• Title/Summary/Keyword: deficiency syndrome

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A Review of Studies Using Syndrome Differentiation Questionnaire in Cancer Patients (암 환자 대상 변증 설문지 활용 현황에 대한 문헌고찰)

  • Park, Su Bin;Yoon, Jee-Hyun;Kim, Eun Hye;Lee, Jee Young;Yoon, Seong Woo
    • Journal of Korean Traditional Oncology
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    • v.26 no.1
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    • pp.1-15
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    • 2021
  • Objective: The aim of this review is to analyze the studies using syndrome differentiation questionnaire in cancer patients. Methods: We searched electronic databases including Pubmed, google scholar, Cochrane library, CNKI, KISS, RISS and OASIS. Key words used for searching were cancer, Korean medicine, pattern identification, and questionnaire. Studies using a symptom differentiation questionnaire to cancer patients were selected. Results: 35 studies were enrolled. A total of 17 questionnaires was used. Most of the types of included studies were observational studies, followed by randomized controlled trials (RCTs) and validation studies. The purposes of using questionnaires were rrelation analysis, outcome measurement, evaluating adverse events, subgroup analysis, and questionnaire development. The most used questionnaire was Body Constitution Questionnaire (BCQ), and it was used 8 times, Questionnaire for the Sasang Constitution Classification II (QSCC II) was used 5 times, Constitution in Chinese Medicine Questionnaire (CCMQ), TCM-Symptom Complex Differentiation Questionnaire (TCM-SCDQ), Yin Deficiency Questionnaire were used 4 times, and Qi Blood Yin Yang Deficiency Questionnaire was used twice. BCQ is a questionnaire diagnosing and evaluating yang deficiency, yin deficiency, and blood stasis. It has high reliability, validity, and optimal cut-off value. Conclusion: BCQ is the most used syndrome differentiation questionnaire in cancer-related studies. So, BCQ could be recommended in syndrome differentiation-related cancer studies.

A critic review on the 'medical knowledge of menopausal syndrome' ('폐경기 증후군'에 관한 의학지식의 비판적 고찰)

  • Park, Eun-Ok
    • Research in Community and Public Health Nursing
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    • v.7 no.1
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    • pp.129-137
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    • 1996
  • The purpose of this study is to examine the medicalizing process of menopanse with literature review, and then is to explore the knowledge of 'menopausal syndrome' critically, focused on four critics on the biomedical model which were suggested by Mishler. Although menopause is a natural biological phenomenon, the view of many medical researchers and practitioners is that menopause is a disease. After synthetic estrogen was developel in 1938, physicians did agree on two basic assumptions : menopausal women should be managed by physicians, and medical intervention should be given. Menopouse was defined as a deficiency disease (estrogen difficiency) by Wilson in 60's and is redefined as a cause of disease(for example, osteoporosis, heart disease) at the present. But the other view of non-medical researcher is that 'menopausal syndrome' as a disease is constructed medically. It was reported that Only hot flush and sweating of physical symptoms experienced by menopausal women, were associated with menopause. Symptoms of menopausal syndrome are also related with symptons of aging. So, it cann't conclude that menopausal syndrome is resulted from menopause, and it cann't be only explained that menopausal syndrome is related causally to estrogen deficiency, and only treatment by ERT or HRT is best relevant. It cann't assume that menopausal syndrome is a common phenomenon to all menopause women, because culture affected on women's experience of menopause.

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Vitamin D deficiency and Metabolic Syndrome among Korean Adolescents: Based on Korea National Health and Nutrition Examination Survey V (KNHANES) (청소년의 비타민 D 결핍과 대사증후군 관련요인 분석: 2010년 제5기 1차 국민건강영양조사를 기반으로)

  • Yoo, Ha Na;Kim, Hyeon Suk
    • Journal of the Korean Society of School Health
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    • v.29 no.1
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    • pp.22-32
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    • 2016
  • Purpose: This study is intended to analyze factors of metabolic syndrome and vitamin D deficiency with resources obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) V conducted in 2010. Methods: The subjects were 870 adolescents aged from 10 to 18 who participated in the first KNHANES V. Secondary data analysis was done by Chi-square, ANOVA, correlation analysis and simple linear regression. Results: The influencing factors of metabolic syndrome were vitamin D, systolic blood pressure and diastolic blood pressure, which were statistically significant. Simple linear regression was conducted to identify the influence of vitamin D on the factors related to metabolic syndrome, which showed that waist size (t=-1.97, p<.05), systolic blood pressure (t=-2.88, p<.01), and diastolic blood pressure (t=-5.72, p<.001) were influenced by vitamin D. In addition, each factor decreased by .131, .209, and .355, respectively, when vitamin D increased by one unit. Conclusion: Metabolic syndrome is a factor to be considered in order to improve adolescent health and form adolescent health behaviors. Schools, families, and local communities should cooperate with each other on the foundation of a regular health screening process and systematic health education programs. In addition, it is expected enhanced physical activities and sports club participation can prevent metabolic syndrome and increase vitamin D among adolescent.

