• The Journal of the Society of Korean Medicine Diagnostics
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• v.19 no.3
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• pp.173-184
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• 2015

Objectives The purpose of this study is to understand formation courses of the ten types of LBP (十種腰痛) in Korean medicine through reviewing classic literatures. Methods We summarized sentences describing syndrome differentiation of LBP directly in Uibujeonrok (醫部全錄) and Donguibogam (東醫寶鑑), and then organized similarities and differences among diagnostic factors described in the classic literatures. Results In most of the classics LBP was classified according to the cause but the causes varied depending on the classic literatures. Cheonkeumbang (千金方) tried to suggest a reasonable classification of LBP in a relatively early age. In Dangyesimbeop (丹溪心法) the causes of LBP were divided into 6 factors; qi movement stagnation (氣鬱), dampness-heat (濕熱), kidney deficiency (腎虛), static blood (瘀血), sprain (挫閃) and phlegm accumulation (積痰). It had a lot of influence on the classic literatures published later. Donguibogam was also influenced by the Dangyesimbeop and the ten types of LBP in Donguibogam was similar to the information on the classification shown in Uihakipmun (醫學入門) and Uijongpildok (醫宗必讀). Conclusions We verified universality of the ten types of LBP; kidney deficiency, phlegm-retained fluid (痰飮), food accumulation (食積), sprain, static blood, wind (風), cold (寒), dampness (濕), dampness-heat and qi (氣).

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.1083-1088
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• 2004

This Study was designed to investigate the mechanism of Prescription for Treatment Abundant Expectoration due to Deficiency of Qi(Yukgunja-Tang, YGT) on cerebral hemodynamics [regional cerebral blood f1ow(rCBF) and pial arterial diameter(PAD)] in cerebral ischemia rats. The results were as follows: Both rCBF and PAD were significantly and stably decreased by YGT (10㎎/㎏, i.p.) during the period of cerebral reperfusion, which contrasted with the findings of rapid and marked increase in Control group. Pretreatment with indomethacin(1㎎/㎏, i.p.), an inhibitor of cyclooxygenase and methylene blue(10㎍/㎏, i.p.), an inhibitor of guanylate cyclase significantly but unstably increased the YGT-induced increases in rCBF during the period of cerebral reperfusion. Pretreatment with indomethacin significantly and stably decreased the YGT-induced increases in PAD during the period of cerebral reperfusion, but pretreatment with methylene blue increased unstably the YGT-induced increases in PAD during the period of cerebral reperfusion. In conclusion, the present authors thought that mechanism of YGT on cerebral hemodynamics was connected with guanylate cyclase in cerebral ischemia rats.

• Journal of Oriental Neuropsychiatry
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• v.16 no.2
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• pp.1-11
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• 2005

Objective : This study was to evaluate the clinical improvement of Panic attack and Anticipatory anxiety on Panic Disorder patients after Oriental medical treatment. Methods : We compared post-treatment with pre-treatment on Panic attack and Anticipatory anxiety with Thirty eight Panic Disorder patientsafter Oriental medical treatment - acupunture, herbal medicine, oriental psychotherapy. Results and Conclusions : 1. Foremost herbal medicines were Siwuanshentang(四物安神揚)(39.47%), Qingxinwendantang(情心溫膽揚)(13.16%). Types of demonstration weredeficiency of the heart blood(心血不足)(39.47%), deficiency of qi and blood in the heart and spleen(心脾兩虛)(28.95%), timidity die to insufficiency of qi and deficiency of blood of the heart(心脫虛法)(15.79%), stagnation of phlegm(痰獨阻滯)(13.16%), deficiency of liver-yin and kidney-yin(肝腎陰虛)(2.63%) in order. 2. The physical constitutions in Thirty eight Panic Disorder patients weretwenty nine of Taiyinren(76.3%),six of Shaoyinren(15.8%), three of Shaoyangren(7.9%) in order. 3. This oriental medical treatment was effective in Panic attack from $7.68{\pm}0.87$ to $2.68{\pm}1.613$ and in Anticipatory anxiety from $7.47{\pm}1.006$ to $2.47{\pm}1.841$ in comparison post-treatment with pre-treatment. 4. A percentage of subjective improvement was 72.6%. There were 18.4% in the same, 15.8% in slight improvement, 18.4% in medium improvement, 47.4% in remarkable improvement.

