aimed to determine the transient effects of CP on cerebrovascular CO2 reactivity (CVR) and erythrocyte deformability in normal subjects. Methods: This study had a crossover design and included 10 participants who were randomly allocated to 2 groups. The experimental group was given CP with water, while the control group was given only water. CVR was measured by hyperventilation-induced CVR of the middle cerebral artery (MCA) using transcranial Doppler (TCD). Erythrocyte deformability was measured using a Rheoscan-D microfluidic ektacytometer. All measurements were performed prior to and 1, 2, and 3 hours after CP or water administration. Blood pressure and heart rate were also measured before and after administration. Results: CP significantly improved CVR 3 hours after administration in the experimental group compared to the control group (p = 0.042). The corrected blood flow velocity at partial pressure of end-tidal carbon dioxide (PETCO2) = 40mmHg (CV40) was also significantly improved 2 and 3 hours after administration in the CP group compared to the control group (p = 0.036 and p = 0.021, respectively). CP significantly improved erythrocyte deformability 3 hours after administration in the experimental group compared to the control group (p = 0.027). Mean heart rate and mean blood pressure showed no change. Conclusions: This study demonstrated that CP increases CVR and erythrocyte deformability. These results suggested that CP improves cerebral microcirculation which provide evidence for the future use of CP for prevention of ischemic stroke and neurodegenerative diseases.