Meta-Analysis of AIDS Prevention Programs

  • Kim, Yeon-Hee
    • Korean Journal of Health Education and Promotion
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    • v.3 no.1
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    • pp.129-142
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    • 2001
  • Meta-analysis methods are becoming a central part of research integration in behavioral and medical science studies. The main goal of the meta-analysis is combining the quantitative findings from several studies which address the same research problem and is sharing conclusions in a published report. The purpose of this research is to develop meta-analysis approach to evaluate effectiveness of instructional program design to improve school-age children's knowledge and understanding of Acquired Immune Deficiency Syndrome (AIDS). To achieve this purpose, meta-analysis is applied to analyze and synthesize findings for AIDS instructional programs from several prior studies.

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Prostate Cancer and Metabolic Syndrome: Is there a link?

  • McGrowder, Donovan A.;Jackson, Lennox Anderson;Crawford, Tazhmoye V.
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.1
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    • pp.1-13
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    • 2012
  • Metabolic syndrome has become quite prevalent within our society. Over the past two decades, the prevalence of metabolic syndrome has sharply increased worldwide and it has become a major public health problem in several countries. It is associated with the global epidemic of obesity and diabetes mellitus and imposes numerous cardiovascular risks. Prostate cancer is the second most common cancer among men, surpassed only by non-melanoma skin cancer. A considerable body of evidence exists suggesting that some components of the metabolic syndrome have been associated with the risk of prostate cancer. These components include obesity, an abdominal fat distribution, and hyperinsulinemia. Androgen deprivation therapy (ADT) is the most widely used therapeutic modality in prostate cancer. It changed the body composition and lipid profile of men with prostate cancer. Androgen deficiency is associated with increased levels of total cholesterol, low-density lipoprotein (LDL)-cholesterol, increased production of proinflammatory factors, and increased thickness of the arterial wall and contributes to endothelial dysfunction. The aim of this review is to evaluate the association between metabolic syndrome and prostate cancer and to discuss the implications of androgen deficiency in men with cardiovascular risk factors. A comprehensive literature search was carried out with the use of PubMed from 1980 through 2011, and relevant articles pertinent to metabolic syndrome and prostate cancer are evaluated and discussed.

A Case Report of Proteinuria with Sjogren's Syndrome (쇼그렌 증후군 환자에서의 단백뇨 치험 1례)

  • Jeong, Jong-Jin;Kim, Soo-Yeon;Sun, Seung-Ho;Kim, Byoung-Woo
    • Journal of Pharmacopuncture
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    • v.11 no.4
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    • pp.95-99
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    • 2008
  • Objective Sjogren's Syndrome is a chronic inflamatory disorder characterized by lymphocytic infiltration of lacrimal and salivary gland. It may be associated with renal disease such as tubulonephritis or glomerulonephritis. Proteinuria is a kidney disorder resulting in an abnormally high amount of protein in the urine. When the glomeruli are damaged, proteins of various sizes pass through them and are excreted in the urine. This report is a case of proteinuria with Sjogren's Syndrome. Methods The patient was diagnosed as kidney yang deficiency syndrome and treated with Woogyu-eum, Sa-am acupuncture therapy and bee venom acupuncture therapy. Visual Analog Scale was used to estimate the clinical symptoms. Results Clinical symptoms and proteinuria were improved without steroid therapy. Conclusion Therefore, we concluded that oriental medical therapy may be useful to treat proteinuria with Sjogren's Syndrome.