• Journal of Physiology & Pathology in Korean Medicine
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• v.29 no.5
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• pp.434-442
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• 2015

The purpose of this review was to survey the Korean Medicine related papers about women with primary dysmenorrhea in order to develop the clinical protocol of the diagnostic medical device. We searched the literature from 2000 through April 2015 using 5 online databases including Oriental Medicine Advanced Searching Integrated Sysptem (OASIS), Research Information Sharing Service (RISS), DataBase Periodical Information Academic (DBpia) and Korean Medical Database (KMBase). We selected papers to meet the following inclusion criteria: the papers involved dysmenorrhea (excluding secondary dysmenorrhea), published papers (excluding textbook, educational materials, conferences, etc.) and the papers matched search keywords or scope, but excluded papers to meet the following exclusion criteria: the duplicative papers, get out of the keywords and scope and not in english or korean language. Finally we found 17 papers and classified the papers according to the three search purposes which were diagnostic tools for evaluating the menstrual pain, dysmenorrhea' pattern identification and menstrual phase. Out of the 16 studies, 4 studies were focused on the diagnostic tools including Visual Analogue Scale (VAS), Measurement of Menstrual Pain (MMP) and etc. Other 5 studies were aimed at menstrual phase, and the other 7 studies were studied for pattern identification. The VAS has been widely used in research and in clinical practice for the detection of the menstrual pain. Treatments for patients with primary dysmenorrhea can be prescribed in consideration of their patterns of sasang constitution or body constitution as following: Qi stagnation-Blood deficiency, cold dampness, Qi deficiency-blood deficiency and liver-kidney deficiency etc. This results of research will be used as a useful material during plan a clinical study of primary dysmenorrhea and acquisition of good clinical data.

• The Journal of Korean Obstetrics and Gynecology
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• v.31 no.4
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• pp.147-164
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• 2018

Objectives: This study was performed to analyze the pattern identification in infertile women who participated in infertility support program of Cheongju-city. Methods: The project proceeded from October, 2016 to June 2017. Participants filled in the questionnaire which is composed of 33 symptoms before korean medical treatments. Data were collected from 17 participants. We classified symptoms into six pattern identifications based on previous research and rated each answer to score. Results: Throughout the study, the average age of 26 patients was $34.88{\pm}3.19$ years old, the average height was $162.51{\pm}4.99cm$, and average weight was $58.41{\pm}7.88kg$. The average duration of acupuncture treatment was $121.03{\pm}52.73$ days and the average times of acupuncture treatment was $27.42{\pm}10.77$ times. The average number of herbal medicine treatment was $2.65{\pm}0.69$, the majority of it was Chokyungjongok-tang. After the treatment, 3 patients of infertility became pregnant (11.54%) in twenty six patients. By analyzing pattern identification survey papers, We can classify infertile women into 6 pattern identification based on previous research. The majority of participants was identified as Blood deficiency and the other participants were identified as Kidney deficiency, Liver depression, Dampness-phlegm, Qi deficiency and Static blood in order of priority. Most of patients' pattern identification were combined with two kind of pattern identification. In terms of priority, Liver depression combined with Kidney deficiency, Blood deficiency combined with Kidney deficiency, Liver depression combined with Qi deficiency, Liver depression combined with Dampness-phlegm. Conclusions: After the study we confirmed that Korean traditional medicine is a safe treatment for infertile women. Further clinical study about herbal medicines of patients who have combined pattern identification is needed.

• Journal of Korean Medicine Rehabilitation
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• v.21 no.2
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• pp.265-278
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• 2011

Objectives : This trial were conducted to evaluate the efficacy and adverse events of Bofutsusho-san(BTS) and Boiogiot-tang(BOT) by oriental obesity pattern identification on obese subjects, as compared to placebo. Methods : 166 subjects(body mass index ${\geq}25kg/m^2$) were recruited and randomized to receive BT(n=55), FH(n=55) or placebo(n=56) for 8 weeks. Anthropometric factors, serum lipid, glucose, blood pressure(BP), pulse rate, resting metabolic rate and oriental obesity pattern identification questionnaire were measured at baseline and 8 weeks. Adverse events and safety outcome variables were also checked during trials. Results : The frequency of top-scored oriental obesity pattern was ordered by indigestion(食積) > stagnation of the liver qi(肝鬱) > yang deficiency(陽虛) > spleen deficiency(脾虛) > phlegm(痰飮) > blood stasis(瘀血) in subjects. BTS group significantly decreased body weight, body mass index(BMI), waist circumference(WC), body fat mass, total cholesterol and HDL-cholesterol in stagnation of the liver qi(肝鬱) and WC in indigestion(食積). BOT group showed significant decrease of body weight, BMI, WC, and body fat mass in indigestion(食積) not in deficiency(虛症). Adverse events were reported most frequently in yang deficiency(陽虛) by BT group and stagnation of the liver qi(肝鬱) by BOT group. Conclusions : Bofu-tsusho-san was effective in treating obesity with stagnation of the liver qi(肝鬱). Obesity pattern identification could be a useful diagnostic tool predicting treatment effects and adverse events.

• Journal of the Korean Institute of Oriental Medical Informatics
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• v.13 no.1
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• pp.26-38
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• 2007

Interstitial lung disease (ILD) is characterized by progressive scarring of the lung leading to restriction and diminished oxygen transfer. Clinically, the presenting symptoms of ILD are nonspecific (cough and progressive dyspnea on exertion) and are often attributed to other diseases, thus delaying diagnosis and timely therapy. In this study, I analyzed the 10 chinese papers of interstitial lung diseases(ILD). The etiology are body resistance weakness(本虛) and pathogenic factor prevailing(標實). The body resistance weakness(本虛) including deficiency of the lung(肺虛), deficiency of the kidney(腎虛), deficiency of the spleen(脾虛), deficiency of Qi and Yin(氣陰兩虛), pathogenic factor prevailing(標實) including stagnation of phlegm(痰濁), blood stasis(瘀血), noxious heat(熱毒). As an treatment aim at supplementing lung and kidney(益肺腎), resolving phlegm and blood stasis(化痰瘀).