Reliability Study of Diagnosis System of Oriental Medicine DSOM(r) D.1.1 (한방진단(韓方診斷)시스템 DSOM(r)D.1.1의 신뢰도연구(信賴度硏究))

  • Lee Ji-Hang;Cho Hye-Sook;Kim Mi-Jin;Yeum Yun-Kyung;Yu Ju-Hee;Lee Yong-Tse;Ji Gyue-Yong;Kim Jong-Won;Kim Kyu-Kon;Lee In-Seon
    • The Journal of Korean Medicine
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    • v.27 no.2 s.66
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    • pp.23-35
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    • 2006
  • Objectives : This study examined the reliability of disease mechanism diagnosis, to evaluate items of questionnaires and inquire about the relationships between disease mechanisms and 'diagnosis program' questionnaires used for the objective diagnosis of Oriental medicine in the department of Oriental OB&GYN, Oriental Medical Hospital of Dongeui University. Method : We analyzed the results of questionnaires from 3504 outpatients of OB&GYN disease at the Oriental Medical Hospital of Dongeui University from April 2000 to April 2005. Results & Conclusions : 1. The research questionnaire had 188 questions, the summary questionnaire 137, and the diagnosis questionnaire 80. 2. The reliability of all questionnaires shows above 90% in deficiency of qi, deficiency of Yin, insufficiency of Yang coldness heat syndrome liver and spleen kidney in all, 8 case disease mechanisms. These are higher in the diagnosis questionnaires than in the research questionnaires and the summary questionnaires, except for kidney disease mechanism. 3. Cronbach a of the questionnaires decreased, especially blood deficiency, phlegm, heat syndrome, and insufficiency of Yang; these 4 case disease mechanisms were lower than 0.6. 4. For degree of correspondence of meeting points, both. the diagnosis and the summary questionnaires were above 80% with the exception of the 2 case disease mechanisms heart and blood deficiency. The meeting points of both the diagnosis and research questionnaires were above 80% in the to case disease mechanisms deficiency of qi blood stasis deficiency of Yim insufficiency of Yang damp dryness liver spleen kidney phlegm. 5. The change in the result values of questionnaires was a decreased level of deficiency of qi heat syndrome phlegm damp kidney and raised level of coldness heart disorder of qi dryness 6. The computation degree of disease mechanism in DSOM(r) D.1.1 was much lower on phlegm deficiency of qi heat syndrome disorder of blood, somewhat lower on insufficiency of Yang and higher on coldness than in the two different questionnaires.

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Glucose transport 1 deficiency presenting as infantile spasms with a mutation identified in exon 9 of SLC2A1

  • Lee, Hyun Hee;Hur, Yun Jung
    • Clinical and Experimental Pediatrics
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    • v.59 no.sup1
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    • pp.29-31
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    • 2016
  • Glucose transport 1 (GLUT-1) deficiency is a rare syndrome caused by mutations in the glucose transporter 1 gene (SLC2A1) and is characterized by early-onset intractable epilepsy, delayed development, and movement disorder. De novo mutations and several hot spots in N34, G91, R126, R153, and R333 of exons 2, 3, 4, and 8 of SLC2A1 are associated with this condition. Seizures, one of the main clinical features of GLUT-1 deficiency, usually develop during infancy. Most patients experience brief and subtle myoclonic jerk and focal seizures that evolve into a mixture of different types of seizures, such as generalized tonic-clonic, absence, myoclonic, and complex partial seizures. Here, we describe the case of a patient with GLUT-1 deficiency who developed infantile spasms and showed delayed development at 6 months of age. She had intractable epilepsy despite receiving aggressive antiepileptic drug therapy, and underwent a metabolic workup. Cerebrospinal fluid (CSF) examination showed CSF-glucose-to-blood-glucose ratio of 0.38, with a normal lactate level. Bidirectional sequencing of SLC2A1 identified a missense mutation (c.1198C>T) at codon 400 (p.Arg400Cys) of exon 9.

A Case of Short Bowel Syndrome Due to Strangulated Congenital Internal Hernia in Children (교액성 선천성 내부 탈장에 의해 발생한 단장 증후군 1례)

  • Sim, Chang Eun;Moon, Jin Soo;Kim, Ki Hong;Kim, Han-Seong
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.7 no.2
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    • pp.268-273
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    • 2004
  • Short bowel syndrome in children, most commonly results after extensive bowel resection for necrosis of the bowel. It may be caused by several intestinal catastrophes such as volvulus, hernia and necrotizing enterocolitis. The risk factors on short bowel syndrome are the remaining length of the bowel, the age of onset, the absence of the ileo-cecal valve and the time after resection. Macro and micronutritional deficiencies are the most significant complications of short bowel syndrome. We report a 5 year-old girl, who had a strangulated congenital transmesenteric hernia leading to short bowel syndrome accompanied by iron deficiency anemia.

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