• Herbal Formula Science
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• v.16 no.1
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• pp.15-27
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• 2008

This report describes 46 studies related to the use of Fructus Ponciri Seu Aurantii main blended prescriptions from Dongeuibogam. The following conclusions were reached through investigations on the prescriptions that use Fructus Ponciri Seu Aurantii as a key ingredient. 1. 19.6% of feces recorded the largest number of clinical frequency of the prescriptions in therapeutic use when Fructus Ponciri Seu Aurantii was taken as a monarch drug in prescriptions. In addition, 13.0% of each of a cough and an abdominal mass with distention and pain ranked second. 2. Prescriptions that utilize Fructus Ponciri Seu Aurantii as the main ingredient are used in the treatmeant of 5 diseases related to each of feces and an abdominal mass with distention and pain, and they are also used for treating different types of diseases related to the following ; a cough, a chest, ribs, eyes, the fullness in the chest, Qi, skin areas. 3. In the view of the causative agent of a disease, the prescriptions which are compounded with Fructus Ponciri Seu Aurantii as a monarch drug are related to endogenous agents such as seven emotion, food, deficiency, exogenous agents such as wind-cold pathogen, heat and non-endo-exopathogcnic factors like diseases due to external factors, poison. And in the view of the pathology of a disease, they are applied to the viscera pathology related to the lung, the spleen and stomach, the pathology of Qi and blood related to the reversed flow of Qi, the congestion of Qi, the deficiency of blood, the obstruction of Qi and blood, and the pathology about the retention of phlegm and fluid related to phlegm stagnation. 4. The dosage of Fructus Ponciri Seu Aurantii is 1.25pun(about 0,47g) to 2jeon(about 7.5g), however 1jeon(about 3.75g) has been taken the most for clinical application. 5. We can find out that according to herbs or prescriptions blended with itself, Fructus Ponciri Seu Aurantii makes a variety of functions to penetrate and remove stagnation, regulate Qi flow, relieve stagnation, expell wind and get rid of pain.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.5 no.1
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• pp.27-44
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• 1992

The cause and mechanism of eye diseases are follow in biblography. The etiological factor of eye diseases are nearly caused by heat. It is important to distinguish deficiency and substance. In external etiologic factors wind-fever is most of all in six exogenous factors. In internal etiologic factors xu(deficiency) of kidney, blood and fire of seven emotions are lots. In factors other than the internal and external, eating greasy food and hyper-caloric food are a lot of case. In relation with the yin-yang andxu-shi, ther are a lot of eye diseases symptom as dark-dizziness due to the yin-xu of hepatic-kidney. According to eight principles of differentiation of syndromes, syndromes of exterior, heat, shi, almost fall into the category of yang and syndromes of interior, cold, xu, nearly fall into the category of yin. In interior treatment, inducing wind and clearing heat, using Qi and tonifying blood, tonifying and suing of hepatic-kid ney are useful and often used treatment.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.29 no.4
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• pp.1-13
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• 2016

Objectives : The purpose of this study is to compare hair and alopecia of Korean Medicine with those of western medicine. Methods : We studied relationships between hair and essense(精), qi(氣), blood(血), five vicera(五臟) and meridians(經絡) through literature review about hair and alopecia. We compared Korean medicine with western medicine on physiology of hair and treatment of alopecia based on the study. Results & Conclusion : 1. Congenital essense(先天之精) is related with genetic factor and acquired essence(後天之精) is connected with nutritional factor. Defending function of Defense qi(衛氣) is related with immune reaction and qi stagnation(氣鬱) is associated with stress reaction. Atrophy of vascular tissues observed in alopecia scalp means deep relationship between blood(血) and alopecia, further deficiency of blood can cause telogen effluvium. 2. Kidney qi(腎氣) is related with inhibiting combination of Androgen receptor and Dihydrotestosterone(DHT) or activating hair growth factior. Pi(脾) is connected with alopecia seborrheica caused by damp-heat(濕熱) and alopecia areata caused by excessive prudence(思慮過度). Heart(心) is associated with atrophy in vascular tissue of scalp and liver(肝) is connected with metabolism. 3. Armpit hair and pubic hair as secondary sex characteristics are realated with Yangming Meridian(陽明經) and beard and hair at crown part where Type II $5{\alpha}$-reductase is activated much are associated with Taiyang Meridian(太陽經). 4. Juglandis Semen pharmacopuncture and Ganoderma lucidum pharmacopucture have better effects on inhibit $5{\alpha}$-reductase than Finasteride. Minoxidil and PRP are similar with promoting blood flow and removing stasis(活血祛瘀). Seven-star needling(七星針) is similar with microneedling. 5. Alopecia can be caused by due to lack of circulation Views we need solution to improve circulation coincide in opinion with Korean Medicine and Western medicine.